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AVDSHWLVMEGAGPRARYRSRLAGAGRHLPPTHLSTRDLMASTRHNTHIDLERLTGIRDRRVSTGDEDSY SLATAAAVDCLDRAGQDAAGLDVVINCSITKFRDGLTQWMEPTMSAAVARAIGAEHAMTFDLSNACAGML TGATVLNNWIRQGTVQRGLVVSGEYISQLGQNAARHIRSIMSKELACLTLGDAGAALLFERAPADSAAGI SLAGFTTVADHSRLCLAYPKGDDPGARMFTDSRGIQRAAIAATPYLLHEVLDAAGISIGDIDHVITHQTS ARAIRKGMAALTESFGGGPRHDAVITVDRYGNTASTTHTVALVEELEAGRIRAGETIALIALASGLEIGV VLLTLDEELVNRYGHRD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2540 | - | - | 100% (368) | Beta-ketoacyl-acyl-carrier-protein synthase I |
| M. gilvum PYR-GCK | Mflv_2539 | - | 2e-13 | 25.51% (294) | 3-oxoacyl-(ACP) synthase III |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0547c | fabH | 4e-16 | 27.33% (300) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. tuberculosis H37Rv | Rv0533c | fabH | 4e-16 | 27.33% (300) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1141c | - | 3e-13 | 25.00% (328) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. marinum M | MMAR_3474 | - | 1e-162 | 79.95% (364) | ketoacyl-acyl carrier protein synthase III |
| M. avium 104 | MAV_4612 | - | 2e-20 | 27.18% (309) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. smegmatis MC2 155 | MSMEG_3953 | - | 1e-145 | 74.50% (349) | hypothetical protein MSMEG_3953 |
| M. thermoresistible (build 8) | TH_1179 | - | 1e-155 | 77.20% (364) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0632 | fabH | 6e-16 | 24.39% (328) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. vanbaalenii PYR-1 | Mvan_1354 | - | 8e-07 | 23.47% (294) | 3-oxoacyl-(ACP) synthase III |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2540|M.gilvum_PYR-GCK MAVDSHWLVMEG-AGPRARYRSRLAGAGRHLPPTHLSTRDLMASTRHNTH
MMAR_3474|M.marinum_M --MTRHWLVMETPNGPHAPYVTRIAGAGRHLPETHLTTDELMSSTRHRTH
TH_1179|M.thermoresistible__bu --MRTQWLLTEDAEADGAPFRTRLAGAGRHLPVTRLSTDDLTARTRHRTT
MSMEG_3953|M.smegmatis_MC2_155 --MGPHWLVMDAADEASSPFRTRIAAAGRCLPKTRLTTSELMSETRHNTH
MAV_4612|M.avium_104 ---------MKQISATSGPTNIGLLSVGSYRPQRAVTNDELCQNIDSSDE
MUL_0632|M.ulcerans_Agy99 ---------MTEIATTSGISSVGLLSVGAYRPTRVVTNDEICENIDSSDE
Mb0547c|M.bovis_AF2122/97 ---------MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSSDE
Rv0533c|M.tuberculosis_H37Rv ---------MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSSDE
MAB_1141c|M.abscessus_ATCC_199 ---------MTDIAEITGINKIGLLSLGAYRPERVVTNDEICERIESSDE
Mvan_1354|M.vanbaalenii_PYR-1 -----------------MTTTVSLVDVSVHLPGEPIGADHYAQFAESDDL
: . * : .
Mflv_2540|M.gilvum_PYR-GCK IDLERLTGIRDRRVSTGDEDSYSLATAAAVDCLDRAGQDAAG-LDVVINC
MMAR_3474|M.marinum_M IDLERLTGIRERRVSVGDEDSYSLATAAALDALAAARQDPAS-LDVVINC
TH_1179|M.thermoresistible__bu IDLERLTGIRERRISVGDEDSYSLATAAALDCLHRADRAAES-VEVVINC
MSMEG_3953|M.smegmatis_MC2_155 IDLERLTGIRERRVSLGEDDSYSLATKAALDCLEKADRSADS-VEVVINC
MAV_4612|M.avium_104 WIYSR-TGIKTRRFAARDESTASMATEAGREAIAKAGLEASD-IDCVVVA
MUL_0632|M.ulcerans_Agy99 WIYSR-TGIKTRRFAAPEESAASMAIEASREAIAKAALTGSD-IDGVIVA
Mb0547c|M.bovis_AF2122/97 WIYTR-TGIKTRRFAADDESAASMATEACRRALSNAGLSAAD-IDGVIVT
Rv0533c|M.tuberculosis_H37Rv WIYTR-TGIKTRRFAADDESAASMATEACRRALSNAGLSAAD-IDGVIVT
MAB_1141c|M.abscessus_ATCC_199 WIYTR-TGIKTRRFAADEETAQTLAIEAGRKAIANALLTGAE-IDAVIVA
Mvan_1354|M.vanbaalenii_PYR-1 RDNVMFRAPHLRHHVDPETSAIDMAEQAAQGLIARHGQDAVTGADVLITH
. : *: : : :* * : : ::
Mflv_2540|M.gilvum_PYR-GCK SITKFRDGLTQWMEPTMSAAVARAIGAEHAMTFDLSNA-CAGMLTGATVL
MMAR_3474|M.marinum_M SITKFRGGLTQWLEPSMSSAVARGIGAHRAMTFDVSNA-CAGMLTGVTIL
TH_1179|M.thermoresistible__bu SITKFRDGLTQWLEPPMSTAVARAIGADTAMTFDLSNA-CAGMLTGVSIL
MSMEG_3953|M.smegmatis_MC2_155 SITKFHGGLTQYLEPTMSSDVAHAIGARDAMTFDISNA-CAGMLTGVMVL
MAV_4612|M.avium_104 TSTHFLQ------TPACGPAVAAALGATGVPAFDISAG-CAGFGYALGVA
MUL_0632|M.ulcerans_Agy99 TSTHFLQ------TPACAPIVAAALGCQNVPAFDISAG-CSGFGHALGIA
Mb0547c|M.bovis_AF2122/97 TNTHFLQ------TPPAAPMVAASLGAKGILGFDLSAG-CAGFGYALGAA
Rv0533c|M.tuberculosis_H37Rv TNTHFLQ------TPPAAPMVAASLGAKGILGFDLSAG-CAGFGYALGAA
MAB_1141c|M.abscessus_ATCC_199 TSTHYLQ------TPASAPAVATALGAQGVPAFDLSAG-CAGFGYAVGVA
Mvan_1354|M.vanbaalenii_PYR-1 TQLPDMP------FYGAGGGMAHRLGMKPNWVIDLHNGGCAAFLLGLKLA
: . :* :* :*: . *:.: .
Mflv_2540|M.gilvum_PYR-GCK NNWIRQGTVQRGLVVSGE----YISQLGQNAARHIRSIMSKELACLTLGD
MMAR_3474|M.marinum_M NNWIRQGVVERGLVVSGE----YISQLSHNAARHIRNIMSKELASLTLGD
TH_1179|M.thermoresistible__bu NNWIRQGVVERGMVVSGE----YISQLTANAAQHIRTIMSKELASLTLGD
MSMEG_3953|M.smegmatis_MC2_155 NTWIRQGLVARGMVVSGE----YISQLGQNAAKHIRTVLSKELASLTLGD
MAV_4612|M.avium_104 ADMVRGGTAGKVLVLGSE----KLSPTVDMTDRSNCFIFADGAAGVVVGE
MUL_0632|M.ulcerans_Agy99 ADMIRGGSAATILVIGTE----KLSPTVDMTDRSNCFIFVDGAASVLVGH
Mb0547c|M.bovis_AF2122/97 ADMIRGGGAATMLVVGTE----KLSPTIDMYDRGNCFIFADGAAAVVVGE
Rv0533c|M.tuberculosis_H37Rv ADMIRGGGAATMLVVGTE----KLSPTIDMYDRGNCFIFADGAAAVVVGE
MAB_1141c|M.abscessus_ATCC_199 GDMIRGGSASKVLVIGSE----KLSPALDMTDRGNCFIFGDGAGAVVVGE
Mvan_1354|M.vanbaalenii_PYR-1 RNLLASGEGRTALIAVVQNAAGQIFEQPTIRRRAQAAVPGDGAAIGLVTV
: * :: : : : : . . :
Mflv_2540|M.gilvum_PYR-GCK AGAALLFERAPADSAAGISLAGFTTVADHSRLCLAYPKGDDPGARMFTDS
MMAR_3474|M.marinum_M AGAALLLERAPVG-SAGIALAGFTTVADYSRLCLAYPRGHDPGARMFTNA
TH_1179|M.thermoresistible__bu AGAALLLERAYPG-SGSIRLSGFTTIADHSRLCLAYPKGPEPGARMFTDS
MSMEG_3953|M.smegmatis_MC2_155 AGAALLLERVPAG-GSGITLAGFTTIADYSRLCLAYPKGRDPGARMFTDS
MAV_4612|M.avium_104 TPTQGIGPTVWGS--DGTQATAIRQDIDWMDYLDRP---TGPRPFLRLEG
MUL_0632|M.ulcerans_Agy99 SPIQGIGPTVWGS--DGEQAAAIRQDIDWISHAENP---AGPRPFLRMEG
Mb0547c|M.bovis_AF2122/97 TPFQGIGPTVAGS--DGEQADAIRQDIDWITFAQNP---SGPRPFVRLEG
Rv0533c|M.tuberculosis_H37Rv TPFQGIGPTVAGS--DGEQADAIRQDIDWITFAQNP---SGPRPFVRLEG
MAB_1141c|M.abscessus_ATCC_199 TAEQGIGPTVWGS--DGSQSNAIRQDIDWMDFAAAPDP-EGPRPYLRIEG
Mvan_1354|M.vanbaalenii_PYR-1 SDESPILDVECRT--YGEYAGDMTIAVDPPRKWWQAGPGEGCIGFTESKI
: : . : * .
Mflv_2540|M.gilvum_PYR-GCK RGIQRAAIAATPYLLHEVLDAAGISIGDIDHVITHQTSARAIRKGMAALT
MMAR_3474|M.marinum_M RAIHQAAMANTPLLLEEVLETAGISIHDIDHVITHQTSARAIRKGMAKMS
TH_1179|M.thermoresistible__bu RGIQRAAIAATPVLLQEVLDQTGLSIHDIDHVITHQTSARAIRKGMRRIA
MSMEG_3953|M.smegmatis_MC2_155 RAIHRAAITNTPVLLREVLDTAGISIDDIDHVITHQTSARAIKKGMAVMA
MAV_4612|M.avium_104 SAVFRWAAFEMGKVGQQAMDAAGVRPDEIDVFLPHQANSRIN----EILA
MUL_0632|M.ulcerans_Agy99 TAVFRWAAFEMGKVGQQAMDAAGVKPDEIDVFIPHQANSRIN----ELLT
Mb0547c|M.bovis_AF2122/97 PAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRIN----ELLV
Rv0533c|M.tuberculosis_H37Rv PAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRIN----ELLV
MAB_1141c|M.abscessus_ATCC_199 TSVFRWAAFEMGKVGQRAMEAAKVGPEQIDVFVPHQANTRIN----ELLA
Mvan_1354|M.vanbaalenii_PYR-1 TKVLARGNRQVPEVSYAVCDRIGLPPKDVDLFVTNQPNRVFLR----NWR
: . : . : : ::* .:.:*..
Mflv_2540|M.gilvum_PYR-GCK ESFGGGPRHDAVITVDRYGNTASTTHTVALVEELEAGRIRAGETIALIAL
MMAR_3474|M.marinum_M EAFGDKPRHDAVITVDRYGNTASTTHTVALIEELTAGRIVAGERIALIAL
TH_1179|M.thermoresistible__bu DEFGGTPAHDAVITVDKYGNTASTTHTVALVDELEAGGIAPGETIALIAL
MSMEG_3953|M.smegmatis_MC2_155 AEFGDHPRHDAVITVDRYGNTASTTHTVALIEELEARRIEPGETVALIAL
MAV_4612|M.avium_104 KSLELRPDAVIANDIEHTGNTSAASIPLAMAEVLATGAAKAGDLALLIGY
MUL_0632|M.ulcerans_Agy99 KNLQLRPDAVIANDIEHTGNTSAASIPLAMAELLATGAAKPGDLALLIGY
Mb0547c|M.bovis_AF2122/97 KNLQLRPDAVVANDIEHTGNTSAASIPLAMAELLTTGAAKPGDLALLIGY
Rv0533c|M.tuberculosis_H37Rv KNLQLRPDAVVANDIEHTGNTSAASIPLAMAELLTTGAAKPGDLALLIGY
MAB_1141c|M.abscessus_ATCC_199 KNLHLRADAVIANDIEHTGNTSAASVPLAMETLLSTGAAKPGDLALLIGY
Mvan_1354|M.vanbaalenii_PYR-1 EALELPP-ERHVDTFDECGNLFAAGIPVNLDRAVREGRVKRGDTVLMAAF
: . . .:. ** :: .: : : *: : .
Mflv_2540|M.gilvum_PYR-GCK ASGLEIGVVLLTLDEELVNRYGHRD
MMAR_3474|M.marinum_M ASGLEIGIVLLTLDEEMVSRYGHSD
TH_1179|M.thermoresistible__bu ASGLEIGIVLLTLDEEMVGRHGNRG
MSMEG_3953|M.smegmatis_MC2_155 ASGLEIGIHLADR------------
MAV_4612|M.avium_104 GAGLSYAAQVVRLPPG---------
MUL_0632|M.ulcerans_Agy99 GAGLSYAAQVVRMPNS---------
Mb0547c|M.bovis_AF2122/97 GAGLSYAAQVVRMPKG---------
Rv0533c|M.tuberculosis_H37Rv GAGLSYAAQVVRMPKG---------
MAB_1141c|M.abscessus_ATCC_199 GAGLSYAAQVVRMPPVPFE------
Mvan_1354|M.vanbaalenii_PYR-1 AHAGDFAAAAALRWGGRD-------
. . . .