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TTSLDAPVLREVDADGVARVRLNRPQTSNGLNVETLKALHDAVLTCHADPTVKVVLLSGAGRNFCAGGDV HTFESKGADLPDYLREATAWLQLATAALIQLRAPVVTAVQGFAAGGGGLGLVCASDVVLAGRSAKFFSGA VRVGMAPDGGSSVTLTQLVGLRQALRILLTNPTLGAEEAAAIGLITDVVDDDALTEEAERIAKTLAAMPP KALSATKRLVWSGVGVPVESRLAEEARIVSELSGTADALEGLRAVIERRPPRFTGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5086 | - | - | 100% (267) | enoyl-CoA hydratase |
| M. avium 104 | MAV_5085 | - | 6e-33 | 36.00% (250) | enoyl-CoA hydratase |
| M. avium 104 | MAV_1195 | - | 4e-31 | 33.33% (255) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1173c | echA11 | 4e-30 | 34.92% (252) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_2902 | - | 5e-40 | 36.69% (248) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1141c | echA11 | 4e-30 | 34.92% (252) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02402 | - | 3e-30 | 33.85% (257) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_0905 | - | 6e-32 | 32.96% (270) | putative enoyl-CoA hydratase/isomerase |
| M. marinum M | MMAR_4396 | echA8 | 2e-31 | 32.93% (249) | enoyl-CoA hydratase EchA8 |
| M. smegmatis MC2 155 | MSMEG_4299 | - | 6e-37 | 37.05% (251) | enoyl-CoA hydratase/isomerase |
| M. thermoresistible (build 8) | TH_3726 | - | 1e-118 | 80.45% (266) | PUTATIVE probable enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_0210 | echA8 | 1e-31 | 32.93% (249) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_3603 | - | 3e-38 | 36.84% (247) | enoyl-CoA hydratase/isomerase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_5086|M.avium_104 -----MTTSLDAPVLREVDADGVARVRLNRPQTSNGLNVETLKALHDAVL
TH_3726|M.thermoresistible__bu -----MTTSIESPVILSTGEDGIARLRLNRPEASNGLTVELLKALHEAVL
Mflv_2902|M.gilvum_PYR-GCK -----MTD--YQTITLEQSGP-VARITLNRPEAANGMNGTMTRELADAAA
Mvan_3603|M.vanbaalenii_PYR-1 -----MTE--YQTITFEQAGV-VARITLNRPDAANGMNGTMTRELADAAA
MSMEG_4299|M.smegmatis_MC2_155 -----MTEISYEAIAFEQSGP-ITRITLNRPDAANGMNDTMTRELADAAR
MMAR_4396|M.marinum_M --------MSYETILVERDQR-VGIITLNRPQALNALNSQVMNEVTSAAA
MUL_0210|M.ulcerans_Agy99 --------MSYETILVERDQR-VGIITLNRPQALNALNSQVMNEVTSAAA
MLBr_02402|M.leprae_Br4923 --------MKYDTILVDGYQR-VGIITLNRPQALNALNSQMMNEITNAAK
MAB_0905|M.abscessus_ATCC_1997 -----MTQTAPAAVAYSVNHAGVAAIVLDRPEASNALDRTMKTELLQALL
Mb1173c|M.bovis_AF2122/97 MPDSGIAALTPVTGLNVTLTDRVLSVRINRPSSLNSLTVPILTGIADTLE
Rv1141c|M.tuberculosis_H37Rv MPDSGIAALTPVTGLNVTLTDRVLSVRINRPSSLNSLTVPILTGIADTLE
. : : ::**.: *.: : .:
MAV_5086|M.avium_104 TCHADPTVKVVLLSGAGRNFCAGGDVHTFESKGAD-LPDYLREATAWLQL
TH_3726|M.thermoresistible__bu ACHADPAVKIVLLSGEGRNFCAGGDVKTFESKGES-LPEYLREATAWLQL
Mflv_2902|M.gilvum_PYR-GCK RCDT-PATKVVVLTGAGRFFCAGGDLKDFASAPSR--GQHVKGVADDLHR
Mvan_3603|M.vanbaalenii_PYR-1 RCDT-AATKVVVITGAGRFFCAGGDLKDFASAPSR--GRHVKGVADDLHR
MSMEG_4299|M.smegmatis_MC2_155 RADT-SGAKVVVLTGSGRFFSAGGDLKAFSTAPSR--GAFIKGVADDLHR
MMAR_4396|M.marinum_M ELDNDPGIGAIIITGSAKAFAAGADIKEMADLT------FSEAFDADFFA
MUL_0210|M.ulcerans_Agy99 ELDNDPGIGAIIITGSAKAFAAGADIKEMADLT------FSEAFDADFFA
MLBr_02402|M.leprae_Br4923 ELDIDPDVGAILITGSPKVFAAGADIKEMASLT------FTDAFDADFFS
MAB_0905|M.abscessus_ATCC_1997 AAGGDPAVRAVVMSAAGKNFCVGQDLAEHVEALRDDPAHAMDTVREHYNP
Mb1173c|M.bovis_AF2122/97 RAAADPVVKVVRLGGVGRGFSSGVSMSVDDVWGGG----PPTAIVEEANR
Rv1141c|M.tuberculosis_H37Rv RAAADPVVKVVRLGGVGRGFSSGVSMSVDDVWGGG----PPTAIVEEANR
. : : . : *. * .:
MAV_5086|M.avium_104 ATAALIQLRAPVVTAVQGFAAGGGGLGLVCASDVVLAGRSAKFFSGAVRV
TH_3726|M.thermoresistible__bu ATAALIQLRVPVVTAVQGYVAGGGGLGLVCASDFVIAARSAKFFSGAVRV
Mflv_2902|M.gilvum_PYR-GCK AISSFARMDAVVITVVNGTAAGAG-FSLAVSGDLVLAAESASFTMAYTKV
Mvan_3603|M.vanbaalenii_PYR-1 AISTFARMDAVVITAVNGTAAGAG-FSLAVSGDLVLAAESASFTMAYTRV
MSMEG_4299|M.smegmatis_MC2_155 AISSFARMDAVLITAVNGTAAGAG-FSIAVTGDLVLAAESASFTMAYTKV
MMAR_4396|M.marinum_M AWGKLAAVRTPTIAAVAGYALGGG-CEVAMMCDLIIAADTAKFGQPEIKL
MUL_0210|M.ulcerans_Agy99 AWGKLAAVRTPTIAAVAGYALGGG-CEVAMMCDLIIAADTAKFGQPEIKL
MLBr_02402|M.leprae_Br4923 AWGKLAAVRTPMIAAVAGYALGGG-CELAMMCDLLIAADTAKFGQPEIKL
MAB_0905|M.abscessus_ATCC_1997 VLEALDAIKVPVVVAINGACVGAG-LGLALGADIRIAGQRAKFGTAFTGI
Mb1173c|M.bovis_AF2122/97 AVRAVAALPHPVVAVVQGPAVGVA-VSLALACDFILASDSAFFMLANTKV
Rv1141c|M.tuberculosis_H37Rv AVRAVAALPHPVVAVVQGPAVGVA-VSLALACDFILASDSAFFMLANTKV
. . : :..: * * . :. *. :*. * * :
MAV_5086|M.avium_104 GMAPDGGSSVTLTQLVGLRQALRILLTNPTLGAEEAAAIGLITDVVDDDA
TH_3726|M.thermoresistible__bu GMAPDGGASVTLTQLVGLRQALRILLANPTLSAEEAAGIGLITEVVDDVE
Mflv_2902|M.gilvum_PYR-GCK GLSPDGSASYYLPRLIGIAKTKQLMLTNRVLSADEASRWGLVTEVVADDE
Mvan_3603|M.vanbaalenii_PYR-1 GLSPDGSASYHLPRLIGIAKTKQLMLTNRTLSAQEALQWGLVGEVVADDR
MSMEG_4299|M.smegmatis_MC2_155 GLSPDGSASYYLPRLVGMRRAQELMLTNRTLSATEAYEWGLVTEVVPDAD
MMAR_4396|M.marinum_M GVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADD
MUL_0210|M.ulcerans_Agy99 GVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVPADD
MLBr_02402|M.leprae_Br4923 GVLPGMGGSQRLTRAIGKAKAMDLILTGRTIDAAEAERSGLVSRVVLADD
MAB_0905|M.abscessus_ATCC_1997 GLAADSALSASLPRLIGASRATAMFLLGDTIDAPTAHTWGLVHEVVDEGS
Mb1173c|M.bovis_AF2122/97 ALMPDGGASALVAAATGRIRAMRLALLAEQLPAREALAWGLISAVYPDSD
Rv1141c|M.tuberculosis_H37Rv ALMPDGGASALVAAATGRIRAMRLALLAEQLPAREALAWGLISAVYPDSD
.: .. . * :. * :: : * : * * **: *
MAV_5086|M.avium_104 LTEEAERIAKTLAAMPPKALSATKRLVWSGVGVPVESRLAEEARIVSELS
TH_3726|M.thermoresistible__bu LTARAEALAAELTALPPLALSATKRLVWSGVGQSVAERLAEEARTVSELS
Mflv_2902|M.gilvum_PYR-GCK LAARADALAGQMAATAAGSNGGVKALLLDTFSNGLEQQMELEGRLIAQRA
Mvan_3603|M.vanbaalenii_PYR-1 LQARADELAEQMAETSAGSNGGVKALLSDTFANGLEQQMELEGRLIAARA
MSMEG_4299|M.smegmatis_MC2_155 LADRATKLAEQVAAGSAGSNGAVKSLLLSSLKNSLEEQMEAEGRFIAARA
MMAR_4396|M.marinum_M LLTEAKAVATTISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHSAF
MUL_0210|M.ulcerans_Agy99 LLTEAKAVATTISQMSRSAARMAKEAVNRTFEATLAEGLLYERRLIHSAF
MLBr_02402|M.leprae_Br4923 LLPEAKAVATTISQMSRSATRMAKEAVNRSFESTLAEGLLHERRLFHSTF
MAB_0905|M.abscessus_ATCC_1997 PADVANSVAGRLAGGPTAAFSEVKELLRRNAVAPLGDVLEREASAQQRLG
Mb1173c|M.bovis_AF2122/97 FEAEVDKVISRLLAGPALAFAQAKNAINAAALTELEPTFARELDGQEVLL
Rv1141c|M.tuberculosis_H37Rv FEAEVDKVISRLLAGPALAFAQAKNAINAAALTELEPTFARELDGQEVLL
. : : . : .* : : : *
MAV_5086|M.avium_104 GTADALEGLRAVIERRPPRFTGA---
TH_3726|M.thermoresistible__bu GTADSLEGLRAVIERRPPRFTGR---
Mflv_2902|M.gilvum_PYR-GCK ESADGREGVDAFLAKRKPEFSPGG--
Mvan_3603|M.vanbaalenii_PYR-1 ESADGREGVDAFLAKRRPKFGAQSAG
MSMEG_4299|M.smegmatis_MC2_155 DSADGREGVDAFLGKRRPEFA-----
MMAR_4396|M.marinum_M ATADQSEGMAAFIEKRPPNFTHR---
MUL_0210|M.ulcerans_Agy99 ATADQSEGMAAFIEKRPPNFTHR---
MLBr_02402|M.leprae_Br4923 VTDDQSEGMAAFIEKRAPQFTHR---
MAB_0905|M.abscessus_ATCC_1997 ASRDHSAAVEAFLAKDKPVFVGR---
Mb1173c|M.bovis_AF2122/97 RTHDFAEGAAAFLQRRTPNFTGS---
Rv1141c|M.tuberculosis_H37Rv RTHDFAEGAAAFLQRRTPNFTGS---
: * . *.: : * *