For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_4396 (echA8)

annotation: enoyl-CoA hydratase EchA8
coordinates: 5405260 - 5406033
length: 257

MSYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAAAELDNDPGIGAIIITGSAKAFAAGADIKEM
ADLTFSEAFDADFFAAWGKLAAVRTPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIKLGVLPGM
GGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLTEAKAVATTISQMSRSAARMAKEA
VNRTFEATLAEGLLYERRLIHSAFATADQSEGMAAFIEKRPPNFTHR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_4396echA8-100% (257)enoyl-CoA hydratase EchA8
M. marinum MMMAR_5002echA191e-3536.72% (256) enoyl-CoA hydratase EchA19
M. marinum MMMAR_1662echA173e-3536.97% (238) enoyl-CoA hydratase EchA17

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1099cechA81e-12991.05% (257) enoyl-CoA hydratase
M. gilvum PYR-GCKMflv_2036-1e-11781.32% (257) enoyl-CoA hydratase
M. tuberculosis H37RvRv1070cechA81e-12991.05% (257) enoyl-CoA hydratase
M. leprae Br4923MLBr_02402-1e-12386.77% (257) enoyl-CoA hydratase
M. abscessus ATCC 19977MAB_1185c-1e-11379.69% (256) enoyl-CoA hydratase
M. avium 104MAV_1195-1e-12688.67% (256) enoyl-CoA hydratase
M. smegmatis MC2 155MSMEG_5277-1e-11481.57% (255) enoyl-CoA hydratase
M. thermoresistible (build 8)TH_4102-1e-11984.38% (256) PUTATIVE short chain enoyl-CoA hydratase
M. ulcerans Agy99MUL_0210echA81e-140100.00% (257) enoyl-CoA hydratase
M. vanbaalenii PYR-1Mvan_4681-1e-11380.08% (256) enoyl-CoA hydratase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2036|M.gilvum_PYR-GCK          ------MTFETILVDRDDRVATITLNRPKALNALNTQVMNEVTTAAAELD
Mvan_4681|M.vanbaalenii_PYR-1       ---MGSQNFETIIVERDDRVATITLNRPKALNALNSQVMDEVTTAAAELD
MSMEG_5277|M.smegmatis_MC2_155      -----MSDFETILVTRTDRVATIQLNRPKALNALNSQVMTEVTAAAAELD
TH_4102|M.thermoresistible__bu      ---MSAKNYETILVTREDRVGIITLNRPKALNALNSQVMTEVTDAAAEFD
Mb1099c|M.bovis_AF2122/97           ------MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELD
Rv1070c|M.tuberculosis_H37Rv        ------MTYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAATELD
MMAR_4396|M.marinum_M               ------MSYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAAAELD
MUL_0210|M.ulcerans_Agy99           ------MSYETILVERDQRVGIITLNRPQALNALNSQVMNEVTSAAAELD
MLBr_02402|M.leprae_Br4923          ------MKYDTILVDGYQRVGIITLNRPQALNALNSQMMNEITNAAKELD
MAV_1195|M.avium_104                MTDSTDRTFETILVEREERVGIITLNRPKALNALNTQVMNEVTTAATDFD
MAB_1185c|M.abscessus_ATCC_199      ---MTSHNFETILTERIDRVAVITLNRPKALNALNSQVMNEVTTAAAEFD
                                            ::**:.   :**. * ****:******:*:* *:* ** ::*

Mflv_2036|M.gilvum_PYR-GCK          AEPGVGAIIVTGSERAFAAGADIKEMASLSFADVFSSDFFAAWGKFAATR
Mvan_4681|M.vanbaalenii_PYR-1       ADAGVGAIILTGSEKAFAAGADIKEMAGLSFADVFSSDFFAGWGKFAATR
MSMEG_5277|M.smegmatis_MC2_155      KDPGVGAIIVTGNEKAFAAGADIKEMADLSFAEVFEADFFELWSKFAATR
TH_4102|M.thermoresistible__bu      SDPGIGAIIVTGNEKAFAAGADIKEMADLEFADVFAADFFAPWSKFAATR
Mb1099c|M.bovis_AF2122/97           DDPDIGAIIITGSAKAFAAGADIKEMADLTFADAFTADFFATWGKLAAVR
Rv1070c|M.tuberculosis_H37Rv        DDPDIGAIIITGSAKAFAAGADIKEMADLTFADAFTADFFATWGKLAAVR
MMAR_4396|M.marinum_M               NDPGIGAIIITGSAKAFAAGADIKEMADLTFSEAFDADFFAAWGKLAAVR
MUL_0210|M.ulcerans_Agy99           NDPGIGAIIITGSAKAFAAGADIKEMADLTFSEAFDADFFAAWGKLAAVR
MLBr_02402|M.leprae_Br4923          IDPDVGAILITGSPKVFAAGADIKEMASLTFTDAFDADFFSAWGKLAAVR
MAV_1195|M.avium_104                ADPGIGAIIITGSAKAFAAGADIKEMAELTFADAYGADFFAPWGKLAALR
MAB_1185c|M.abscessus_ATCC_199      ADHGIGAIIITGSEKAFAAGADIKEMSEQSFSDMFGSDFFSAWGKLGAVR
                                     : .:***::**. :.**********:   *:: : :***  *.*:.* *

Mflv_2036|M.gilvum_PYR-GCK          TPTIAAVAGYALGGGCELAMMCDILIAADTAKFGQPEIKLGVLPGMGGSQ
Mvan_4681|M.vanbaalenii_PYR-1       TPTIAAVAGYALGGGCELAMMCDILIAADTAKFGQPEIKLGVLPGMGGSQ
MSMEG_5277|M.smegmatis_MC2_155      TPTIAAVAGYALGGGCELAMMCDILIAADTAKFGQPEIKLGVLPGMGGSQ
TH_4102|M.thermoresistible__bu      TPTIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGMGGSQ
Mb1099c|M.bovis_AF2122/97           TPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGGSQ
Rv1070c|M.tuberculosis_H37Rv        TPTIAAVAGYALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGGSQ
MMAR_4396|M.marinum_M               TPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIKLGVLPGMGGSQ
MUL_0210|M.ulcerans_Agy99           TPTIAAVAGYALGGGCEVAMMCDLIIAADTAKFGQPEIKLGVLPGMGGSQ
MLBr_02402|M.leprae_Br4923          TPMIAAVAGYALGGGCELAMMCDLLIAADTAKFGQPEIKLGVLPGMGGSQ
MAV_1195|M.avium_104                TPTIAAVAGHALGGGCELAMMCDVLIAADTAKFGQPEIKLGVLPGMGGSQ
MAB_1185c|M.abscessus_ATCC_199      TPTIAAVSGYALGGGCELAMMCDVIIAAENATFGQPEIKLGVLPGMGGSQ
                                    ** ****:*:*******:*****::***:.*.******************

Mflv_2036|M.gilvum_PYR-GCK          RLTRAIGKAKAMDLILTGRNMDAEEAERAGLVSRVVPADSLLSEAKAVAQ
Mvan_4681|M.vanbaalenii_PYR-1       RLTRAIGKAKAMDLILTGRNMGAEEAERAGLVSRVVPADTLLEEARSVAK
MSMEG_5277|M.smegmatis_MC2_155      RLTRAIGKAKAMDLILTGRTIDAAEAERAGLVSRLVPADTLIDEALAVAQ
TH_4102|M.thermoresistible__bu      RLTRAIGKAKAMDLILTGRTIDAEEAERSGLVSRVVPADKLLDEAKETAA
Mb1099c|M.bovis_AF2122/97           RLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARATAT
Rv1070c|M.tuberculosis_H37Rv        RLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARATAT
MMAR_4396|M.marinum_M               RLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLTEAKAVAT
MUL_0210|M.ulcerans_Agy99           RLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLTEAKAVAT
MLBr_02402|M.leprae_Br4923          RLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADDLLPEAKAVAT
MAV_1195|M.avium_104                RLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADDLLTEAKKVAT
MAB_1185c|M.abscessus_ATCC_199      RLTRAIGKAKAMDMILTGRNMDAAEAERSGLVSRVVATESLLDEAKAVAK
                                    *************:*****.:.* ****:*****:* :: *: **  .* 

Mflv_2036|M.gilvum_PYR-GCK          TIAGMSLSASRMAKEAVDRAFETTLSEGLLYERRLFHSAFATDDQTEGMN
Mvan_4681|M.vanbaalenii_PYR-1       TIAGMSLSASRMAKEAVDRAFETTLTEGLLYERRLFHSAFATDDQTEGMN
MSMEG_5277|M.smegmatis_MC2_155      TIAGMSLSASRMAKEAVNRAFETSLTEGLLYERRLFHSAFATADQKEGMA
TH_4102|M.thermoresistible__bu      TIAAMSLSAARMAKEAVNRAFETSLAEGLLFERRVFHSAFATADQSEGMA
Mb1099c|M.bovis_AF2122/97           TISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEGMA
Rv1070c|M.tuberculosis_H37Rv        TISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATEDQSEGMA
MMAR_4396|M.marinum_M               TISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHSAFATADQSEGMA
MUL_0210|M.ulcerans_Agy99           TISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHSAFATADQSEGMA
MLBr_02402|M.leprae_Br4923          TISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTFVTDDQSEGMA
MAV_1195|M.avium_104                TISQMSRSAARMAKEAVNRAFETTLAEGLLYERRLFHSTFATADQSEGMA
MAB_1185c|M.abscessus_ATCC_199      TISEMSLSASMMAKEAVNRAFESSLAEGLLFERRIFHSAFGTADQSEGMA
                                    **: ** **: ******:*:**::*:****.***::**:* * **.*** 

Mflv_2036|M.gilvum_PYR-GCK          AFSEKRSPNFTHR
Mvan_4681|M.vanbaalenii_PYR-1       AFTEKRSPNFTHR
MSMEG_5277|M.smegmatis_MC2_155      AFAEKRAANFTHR
TH_4102|M.thermoresistible__bu      AFTEKRPPKFTHR
Mb1099c|M.bovis_AF2122/97           AFIEKRAPQFTHR
Rv1070c|M.tuberculosis_H37Rv        AFIEKRAPQFTHR
MMAR_4396|M.marinum_M               AFIEKRPPNFTHR
MUL_0210|M.ulcerans_Agy99           AFIEKRPPNFTHR
MLBr_02402|M.leprae_Br4923          AFIEKRAPQFTHR
MAV_1195|M.avium_104                AFVEKRAPNFTHR
MAB_1185c|M.abscessus_ATCC_199      AFVEKRPANFIHR
                                    ** ***..:* **