For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTTTVSLVDVSVHLPGEPIGADHYAQFAESDDLRDNVMFRAPHLRHHVDPETSAIDMAEQAAQGLIARHG QDAVTGADVLITHTQLPDMPFYGAGGGMAHRLGMKPNWVIDLHNGGCAAFLLGLKLARNLLASGEGRTAL IAVVQNAAGQIFEQPTIRRRAQAAVPGDGAAIGLVTVSDESPILDVECRTYGEYAGDMTIAVDPPRKWWQ AGPGEGCIGFTESKITKVLARGNRQVPEVSYAVCDRIGLPPKDVDLFVTNQPNRVFLRNWREALELPPER HVDTFDECGNLFAAGIPVNLDRAVREGRVKRGDTVLMAAFAHAGDFAAAAALRWGGRD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1354 | - | - | 100% (338) | 3-oxoacyl-(ACP) synthase III |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0547c | fabH | 9e-11 | 25.15% (330) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. gilvum PYR-GCK | Mflv_2540 | - | 6e-07 | 23.47% (294) | Beta-ketoacyl-acyl-carrier-protein synthase I |
| M. tuberculosis H37Rv | Rv0533c | fabH | 9e-11 | 25.15% (330) | 3-oxoacyl-(acyl carrier protein) synthase III |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2167 | - | 1e-120 | 58.38% (334) | putative 3-oxoacyl-ACP synthase III |
| M. marinum M | MMAR_0879 | fabH | 4e-13 | 23.81% (336) | 3-oxoacyl- |
| M. avium 104 | MAV_4422 | - | 1e-162 | 78.81% (335) | 3-oxoacyl-ACP synthase III |
| M. smegmatis MC2 155 | MSMEG_1490 | - | 1e-170 | 83.93% (336) | 3-oxoacyl-ACP synthase III |
| M. thermoresistible (build 8) | TH_0207 | - | 1e-125 | 62.28% (334) | 3-oxoacyl-ACP synthase III |
| M. ulcerans Agy99 | MUL_0632 | fabH | 6e-13 | 23.81% (336) | 3-oxoacyl-(acyl carrier protein) synthase III |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1354|M.vanbaalenii_PYR-1 ----------------MTTTVSLVDVSVHLPGEPIGADHYAQFAESDDLR
MSMEG_1490|M.smegmatis_MC2_155 --------------MNTTTPVSLVDVSTYLPGEPIGAEYYAQFAETDDLR
MAV_4422|M.avium_104 ---------------MNASTVSLIDVASYLPGEPIPADYYAQFAESDDLR
TH_0207|M.thermoresistible__bu ------------MRKTPSPTVSLVDVASYLPENRMPASWYAEHAESDDLR
MAB_2167|M.abscessus_ATCC_1997 ------------------MSVSIFDISSYLPENRVSAEYFAQYAKDDDLA
Mb0547c|M.bovis_AF2122/97 --------MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSS---
Rv0533c|M.tuberculosis_H37Rv --------MTEIATTSGARSVGLLSVGAYRPERVVTNDEICQHIDSS---
MMAR_0879|M.marinum_M --------MTEIATTSGISSVGLLSVGAYRPTRVVTNDEICENIDSS---
MUL_0632|M.ulcerans_Agy99 --------MTEIATTSGISSVGLLSVGAYRPTRVVTNDEICENIDSS---
Mflv_2540|M.gilvum_PYR-GCK MAVDSHWLVMEGAGPRARYRSRLAGAGRHLPPTHLSTRDLMASTRHN--T
: . . : * : .
Mvan_1354|M.vanbaalenii_PYR-1 DNVMFRAP--HLRHHVDPETSAIDMAEQAAQGLIARHGQDAVTGADVLIT
MSMEG_1490|M.smegmatis_MC2_155 DNLMFRAP--RFRHHVAPDETATDMIERAAAGLIERHGADTVQGADVLIT
MAV_4422|M.avium_104 DNVMFRAP--KYRHHVGHDESSIDMIERAAQGLIERHGHDVIEGADVLIT
TH_0207|M.thermoresistible__bu DNPMFAPP--EYRHHSAIDESNVDMIERAAAGLLGRYGPDVLRDVDVLLT
MAB_2167|M.abscessus_ATCC_1997 ENVMFRSP--AYRHHVANDESAVDMAERAVAGLRERHGATVLDEVDILLT
Mb0547c|M.bovis_AF2122/97 DEWIYTRTGIKTRRFAADDESAASMATEACRRALSNAGLSAAD-IDGVIV
Rv0533c|M.tuberculosis_H37Rv DEWIYTRTGIKTRRFAADDESAASMATEACRRALSNAGLSAAD-IDGVIV
MMAR_0879|M.marinum_M DEWIYSRTGIKTRRFAAPEESAASMAIEASREAIAKAALTGSD-IDGVIV
MUL_0632|M.ulcerans_Agy99 DEWIYSRTGIKTRRFAAPEESAASMAIEASREAIAKAALTGSD-IDGVIV
Mflv_2540|M.gilvum_PYR-GCK HIDLERLTGIRDRRVSTGDEDSYSLATAAAVDCLDRAGQDAAG-LDVVIN
. : . *: : .: * . . * ::
Mvan_1354|M.vanbaalenii_PYR-1 HTQLPDMP------FYGAGGGMAHRLGMKPNWVIDLHNGGCAAFLLGLKL
MSMEG_1490|M.smegmatis_MC2_155 HTQMPDMP------FYGGGGGIAHRLGMKPNWVIDLHNGGCAAFVLGMKV
MAV_4422|M.avium_104 HTQVPDMA------FYGQGGGIAHRLGMRPSWVLDLNNGGCAAFVLALNV
TH_0207|M.thermoresistible__bu HSQMPDLP------IVGAGGEVAHRLGMNPEWIIDVHNSGCASFVQMIKL
MAB_2167|M.abscessus_ATCC_1997 HTQLPDLP------FVGCGGEVANRLQIRPEWILDVHNGGCVSFVLMLKL
Mb0547c|M.bovis_AF2122/97 TTNTHFLQ------TPPAAPMVAASLGAKGILGFDLS-AGCAGFGYALGA
Rv0533c|M.tuberculosis_H37Rv TTNTHFLQ------TPPAAPMVAASLGAKGILGFDLS-AGCAGFGYALGA
MMAR_0879|M.marinum_M ATSTHFLQ------TPACAPIVAAALGCQNVPAFDIS-AGCSGFGHALGI
MUL_0632|M.ulcerans_Agy99 ATSTHFLQ------TPACAPIVAAALGCQNVPAFDIS-AGCSGFGHALGI
Mflv_2540|M.gilvum_PYR-GCK CSITKFRDGLTQWMEPTMSAAVARAIGAEHAMTFDLS-NACAGMLTGATV
: . :* : . :*: .* .:
Mvan_1354|M.vanbaalenii_PYR-1 ARNLLASGEGRTALIAVVQNAAGQ-----IFEQPTIRRRAQAAVPGDGAA
MSMEG_1490|M.smegmatis_MC2_155 ARTLLASGEGHTAVIAVAQNAAGQ-----IFDQETIRRKAQASVPGDGAA
MAV_4422|M.avium_104 ARTLLSSGQGRTALIAIAQNAAGQ-----FFDQPTIRRKAQAAVPGDGAA
TH_0207|M.thermoresistible__bu ARRLLSSGSGRKALIACSAGAAGK-----VFEQPEVRKLAQSSVPGDGAA
MAB_2167|M.abscessus_ATCC_1997 VQQMMVSSSARSALIVNIQNAAGQ-----IFVQEQVRSTAQASIPGDGAT
Mb0547c|M.bovis_AF2122/97 AADMIRGGGAATMLVVGTEKLS---------PTIDMYDRGNCFIFADGAA
Rv0533c|M.tuberculosis_H37Rv AADMIRGGGAATMLVVGTEKLS---------PTIDMYDRGNCFIFADGAA
MMAR_0879|M.marinum_M AADMIRGGSAATILVIGTEKLS---------PTVDMTDRSNCFIFADGAA
MUL_0632|M.ulcerans_Agy99 AADMIRGGSAATILVIGTEKLS---------PTVDMTDRSNCFIFVDGAA
Mflv_2540|M.gilvum_PYR-GCK LNNWIRQGTVQRGLVVSGEYISQLGQNAARHIRSIMSKELACLTLGDAGA
: . :: : : . *..:
Mvan_1354|M.vanbaalenii_PYR-1 IGLVTVSDESPILDVECRTYGEYAGDMTIAVDPPRKWWQAGPGEGCIGFT
MSMEG_1490|M.smegmatis_MC2_155 VGLVTVSDASPILDVECRTYGEYAGDMTIASDPPRKWWQPGPGEGYIGFT
MAV_4422|M.avium_104 VGLVTVGDSSPVLDVECRSYGEYAGEMTLSYDPPRKWWQAGPGEGSIGFT
TH_0207|M.thermoresistible__bu VGLLEVSDRSPVLDVECRYFGQNAVDMTLETDPPRRWWQAGPGEGHVGFN
MAB_2167|M.abscessus_ATCC_1997 ATLITRDGGSPVLGIETRNFGEFAGDMTYAVTPHRKYWEAGSGQGRVAFT
Mb0547c|M.bovis_AF2122/97 AVVVG---ETPFQGIGPTVAGSDGEQADAIRQDIDWITFAQNPSGPRPFV
Rv0533c|M.tuberculosis_H37Rv AVVVG---ETPFQGIGPTVAGSDGEQADAIRQDIDWITFAQNPSGPRPFV
MMAR_0879|M.marinum_M SVLVG---HSPIQGIGPTVWGSDGEQAAAIRQDIDWISHAENPAGPRPFL
MUL_0632|M.ulcerans_Agy99 SVLVG---HSPIQGIGPTVWGSDGEQAAAIRQDIDWISHAENPAGPRPFL
Mflv_2540|M.gilvum_PYR-GCK ALLFERAPADSAAGISLAGFTTVADHSRLCLAYPK-----GDDPGARMFT
:. . .: . . * *
Mvan_1354|M.vanbaalenii_PYR-1 ESKITKVLARGNRQVPEVSYAVCDRIGLPPKDVDLFVTNQPNRVFLRN--
MSMEG_1490|M.smegmatis_MC2_155 ESKITKVLARGNRQVPEVSYAVCDRIGIHPRDIDLFVTNQPNRVFLRN--
MAV_4422|M.avium_104 DSKITKVLARGNRQVPEVALAVCDRIGLPAKDIDLLVTNQPNRAFLRN--
TH_0207|M.thermoresistible__bu EGKIMKVLARGNRMVPQVVRAVCDRIGVKPVDLDLLITNQPNRLLLRN--
MAB_2167|M.abscessus_ATCC_1997 EHKISKVLARGNRMVPEVALAVCDRIGIASTDLDALVTNQPNRIFLRN--
Mb0547c|M.bovis_AF2122/97 RLEGPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRINEL--
Rv0533c|M.tuberculosis_H37Rv RLEGPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRINEL--
MMAR_0879|M.marinum_M RMEGTAVFRWAAFEMGKVGQQAMDAAGVKPDEIDVFIPHQANSRINEL--
MUL_0632|M.ulcerans_Agy99 RMEGTAVFRWAAFEMGKVGQQAMDAAGVKPDEIDVFIPHQANSRINEL--
Mflv_2540|M.gilvum_PYR-GCK DSRG--IQRAAIAATPYLLHEVLDAAGISIGDIDHVITHQTSARAIRKGM
. : . : . * *: ::* .:.:*.. .
Mvan_1354|M.vanbaalenii_PYR-1 --WREALEL-PPERHVDTFDECGNLFAAGIPVNLDRAVREGRVKRGDTVL
MSMEG_1490|M.smegmatis_MC2_155 --WREALEL-PAERHVDTFDTCGNLFGAGIPINFDRAVTNGRVKAGDTVL
MAV_4422|M.avium_104 --WREALEL-PPARHLDTFDECGNLFGAGIPVNLDRAISEQRIKAGEVVM
TH_0207|M.thermoresistible__bu --WDEALEL-PRERHCDTFHEAGNLFAVAMPHNLQTAIEDGRIAAGDVVM
MAB_2167|M.abscessus_ATCC_1997 --WRDALQL-PKEKHPDTFDECGNLFGVGIPHTLDKAIAERQVRPGDAVM
Mb0547c|M.bovis_AF2122/97 --LVKNLQLRPDAVVANDIEHTGNTSAASIPLAMAELLTTGAAKPGDLAL
Rv0533c|M.tuberculosis_H37Rv --LVKNLQLRPDAVVANDIEHTGNTSAASIPLAMAELLTTGAAKPGDLAL
MMAR_0879|M.marinum_M --LTKNLQLRPDAVIANDIEHTGNTSAASIPLAMAELLATGAAKPGDLAL
MUL_0632|M.ulcerans_Agy99 --LTKNLQLRPDAVIANDIEHTGNTSAASIPLAMAELLATGAAKPGDLAL
Mflv_2540|M.gilvum_PYR-GCK AALTESFGGGPRHDAVITVDRYGNTASTTHTVALVEELEAGRIRAGETIA
. : * .. ** .. . : : *:
Mvan_1354|M.vanbaalenii_PYR-1 MAAFAHAGDFAAAAALRWGGRD-----------------
MSMEG_1490|M.smegmatis_MC2_155 MAAFAHAGDFAGAAAVRWGGRG-----------------
MAV_4422|M.avium_104 MAAFAHAGDFAGAAAVRWGGRGGC---------------
TH_0207|M.thermoresistible__bu LAGFANAGDFAGAAAIQWGGRPRSVQTQSADTRSGEASS
MAB_2167|M.abscessus_ATCC_1997 LAGFAHAGDYAAAAAVRWGGRGQ----------------
Mb0547c|M.bovis_AF2122/97 LIGYGAGLSYAAQVVRMPKG-------------------
Rv0533c|M.tuberculosis_H37Rv LIGYGAGLSYAAQVVRMPKG-------------------
MMAR_0879|M.marinum_M LIGYGAGLSYAAQVVRMPNS-------------------
MUL_0632|M.ulcerans_Agy99 LIGYGAGLSYAAQVVRMPNS-------------------
Mflv_2540|M.gilvum_PYR-GCK LIALASGLEIGVVLLTLDEELVNRYGHRD----------
: . . . . .