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SEVVCTLDGAIGRITLNRPDRMNAINIAIADKLKVAVRTYGNHPDVHAIVIRGAGGNFCAGGDFTEVERL RAAGPAALRALFKTFHAACQAITDVDVPVVVAVEGVAMAGGFELMQAADIVLVSDNARIADNHINFGMIP GGGSTVRLPRNVGRQVALALMLSGERLSGADAVARGLAYRSFPAADFEDSVETFVRQLAERDRGAATRIK RLVLDGLHRPIEEAVASETDAVVEWICGPAGSDGVTAFQNREVAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5087 | - | - | 100% (256) | enoyl-CoA hydratase/isomerase family protein |
| M. avium 104 | MAV_5086 | - | 3e-28 | 33.33% (246) | enoyl-CoA hydratase |
| M. avium 104 | MAV_1939 | - | 2e-27 | 31.20% (250) | enoyl-CoA hydratase/isomerase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1099c | echA8 | 2e-27 | 29.88% (241) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2125 | - | 8e-25 | 25.39% (256) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv1070c | echA8 | 2e-27 | 29.88% (241) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 1e-25 | 29.41% (238) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_4570c | - | 1e-27 | 32.40% (250) | enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4396 | echA8 | 5e-28 | 29.88% (241) | enoyl-CoA hydratase EchA8 |
| M. smegmatis MC2 155 | MSMEG_6777 | - | 3e-30 | 32.35% (238) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_4445 | - | 1e-78 | 58.40% (250) | PUTATIVE enoyl-CoA hydratase/isomerase family protein |
| M. ulcerans Agy99 | MUL_0210 | echA8 | 3e-28 | 29.88% (241) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_1985 | - | 5e-27 | 32.39% (247) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5087|M.avium_104 ---------MSEVVCTLDGA-IGRITLNRPDRMNAINIAIADKLKVAVRT
TH_4445|M.thermoresistible__bu ----------VNVLRAVDSG-VGRITLNRPDRMNAITVGLATELENAITE
MMAR_4396|M.marinum_M -------MSYETILVERDQR-VGIITLNRPQALNALNSQVMNEVTSAAAE
MUL_0210|M.ulcerans_Agy99 -------MSYETILVERDQR-VGIITLNRPQALNALNSQVMNEVTSAAAE
Mb1099c|M.bovis_AF2122/97 -------MTYETILVERDQR-VGIITLNRPQALNALNSQVMNEVTSAATE
Rv1070c|M.tuberculosis_H37Rv -------MTYETILVERDQR-VGIITLNRPQALNALNSQVMNEVTSAATE
MLBr_02402|M.leprae_Br4923 -------MKYDTILVDGYQR-VGIITLNRPQALNALNSQMMNEITNAAKE
MSMEG_6777|M.smegmatis_MC2_155 ------MTTYTTIATSRPVAGVGLIRLDRPDALNALNQTLEAEVLDAARD
Mflv_2125|M.gilvum_PYR-GCK MTATDAYQGIDHLTASLDGS-VLTVTLNRPESLNSLTAPMLETFAVTLER
MAB_4570c|M.abscessus_ATCC_199 MSLDES---VGAPDVAVDGG-IMRVTFTRPDRMNALNGPATSGLIEALES
Mvan_1985|M.vanbaalenii_PYR-1 MRDDAG-----AVRVVRDDA-VLRITLDRPTRRNSLSHAMIDDLVGTLTS
: : : ** *::. . :
MAV_5087|M.avium_104 YGNHPDVHAIVIRG--AGGNFCAGGDFTEVERLRAAGPA--ALRALFKTF
TH_4445|M.thermoresistible__bu LSADPAVNVIVIRG--AGGNFSAGGDFDEVERLRAEGGS--ALAALFTKF
MMAR_4396|M.marinum_M LDNDPGIGAIIITG--SAKAFAAGADIKEMADLTFS-------EAFDADF
MUL_0210|M.ulcerans_Agy99 LDNDPGIGAIIITG--SAKAFAAGADIKEMADLTFS-------EAFDADF
Mb1099c|M.bovis_AF2122/97 LDDDPDIGAIIITG--SAKAFAAGADIKEMADLTFA-------DAFTADF
Rv1070c|M.tuberculosis_H37Rv LDDDPDIGAIIITG--SAKAFAAGADIKEMADLTFA-------DAFTADF
MLBr_02402|M.leprae_Br4923 LDIDPDVGAILITG--SPKVFAAGADIKEMASLTFT-------DAFDADF
MSMEG_6777|M.smegmatis_MC2_155 FDADLEIGAIVVTG--SERAFAAGADIAEMVTLTPH-------QARERNL
Mflv_2125|M.gilvum_PYR-GCK AATDPRVRVVRIGG--AGRGFCSGAGISE--EDHANPGAAGSPNDVLDAA
MAB_4570c|M.abscessus_ATCC_199 IPGRDDVRVVVISGGAPGSAFSAGADVTELAAGSADLTPLQAAELTMDNA
Mvan_1985|M.vanbaalenii_PYR-1 AASDDSVRAIHLTG--AGDDFCSGADWVTTNSSDRKPRPGNLVRRIPHAA
: .: : * . *.:*..
MAV_5087|M.avium_104 HAACQAITDVDVPVVVAVEGVAMAGGFELMQAADIVLVSDNARIADNHIN
TH_4445|M.thermoresistible__bu RAACGAIAAVDVPVIAAVQGVAAAGGFELMQACDIVLVSTDARIADSHVK
MMAR_4396|M.marinum_M FAAWGKLAAVRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIK
MUL_0210|M.ulcerans_Agy99 FAAWGKLAAVRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIK
Mb1099c|M.bovis_AF2122/97 FATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIK
Rv1070c|M.tuberculosis_H37Rv FATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIK
MLBr_02402|M.leprae_Br4923 FSAWGKLAAVRTPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIK
MSMEG_6777|M.smegmatis_MC2_155 LSGWDSLTQVRKPIVAAVAGYALGGGCELAMLCDLVIAADTARFGQPEIT
Mflv_2125|M.gilvum_PYR-GCK NRCIRAIANLPQPAVAVVQGAAAGVGVSLALACDVVLASEKSFFMLAFTK
MAB_4570c|M.abscessus_ATCC_199 ERLVRAVLNCPVPTIAEVTGVAAGIGASVGLACDLIYAADTAFFLLAFAN
Mvan_1985|M.vanbaalenii_PYR-1 NRVVELVATIQLPVVCTVRGWAVGLGANLALAADFTLATPEANLWEPFID
: * : * * * . * .: .*. .: : :
MAV_5087|M.avium_104 FGMIPGGGSTVRLPRNVGRQVALALMLSGERLSGADAVARGLAYRSFPAA
TH_4445|M.thermoresistible__bu FGMVPGGGSSARLPRLVGRQQAMGLLLSGDRITGAEAVALGLAYRAFSES
MMAR_4396|M.marinum_M LGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPAD
MUL_0210|M.ulcerans_Agy99 LGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPAD
Mb1099c|M.bovis_AF2122/97 LGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPAD
Rv1070c|M.tuberculosis_H37Rv LGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPAD
MLBr_02402|M.leprae_Br4923 LGVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLAD
MSMEG_6777|M.smegmatis_MC2_155 LGILPGLGGTQRLTRAVGKAKAMDLCLTGRSLTAEEAERVGLVSRIVPAA
Mflv_2125|M.gilvum_PYR-GCK IGLMPDGAASALIAAAVGRIRAMRMALLAERITADEAYAWGLVSQVYPAD
MAB_4570c|M.abscessus_ATCC_199 IGLMPDGGSSALVSASIGRVKANAMALLAQPLSATDAFAAGLVNEALPGD
Mvan_1985|M.vanbaalenii_PYR-1 RGFSPDSGSTWLLPRLAGVTRAKRMLLLGEKVTGADAADWGLIHQAVPAD
*. *. ..: :. * * : * . : . :* ** .
MAV_5087|M.avium_104 DFEDSVETFVRQLAERDRGAATRIKRLVLDGLHRPIEEAVASETDAVVEW
TH_4445|M.thermoresistible__bu EFDYAVTDFANQMAQRNRQSVTTIKRLVNTGMNHPLDEALDAEIETVVRH
MMAR_4396|M.marinum_M DLLTEAKAVATTISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHSA
MUL_0210|M.ulcerans_Agy99 DLLTEAKAVATTISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHSA
Mb1099c|M.bovis_AF2122/97 DLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSA
Rv1070c|M.tuberculosis_H37Rv DLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSA
MLBr_02402|M.leprae_Br4923 DLLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHST
MSMEG_6777|M.smegmatis_MC2_155 DLLDEALAVAQRIARMSRPAGRAVKDAINEAFERPLSAGMRYERDAFYAM
Mflv_2125|M.gilvum_PYR-GCK SLEAEAASVIETLATGPAVALRLTKDAINGATLTEVENALERETKGQLRL
MAB_4570c|M.abscessus_ATCC_199 QLRERVDKTARRLAHGSRRAMQLTKEAMNAVSLKLFDEAIARERDGQIEL
Mvan_1985|M.vanbaalenii_PYR-1 EIDAAAEELVTRLASGPTVAIGLAKQAINYGMHATLPQSMAHELASLELA
.: . :: : * : . .: *
MAV_5087|M.avium_104 ICGPAGSDGVTAFQNR---EVAR-
TH_4445|M.thermoresistible__bu ILGDAGAGSVEQFATRKDREVRG-
MMAR_4396|M.marinum_M FATADQSEGMAAFIEKRPPNFTHR
MUL_0210|M.ulcerans_Agy99 FATADQSEGMAAFIEKRPPNFTHR
Mb1099c|M.bovis_AF2122/97 FATEDQSEGMAAFIEKRAPQFTHR
Rv1070c|M.tuberculosis_H37Rv FATEDQSEGMAAFIEKRAPQFTHR
MLBr_02402|M.leprae_Br4923 FVTDDQSEGMAAFIEKRAPQFTHR
MSMEG_6777|M.smegmatis_MC2_155 FDTHDQTEGMTAFLEKRTPEFTDR
Mflv_2125|M.gilvum_PYR-GCK LHSDDFREGTKAFQQRRAAKFTDV
MAB_4570c|M.abscessus_ATCC_199 LISPDAHEGFAAFLEGRRPNFS--
Mvan_1985|M.vanbaalenii_PYR-1 CRTADFKEGLAAFRARRAPDFEGR
. * ..