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PPALRVYCVPHAIGSASLYGEWSDRLPSWVRVVPLEYPGHGRRFGQPPLTAIDEIARVFARELAADLDGP YALFGHSMGALVTFELARELRQQRAPLPVKLYAAASRPPVVFWPPNRGQYLSALSDSALLSRLNSFGGTP SELLHNAELMDLMLPIARADLTACEEYLYRPAPPLSCPITALGGVGDVTFDQSELTRWGEMTSATFEVVA MPGGHFFVRTAAALLSWLAEDFRRVLGFSR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0367 | - | - | 100% (241) | thioesterase |
| M. marinum M | MMAR_3693 | - | 2e-24 | 33.20% (244) | thioesterase |
| M. marinum M | MMAR_1778 | tesA | 1e-21 | 31.63% (215) | thioesterase TesA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2953 | tesA | 1e-21 | 33.64% (217) | thioesterase TESA |
| M. gilvum PYR-GCK | Mflv_1276 | - | 4e-26 | 31.78% (214) | thioesterase |
| M. tuberculosis H37Rv | Rv2928 | tesA | 1e-21 | 33.64% (217) | thioesterase TESA |
| M. leprae Br4923 | MLBr_02359 | - | 3e-19 | 28.84% (215) | thioesterase |
| M. abscessus ATCC 19977 | MAB_2033 | - | 1e-26 | 34.10% (217) | thioesterase |
| M. avium 104 | MAV_2010 | - | 9e-19 | 30.28% (218) | phenyloxazoline synthase mbtb |
| M. smegmatis MC2 155 | MSMEG_4514 | - | 2e-18 | 28.10% (210) | thioesterase domain-containing protein |
| M. thermoresistible (build 8) | TH_4495 | - | 6e-18 | 29.28% (222) | PUTATIVE Thioesterase |
| M. ulcerans Agy99 | MUL_3636 | - | 2e-23 | 32.79% (244) | thioesterase |
| M. vanbaalenii PYR-1 | Mvan_5540 | - | 1e-28 | 34.88% (215) | thioesterase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2010|M.avium_104 --------------------------------MFPHAGAAAASYRVLAAA
TH_4495|M.thermoresistible__bu -----MTVLRQDFAPWIKRFPAGGERTGRAAVLFPHAGGAAAAYRTLAKA
MSMEG_4514|M.smegmatis_MC2_155 -----MTGTEVSLESWIKRYPAENTASG-PTLVFPHAGGAALAYRPFALA
MUL_3636|M.ulcerans_Agy99 --------MARKLG-WVRQFHEPDAPESLPLLVFPHAGAGASAYREFSKV
MAB_2033|M.abscessus_ATCC_1997 ---MRRTDELLPGNPWLRRLRDGNGATR--VICFPHAGGSASYFRRLAKM
Mb2953|M.bovis_AF2122/97 MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSRE
Rv2928|M.tuberculosis_H37Rv MLARHGPRYGGSVNGHSDDSSGDAKQAAPTLYIFPHAGGTAKDYVAFSRE
MLBr_02359|M.leprae_Br4923 MLHVLRPGYAGAVNGHSNNGNDDETSTTPTLYIFPHAGGDATYYVPFSRE
Mflv_1276|M.gilvum_PYR-GCK -------MTQPPRSRWLRNFHP-APSARTRLVCLPHAGGSASYYFPMSAA
Mvan_5540|M.vanbaalenii_PYR-1 -------MTQPQRSRWMRNFHP-SPTARIRLVCFPHAGGSASYYFPLSSA
MMAR_0367|M.marinum_M ------------------------MPPALRVYCVPHAIGSASLYGEWSDR
.*** . * : :
MAV_2010|M.avium_104 LAA-GADTYVVQYPQRAERLGDPAHESVHDLAVGLF---RAAPWPGVAPL
TH_4495|M.thermoresistible__bu LSDNGTDTYIVQYPQRAERLRHPAADSISDLAAQLF---EAGPWGSVGPL
MSMEG_4514|M.smegmatis_MC2_155 LAEAGSDAYVMQYPRRGDRLSHPAPATVGDLARDLF---EAGDWTRLGPL
MUL_3636|M.ulcerans_Agy99 LSE-TFNVIVFQYPGRQDRAAEPSCAAISEIAAGAFSEFAASEHNRGLPI
MAB_2033|M.abscessus_ATCC_1997 LPA-DTEVLAVQYPGRGNRLREQPIASVPLLAEGIA----SALPASDKQD
Mb2953|M.bovis_AF2122/97 FSA-DVKRIAVQYPGQHDRSGLPPLESIPTLADEIFAMMKPSARID-DPV
Rv2928|M.tuberculosis_H37Rv FSA-DVKRIAVQYPGQHDRSGLPPLESIPTLADEIFAMMKPSARID-DPV
MLBr_02359|M.leprae_Br4923 FSA-DIKRIAVHYPGQRDGYGLPALTSIPALADEIFAIMKPSAPPE-GAV
Mflv_1276|M.gilvum_PYR-GCK LSP-EFNVYGVQYPGRQDRHSEPFVESVDDLADQIY---AEVAALPEVPT
Mvan_5540|M.vanbaalenii_PYR-1 LTP-EFDVFGVQYPGRQDRYSEPFVETIDELADQAH---AALSALPDAPL
MMAR_0367|M.marinum_M LPS-WVRVVPLEYPGHGRRFGQPPLTAIDEIARVFAR---ELAADLDGPY
:. ..** : :: :*
MAV_2010|M.avium_104 TLFGHSMGGVVAFEFARVAE-ANGTPVRKLWVSAGPPPCVVGDMP----E
TH_4495|M.thermoresistible__bu DLFGHCMGAVVAFEFARVAE-RHAVPVGTLWASAGQAPSTVGEGP----P
MSMEG_4514|M.smegmatis_MC2_155 CLFGHCMGAVVAFEFARVAE-RNGVAVEALWVSASEAPSAVAASP----A
MUL_3636|M.ulcerans_Agy99 ITFGHSMGALVAFEFVRLAE-ANGIDVRHLNVSAAVAPCNAAAKP----A
MAB_2033|M.abscessus_ATCC_1997 VLFGHSLGGHIAFEVA------QRLPVRKLVVSGIVAPSKVVDLG----Y
Mb2953|M.bovis_AF2122/97 AFFGHSMGGMLAFEVALRYQ-SAGHRVLAFFVSACSAPGHIRYKQ----L
Rv2928|M.tuberculosis_H37Rv AFFGHSMGGMLAFEVALRYQ-SAGHRVLAFFVSACSAPGHIRYKQ----L
MLBr_02359|M.leprae_Br4923 AFFGHSMGGMLAFEVALRFQ-SAGYRLIALFVSACSAPGYIRYKQ----I
Mflv_1276|M.gilvum_PYR-GCK AFFGHSMGAVLAFEVARRFESLAGRRPVVVFASGSRAPSHYGDER----E
Mvan_5540|M.vanbaalenii_PYR-1 AFFGHSMGAVLAFEVARRCETLSGRQVVTVFASGSRAPSRYGDER----N
MMAR_0367|M.marinum_M ALFGHSMGALVTFELARELRQQRAPLPVKLYAAASRPPVVFWPPNRGQYL
***.:*. ::**.. . .:. .*
MAV_2010|M.avium_104 LPTTHDGLLADIADLGGTDPELLADEEFSELLTTAVRADYQAFNGYDPSP
TH_4495|M.thermoresistible__bu LPTTDADVLADMVDLGGTDPRLLDDEDFVELLVMAVRADYRALSGYRCGP
MSMEG_4514|M.smegmatis_MC2_155 LPMGESEIIAEMVDLGGTDPQLLADDDFVELLLTAVRADYEAFNRYSCDQ
MUL_3636|M.ulcerans_Agy99 HPSDDEEILNHLGALEGTDTDVFSNRELMRLALRVIKADYHAFDTYSCAE
MAB_2033|M.abscessus_ATCC_1997 RLLNEAEGIERIAALGGLPPEILDDPSALSALFPVLRSDFTAGETYTPPP
Mb2953|M.bovis_AF2122/97 QDLSDREMLDLFTRMTGMNPDFFTDDEFFVGALPTLRAVR-AIAGYSCPP
Rv2928|M.tuberculosis_H37Rv QDLSDREMLDLFTRMTGMNPDFFTDDEFFVGALPTLRAVR-AIAGYSCPP
MLBr_02359|M.leprae_Br4923 KDFSDNDMLDLVVRMTGMNPDFFEDEEFRVGVLPTLRAAR-IIAGYNCPP
Mflv_1276|M.gilvum_PYR-GCK YK-SDNDLIGVMRDLGGTDPRIFNDPDLLSTFLPAFRNDYRALQAYHRGT
Mvan_5540|M.vanbaalenii_PYR-1 AK-SDTDLVGVMRELGGTDPRVLENPELLATFLPAFRNDYRALQAYHRGT
MMAR_0367|M.marinum_M SALSDSALLSRLNSFGGTPSELLHNAELMDLMLPIARADLTACEEYLYRP
. : . : * . .: : . : *
MAV_2010|M.avium_104 DVRIGADIHVLGGHHDHRIATGVLRQWERHTAGSFAMSLYDGG-HFYLYD
TH_4495|M.thermoresistible__bu DERIRADIHALRGDRDHRISREWSDRWASHTSGRFTLSTFDGG-HFYLND
MSMEG_4514|M.smegmatis_MC2_155 GVTIAADIHALGGEQDHRISEDMLRGWQIHTEGAFTLSMFDGG-HFYIND
MUL_3636|M.ulcerans_Agy99 DIKVATPIHAMGGDQDPYITLGDLYGWGKHTD-TAKVTMFDGG-HFYLRS
MAB_2033|M.abscessus_ATCC_1997 DATVACDITALIGDKDVLAPLERVSSWREHTRANFDLQVFRGGGHFYLED
Mb2953|M.bovis_AF2122/97 ETKLSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGD-HFYLND
Rv2928|M.tuberculosis_H37Rv ETKLSCPIYAFIGDKDWIATQDDMDPWRDRTTEEFSIRVFPGD-HFYLND
MLBr_02359|M.leprae_Br4923 ETTVSCPIYTYIGDKDWIATQEDMKPWRERTTGAFAIRVFPGD-HFYLNG
Mflv_1276|M.gilvum_PYR-GCK EVVISAPIVVMTATDDPKTSEDNARAWLAHTTGGGEVRTFTGG-HFYLEK
Mvan_5540|M.vanbaalenii_PYR-1 DIGISAPIVVMTATDDPKTSETDARAWHEHTSGGGEVHTFTGG-HFYLEK
MMAR_0367|M.marinum_M APPLSCPITALGGVGDVTFDQSELTRWGEMTSATFEVVAMPGG-HFFVRT
: * . . * * * : *. **::
MAV_2010|M.avium_104 HVETVAAQVNAG--------
TH_4495|M.thermoresistible__bu HLTDVAALVSGR--------
MSMEG_4514|M.smegmatis_MC2_155 YTDDVAELVNELW-------
MUL_3636|M.ulcerans_Agy99 HIDAVAALLASSAQCGQQA-
MAB_2033|M.abscessus_ATCC_1997 HIDEVSACLIQVCNVSPII-
Mb2953|M.bovis_AF2122/97 NLPELVSDIEDKTLQWHDRA
Rv2928|M.tuberculosis_H37Rv NLPELVSDIEDKTLQWHDRA
MLBr_02359|M.leprae_Br4923 NLSELVCDIEDKTLEWCDRA
Mflv_1276|M.gilvum_PYR-GCK QPQKVIEVVTQTLRDVG---
Mvan_5540|M.vanbaalenii_PYR-1 QPQRVIEVVSATLRSVG---
MMAR_0367|M.marinum_M AAALLSWLAEDFRRVLGFSR
: