For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TAPEIGCAEAIPLSKSQQNLYNGVLQDNDPALYLIGKRYRFHPLALSNFLAALEASVLNNPVQLCVLQMA ATDADYPQLVPRLQFSDLVLVRSAAQGQPDGPGADLEHTWSSGILDRPLVRYTVSTDEGGNVCGLDVHTH HILLDGGATGIIEADLAHFLAASLEPAGVGQMPTLSQGLAKLAAAHLRETAKVAEALRRQADAVQRELTA EAGQGGGAQGASGTSGAAAKGVLQESIALCGPAYDALRALSEAQQVPLNVLVAAAAVAVQAGLRQSTESL LVHAVDNRFGDPELNVATCLVNSVAHALRFRPFASVREVVRDLDRGYVKAVRRRWIREEHYRRMYLAINR TSHVQALTLNFIRESCAPGLRPFLSEAPVATEIGPIEGTTVACVLDEQRHTLNLAIWDRADLPERNTGAG VAARIGAALESMAALWDQPIAMTANEWFEVGADGLPCRTEAAGRPRPPSAPAWFVDAAPGLRQFLDRRRH VYPWVGWLVCHGVVPGDVLVCTDDDTDKTVDLLLACHLAGCGYSMCESVDDLSLRATTIGEHCEGSSAHP VDVAAVRLGAVPDHALRERIDQRLDQVARDPLLATKAAYIMPTSGTTGQPKLVRISHGSLAAFCAAIGPS YGWNSRDTILQCAPLTSDISVEEIFGAAVCGAELVRSAAMKTGDLGGLARDIHALGPTVVDLPTAVWHLL CEDGDAVDVIGRSRLRQIVIGGESIRTSTVDKWVNSPVLAPISLVSSYGPTEATVVATHLPIVYDGIAAA AHTRLRVGLPMAPNTVFIAFGEVVIAGPLVSDGYLGIDDSSFGAVAPGDGSQLRAFATADRVTIDEEGFP VFAGRKDTIVKVAGKRVDTAAVARRISADPTVCDVAVEPHDGRLGVWFETERTREAAEDGATAGRIGLTL ASLGVPAFFVVAVPSIPRKPNGKVDGARLHTLPQLADAVPSDAEAGESAAGLARVWSRHLGRPLAADSSL LGAGIGSLDLIRILPDTRRYLGRHLSVLELISADTAANLVCDLGSNPAAPATDGWLDAETAAAIERDLVS LGSQCTPQPLGAKPPPHDRAAAPIVVLGASGIVGTGFARAVLERKQAGLACPEIVLASRSKPPEHGPWSA LRGLEGIRIEQLGATLGAADLDALICDTGARSLINCIGNTNVLVPYRGLRAANVELVSTVAQVCAQRDVR LVHLSTFVISADVTAPRVTDPRMSPYPYAASKSLAELIVAASSPALDFTIVRLPRVLGEDYQLRESADIL VSVVDACMALRAFPTLTLTEEVTTGRAAAQAILGLLPQFSGAAGLGHGITVVRGAAVQYRELLSGYALDE IDAAEWKHRLDQSDWARRNPQRWSVVDAWVSLGMRLGARSYSQYLAGYPSIPLQVGTVAEIAAPPTALRA LLEQGCAQPPRPALA*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_0256 | - | - | 100% (1416) | non-ribosomal peptide synthetase |
M. marinum M | MMAR_2766 | - | 9e-32 | 24.84% (946) | non-ribosomal peptide synthetase |
M. marinum M | MMAR_1250 | - | 9e-31 | 29.36% (453) | peptide synthetase Nrp (peptide synthase) |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0104 | nrp | 0.0 | 66.47% (1020) | peptide synthetase |
M. gilvum PYR-GCK | Mflv_2696 | - | 7e-29 | 28.00% (475) | amino acid adenylation domain-containing protein |
M. tuberculosis H37Rv | Rv0101 | nrp | 0.0 | 66.47% (1020) | peptide synthetase |
M. leprae Br4923 | MLBr_01996 | nrp | 0.0 | 61.99% (1410) | putative peptide synthase |
M. abscessus ATCC 19977 | MAB_0663 | - | 0.0 | 55.49% (1402) | cyclic synthetase (peptide synthase) |
M. avium 104 | MAV_3239 | - | 1e-28 | 27.97% (547) | syringomycin synthetase |
M. smegmatis MC2 155 | MSMEG_0402 | - | 3e-25 | 26.41% (515) | linear gramicidin synthetase subunit D |
M. thermoresistible (build 8) | TH_3141 | - | 1e-30 | 28.69% (474) | PUTATIVE amino acid adenylation domain |
M. ulcerans Agy99 | MUL_4858 | - | 0.0 | 97.81% (1416) | non-ribosomal peptide synthetase |
M. vanbaalenii PYR-1 | Mvan_3845 | - | 1e-28 | 27.99% (468) | amino acid adenylation domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 MLGVGRVGVEDSFFDLGGDSLSAMRLIAAVNGVLGAGVSVRTLFEAPTVA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 QLAPRVRGGGRTLARVVAGERPAVVPLSFAQSRLWFLDQLQGPSPMYNMA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 AALKLQGPLDVSVLRAALADVIARHESLRTVFAVSDGTPHQVVIPAEQAD MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 IGWDVVDTAGWSPARMKEAIDAAAGHAFDLSTEIPLRATLFRNSLDEHVL MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 VAVAHHIAADGSSLNPLLRDLTAAYTARCAGRVPDWVPLPVQYIDYALWQ MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 RAQFGDLEDPDSPIAGQLRYWQEALAGLPERLALPTDRPYPAVADHRGAR MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 VDIDWPASLQQQVSALARVHNATSFMVVQAGLAVLLAKLGASCDVAVGFP MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 IAGRGDPALDDLVGFFVNTLVLRVDLSGDPTVGEILARVRQRSLAAYEHQ MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 DVPFEILVERLNPTRSLAHHPLIQVMLTWRGDDPTRLRLGELEVAALPID MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 IGTARMDLTFSLCERWTEEGRPAGIAGTVEFRTDVFDADTIRTLTERLRR MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 VLDVLTADPGRHLSSIEVLEDTEFARLDIFGNRAALGRSTTGASVPALFG MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 AWAQRVPGAVAISSADRCWTYREVDETANRLAHLLIQHGVDRGQYVGLLL MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 DRSAEAVVAILGVLKAGAAYVPMDPAVPAARIAFIVADADLRVVVTDAGS MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 RSRLTGLGAAIVDLDDPALADYPATEPAGPGPAAGDIAHVIYTSGTTGEP MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 KGVAVSHRNITQLFASLDTGITLGPDQVWSQCHSLAFDFSVWEIWAALLH MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 GGRLVVVSDAVARSPDDLRRLLIRERVTVLTQTPSAAGALSPQGLDSVAL MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 VIGAEPCPPELVDRWAPDRVMINVYGPTETTMWVSHSRPLAAGSGAPPIG MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 SPVAGASFFVLDPWLCPAPVGVTGELYVAGAGVGAGYVGRAALTASRFVA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 CPFGGTGTRMYRTGDLVRWGADGQLHYVGRADEQVKIRGYRIELGEIRSA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 LTDLDGVEQAAVIAREDSPGHKRLVAYLTGTADPAQVRTQLADRLPGYML MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 PSAVLALDALPLTVNGKLDTRALPAPELRAENRYRAPQNPTEESLADVYA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 RLLGLERVGVDDSFFELGGDSLSAMRLITAVNAELDADLTVRALFEAPTV MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 AQLAPRVAAGTGRAGRLVAAERPAVLPLSFAQSRLWFIDQLHGPSPVYNM MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 AVALNLRGPLDTDALGAALGDVVARHESLRTLFPAPDGAPRQVVLEAERA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 EVDWQVVDAARWPASWLAEATHEAARYTFDLATEIPLRAWLFRRNHDEHV MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 LVAVVHHIAADGWSLTPLVRDLGAAYASRCRGRPPDWAPLPVQYADYTLW MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 QRAQFGDLDDPDSPIATQLQYWQRALAGMPERVALPTDRPYPLVADHLGA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 SVQVHWPAELQQHIAQLARTHNATSFMVVQAALAVLLSTLSANPDVAVGF MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 PIAGRRDPALDDVVGFFVNTLVLRVDLADDPSIAELLGQVRHRSLQAYEN MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 QDVPFELLVERLNPTRSLAHHPLVQVMLAWQNNDPVDVSLGDVHVTPMPL MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 ENQVARMDLVWSLAERWTADGRPDGIDGTVEFRTDVFDAASIETLVRRLQ MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 RVLLAMTADP-ARPVSSIDILDEPEYAHLDALGNRAALTRPATGWVSISQ MSMEG_0402|M.smegmatis_MC2_155 -----MTAEPSTRTLLSFDLLDEDEHDQIEVWGNRAVLTDPGPTPVTIPA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 LFAAQVARTPEAVAISCGERSWTYRELDSSANRLARVLAGRGARPGERVA MSMEG_0402|M.smegmatis_MC2_155 LFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 VLVPRSAGAVVSILAVLKTGAAYVPIDPGLPSARIDFMLADAVPVVTVTT MSMEG_0402|M.smegmatis_MC2_155 FLIPRSGEAILSILSVLKTGAAYLPVDPAHPDARIGFMMSDAKPVAALTT Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 AELRASAGDPD-RVVAIDDPAPHVPRIGGRAAPAPDDIAYVIYTSGTTGV MSMEG_0402|M.smegmatis_MC2_155 ADLRSRLDQYDLAVIDMADPAIDRRPSDALSGPRPDDLAYMTYTSGTTGV Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 PKGVAVTHHNVTQLLGSLDDRL--GLGRVWSQCHSLAFDFSVWEIFGALL MSMEG_0402|M.smegmatis_MC2_155 PKAVAVTHHNVTQLVSALHADLPSGPGQVWSQWHSLVFDVSVWEIWGALL Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 RGGRLVIVPDDVVRSPEDLHALLIGEGVTVLSQTPSAAAALSPERLESVA MSMEG_0402|M.smegmatis_MC2_155 HGGRLVVVPESVGSSPDDLHNLLITEKVSVLCQTPSAAGMLSPEGLESTT Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 LVLGGEACPVELMDRWAPGRLMVNQYGPTETTLYATMTTPLRAGGAAVPI MSMEG_0402|M.smegmatis_MC2_155 LIVAGEACPTELVDRWAPGRVMINAYGPTEATIYAAMSEPLTAGTGVAPI Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 GSPVPGAALFVLDGRLRRVPPGVVGELYVAGRGVAAGYLGRAALTASRFV MSMEG_0402|M.smegmatis_MC2_155 GAPVPGAALFVLDKWLRPAPEGVVGELYVAGHGVATGYIGRPDLTASRFV Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 ACPFGGTGTRMYRTGDLARWGADGQLHYVGRADEQVKIRGFRIELGEIRS MSMEG_0402|M.smegmatis_MC2_155 ACPFGETGERMYRTGDLVRWGSDGQLEYLGRADEQVKIRGYRIELGEIQA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 VLAGLDGVEQAAVIARDDGAGHPRLVAYITGTADPAELRAQLADRLPGYM MSMEG_0402|M.smegmatis_MC2_155 ALAKLDGVDQAVVIAREDRPGDKRLVGYITGTADPAQLRTALAESLPAYM Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 VPSAVVVLDALPLTGNGKLDTRALPAPDY--AGGRYRAPGDAIEEILAGI MSMEG_0402|M.smegmatis_MC2_155 VPTAVVVLDTIPLTVNGKLDRRALPAPEYRSAANDYRAPSTPAEQILADV Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGVMCTARDVFVEQT MSMEG_0402|M.smegmatis_MC2_155 YAQVLGVERVGVDDSFFDLGGDSILSMQVVARARAAGIQCRPRDIFVEQT Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 VARLARVVTVAAADGELGAADEGIGPVQPTPIMRWLQDIDGPIDEFNQTM MSMEG_0402|M.smegmatis_MC2_155 VAGVAR---VAVAAGESHVVDEGVGPVVATPIMRWLREVDGPTGQFNQTV Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 VLAAPAGVSQSDVAVVLQALLDRHPMLRLCLDD--DGAGGWDLHVPPPGS MSMEG_0402|M.smegmatis_MC2_155 ITQAPAGVTEDDVVVILQALLDRHATLRLRVEDTQEDTDEWSLLVPEAGA Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 VDARPILRTVDVLSEAALARARARLNPGAGLMLSAVWASETSQLALVVHH MSMEG_0402|M.smegmatis_MC2_155 VGARECLRTVDALTDDVLVEARNRLDPAAGAMVSAVWVRETSQLVLMIHH Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 LAVDGVSWRTLIEDINIAWAQHHSGQEIALPVPGTSFARWSSILAEYAKS MSMEG_0402|M.smegmatis_MC2_155 LAVDGVSWRILLEDLNIAWAQHCTGQSIELPAGGTSFARWSALLAEHAKT Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 PAVVAAAAAWQQVVATPAVLPAVGPD-DTYASAGQLSASLDVQTTRLLLG MSMEG_0402|M.smegmatis_MC2_155 DTVRDLADAWRAVTSVPQALPPVQPDTDTYVTAGQLSASLDVETTRQLLG Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 EVPAAFHAGVQDILLIAFGLACTEFVG-GGAPIGIDVEGHGRHEEIASGV MSMEG_0402|M.smegmatis_MC2_155 EVPAAFRAGVQDILLVAFGLAWTEFLNRSDTPIGVDVEGHGRYDELASDV Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 DLSRTVGWFTTKYPVALRMSRRLDWARVVAGEAALGAVIKDAKEQLRALP MSMEG_0402|M.smegmatis_MC2_155 DLSRTVGWFTTKYPVALTVEN-LPWEQVVAGDAALGGIVKAVKEQLRSLP Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M ------------------------------------------------MT MUL_4858|M.ulcerans_Agy99 ------------------------------------------------MT MLBr_01996|M.leprae_Br4923 ------------------------------------------------MT MAB_0663|M.abscessus_ATCC_1997 ------------------------------------------------MT TH_3141|M.thermoresistible__bu --------------------------------------------VTDTTE Mvan_3845|M.vanbaalenii_PYR-1 -----------------------------------------------MTD Mflv_2696|M.gilvum_PYR-GCK -----------------------------------------------MTD MAV_3239|M.avium_104 DGLSYGLLRYLNPEIEVQGPDPVIGFNYLGRLGGAAADLSDEHWRLSPDS MSMEG_0402|M.smegmatis_MC2_155 EGLTYGLLRYLNPEVDLGGSDPTIGFNYLGRLGAGAGELSEELWRIDQDS Mb0104|M.bovis_AF2122/97 ------MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLA Rv0101|M.tuberculosis_H37Rv ------MHRVRLSRSQRNLYNGVRQDNNPALYLIGKSYRFRRLELARFLA MMAR_0256|M.marinum_M APEIGCAEAIPLSKSQQNLYNGVLQDNDPALYLIGKRYRFHPLALSNFLA MUL_4858|M.ulcerans_Agy99 APEIGCAEAIPLSKSQQNLYNGVLQDNDPALYLIGKRYRFHPLALSNFLV MLBr_01996|M.leprae_Br4923 APNTRRVDRVPLSRSQQNIYNGMLQDNDPALYFIGKSYRFHQLELSVFLA MAB_0663|M.abscessus_ATCC_1997 VVLEPQVDRVPMSRSQQNMYNGAVQASDPGLYLIGKSFRFHPIELAAFMC TH_3141|M.thermoresistible__bu TRPAGADDEARLALLRRRLSERGLS----AQQTTGAAS--EDRLSDGQL- Mvan_3845|M.vanbaalenii_PYR-1 IDTGALLDERRLELLRRRMQERGLS----AGTDTAEPAGDTDVLTEGQL- Mflv_2696|M.gilvum_PYR-GCK TD----LDARRLELLRRRLAGSGLREQDPAEPVAVAADPARGEFTDGQK- MAV_3239|M.avium_104 PSVSAAAAAIPLPLGHTVELNAGTMDTDAGPQLHANWTWARSVLTDEQLN MSMEG_0402|M.smegmatis_MC2_155 LALSDAASAVPMPLMHTVELNAGTIDTDNGPSLRASWTWAPSAFDEEQAT : : . Mb0104|M.bovis_AF2122/97 ALHATVLDNPVQLCVLEN-------------------------------- Rv0101|M.tuberculosis_H37Rv ALHATVLDNPVQLCVLEN-------------------------------- MMAR_0256|M.marinum_M ALEASVLNNPVQLCVLQMA------------------------------- MUL_4858|M.ulcerans_Agy99 ALEASVLNNPVQLCVLQMA------------------------------- MLBr_01996|M.leprae_Br4923 ALEATILKNPGQLCVLEAP------------------------------- MAB_0663|M.abscessus_ATCC_1997 ALEAAVAANPVQLCVLEPG------------------------------- TH_3141|M.thermoresistible__bu ---RMWFVHQADPSGALLN------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 ---RMWFVHNADPSGALLN------------------------------- Mflv_2696|M.gilvum_PYR-GCK ---RMWFVHSVDPSGVLLN------------------------------- MAV_3239|M.avium_104 RLSRLWFEALTGICAHVQAGGGGLTPSDIAPTRLDQGRIEQLERRYDVAD MSMEG_0402|M.smegmatis_MC2_155 RLSRLWFEALAGICAHVRGGGGGLTPSDVAPARLTQRQIDELSQRYDVTD . Mb0104|M.bovis_AF2122/97 -----------------------------SGADYPDLVPRLRFGDIVRVG Rv0101|M.tuberculosis_H37Rv -----------------------------SGADYPDLVPRLRFGDIVRVG MMAR_0256|M.marinum_M ----------------------------ATDADYPQLVPRLQFSDLVLVR MUL_4858|M.ulcerans_Agy99 ----------------------------ATGADYPQLVPRLQFSDLVLVR MLBr_01996|M.leprae_Br4923 ----------------------------STEGDYPDLVPRLQFGDIVRVR MAB_0663|M.abscessus_ATCC_1997 ----------------------------VQHDRHPELVQRLQFGDIVSIA TH_3141|M.thermoresistible__bu ---------------------------ICLSYRISGPVDLAALRGALDAV Mvan_3845|M.vanbaalenii_PYR-1 ---------------------------VCLSYRLSGEIDVARLHDAVGAV Mflv_2696|M.gilvum_PYR-GCK ---------------------------VCLSYRISGEVDLARLHDAVTAV MAV_3239|M.avium_104 ILPLTPLQQGLLFHATGSHAEG-DVYAVQLSVTLRGALDPHRLHRALHTV MSMEG_0402|M.smegmatis_MC2_155 VLPLTPVQQGLLFHSTFARGIGDDVYAVQLDITITGVLDQHRLRDAVHTV : : : Mb0104|M.bovis_AF2122/97 SADEH--------------LQSTWCSGILGKPLVRHTVHTD--------- Rv0101|M.tuberculosis_H37Rv SADEH--------------LQSTWCSGILGKPLVRHTVHTD--------- MMAR_0256|M.marinum_M SAAQGQPDGPG------ADLEHTWSSGILDRPLVRYTVSTD--------- MUL_4858|M.ulcerans_Agy99 SAAQGQPDGPG------ADLEHTWSSGILDRPLLRYTVSTD--------- MLBr_01996|M.leprae_Br4923 SDEQPQTDSRD------YDLMHAWSPDILAKPLVRYTVRTD--------- MAB_0663|M.abscessus_ATCC_1997 ADEEGLTARTA------DAVASQWAADLKARPLVRYTVRTG--------- TH_3141|M.thermoresistible__bu ARRHPVLRTTY-----AADENGEPRPTVHAELRPGWTEHDLTDLADQSEQ Mvan_3845|M.vanbaalenii_PYR-1 ARRHRVLRTTYRTESTAAGDSGMPVPTVHTGLMPGWAEHDLSELS---ER Mflv_2696|M.gilvum_PYR-GCK ARRHPVLRTTF-----AADEAGEPQRTVHDDLLPGWTVQDISELS---EH MAV_3239|M.avium_104 VTRHPNLAARF------CPELGEPVQIIPAEPEIAWRYLELDASDV---- MSMEG_0402|M.smegmatis_MC2_155 VARHPNLAARF------VEQFGEPVQVLTADPMIAWRYLDLRGDDLT--- . : Mb0104|M.bovis_AF2122/97 -PNGYVTGLDVHTHHILLDGGATGTIEADLARYLTTDPAG----ETPSVG Rv0101|M.tuberculosis_H37Rv -PNGYVTGLDVHTHHILLDGGATGTIEADLARYLTTDPAG----ETPSVG MMAR_0256|M.marinum_M -EGGNVCGLDVHTHHILLDGGATGIIEADLAHFLAASLEPAGVGQMPTLS MUL_4858|M.ulcerans_Agy99 -EGGNVCGLDVHTHHILLDGGATGIIEADLAHFLAASLEPAGVGEMPTLS MLBr_01996|M.leprae_Br4923 -KNGFVARLDVFTHHILVDGGAIRIIEENLAHHLDTDNR----LEIPCIR MAB_0663|M.abscessus_ATCC_1997 -ADGRVRGLDIHAHHLLLDGGAIGVIEADLGRNLSSAKE----AKVSRTT TH_3141|M.thermoresistible__bu ARRLRLEVLAQREFTAPFDLSVDSPLRITMIRTGADEHIMLLVAHHIAWD Mvan_3845|M.vanbaalenii_PYR-1 ARGLRLEVLAQREFGRPFDLGAESPLRITVIRTAPAEYVMLLVAHHIAWD Mflv_2696|M.gilvum_PYR-GCK ARRLRLEVLAQREFGTPFDLATESPLRITVARTAPAEYIMLLVVHHIAWD MAV_3239|M.avium_104 --DEQLEQLSADERAAVRELGDRPPFGAALIRTADTEHRFVLTVHHLVMD MSMEG_0402|M.smegmatis_MC2_155 -PDHEIEQLCAAERSAVCDLLERPTFRAALIRTSGNQHRFVLTFHHIVID : * : : : : . Mb0104|M.bovis_AF2122/97 AG-----LAKLREAHRRETAKVEESRG-----------RLSAVVQRELAD Rv0101|M.tuberculosis_H37Rv AG-----LAKLREAHRRETAKVEESRG-----------RLSAVVQRELAD MMAR_0256|M.marinum_M QG-----LAKLAAAHLRETAKVAEALR-----------RQADAVQRELTA MUL_4858|M.ulcerans_Agy99 QG-----LAKLAAAHLRETTKVAEALR-----------RQADAVQRELTA MLBr_01996|M.leprae_Br4923 QA-----LDKLAEAHRREATKVEESLQ-----------RLANVVQRELAD MAB_0663|M.abscessus_ATCC_1997 GA-----LTRIATAHSREIAKADESLQ-----------RFGAAIQRELTD TH_3141|M.thermoresistible__bu DGSWEVFFDDLTRAYTGVDLGEELAP---QLPPGPRDPDADLAYWREVLA Mvan_3845|M.vanbaalenii_PYR-1 DASWEVFFDDLTGAYVGEKLRPARRP---VVAAGGSD-EDDVAYWRAVMA Mflv_2696|M.gilvum_PYR-GCK DGCWRVFFADLTRAYTGAELGPTPAP---VVEPPTSD--EDLRFWRSAMT MAV_3239|M.avium_104 GWSLPVLLQEIFACYYGARLPAPAPYRGFVTWLAARDVPAARAAWRAVLD MSMEG_0402|M.smegmatis_MC2_155 GWSLPILLQEIFAGYFGHRLPAAAPYRNFVNWLATQDATAAKAAWREVLD : : : * Mb0104|M.bovis_AF2122/97 EAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNV Rv0101|M.tuberculosis_H37Rv EAYHGGHGHSVSDAPGTAAKGVLHESATICGNAFDAILTLSEAQRVPLNV MMAR_0256|M.marinum_M EAGQGGGAQGASGTSGAAAKGVLQESIALCGPAYDALRALSEAQQVPLNV MUL_4858|M.ulcerans_Agy99 EAGQGGGAQGASGTSGAAAKGVLQESIALCGPAYDALRALSEAQQVPLNV MLBr_01996|M.leprae_Br4923 EVRNGGYGQVSNDAPGNAARGVLHESMIICGKAFDNIIALSETKQVPLNI MAB_0663|M.abscessus_ATCC_1997 AARRSVPGQHCDGAASGAAKGVLLESVTVSAKAFDAITALAEREQVPLNI TH_3141|M.thermoresistible__bu DPPEPLELPGPHGSAVPSGWRSARDSVTLGADTARRVVELAQETGCTPYA Mvan_3845|M.vanbaalenii_PYR-1 DPPEPLELPGPTGSAVPTSWRSQRTTLRLDGETARRVTALADEVGATPYA Mflv_2696|M.gilvum_PYR-GCK DLPEPLELPGPHGSAVPTTWRCRRVTATLSADTVERVRVAAREAGATPYM MAV_3239|M.avium_104 G-FDTPTLVAPRGADAPGRR--GVASFRMAAETTSAVSELARRRRTTVNT MSMEG_0402|M.smegmatis_MC2_155 G-FETPTLVAPPG--VPGPR--GIESYRVSAETTRALGELARSQHTTINT . : : . : : : . Mb0104|M.bovis_AF2122/97 LVAAAAVAVDASLRQNTETLLVHTVDNR--FGDSDLNVATCLVNSVAQTV Rv0101|M.tuberculosis_H37Rv LVAAAAVAVDASLRQNTETLLVHTVDNR--FGDSDLNVATCLVNSVAQTV MMAR_0256|M.marinum_M LVAAAAVAVQAGLRQSTESLLVHAVDNR--FGDPELNVATCLVNSVAHAL MUL_4858|M.ulcerans_Agy99 LVAAAAVAVQAGLWQSTESLLVHAVDNR--FGDPELNVATCLVNSVAHAL MLBr_01996|M.leprae_Br4923 LVATAAVAVDASLRQSTEGLLVHAVDNR--FGDPYLDVATCLVNSVAHSI MAB_0663|M.abscessus_ATCC_1997 LVAAAAVAVDASLRQSTQTLLIHAVDNR--FGEPDLEVATCLVNSIAHPV TH_3141|M.thermoresistible__bu VLLAVFGTLIFRYTHADDFLVATPVLNR---DSGAEQRIGYYGNTVAMRL Mvan_3845|M.vanbaalenii_PYR-1 VLLAVFGVLIHRYSHVDDFLVATPVLNR---NGDTDDVIGYFGNTVAMRL Mflv_2696|M.gilvum_PYR-GCK VMLAAFGALLHRYTHADDVLIASPVLLR---GPDSEDVIGYHGNSAVMRL MAV_3239|M.avium_104 VLQAAWAQLLMMLTGQHDVAFGTAVSGRPAELPGAESMVGLLINTVPVRA MSMEG_0402|M.smegmatis_MC2_155 VLQAAWTQLLMRMTGQRDVAFGTAVSGRPADLAGAESMVGLLINTVPIRA :: :. : : . .* * . *: Mb0104|M.bovis_AF2122/97 RFPPFASVSDVVRTLDRGYVKAVRRRWLREEH-YRRMYLAINRTSHVEAL Rv0101|M.tuberculosis_H37Rv RFPPFASVSDVVRTLDRGYVKAVRRRWLREEH-YRRMYLAINRTSHVEAL MMAR_0256|M.marinum_M RFRPFASVREVVRDLDRGYVKAVRRRWIREEH-YRRMYLAINRTSHVQAL MUL_4858|M.ulcerans_Agy99 RFRPFASVREVVRDLDRGYVKAVRRRWIREEH-YRRMYLAINRTSHVQAL MLBr_01996|M.leprae_Br4923 RFPPFASVQDVVRTLDRSYVKAIRLRWLREEY-YRRIYLALNQTSHIEAL MAB_0663|M.abscessus_ATCC_1997 SFPAFASVREVVRSLDRDYVKASRRRWLREEQ-YRRMYLAINKTAQVEAL TH_3141|M.thermoresistible__bu RPNAAMSFRDMLAQSRDTALGAFAHQGINLDRVVRELNPDRRHGTERMTR Mvan_3845|M.vanbaalenii_PYR-1 RPHPAMTFRDLLTQTRDTALGAFAHQRVGLDRMVRELNPDRRHGAERMTR Mflv_2696|M.gilvum_PYR-GCK RPQPMQTFTELLSRTRDFALDAFAHQQVNLDRVVRELNLDRRHGAERMTR MAV_3239|M.avium_104 RAAAATTIADLLDQLQCAHNDTVEHQHLGLN----EIHRVTGQDQLFDTL MSMEG_0402|M.smegmatis_MC2_155 KVSADTTVGDLLRQLQSHHNDTLEHEHLALN----DIHHVSGHEQLFDTL . :. ::: : . : : : : : Mb0104|M.bovis_AF2122/97 TLNFIREPCAPGLRPFLSEVPIATDIGPVEGMTVASVLDEEQR----TLN Rv0101|M.tuberculosis_H37Rv TLNFIREPCAPGLRPFLSEVPIATDIGPVEGMTVASVLDEEQR----TLN MMAR_0256|M.marinum_M TLNFIRESCAPGLRPFLSEAPVATEIGPIEGTTVACVLDEQRH----TLN MUL_4858|M.ulcerans_Agy99 TLNFIRESCAPGLRPFLSEAPVATEIGPIEGTTVACVLDEQRH----TLN MLBr_01996|M.leprae_Br4923 TLNFIREPCAPGLRPFLSEVPTVTDIGPVEGMTVACVLNEDER----TLD MAB_0663|M.abscessus_ATCC_1997 TFNFIRETCAPALRPFLSAAPRVTDIGPVEGMTVSCVADEDRR----TLT TH_3141|M.thermoresistible__bu VSFGFRGPDRFGFTPPGVRCERAELRSHLTQLPLGVMIEFDPDPADPGAT Mvan_3845|M.vanbaalenii_PYR-1 VSFGFRSRDRFGFTPPGVTCERADLRSHLTHLPLGIMVEFDPD----EVV Mflv_2696|M.gilvum_PYR-GCK VSFGFREPDGGGFSPPGVTCRRAELRGQITQLPLGLMVELHES----GAV MAV_3239|M.avium_104 LVYENYPIDTAALSAADDLTATEFSCHDYNHYPLSLQVVPGDE-----LG MSMEG_0402|M.smegmatis_MC2_155 FLYESYPIDTSAFMGVQELAVTEFNNREYNHYPLSVMALPGHE-----LG .: .:. Mb0104|M.bovis_AF2122/97 LAIWNRADLPACKTHPKVAERIAAALESMAAMWD---------------- Rv0101|M.tuberculosis_H37Rv LAIWNRADLPACKTHPKVAERIAAALESMAAMWD---------------- MMAR_0256|M.marinum_M LAIWDRADLPERNTGAGVAARIGAALESMAALWD---------------- MUL_4858|M.ulcerans_Agy99 LAIWDRADLPERNTGAGVAARIGAALESMAALWD---------------- MLBr_01996|M.leprae_Br4923 LSIWNRVDLPQGKSCTRVAKRIAAALELMAAAWD---------------- MAB_0663|M.abscessus_ATCC_1997 LSIWHRSDLPKASAHPWVAERIAGALSSMEAMWH---------------- TH_3141|M.thermoresistible__bu VEIEHLVEVIEPALGRQLLRHFVVLLEDALRRP----------------- Mvan_3845|M.vanbaalenii_PYR-1 VELEHLVEIIEPGLARQLLDHYAVLIRSALDDP----------------- Mflv_2696|M.gilvum_PYR-GCK VEAEFLVEVLDDTLVTQMLDHYVVLLEAAVAQP----------------- MAV_3239|M.avium_104 LRLEFDTDVFDPAAIDTLADRLRRLLAAMPADPDRPLRSLDLLDSTEHTR MSMEG_0402|M.smegmatis_MC2_155 LRVEYDTSVFDVSEIETLIDRFQRLLEAMIDDP----------------- : .: : : : Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 LQRWGNRPALSRPATGPSLPELFTAQVANAPHAVALRCAGRSMTYRELDE MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 ASTRLAHLLAGHGATPGCFVALLFSRSAEAIVAMLAVLKTGAAYLPIDPA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 LPATRIEFMLGDAAPVVAVSTAGLRARLEAFGLPVVDVAATGAQPGGPLP MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 PPAPDNIAYLLYTSGTTGVPKGVAVTHRNVAQLLESLHASLPGTGVWSQC MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 HSYGFDVSVQEIWGALAGGGRLVVVPESVTSSPDELHALLIAENVTVLSQ MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 TPSALAALSPRNLHAALVIGGEPCPAALADRWAPGRVMINAYGPTETTVD MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 AVLSTPLAAGAGAPPLGSPVAGATLFVLDGWLRPVPAGVTGELYIAGAGV MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 AAGYLGRAGLTAARFVACPFGGAGARMYRTGDLVRWDRDGRLHYVARADQ MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 QVKIRGHRIELGEIHSALAELDGVEQAAVIAREDRPGEKRIVGYLTGTAD MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 PAAIRARLAERLPAYMVPAAVLAIEALPLTPNGKLDARALPAPEYAGGAY MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 RAPSTPTEEIIAGIYTQVLGLHRVGVDDSFFDLGGDSLSAMRVIAAVNAG MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 LDARLSVRVLFEAPTIAQLAARLGEGGHRFAAVVAAERPAVVPLSFAQSR MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 LWFIGQLHGPSPVYNMVAALRLHGPVDIGALGAALHDVVTRHESLRTVFA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 ATDGTPAQVVLPPDRADIGWQVIDASGWSPARVDDVIRDTARHTFDLAAE MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 IPLRAVLLRCGDEEHLLVAVVHHIAADGWSLTPLVRDLARAYASRSAGRV MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 PDWVPLPVQYVDYTLWQRAQFGDLDDPHSLIAGQLRYWESALAGMPERLE MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 LPTDRPYPVVADFRGASVAVEWPAQLQQQISRLAGAHNATSFMVVQAALA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 VLLAKVSASSDVAVGFPIAGRRDPALDDVVGFFVNTLVLRVDVSGDPTVA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 ELLARVRQRSLAAYEHQDVPFEVLVERLNPARSLAHHPLVQVMLAWQNIE MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 PTELSLGQVRVIPLPVDTRTARMDLAWSLAERWTPDGSPAGIGGAVEFRT MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 DVFDTATVEALTQRLRRVLAAMTADPGRRLSSIDLLDPDEHARLDALGNR MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 AALTRPQHPPTSIPAMFAAQVARTPHAVALTANGRSVTYRRLEEHANQLA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 HQLIRYGAGPGRCVAVLLERSAEAVAAILGVLKAGAAYLPIDPSLPSARI MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 EFMLTDAAPAAVLTSTEFHCRLQEYDQTVIDVDDPSIREQPVTAPPAPAP MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 DNIAYLIYTSGTTGVPKGVAVTHRNATQLFASLGAAGLPAAPGKVWGQCH MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 SLAFDFSVWEIFGALLNGGRVLVVPDDVVRSPEDLCALLIDEHVDVLSQT MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 PSAFDALQRADSARRLNPQTVIFGGEALIPHRLGGWLDGHPARPRLINMY MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 GITETTVHASFREIVDGDIDGNVSPIGMPLAHLGFFVLDGWLRPVPAGVT MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 GELYIAGAGVAAGYLGRPGLTASRFVACPFGGAGERMYRTGDLARWGTDG MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 QLHYLGRADQQVKIRGYRIELGEIQSALAELDGVEQATVIAREDRPGDKR MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 LVGYVTGTADPAQLRTALAERLPAYLVPAAVVAIDAMPLTPNGKLDTGAL MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 PAPDYHGADQYHAPASAVEQTLADIYAHVLDVRPPRLVGIDDSFFDLGGD MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 SLSAMRLVAEVNSRLDVHLGVRALFEAPTIRRLAARLGADGSARAPLVAA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 ERPAVVPLSFAQSRLWFIGQLHGPSPVHNMAIALQLHGRLDAAAFGAALA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 DVVGRHESLRTLFPAHEGIPQQLVIEVDEADIGWQVIDASGWSPARLDDV MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 IRDTARHTFDLAAEIPLRAVLLRCGDEEHLLVAVVHHIAADGWSLTPLVR MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 DLARAYASRSAGRVPDWVPLPVQYVDYTLWQRAQFGDLDDPHSLIAGQLR MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 YWESALAGMPERLELPTDRPYPVVADFRGASVAVEWPAQLQQQISRLAGA MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 HNATSFMVVQAALAVLLAKVSASSDVAVGFPIAGRRDPALDDVVGFFVNT MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 LVLRVDVSGDPTVAELLARVRQRSLAAYEHQDVPFEVLVERLNPARSLAH MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 HPLVQVMLAWQNIEPTELSLGQVRVIPLPVDTRTARMDLAWSLAERWTPD MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 -------------------------------------------------- Rv0101|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu ----------------------------------------DTPLSRLRLM Mvan_3845|M.vanbaalenii_PYR-1 ----------------------------------------DTTLSGLQLM Mflv_2696|M.gilvum_PYR-GCK ----------------------------------------DTVLSRLELM MAV_3239|M.avium_104 GSPAGIGGAVEFRTDVFDTATVEALTQRLRRVLAAMTADPGRRLSSIDLL MSMEG_0402|M.smegmatis_MC2_155 ----------------------------------------ARRLSSMDVV Mb0104|M.bovis_AF2122/97 ------RPIAMIVNDWFGIGPDGTRCQGD--WPARQPSTPAWFLDSARGV Rv0101|M.tuberculosis_H37Rv ------RPIAMIVNDWFGIGPDGTRCQGD--WPARQPSTPAWFLDSARGV MMAR_0256|M.marinum_M ------QPIAMTANEWFEVGADGLPCRTEAAGRPRPPSAPAWFVDAAPGL MUL_4858|M.ulcerans_Agy99 ------QPIAMTANEWFEVGADGLPCRTETAGRPRPPSAPAWFVDAAPGL MLBr_01996|M.leprae_Br4923 ------QPIAMIVNEWFGISSDGALCLGNEVTQTTRPLAPAWFLDPGGSV MAB_0663|M.abscessus_ATCC_1997 ------MPIAMTVNEWFGIGADGARRRGDDHAPAESTALPAWFVDSEDAV TH_3141|M.thermoresistible__bu DDADLAWLRDVSRGDRFDTPA---RTLPDLIESQVRQTPDAVAVVYEGRH Mvan_3845|M.vanbaalenii_PYR-1 GDDDLEWLRAVSVGPTFDTPP---ATITDLIEAQVRRSPDGTAVVYEGRH Mflv_2696|M.gilvum_PYR-GCK DGDDAEWLRRVSHGPEFDVPA---ATIGELIEARTDLTPDTVAVVYEGRR MAV_3239|M.avium_104 DPAEHARLDALGNRAVLTRPQHPPTSIPEVFAAHVARTPHAVAVTCGRRS MSMEG_0402|M.smegmatis_MC2_155 DDDERTQLDEWANRAVLTQPVDSPQSIPEVFARQVERDPEAPAVTFEGES : : : Mb0104|M.bovis_AF2122/97 HQFLGRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGC Rv0101|M.tuberculosis_H37Rv HQFLGRRRFVYPWVAWLVQRGAAPGDVLVFTDDDTDKTIDLLIACHLAGC MMAR_0256|M.marinum_M RQFLDRRRHVYPWVGWLVCHGVVPGDVLVCTDDDTDKTVDLLLACHLAGC MUL_4858|M.ulcerans_Agy99 RQFLDRRRQVYPWVGWLVCHGVAPGDVLVCADDNTDKTVDLLLACHLAGC MLBr_01996|M.leprae_Br4923 HLTVDKRRYVHPWIAWLVRGSVVPGDVLVFTDDNTDKTIDLLIACHLAGC MAB_0663|M.abscessus_ATCC_1997 AEFLQRRRFVEPWIGWLIAAGVSPGDIVVCADDDSDKAIDLLIACHLAGC TH_3141|M.thermoresistible__bu YSYRELNEAANRVAHWLIGQGIGTEDRVAVLLDKSPELVITALGVLKAGA Mvan_3845|M.vanbaalenii_PYR-1 YTYREINEAANRVAHWLIGEDVGAEDRVAVMLDKSPELVVTALGVLKAGA Mflv_2696|M.gilvum_PYR-GCK YTYREINESANRVAHWLIGQGIGAEDRVAVLMDRSPELLITALGIIKAGA MAV_3239|M.avium_104 WTYRELDSSANRLAHLLIHHGAGPGDCVALLLERSAEAVAAILGVLKAGA MSMEG_0402|M.smegmatis_MC2_155 LNYGELDEAANQLANLLAVYGAAPGKSVALMVPRSADAIVAILAVLKTGA . * . . . :. : . : :. :*. Mb0104|M.bovis_AF2122/97 GYSVCDTADEISVRTNAITEHGDGILVTVVD--VAATQLAVVGHDELRKV Rv0101|M.tuberculosis_H37Rv GYSVCDTADEISVRTNAITEHGDGILVTVVD--VAATQLAVVGHDELRKV MMAR_0256|M.marinum_M GYSMCESVDDLSLRATTIGEHCEGSSAHPVD--VAAVRLGAVPDHALRER MUL_4858|M.ulcerans_Agy99 GYSMCESVDDLSLRAKTIGEHCEGISAHPVD--VAAVRLGAVPDHALQER MLBr_01996|M.leprae_Br4923 GYSVCDTVAEVPLRAKAITDHGGGVSARVID--VAATQLAVTPDNEQSKL MAB_0663|M.abscessus_ATCC_1997 GYSVCENSEGLVARSDSIAMQGDDITVHAVD--IAVT-IPTELDASMRGR TH_3141|M.thermoresistible__bu VYLPIDPTYPDDRLSFILGDCDARLVLR------------EPVSDLDGQP Mvan_3845|M.vanbaalenii_PYR-1 VYVPIDPAYPQDRLEFILGDCDAKVVVR------------EPVTGLDGYR Mflv_2696|M.gilvum_PYR-GCK VYLPVDPSYPQDRMSFVLSDSDPTLVIR------------EPVAGLDGHR MAV_3239|M.avium_104 AYLPIDPSLPSARIEFMLTDAAPAAVLTSTEFHCRLQEYDQTVIDVDDPS MSMEG_0402|M.smegmatis_MC2_155 AYLPIDPSVPAARLEFMLGDAKPVAAVTTGDLRSRFDGFDLQVVEVDDPA * : : Mb0104|M.bovis_AF2122/97 VDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAI-S Rv0101|M.tuberculosis_H37Rv VDERVTQVTHDALLATKTAYIMPTSGTTGQPKLVRISHGSLAVFCDAI-S MMAR_0256|M.marinum_M IDQRLDQVARDPLLATKAAYIMPTSGTTGQPKLVRISHGSLAAFCAAI-G MUL_4858|M.ulcerans_Agy99 IGQRLDQVARDPLLATKAAYIMPTSGTTGQPKLVRISHGSLAAFCAAI-G MLBr_01996|M.leprae_Br4923 ADKLIKQAAQDISLADKTAYIMPTSGSTGQPKLVQVSHGSLALFCDAV-R MAB_0663|M.abscessus_ATCC_1997 VAERREQVAKDGALAEKTAYIMATSGSTGRPKLVPISHGALALFVRAA-G TH_3141|M.thermoresistible__bu TTDPTDTDRVRRLLPGNTAYLIYTSGTTGLPKGVPVPHRPVAEYFVWF-K Mvan_3845|M.vanbaalenii_PYR-1 ADDPGDNDRRRPVGPYNTAYLIYTSGSTGLPKGVPVPHRPVAEYFVWF-K Mflv_2696|M.gilvum_PYR-GCK TDNPTDDVRVRPLRPENAAYLIYTSGSTGQPKGVPVPHRPVAEYFVWF-K MAV_3239|M.avium_104 IREQPVTAPPAPA-PDNIAYLIYTSGTTGVPKGVAVTHRNATQLFASLGA MSMEG_0402|M.smegmatis_MC2_155 VEIYPSTTLLTPS-PDDIAYMIYTSGTTGVPKGVAITHGNVTQVLDTL-P . . **:: ***:** ** * :.* : Mb0104|M.bovis_AF2122/97 RAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAAL Rv0101|M.tuberculosis_H37Rv RAYGWGAHDTVLQCAPLTSDISVEEIFGGAACGARLVRSAAMKTGDLAAL MMAR_0256|M.marinum_M PSYGWNSRDTILQCAPLTSDISVEEIFGAAVCGAELVRSAAMKTGDLGGL MUL_4858|M.ulcerans_Agy99 PSYGWNSQDTILQCAPLTSDISVEEIFGAAVCGAELVRSAAMKTGDLGGL MLBr_01996|M.leprae_Br4923 NAYGWGAHDTILQCAPLTSDISVEEIFGGAICGSKLVRSTAMKTGDLAEL MAB_0663|M.abscessus_ATCC_1997 DAYGWCAQDRILQCAPLTSDISVEEVFVAASRGVQVIRSAAMKSADLSAL TH_3141|M.thermoresistible__bu GDYQVDANDRLLQVASPSFDVSIAEIFGTLACGARLVIHRPGGLNDIGYL Mvan_3845|M.vanbaalenii_PYR-1 GDYRVDAGDRMLQVASPSFDISIAEVFGTLACGARLVIHRPGGLNDIGYL Mflv_2696|M.gilvum_PYR-GCK DEYEISESDRLLQVASPSFDVSIGEIFGTLACGGRLVIPKPDGLTDVAYL MAV_3239|M.avium_104 AGLPAAPGKVWGQCHSLAFDFSVWEIFGALLNGGRVLVVPDDVVRSPKDL MSMEG_0402|M.smegmatis_MC2_155 AELPAGPGAVWSQWHSLVFDVSVWEIWGALLHGGRLVIVPESIAGSPDDL * . *.*: *:: * .:: . * Mb0104|M.bovis_AF2122/97 VDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCS Rv0101|M.tuberculosis_H37Rv VDDLVARETTIVDLPTAVWQLLCADGDAIDAIGRSRLRQIVIGGEAIRCS MMAR_0256|M.marinum_M ARDIHALGPTVVDLPTAVWHLLCEDGDAVDVIGRSRLRQIVIGGESIRTS MUL_4858|M.ulcerans_Agy99 ARDIHALGPTVVDLPTAVWHLLCEDGDAVDVIGRSRLRQIVIGGESIRTS MLBr_01996|M.leprae_Br4923 ARDIFVQRATVIDLPTAVWHLLCDHSDAIDEINRSCLRQIVIGGEAVRPC MAB_0663|M.abscessus_ATCC_1997 VHDIREAGPTLLDLPTAVWHLLCEDAESLALIGACGVRQVVVGGEAIRPG TH_3141|M.thermoresistible__bu TALLQDEGITAMHFVPSLLGLFL---SLPGVNQWRTLQRVPIGGEPLPGE Mvan_3845|M.vanbaalenii_PYR-1 TALLRDEGITAMHFVPSLLGLFL---SLPGVNQWRTLQRVPIGGEALPGE Mflv_2696|M.gilvum_PYR-GCK TELLQREGITAMHFVPSLLGLFL---SLPGVNQWRTLERVPIGGEALPGE MAV_3239|M.avium_104 HALLVAERVDMLTQTPSEVGVLS---PDG-----LESTTLAVAGEACPVE MSMEG_0402|M.smegmatis_MC2_155 HALLVSEGVNVLYQTPSAVRMMS---PEG-----LEGTALVVAGEACPTE : : .: :: : :.**. Mb0104|M.bovis_AF2122/97 AVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGAL----- Rv0101|M.tuberculosis_H37Rv AVDKWLESAASQGISLLSSYGPTEATVVATFLPIVCDQTTMDGAL----- MMAR_0256|M.marinum_M TVDKWVNSPVLAPISLVSSYGPTEATVVATHLPIVYDGIAAAAHTR---- MUL_4858|M.ulcerans_Agy99 TVDKWVNSPALAPISLVSSYGPTEATVVATHLPIVYDGIAAAAHTR---- MLBr_01996|M.leprae_Br4923 AVDKWIDSGASQGISLMSTYGPTETTVVVTYLPIVCAPMTVESDAR---- MAB_0663|M.abscessus_ATCC_1997 AVDQWVKSTDKNGISLISTYGPTETTVVVTHLSIAAG----DGVDC---- TH_3141|M.thermoresistible__bu VADKFHATF---DALLHNFYGPTETVINASRYKVEGKQGTRIVPIGRPKI Mvan_3845|M.vanbaalenii_PYR-1 VADKFRATF---DALLHNFYGPTETVINATRFKVEGRQGTRIVPIGKPKI Mflv_2696|M.gilvum_PYR-GCK LADRFHATF---DALLHNFYGPTETIINTTRYKVEGTQGSRIVPIGTPKI MAV_3239|M.avium_104 VVDRWAP-----GRVMINVYGPTETTIVAAVSAPLT-PGPEAPPIGAPVP MSMEG_0402|M.smegmatis_MC2_155 VVDRWAV-----DRVMINAYGPTESTIYAAISAPLS-PGSDVVPIGSPVP .*:: : . *****: : .: Mb0104|M.bovis_AF2122/97 ---LRLGRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFG--TVTAAD Rv0101|M.tuberculosis_H37Rv ---LRLGRPILPNTVFLAFGEVVIVGDLVADGYLGIDGDGFG--TVTAAD MMAR_0256|M.marinum_M ---LRVGLPMAPNTVFIAFGEVVIAGPLVSDGYLGIDDSSFG--AVAPGD MUL_4858|M.ulcerans_Agy99 ---LRVGLPMVPNTVFIAFGEVVIAGPLVSDGYLGIDESSFG--AVAPGD MLBr_01996|M.leprae_Br4923 ---LRLGWPIVPNTVFIAFGELVIVGDLVSVGYLGIDSRNFG--TVTTTD MAB_0663|M.abscessus_ATCC_1997 ---RRMGVPVVPNTVFVAFGEVVIVGGTVSAGYLGTPSESFG--VVRTGE TH_3141|M.thermoresistible__bu NTQLHLLDNALQPVPVGVIGEIYIGGTHVAHGYHRRPGLTAERFVADPFN Mvan_3845|M.vanbaalenii_PYR-1 NTAIHILDDALQPVPVGSIGEIYIGGTHVARGYHHRPGLTAERFVADPFT Mflv_2696|M.gilvum_PYR-GCK NTTVHLLDDALRPVPVGAIGEIYIGGGHVARGYHRRPALTAERFVADPFT MAV_3239|M.avium_104 GTALRVLDAHLRPVPPGVVGELYVAGAGVSTGYLGRPGLTASRFVACPFG MSMEG_0402|M.smegmatis_MC2_155 KGATFVLDEWLRPVPPGVVGELYLAGRGVGVGYVGRSGLTGTRFVACPFG : . .**: : * *. ** .. . Mb0104|M.bovis_AF2122/97 GSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAED Rv0101|M.tuberculosis_H37Rv GSRRRAFATGDRVTVDAEGFPVFSGRKDAVVKISGKRVDIAEVTRRIAED MMAR_0256|M.marinum_M GSQLRAFATADRVTIDEEGFPVFAGRKDTIVKVAGKRVDTAAVARRISAD MUL_4858|M.ulcerans_Agy99 GSQLRAFATADRVTIDEEGFPVFAGRKDTVVKVAGKRVDTAAVARRISAD MLBr_01996|M.leprae_Br4923 GSCRRAFATADCVILDDEGFPVFSGRKDAVVKISGKRVDTAELIRRISTD MAB_0663|M.abscessus_ATCC_1997 GKSRPAFATADRVVFDEDGLPSFAGRRDAIVKISGKRIDTAAIIARVAED TH_3141|M.thermoresistible__bu -PGGRLYRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAAISVD Mvan_3845|M.vanbaalenii_PYR-1 -PGARMYRSGDLARRNADGDIEFVGRADEQVKIRGFRIELGDVAAAITVD Mflv_2696|M.gilvum_PYR-GCK -VGGRLYRSGDLARRNADGDLEFVGRADDQVKIRGFRIELGEVAAAISVD MAV_3239|M.avium_104 GAGERMYRTGDLVRWGADGQLQYLGRADEQVKIRGYRIELGEIQSALAAL MSMEG_0402|M.smegmatis_MC2_155 EPGARMYRTGDLVRWGDDGQLQYLGRADEQVKIRGYRIELGEIQAALSDV : :.* . . :* : ** * **: * *:: . : :: Mb0104|M.bovis_AF2122/97 PAVSDVAVELHSGSLGVWFKSQRTREGEQ------DAAAATRIRLVLVSL Rv0101|M.tuberculosis_H37Rv PAVSDVAVELHSGSLGVWFKSQRTREGEQ------DAAAATRIRLVLVSL MMAR_0256|M.marinum_M PTVCDVAVEPHDGRLGVWFETERTREAAE------DGATAGRIGLTLASL MUL_4858|M.ulcerans_Agy99 PTVCDVAVEPHDGRLGVWFETERTREAAE------DGATAGRIGLALASL MLBr_01996|M.leprae_Br4923 PNVSDVAVEVYNGRLGVWFETKLTREGVD------DAAAATRSRLILASL MAB_0663|M.abscessus_ATCC_1997 RAVADVDVAVHNGALVVWFQ---TRHGVD------DNESAVSIRRLLVEL TH_3141|M.thermoresistible__bu PSVGQAVVVATDLPNVGRSLVGYLTPVSGESTDSVAVERIRARVAAALPE Mvan_3845|M.vanbaalenii_PYR-1 PSVGQAVVVVSDLPNLGKSLVAYLTPADG---AGVDVDRIRTRVAAALPE Mflv_2696|M.gilvum_PYR-GCK PSVGQAVVLGQDLPGLGMSLVGYVTPAAG---EDVDLARVRERVAAALPD MAV_3239|M.avium_104 DGVDQAAVIAREDRPGDKRLVGYVT-------GTADLAQLRTALAERLPG MSMEG_0402|M.smegmatis_MC2_155 DGVDQAVVIAREDRPGDKRLVGYIT-------GTADPAAARSELTNRLPA * :. * . Mb0104|M.bovis_AF2122/97 GVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLS Rv0101|M.tuberculosis_H37Rv GVSSFFVVGVPNIPRKPNGKIDSDNLPRLPQWSAAGLNTAETGQRAAGLS MMAR_0256|M.marinum_M GVPAFFVVAVPSIPRKPNGKVDGARLHTLPQLADAVPSDAEAGESAAGLA MUL_4858|M.ulcerans_Agy99 GVPAFFVVAVPSIPRKPNGKVDGARLHTLPQLADAVPRDAEAGESAAGLA MLBr_01996|M.leprae_Br4923 GVSSFFVVGVPCIPRKPNGKIDRDNLLVMPQLVDSVQNYAGSGEGAAGLA MAB_0663|M.abscessus_ATCC_1997 GVSSFVVVAVPSIPRKPNGKVDKDGLRALPQFVEAVPDEAKAGELAAGLA TH_3141|M.thermoresistible__bu YMVPAAYVVLDEIPITTHGKIDRAALP-EPQIASMIEYREPATDTEREVA Mvan_3845|M.vanbaalenii_PYR-1 YMTPAAYVVVDEIPITAHGKIDRAALP-EPEIAPTTEFREPAAGTEAHLA Mflv_2696|M.gilvum_PYR-GCK YMTPAGYVVLDEIPITAHGKIDRAALP-LPEITTATDYREPQTETEQHLA MAV_3239|M.avium_104 YMVPAAVLMLDALPLTPSGKLDTGALP-APDYQGPEGYLAPAGAVEEILA MSMEG_0402|M.smegmatis_MC2_155 YMVPAAVVTLETLPLTVNGKLDRRALP-APEYQSAQRYRAPETETEKTLA : . : : :* . **:* * *: :: Mb0104|M.bovis_AF2122/97 QIWSRQLG--RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLI Rv0101|M.tuberculosis_H37Rv QIWSRQLG--RAIGPDSSLLGEGIGSLDLIRILPETRRYLGWRLSLLDLI MMAR_0256|M.marinum_M RVWSRHLG--RPLAADSSLLGAGIGSLDLIRILPDTRRYLGRHLSVLELI MUL_4858|M.ulcerans_Agy99 RVWSCHLG--RPLAADSSLLGAGIGSLDLIRILPDTRRYLGRHLSVLELI MLBr_01996|M.leprae_Br4923 EIWSRHLG--RAILPDSSLLDEGIGSVDLIRILPDTRRHLGRHLSLLDLI MAB_0663|M.abscessus_ATCC_1997 RIWSELLG--RRIGAESSLLAEGIGSLDLIRILPASRRHLGRELSVLDLI TH_3141|M.thermoresistible__bu RLFGDLLGRSERIGADDSFFDLGGHSLLATKLVAAVRSAFGVDIGVQDVF Mvan_3845|M.vanbaalenii_PYR-1 QLFAELLG-HEKVGADDSFFDLGGHSLLATKLVAELRAGFGVDVEVRDIF Mflv_2696|M.gilvum_PYR-GCK QLFSELLG-VARVGVDDSFFELGGHSLLATKLVSAVRSRCGVDMEIREIF MAV_3239|M.avium_104 WLYAQVLGLPRRVGVQESFFDLGGDSLSAMRLVAAIYNALDIHLPVRAVF MSMEG_0402|M.smegmatis_MC2_155 GIFAHVLGVER-IGLDDSFFDLGGDSISAMRVTAAVNTALDADLSVRTLF ::. ** : :.*:: * *: :: . . : : :: Mb0104|M.bovis_AF2122/97 GADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQ Rv0101|M.tuberculosis_H37Rv GADTAANLADYAPTPDAPTGEDRFRPLVAAQRPAAIPLSFAQRRLWFLDQ MMAR_0256|M.marinum_M SADTAANLVCDLGSNPAAPATD---------------------------- MUL_4858|M.ulcerans_Agy99 SADTAANLVCDLGSNPAAPATD---------------------------- MLBr_01996|M.leprae_Br4923 SADNAANLT-------AAQTAN---------------------------- MAB_0663|M.abscessus_ATCC_1997 SADSAAYLA-------AAGAAV---------------------------- TH_3141|M.thermoresistible__bu ELGTVARLAGRIDELRSGSGGP---------------------------- Mvan_3845|M.vanbaalenii_PYR-1 ENATIARLAAHLDTMGRATIGT---------------------------- Mflv_2696|M.gilvum_PYR-GCK ELGTVARLAERVDELAAGGSAP---------------------------- MAV_3239|M.avium_104 EAPSVRSLSQRLNADPAVAQGL---------------------------- MSMEG_0402|M.smegmatis_MC2_155 EAPTVAKLSLHVEHD-AGERTD---------------------------- . * Mb0104|M.bovis_AF2122/97 LQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVP Rv0101|M.tuberculosis_H37Rv LQRPAPVYNMAVALRLRGYLDTEALGAAVADVVGRHESLRTVFPAVDGVP MMAR_0256|M.marinum_M -----------------GWLDAETAAAIERDLVSLGSQC----------- MUL_4858|M.ulcerans_Agy99 -----------------GWLDAETAAAIERDLVSLGSQC----------- MLBr_01996|M.leprae_Br4923 -----------------VWMDVGTAAEIERDLASLCRQR----------- MAB_0663|M.abscessus_ATCC_1997 -----------------DELARRDIADIATDLERMTHSR----------- TH_3141|M.thermoresistible__bu --------------------LRPRLTPQHFDGPAPLSSSQL--------- Mvan_3845|M.vanbaalenii_PYR-1 --------------------RRPRLVAAPLDGPAPLSSSQL--------- Mflv_2696|M.gilvum_PYR-GCK --------------------LRPRLLAVPHDGPAPMSAAQL--------- MAV_3239|M.avium_104 --------------------RADFASVHGRDATEVYAS------------ MSMEG_0402|M.smegmatis_MC2_155 --------------------RVSFAAVHGSDVTEVHAR------------ * Mb0104|M.bovis_AF2122/97 RQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTW Rv0101|M.tuberculosis_H37Rv RQLVIEARRADLGCDIVDATAWPADRLQRAIEEAARHSFDLATEIPLRTW MMAR_0256|M.marinum_M -----------------TPQPLGAKPPPHDRAAAP--------------- MUL_4858|M.ulcerans_Agy99 -----------------TPQPLGADPPPHDRAAAP--------------- MLBr_01996|M.leprae_Br4923 -----------------NATEFSVKQTRNSHQKQA--------------- MAB_0663|M.abscessus_ATCC_1997 -----------------AFAALCGN-ASGAVDDGP--------------- TH_3141|M.thermoresistible__bu --------------RSWFAYRVDGPSVVNNIPFAAR-------------- Mvan_3845|M.vanbaalenii_PYR-1 --------------RSWFGYRIEGRSPVNNIPFAAR-------------- Mflv_2696|M.gilvum_PYR-GCK --------------RQWFQYRIEGPGPVNNVPFAAR-------------- MAV_3239|M.avium_104 ------------------------DLTLDKFIDAAT-------------- MSMEG_0402|M.smegmatis_MC2_155 ------------------------DLTLDKFIDAPT-------------- . Mb0104|M.bovis_AF2122/97 LFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYA-------SRCAGR Rv0101|M.tuberculosis_H37Rv LFRIADDEHVLVAVAHHIAADGWSVAPLTADLSAAYA-------SRCAGR MMAR_0256|M.marinum_M ---------IVVLGASGIVGTGFARAVLERKQAGLAC-------PEIV-- MUL_4858|M.ulcerans_Agy99 ---------IVVLGASGIVGTGFARAVLQRKQAGLAC-------PEIV-- MLBr_01996|M.leprae_Br4923 ---------IVVLGASGILGTGFAQAVLDLRQSGVLC-------PEVV-- MAB_0663|M.abscessus_ATCC_1997 ---------IVVLGASGIVGTGFARATLELKREGRLR-------PDVV-- TH_3141|M.thermoresistible__bu -----------LHGPVDVDALEAAIGDVIARHEILRTVYREIDG------ Mvan_3845|M.vanbaalenii_PYR-1 -----------LTGPCDVDAFVAAIRDVVERHAILRTTYREIDG------ Mflv_2696|M.gilvum_PYR-GCK -----------FAGPCDVDALIEAVRDVVNRHESLRTTFCEIDG------ MAV_3239|M.avium_104 -----------LSAAPALPGPGAEVRTVLLTGATGFLGRYLVLQ------ MSMEG_0402|M.smegmatis_MC2_155 -----------LRTATTLPRPDGAVQTVLLTGATGFLGRYLLLE------ . . : : Mb0104|M.bovis_AF2122/97 APDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERL Rv0101|M.tuberculosis_H37Rv APDWAPLPVQYVDYTLWQREILGDLDDSDSPIAAQLAYWENALAGMPERL MMAR_0256|M.marinum_M ---------------------------------------------LASRS MUL_4858|M.ulcerans_Agy99 ---------------------------------------------LASRS MLBr_01996|M.leprae_Br4923 ---------------------------------------------LATRA MAB_0663|M.abscessus_ATCC_1997 ---------------------------------------------LVTRS TH_3141|M.thermoresistible__bu ---------------------------------------------VPYQI Mvan_3845|M.vanbaalenii_PYR-1 ---------------------------------------------VPYQI Mflv_2696|M.gilvum_PYR-GCK ---------------------------------------------VPYQL MAV_3239|M.avium_104 ---------------------------------------------WLERL MSMEG_0402|M.smegmatis_MC2_155 ---------------------------------------------WLRQL : Mb0104|M.bovis_AF2122/97 RLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGL Rv0101|M.tuberculosis_H37Rv RLPTARPYPPVADQRGASLVVDWPASVQQQVRRIARQHNATSFMVVAAGL MMAR_0256|M.marinum_M KPPEHGPWSALRG------------------------------------- MUL_4858|M.ulcerans_Agy99 KPPEHGPWSALRD------------------------------------- MLBr_01996|M.leprae_Br4923 RLPEGDPWTALQG------------------------------------- MAB_0663|M.abscessus_ATCC_1997 PLPDDGPWPGLTG------------------------------------- TH_3141|M.thermoresistible__bu VLPTEP-VPVRRAD------------------------------------ Mvan_3845|M.vanbaalenii_PYR-1 VNPISD-VPVRRAR------------------------------------ Mflv_2696|M.gilvum_PYR-GCK VNAPDPGFPVRRDS------------------------------------ MAV_3239|M.avium_104 ELADGKLICLVRAA------------------------------------ MSMEG_0402|M.smegmatis_MC2_155 RRVDDKVICLVRGK------------------------------------ Mb0104|M.bovis_AF2122/97 AVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSF Rv0101|M.tuberculosis_H37Rv AVLLSKLSGSPDVAVGFPIAGRSDPALDNLVGFFVNTLVLRVNLAGDPSF MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------GQGEQWL Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------GEGEQWL Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------GPDDAWL MAV_3239|M.avium_104 -------------------------------------------SDD---- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------SDE---- Mb0104|M.bovis_AF2122/97 AELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN Rv0101|M.tuberculosis_H37Rv AELLGQVRARSLAAYENQDVPFEVLVDRLKPTRALTHHPLIQVMLAWQDN MMAR_0256|M.marinum_M ---LEGIRIEQLGAT----------------------------------- MUL_4858|M.ulcerans_Agy99 ---LEGIRIEQLGAA----------------------------------- MLBr_01996|M.leprae_Br4923 ---VDGVRIERISFE----------------------------------- MAB_0663|M.abscessus_ATCC_1997 ---VGGVRVLHAGPE----------------------------------- TH_3141|M.thermoresistible__bu RAELDAERRHVFDLENE--------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 QAELDRERKHTFDLEED--------------------------------- Mflv_2696|M.gilvum_PYR-GCK VGALDDERRRVFDLENQ--------------------------------- MAV_3239|M.avium_104 ----DARRRLERTFDSG--------------------------------- MSMEG_0402|M.smegmatis_MC2_155 ----DARRRLEATFDT---------------------------------- * Mb0104|M.bovis_AF2122/97 PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYR Rv0101|M.tuberculosis_H37Rv PVGQLNLGDLQATPMPIDTRTARMDLVFSLAERFSEGSEPAGIGGAVEYR MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 TDVFEAQAIDVLIERLRKVLVAVAAAPERTV------SSIDALDGTERAR Rv0101|M.tuberculosis_H37Rv TDVFEAQAIDVLIERLRKVLVAVAAAPERTV------SSIDALDGTERAR MMAR_0256|M.marinum_M ---LGAADLDALIC-----------------------------DTGARSL MUL_4858|M.ulcerans_Agy99 ---LDAADLDALIR-----------------------------DTGARSL MLBr_01996|M.leprae_Br4923 ---NGPGELEALIR-----------------------------DTDAGTL MAB_0663|M.abscessus_ATCC_1997 ---FNPGAVDELIR-----------------------------VTGARTL TH_3141|M.thermoresistible__bu ----RPIRPAILSLRPDAGSPD----SPAGD--------VHVLSLVMHHI Mvan_3845|M.vanbaalenii_PYR-1 ----WPIRAAVFTVGAVSPASDGGAVSPASDGGAVDPASDHVLSVVIHHI Mflv_2696|M.gilvum_PYR-GCK ----WPIRVAVLSIPG-----------------------EHALSVVVHHI MAV_3239|M.avium_104 ----DPALLR------------------------------YFHELAADHL MSMEG_0402|M.smegmatis_MC2_155 ----DPLLRK------------------------------HFNELATERL . Mb0104|M.bovis_AF2122/97 LDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELD Rv0101|M.tuberculosis_H37Rv LDEWGNRAVLTAPAPTPVSIPQMLAAQVARIPEAEAVCCGDASMTYRELD MMAR_0256|M.marinum_M INCIGNTNVLVP---------------------------------YRGLR MUL_4858|M.ulcerans_Agy99 INCIGNTNVLVP---------------------------------YRGLR MLBr_01996|M.leprae_Br4923 VNGVGNTNMLVP---------------------------------YRELR MAB_0663|M.abscessus_ATCC_1997 VNCIGNTNVLAP---------------------------------YRDIR TH_3141|M.thermoresistible__bu AGDHWSATVLFTD----------------------------LLTAYRART Mvan_3845|M.vanbaalenii_PYR-1 AGDHWSGGVLFTD----------------------------LVAAYRARK Mflv_2696|M.gilvum_PYR-GCK AADHWSGGVLFTE----------------------------LLTAYRARR MAV_3239|M.avium_104 EVIAGDKGRANLG----------------------------LDDRTWQRL MSMEG_0402|M.smegmatis_MC2_155 QVVAGDKGQPNLG----------------------------LDEQTWQRL . Mb0104|M.bovis_AF2122/97 EASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDP Rv0101|M.tuberculosis_H37Rv EASNRLAHRLAGCGAGPGECVALLFERCAPAVVAMVAVLKTGAAYLPIDP MMAR_0256|M.marinum_M AAN--------------VELVSTVAQVCAQRDVRLVHLS----------- MUL_4858|M.ulcerans_Agy99 AAN--------------VELVSTVAQVCAQRDVRLVHLS----------- MLBr_01996|M.leprae_Br4923 LAN--------------VELVSAIVDICASYSTRLVHLS----------- MAB_0663|M.abscessus_ATCC_1997 DAN--------------VEWVSAVTRACTSGGVRLIHMS----------- TH_3141|M.thermoresistible__bu AGQ--------------EPAWAPLPVQYADFGAWESELL----------- Mvan_3845|M.vanbaalenii_PYR-1 AGE--------------RPTWAPLPVQYTDYGAWQAELL----------- Mflv_2696|M.gilvum_PYR-GCK AGE--------------APTWAPLPVQYADYAAWQSALL----------- MAV_3239|M.avium_104 ADT--------------VDLIVDAAAVVNGVLPYQELFG----------- MSMEG_0402|M.smegmatis_MC2_155 AES--------------VDLIVDSAAFVNSVLPYSELFG----------- . Mb0104|M.bovis_AF2122/97 ANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTP Rv0101|M.tuberculosis_H37Rv ANPPPRVAFMLGDAVPVAAVTTAGLRSRLAGHDLPIIDVVDALAAYPGTP MMAR_0256|M.marinum_M -------TFVISADVTAPRVTDPRM-----------------------SP MUL_4858|M.ulcerans_Agy99 -------TFVISADVTAPRVTDPRM-----------------------SP MLBr_01996|M.leprae_Br4923 -------SFVVNADVTVPQVTDPRE-----------------------TP MAB_0663|M.abscessus_ATCC_1997 -------TFVVNADAVAAQVTDPRE-----------------------AV TH_3141|M.thermoresistible__bu -------AEETGIAGPQREYWTRQLAG----------------LPEETGL Mvan_3845|M.vanbaalenii_PYR-1 -------SDDTGIAGPQREYWIRQLAD----------------APVESGL Mflv_2696|M.gilvum_PYR-GCK -------ADDSGIVAAQRRYWTQQLEG----------------LSAETGL MAV_3239|M.avium_104 -------PNVAGTAELIRLALSTRLKP----------------YSYVS-- MSMEG_0402|M.smegmatis_MC2_155 -------PNVVGTAELIRFALTSKLKP----------------FNFVS-- . . Mb0104|M.bovis_AF2122/97 PPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWS Rv0101|M.tuberculosis_H37Rv PPMPAAVNLAYILYTSGTTGEPKGVGITHRNVTRLFASLPARLSAAQVWS MMAR_0256|M.marinum_M YPYAASKSLAELIVAA----SSPALDFTIVRLPRVLG------EDYQLRE MUL_4858|M.ulcerans_Agy99 YPYAASKSLAELIVAA----SSPVLDFTIVRLPRVLG------EDYQLRE MLBr_01996|M.leprae_Br4923 YPYAASKSLAELVVAG----SPSALDFTIVRLPRVLG------EDYQLRN MAB_0663|M.abscessus_ATCC_1997 YPYAASKALAELIVAA----APGELDFTLVRLPRVLG------EAGQLGR TH_3141|M.thermoresistible__bu RPDFPRPPVPSGLAEAVEFTIDAAVREKLAGLCRDLG----ITEFMALQA Mvan_3845|M.vanbaalenii_PYR-1 PLEFSRPRLPSGKGDAVEFTIDGQVRRQITELCRELG----ITEFMLLQA Mflv_2696|M.gilvum_PYR-GCK QPDLVRPSVPSGAADAVEFTLDAAIREKLVTLSREVG----ATEFMLLQA MAV_3239|M.avium_104 TANVGDQIEPSAFTEDADIRVAGPIRTIDGGYGNGYGNSKWAGEVLLREA MSMEG_0402|M.smegmatis_MC2_155 TSDVGRQIEPSRFTEQADIRLVSATRKIEVGYANGYGNSKWAGEVLLREA . . . . Mb0104|M.bovis_AF2122/97 QCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVL Rv0101|M.tuberculosis_H37Rv QCHSYGFDASAWEIWGALLGGGRLVIVPESVAASPNDFHGLLVAEHVSVL MMAR_0256|M.marinum_M SAD--------------------------------------------ILV MUL_4858|M.ulcerans_Agy99 SAD--------------------------------------------ILV MLBr_01996|M.leprae_Br4923 SSD--------------------------------------------ILL MAB_0663|M.abscessus_ATCC_1997 SAD--------------------------------------------ILV TH_3141|M.thermoresistible__bu AVAVV------------------------------------------LHK Mvan_3845|M.vanbaalenii_PYR-1 AVAVT------------------------------------------LAK Mflv_2696|M.gilvum_PYR-GCK AVAVT------------------------------------------LYK MAV_3239|M.avium_104 HDLCG------------------------------------------LPV MSMEG_0402|M.smegmatis_MC2_155 HDHCG------------------------------------------LPV Mb0104|M.bovis_AF2122/97 TQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTET Rv0101|M.tuberculosis_H37Rv TQTPAAVAMLPTQGLESVALVVAGEACPAALVDRWAPGRVMLNAYGPTET MMAR_0256|M.marinum_M SVVDACMALRAFPTLTLTEEVTTGRAAAQAILG----------------- MUL_4858|M.ulcerans_Agy99 SVVDACMALRSFPTLTLTEEVTTGRAAAQAILG----------------- MLBr_01996|M.leprae_Br4923 SIVDACIALRAYPSATVTEEVTTGRAAAKAILG----------------- MAB_0663|M.abscessus_ATCC_1997 SIVDACMALHAFPSVRLIEEVTTGASAARAILG----------------- TH_3141|M.thermoresistible__bu AGSGSDIPLGTPVAGRSEPELDQLVGFFINILVLR--------------- Mvan_3845|M.vanbaalenii_PYR-1 VGGGLDIPLGTPVAGRSEAELEQLVGFFVNFVVLR--------------- Mflv_2696|M.gilvum_PYR-GCK AGEGPDIPLGTPVAGRTESELDQLIGFFINILVLR--------------- MAV_3239|M.avium_104 SVFRCDMILADTSYAGQLNLPDMFTRLLFSVVASG--------------- MSMEG_0402|M.smegmatis_MC2_155 AVFRSGMIMVDPTYAGQLNVTDTVSRMVLSIVATG--------------- : : .: Mb0104|M.bovis_AF2122/97 TICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAG Rv0101|M.tuberculosis_H37Rv TICAAISAPLRPGSGMPPIGVPVSGAALFVLDSWLRPVPAGVAGELYIAG MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 AGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGR Rv0101|M.tuberculosis_H37Rv AGVGVGYWRRAGLTASRFVACPFGGSGARMYRTGDLVCWRADGQLEFLGR MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 TDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATE Rv0101|M.tuberculosis_H37Rv TDDQVKIRGYRIELGEVATALAELAGVGQAVVIAREDRPGDKRLVGYATE MMAR_0256|M.marinum_M ----------------LLPQFSGAAGLGHGITVVRG---AAVQYRELLSG MUL_4858|M.ulcerans_Agy99 ----------------LLPQFSGAAGLGHGITVVRG---AAVQYRELLSG MLBr_01996|M.leprae_Br4923 ----------------VVSALARSGQLGSGISVVRG---EAVAYADFLSE MAB_0663|M.abscessus_ATCC_1997 ----------------VAAAPS---PLGRGVNVVRG---MPVSYTDFLGG TH_3141|M.thermoresistible__bu ------------------NDLSGNPSLREVCRRAREMALAAYAHQDLPFD Mvan_3845|M.vanbaalenii_PYR-1 ------------------NDLRGNPTLREVLIRAREMALSAYSNQDVPFE Mflv_2696|M.gilvum_PYR-GCK ------------------NDLRDNPSLRDVGFRSREMALAAYAHQDLPFD MAV_3239|M.avium_104 ------------------VAPRSFYRLDAHGNRQR------AHFDALPVE MSMEG_0402|M.smegmatis_MC2_155 ------------------VAPGSFYQRGDNGERQR------AHFDGLPVD * Mb0104|M.bovis_AF2122/97 IAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAP Rv0101|M.tuberculosis_H37Rv IAPGAVDPAGLRAQLAQRLPGYLVPAAVVVIDALPLTVNGKLDHRALPAP MMAR_0256|M.marinum_M YALDEIDAAEWKHRLDQ--------------------------------S MUL_4858|M.ulcerans_Agy99 YALDEIDAAEWKHRLDQ--------------------------------S MLBr_01996|M.leprae_Br4923 FASDELNMAEWKYRLDQ--------------------------------S MAB_0663|M.abscessus_ATCC_1997 FGIEGLELREWKRLLDR--------------------------------S TH_3141|M.thermoresistible__bu QVVDAVSPVRTLARNPLFSVVVHVREQLPENRVIDHGPDG--------DT Mvan_3845|M.vanbaalenii_PYR-1 QVVEAVNPPRTLARNPLFQVVVHVREQLPQRQMIDT------------DT Mflv_2696|M.gilvum_PYR-GCK QVVDAVSPVRSLSRNPLFGVVVHVREELPQDRVIATGSDG--------ET MAV_3239|M.avium_104 FVAEAIATLGAQVGR----DAGTG------------------------FA MSMEG_0402|M.smegmatis_MC2_155 FVAQAITKLGWQVARSVTDSTASG------------------------FE : Mb0104|M.bovis_AF2122/97 EYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGD------ Rv0101|M.tuberculosis_H37Rv EYGDTNGYRAPAGPVEKTVAGIFARVLGLERVGVDDSFFELGGD------ MMAR_0256|M.marinum_M DWARRN----------------------PQRWSVVDAWVSLG-------- MUL_4858|M.ulcerans_Agy99 DWARRN----------------------PQRWSVVDAWVSLG-------- MLBr_01996|M.leprae_Br4923 DWAKRN----------------------PRRWSVIDAWFTLG-------- MAB_0663|M.abscessus_ATCC_1997 AWAKRN----------------------PRRWSVIDAWAGLG-------- TH_3141|M.thermoresistible__bu TVTVLEP---------------------PFDAAHADLSLNFFAAEDGGGY Mvan_3845|M.vanbaalenii_PYR-1 EFTALEP---------------------TFDIAQADLSLNFLA--DGTGY Mflv_2696|M.gilvum_PYR-GCK TFTALEP---------------------TFDMAHADLSVNFFAG--GNGY MAV_3239|M.avium_104 TYHVMNP---------------------HDDGIGLDEYVDWLID------ MSMEG_0402|M.smegmatis_MC2_155 TYHVMNP---------------------HDDGIGIDTYIDWLIE------ : * Mb0104|M.bovis_AF2122/97 ----SLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSD Rv0101|M.tuberculosis_H37Rv ----SLAAMRVIAAINTTLNADLPVRALLHASSTRGLSQLLGRDARPTSD MMAR_0256|M.marinum_M --------MRLGARSYSQYLAGYPSIPLQVGT------------------ MUL_4858|M.ulcerans_Agy99 --------MRLGARSYSQYLAGYPSIPLQVGT------------------ MLBr_01996|M.leprae_Br4923 --------MMFEMRSY----AEYPTMALGVES------------------ MAB_0663|M.abscessus_ATCC_1997 --------MRLGSRTYGDYLAGHRTIPLETAH------------------ TH_3141|M.thermoresistible__bu RGHVIYRPELYSRDTAQRFADWLGRVVTAFAE------------------ Mvan_3845|M.vanbaalenii_PYR-1 RGYLIYRPELYARRTIERLGRWLPRVVAAFVD------------------ Mflv_2696|M.gilvum_PYR-GCK RGHVIYRTELYTRATAERFAGWLSAVITAFAD------------------ MAV_3239|M.avium_104 --------AGYPIERVDDFDQWLHRMETALHA------------------ MSMEG_0402|M.smegmatis_MC2_155 --------AGYPIERIEDFGEWLQRFEAALQG------------------ Mb0104|M.bovis_AF2122/97 PRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPGPSPELRTVLLTG Rv0101|M.tuberculosis_H37Rv PRLVSVHGDNPTEVHASDLTLDRFIDADTLATAVNLPGPSPELRTVLLTG MMAR_0256|M.marinum_M --------------------------------VAEIAAPPTALRALLEQG MUL_4858|M.ulcerans_Agy99 --------------------------------VAEIAAPPTALRALLEQG MLBr_01996|M.leprae_Br4923 --------------------------------VAELAAPPESIRALLAHG MAB_0663|M.abscessus_ATCC_1997 --------------------------------IAELFAVPESIRDLLTQG TH_3141|M.thermoresistible__bu --------------------------------RPDITLRELEIGAPGERR Mvan_3845|M.vanbaalenii_PYR-1 --------------------------------TPDRALGDVDIVSAEERQ Mflv_2696|M.gilvum_PYR-GCK --------------------------------DPERHVDDVVIAEPVRP- MAV_3239|M.avium_104 --------------------------------LSERQRHQSVLQLLALR- MSMEG_0402|M.smegmatis_MC2_155 --------------------------------LSDQQRQNSVLQMLTLLK : : Mb0104|M.bovis_AF2122/97 ATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSGDPEL Rv0101|M.tuberculosis_H37Rv ATGFLGRYLVLELLRRLDVDGRLICLVRAESDEDARRRLEKTFDSGDPEL MMAR_0256|M.marinum_M CAQPPRPALA---------------------------------------- MUL_4858|M.ulcerans_Agy99 CAQPPRPALA---------------------------------------- MLBr_01996|M.leprae_Br4923 CSQPLKYTGR---------------------------------------- MAB_0663|M.abscessus_ATCC_1997 CSR----------------------------------------------- TH_3141|M.thermoresistible__bu RILEEWG-GGTVYVLDETLQPVPVGVVGDVYTAGPALAAAHWTRAGVTA- Mvan_3845|M.vanbaalenii_PYR-1 RVSQEWSTGARVQVLDADLAPAPVGVFGDLYLSG---------------- Mflv_2696|M.gilvum_PYR-GCK ------GDGAEAVLLDGAGHPVPVGVVADVHYAGAPDRRGDRARWTEDGR MAV_3239|M.avium_104 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 LRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNA Rv0101|M.tuberculosis_H37Rv LRHFKELAADRLEVVAGDKSEPDLGLDQPMWRRLAETVDLIVDSAAMVNA MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu ------------TRLVADPVGNRPGARLYRTGDRARWI--------ADGV Mvan_3845|M.vanbaalenii_PYR-1 ----------------------GPFAQRHRTGDRARWD--------DDGR Mflv_2696|M.gilvum_PYR-GCK LQYVERVDHDLEAALAAVPGVAAAAVRTWEIGHRTAVVGYVVPAEPVDDP MAV_3239|M.avium_104 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 FPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDA Rv0101|M.tuberculosis_H37Rv FPYHELFGPNVAGTAELIRIALTTKLKPFTYVSTADVGAAIEPSAFTEDA MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu LEFVDAQP-PTIPAVRP------------------DSGQRPGGPPATDTE Mvan_3845|M.vanbaalenii_PYR-1 LEIAARAPGATVVEVAP------------------PAVEFE--EPRTDSE Mflv_2696|M.gilvum_PYR-GCK ASFAETVRAAVAPESAPTSITVLDALPATRRALPAPRVGGPSEPARTDTE MAV_3239|M.avium_104 ------------------------------------NARHVPPADPARGC MSMEG_0402|M.smegmatis_MC2_155 -----------------------------------QQAGELQPPVPTRGS Mb0104|M.bovis_AF2122/97 DIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMIL Rv0101|M.tuberculosis_H37Rv DIRVISPTRTVDGGWAGGYGTSKWAGEVLLREANDLCALPVAVFRCGMIL MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu RALATLLAEVLDTEVTG----RDDDFFSLGGDSILAVQLAARARDTGLKL Mvan_3845|M.vanbaalenii_PYR-1 RALAALLSELLATEEVG----RHDDFFGLGGDSVLAVQLAARARDTGLDL Mflv_2696|M.gilvum_PYR-GCK KALVGMLADVLVEVHDGTGIGRFDDFFELGGDSILAVQLAARAKQAGLRL MAV_3239|M.avium_104 LGPTERFRAAVQEAKIG-------------------------ADNDIPHI MSMEG_0402|M.smegmatis_MC2_155 FAPADRFQAAVRDANIG-------------------------VEGEIPHV Mb0104|M.bovis_AF2122/97 ADTSYAGQLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLP Rv0101|M.tuberculosis_H37Rv ADTSYAGQLNMSDWVTRMVLSLMATGIAPRSFYEPDSEGNRQRAHFDGLP MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu TARMVFEHPTLHELAAAVEAREAVEARETAEAGGAEAGGAESGGGADGAE Mvan_3845|M.vanbaalenii_PYR-1 TARMVFEHPRLAELAAALDS----------------------GAGAAAEQ Mflv_2696|M.gilvum_PYR-GCK SARMVFEHPVVHDLAVALDT-------------------------AKTPE MAV_3239|M.avium_104 TAPVIVKYVTDLQLLGLL-------------------------------- MSMEG_0402|M.smegmatis_MC2_155 TREVIVKYVTDLQLLGLL-------------------------------- Mb0104|M.bovis_AF2122/97 VTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGY Rv0101|M.tuberculosis_H37Rv VTFVAEAIAVLGARVAGSSLAGFATYHVMNPHDDGIGLDEYVDWLIEAGY MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu RGAAAGDSGNGAASHAPMSTSGLSAEQLSALTASWNPAGEDAP------- Mvan_3845|M.vanbaalenii_PYR-1 P----------DTHHAPMSVSGLSEDELAALTASWG-TGE---------- Mflv_2696|M.gilvum_PYR-GCK VA---------DVRHDPMSASGLTPEELAMVATSWAAEQDGSP------- MAV_3239|M.avium_104 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 PIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTR Rv0101|M.tuberculosis_H37Rv PIRRIDDFAEWLQRFEASLGALPDRQRRHSVLPMLLASNSQRLQPLKPTR MMAR_0256|M.marinum_M -------------------------------------------------- MUL_4858|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01996|M.leprae_Br4923 -------------------------------------------------- MAB_0663|M.abscessus_ATCC_1997 -------------------------------------------------- TH_3141|M.thermoresistible__bu -------------------------------------------------- Mvan_3845|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_2696|M.gilvum_PYR-GCK -------------------------------------------------- MAV_3239|M.avium_104 -------------------------------------------------- MSMEG_0402|M.smegmatis_MC2_155 -------------------------------------------------- Mb0104|M.bovis_AF2122/97 GCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL Rv0101|M.tuberculosis_H37Rv GCSAPTDRFRAAVRAAKVGSDKDNPDIPHVSAPTIINYVTNLQLLGLL MMAR_0256|M.marinum_M ------------------------------------------------ MUL_4858|M.ulcerans_Agy99 ------------------------------------------------ MLBr_01996|M.leprae_Br4923 ------------------------------------------------ MAB_0663|M.abscessus_ATCC_1997 ------------------------------------------------ TH_3141|M.thermoresistible__bu ------------------------------------------------ Mvan_3845|M.vanbaalenii_PYR-1 ------------------------------------------------ Mflv_2696|M.gilvum_PYR-GCK ------------------------------------------------ MAV_3239|M.avium_104 ------------------------------------------------ MSMEG_0402|M.smegmatis_MC2_155 ------------------------------------------------