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MPDVIAHHGLLKDTRLHVDDTGGPGRPVLLMHPWPLSGQSWSAQVPVLHAAGYRVVTYDRRGFGRSDKPL TGYSYSQLTQDLHTLVESLDLRDLTLVGSSMGGGEVARYLSTYGPERVRSVVFASSVTPYLLQTTDNPDG PLTMKDAARATASFVKDQDAFYDHQMTEFFSANGQLRVSPATRAEALRLCKQAGKEASLACMAAWANTDF RPDLTRVSVPALIIHGEGDESVPLAGSARRTHRAIPGSRLCVIADGPHGCHISHAQEFNAALLDFLAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5175 | - | - | 100% (278) | non-haem bromoperoxidase BPO-A2 |
| M. avium 104 | MAV_0592 | - | 1e-14 | 28.32% (279) | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase |
| M. avium 104 | MAV_4061 | - | 2e-14 | 27.90% (276) | hydrolase, alpha/beta fold family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0569 | bpoC | 1e-13 | 26.45% (276) | peroxidase BpoC |
| M. gilvum PYR-GCK | Mflv_2561 | - | 2e-92 | 58.70% (276) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv0554 | bpoC | 1e-13 | 26.45% (276) | peroxidase BpoC |
| M. leprae Br4923 | MLBr_02269 | - | 2e-12 | 26.57% (271) | putative hydrolase |
| M. abscessus ATCC 19977 | MAB_0528c | - | 7e-13 | 37.27% (110) | epoxide hydrolase EphA |
| M. marinum M | MMAR_2050 | - | 2e-16 | 29.58% (240) | hypothetical protein MMAR_2050 |
| M. smegmatis MC2 155 | MSMEG_4707 | - | 7e-90 | 57.30% (274) | non-heme bromoperoxidase BPO-A2 |
| M. thermoresistible (build 8) | TH_3727 | - | 1e-38 | 35.80% (257) | PUTATIVE Chloride peroxidase |
| M. ulcerans Agy99 | MUL_3195 | - | 3e-14 | 26.81% (276) | hydrolase |
| M. vanbaalenii PYR-1 | Mvan_1567 | - | 2e-37 | 35.02% (257) | chloride peroxidase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2561|M.gilvum_PYR-GCK -------------------------------------------MTMITAY
MSMEG_4707|M.smegmatis_MC2_155 -------------------------------------------MAAITAY
MAV_5175|M.avium_104 -------------------------------------------MPDVIAH
TH_3727|M.thermoresistible__bu -------------------------------------------MATITTS
Mvan_1567|M.vanbaalenii_PYR-1 -------------------------------------------MSIFTTT
Mb0569|M.bovis_AF2122/97 --------------------------------------------------
Rv0554|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02269|M.leprae_Br4923 --------------------------------------------------
MMAR_2050|M.marinum_M ------------------MRPTLAAAALAGASGLVGWGGARALARRIERN
MAB_0528c|M.abscessus_ATCC_199 ---------------------------------------MTDAAVDIRER
MUL_3195|M.ulcerans_Agy99 MKYPRRRPHKRRRDVHTAHRYPSRPALARMCGERRSQEIHPVERISALGS
Mflv_2561|M.gilvum_PYR-GCK RGPLRSTDLHVDDSGG------------------DGRPVVLIHGWPLHSD
MSMEG_4707|M.smegmatis_MC2_155 RGLLRSIELHVEDTGG------------------AGRPVVLVHGWPLTGE
MAV_5175|M.avium_104 HGLLKDTRLHVDDTGG------------------PGRPVLLMHPWPLSGQ
TH_3727|M.thermoresistible__bu DG----VEIFYRDWG-------------------SGQPIVFSHGWPLTAD
Mvan_1567|M.vanbaalenii_PYR-1 DG----TDIFYKDWG-------------------SGQPIVFSHGWPLSSD
Mb0569|M.bovis_AF2122/97 -----MINLAYDDNG-------------------TGDPVVFIAGRGGAGR
Rv0554|M.tuberculosis_H37Rv -----MINLAYDDNG-------------------TGDPVVFIAGRGGAGR
MLBr_02269|M.leprae_Br4923 -----MINLAYEDRG-------------------TGEPVVFIAGRGGAGR
MMAR_2050|M.marinum_M PDPFPRERLLAEPQGERVAITRPDGTVLHALVAGRGTPVILVHGYCASLT
MAB_0528c|M.abscessus_ATCC_199 DIATNGVHLRIVEAGEP-----------------GQPAVILSHGFPELAY
MUL_3195|M.ulcerans_Agy99 KPMESAAQPHRIEVGETVCN---DGTVIGHTAAGEGPALALLPGWSLTAQ
* .: :
Mflv_2561|M.gilvum_PYR-GCK SWA-HQVDALRDAGYRVITYDRRGFGRSDKP--LIGYTYESLSDDLSAVL
MSMEG_4707|M.smegmatis_MC2_155 SWG-AQVEALTAAGHRVITYDRRGFGRSDTS--LVGYTYEALSDDLAAVL
MAV_5175|M.avium_104 SWS-AQVPVLHAAGYRVVTYDRRGFGRSDKP--LTGYSYSQLTQDLHTLV
TH_3727|M.thermoresistible__bu DWD-PQMLFFLNAGYRVIAHDRRGHGRSSPV--PDGHDMDHYADDLAALV
Mvan_1567|M.vanbaalenii_PYR-1 DWD-TQMLFFLQRGYRVIAHDRRGHGRSTQT--PDGHDLDHYADDLAELT
Mb0569|M.bovis_AF2122/97 TWHPHQVPAFLAAGYRCITFDNRGIGATEN---AEGFTTQTMVADTAALI
Rv0554|M.tuberculosis_H37Rv TWHPHQVPAFLAAGYRCITFDNRGIGATEN---AEGFTTQTMVADTAALI
MLBr_02269|M.leprae_Br4923 TWQPHQVPAFLAAGYRVITFDNRGIGATEN---TEGFTTQTMVADTAVLI
MMAR_2050|M.marinum_M EWN-FVWDELLARGLRVIAFDQRGHGRSTLG--AEGIGSEPMADDLAAVL
MAB_0528c|M.abscessus_ATCC_199 SWR-HQIPALAAAGYHVIAPDQRGYGRSSMPAHIDDYNIEALSDDLLGIL
MUL_3195|M.ulcerans_Agy99 IFR-HQLAGLSHT-WRVLAIDHRGHGRSSTP--QLGYHIHRLAADLRTVL
: : : :: *.** * : . * :
Mflv_2561|M.gilvum_PYR-GCK EELDLTDVTLVGFSMGGGEVAAYCARKGVERIR----------SVVFASS
MSMEG_4707|M.smegmatis_MC2_155 DELDVRDATLVGFSMGTGEVAAYCARKGTERLR----------SVVLAAP
MAV_5175|M.avium_104 ESLDLRDLTLVGSSMGGGEVARYLSTYGPERVR----------SVVFASS
TH_3727|M.thermoresistible__bu EHLGLRDAVHVGHSTGGGVVVRYLARHGEERTA----------KAVLIAA
Mvan_1567|M.vanbaalenii_PYR-1 AHLDLRDAIHVGHSTGGGEVVRYLGRHGESRVA----------KAALISA
Mb0569|M.bovis_AF2122/97 ETLDIAPARVVGVSMG-AFIAQELMVVAPELVS----------SAVLMAT
Rv0554|M.tuberculosis_H37Rv ETLDIAPARVVGVSMG-AFIAQELMVVAPELVS----------SAVLMAT
MLBr_02269|M.leprae_Br4923 ESLGAVPARIVGVSMG-SFIAQELMVARPELVR----------AAVLMAT
MMAR_2050|M.marinum_M QHFDIRDGVLVGHSMGGFVSIRALLDHGALAQR----------LRAVVLF
MAB_0528c|M.abscessus_ATCC_199 DDVGAGKATFVGHDWG-AVVTWHTALAVPERVSGVVGLSVPFTRRSQVPP
MUL_3195|M.ulcerans_Agy99 QTHQLDQVHLLGHSMGCAVIWSYLELFGTDRLA----------SLLLVDQ
:* . *
Mflv_2561|M.gilvum_PYR-GCK VTPFMSARKDNPEGPLGKLEAARMAASLTTDQDAFFEQFMTDVFSADG--
MSMEG_4707|M.smegmatis_MC2_155 VTPYMLNTADNPEGPLSKTQAAQMAAALTTNSDAFYREMMTGVFSADG--
MAV_5175|M.avium_104 VTPYLLQTTDNPDGPLTMKDAARATASFVKDQDAFYDHQMTEFFSANG--
TH_3727|M.thermoresistible__bu VPPLMVRTDANPGG-LPKSVFDDFQAQLAANRSEFYRALASGPFYGFNRD
Mvan_1567|M.vanbaalenii_PYR-1 VPPLMVRTEDNPEG-TPKEVFDDLQAQLAANRSVFYRSLPAGPFYGFNRP
Mb0569|M.bovis_AF2122/97 RG-----RLDRARQFFNKAEAELYDSGVQLPPTYDARARLLENFSRKT-L
Rv0554|M.tuberculosis_H37Rv RG-----RLDRARQFFNKAEAELYDSGVQLPPTYDARARLLENFSRKT-L
MLBr_02269|M.leprae_Br4923 RG-----RLDRTRQFFHAAEAEFHDSGIQLPSGYNAKVRLLENLSRKT-L
MMAR_2050|M.marinum_M ATWAGRVLDGAPQNRLQIPLLERGILQRLLRSRTIAVLFGAAQCGARP--
MAB_0528c|M.abscessus_ATCC_199 TQAWNKLFGDNFFYILYFQEPGVADADLNRDPATTMRRMMAGMARIDGAT
MUL_3195|M.ulcerans_Agy99 MPCALRNPAWTGAQALEAGATMDPTGLFAFTDRLRADGDDPRPDFVTEVV
Mflv_2561|M.gilvum_PYR-GCK ELQVTEQ----------ERQEALSMCGDADKPATLACMAAFGGTDFREDL
MSMEG_4707|M.smegmatis_MC2_155 VLTISED----------ALQQVLDMCGQASKNAALACMAAFSNTDFREDL
MAV_5175|M.avium_104 QLRVSPA----------TRAEALRLCKQAGKEASLACMAAWANTDFRPDL
TH_3727|M.thermoresistible__bu GVEPSEA----------LIANWWRQGMMGDAKAHYDGIVAFSQTDFTEDL
Mvan_1567|M.vanbaalenii_PYR-1 GVEPQEA----------IIENWWRQGMMGDAYSHYDGIVAFSQTDFTEDL
Mb0569|M.bovis_AF2122/97 NDDVAVG----------DWIAMFSMWPIKSTPGLRCQLDCAPQTNRLPAY
Rv0554|M.tuberculosis_H37Rv NDDVAVG----------DWIAMFSMWPIKSTPGLRCQLDCAPQTNRLPAY
MLBr_02269|M.leprae_Br4923 NDDVAVA----------DWIAMFNMWPIKSTPGLRCQTDVAPQNNRLPAY
MMAR_2050|M.marinum_M -SPAMIS----------VFLEWFHQHLDRHGP-HLPIVRAFSREDRYPRL
MAB_0528c|M.abscessus_ATCC_199 MIAPGPAGFVERMPDPGELPEWLSQDELDHYITEFARTGFTGGLNWYRNF
MUL_3195|M.ulcerans_Agy99 SEGIGAD----------ELAWPVEQGQTLDRRCAADLIFDVATHDWRGLM
:
Mflv_2561|M.gilvum_PYR-GCK PK------------VTVPSLVIHGDSDATVPFEGSGKRTYELLPDGRLHV
MSMEG_4707|M.smegmatis_MC2_155 PR------------VTVPALVIHGDADATTPLQNCGERTHAALPNSRLHV
MAV_5175|M.avium_104 TR------------VSVPALIIHGEGDESVPLAGSARRTHRAIPGSRLCV
TH_3727|M.thermoresistible__bu TK------------ITVPVLVMHGDDDQVVPYANSGPLTAELLRNAKLKT
Mvan_1567|M.vanbaalenii_PYR-1 KK------------ITVPVLVMHSEADQIVPYVASGPKSAALLKNGVLKT
Mb0569|M.bovis_AF2122/97 RN------------IAAPVLVIGFADDVVTPP-YLGREVADALPNGRYLQ
Rv0554|M.tuberculosis_H37Rv RN------------IAAPVLVIGFADDVVTPP-YLGREVADALPNGRYLQ
MLBr_02269|M.leprae_Br4923 RS------------IAAPVLVIGFAEDVVTPP-SLGREVADVLPNGRYLQ
MMAR_2050|M.marinum_M AE------------ISVPAVVMVGSSDRTTPP-SHSHRLAAGIPGARLVT
MAB_0528c|M.abscessus_ATCC_199 DRNWALTERLAGANVVVPSLFIAGAADPVLGFTDHAGSAKYRTDNRGDLL
MUL_3195|M.ulcerans_Agy99 AH------------IGLPTLVLAG--DSVNVPIASQRWMWQQIPGAQFAR
: * :.: * .
Mflv_2561|M.gilvum_PYR-GCK IAG---GPHGIPVSHADEFNAVLLEFLEQDFADGRGR
MSMEG_4707|M.smegmatis_MC2_155 ISG---GPHGIPVSHTEEFNRVLLDFLAEDLAAAR--
MAV_5175|M.avium_104 IAD---GPHGCHISHAQEFNAALLDFLAA--------
TH_3727|M.thermoresistible__bu YQG---FPHGMMTTHAEVVNADILEFLRS--------
Mvan_1567|M.vanbaalenii_PYR-1 YKD---FPHGMPTTHADVVNADLLEFLKG--------
Mb0569|M.bovis_AF2122/97 IPD---AGHLGFFERPEAVNTAMLKFFASVKA-----
Rv0554|M.tuberculosis_H37Rv IPD---AGHLGFFERPEAVNTAMLKFFASVKA-----
MLBr_02269|M.leprae_Br4923 IPD---AGHLGFFERPEAVNAAALQFFAGVKGEWP--
MMAR_2050|M.marinum_M VPG---AGHLLNWEAVDELAEVVESFAAQR-------
MAB_0528c|M.abscessus_ATCC_199 IDG---AGHWIQQERPLEVNAALLAFLREVVH-----
MUL_3195|M.ulcerans_Agy99 VPGRRGGTHFPFLENPQTFNDVVSQHLCAHRPG----
. * . .