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LSERGYAGLRLTDVAAAAELQAPAIYYYFSSRDELIEEVMWSGLADMREHVAAVLEDVPDGTPAMDRLLI AAEAHLRHELEVSDYTTASIRNAGQIPPPIRKRQLLEEARYGELWRKLINDVACEGLLWPQLDLHIAQML VLGALNWAVEWWNPRRGSIESVVRNAQLIIRHGLTDGATA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_5066 | - | - | 100% (181) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_5091 | - | 1e-45 | 61.24% (129) | TetR family protein transcriptional regulator, putative |
| M. avium 104 | MAV_1669 | - | 6e-09 | 24.49% (147) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2534 | - | 5e-08 | 25.85% (147) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2551 | - | 2e-09 | 25.00% (116) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2506 | - | 5e-08 | 25.85% (147) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0901c | - | 7e-09 | 22.64% (159) | TetR family transcriptional regulator |
| M. marinum M | MMAR_3853 | - | 9e-09 | 26.72% (116) | putative regulatory protein |
| M. smegmatis MC2 155 | MSMEG_4718 | - | 1e-09 | 21.55% (181) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3291 | - | 1e-71 | 69.89% (176) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_3785 | - | 6e-09 | 26.72% (116) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4092 | - | 3e-08 | 27.97% (118) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2534|M.bovis_AF2122/97 MTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLED
Rv2506|M.tuberculosis_H37Rv MTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLED
MMAR_3853|M.marinum_M MAASAPDEQTATP---NRRSQQKSDRRLQLLSAAERLFAERGFLAVRLED
MUL_3785|M.ulcerans_Agy99 MAASAPDEQTATP---NRRSQQKSDRRLQLLSAAERLFAERGFLAVRLED
MSMEG_4718|M.smegmatis_MC2_155 MSSVT------------RRSQAKSDRRSQLIAAAERLVAERGYLAVRLED
Mflv_2551|M.gilvum_PYR-GCK MAPTEIS---------SPRSRAKSDRRDQLVAAAERLFAEHGYLAVRLED
Mvan_4092|M.vanbaalenii_PYR-1 MTTTDAT---------SPRSRAKSDRRGQLIGAAERLIAEHGYLAVRLED
MAV_5066|M.avium_104 ------------------------------------MLSERGYAGLRLTD
TH_3291|M.thermoresistible__bu --------------VNDEQESKSAATRARILDAAAHVLSVRGYAGLRLTD
MAB_0901c|M.abscessus_ATCC_199 MTTPRTR--------PSRQVGRPGYDLDSLLAVAVSVFNQRGYDGTSMEH
:. :*: . : .
Mb2534|M.bovis_AF2122/97 IGAAAGVSGPAIYRHFPNKESLLVELLVG--VSARLLAGARDVTT-RSAN
Rv2506|M.tuberculosis_H37Rv IGAAAGVSGPAIYRHFPNKESLLVELLVG--VSARLLAGARDVTT-RSAN
MMAR_3853|M.marinum_M IGAAAGISGPAIYRHFPNKESLLVELLVG--ISSRLLAGARQVTT-NSND
MUL_3785|M.ulcerans_Agy99 IGAAAGISGPAIYRHFPNKESLLVELLVG--ISSRLLAGARQVTT-NSND
MSMEG_4718|M.smegmatis_MC2_155 IGAAVGVSGPAIYRHFPNKEAMLVELLVG--ISTRLLDGAREVVE-THDD
Mflv_2551|M.gilvum_PYR-GCK IGSAAGISGPAVYRHFPNKEALLVELLVG--ISTRLLAGATDVVG-ADDD
Mvan_4092|M.vanbaalenii_PYR-1 IGAAAGISGPAIYRHFPNKEALLVELLVG--ISTRLLAGAVEVVDRAGDD
MAV_5066|M.avium_104 VAAAAELQAPAIYYYFSSRDELIEEVMWSGLADMREHVAAVLEDVPDGTP
TH_3291|M.thermoresistible__bu VAARADIQAPAIYYYYPSREALIEEVMWVGIADTRDQVVAALDALPDGTP
MAB_0901c|M.abscessus_ATCC_199 LSTRLGISKSSIYHHVSGKEELLRLAVDR---ALDALFAATEAPDTTTGP
:.: :. .::* : ..:: :: : *
Mb2534|M.bovis_AF2122/97 LAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKAQRQYVE
Rv2506|M.tuberculosis_H37Rv LAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKAQRQYVE
MMAR_3853|M.marinum_M AAAALDGLIDFHLDFALGEPDLIRIQDRDLGHLPAAAERQVRKAQRQYVE
MUL_3785|M.ulcerans_Agy99 AAAALDGLIDFHLDFALGEPDLIRIQDRDLGHLPAAAERQVRKAQRQYVE
MSMEG_4718|M.smegmatis_MC2_155 PAKALDALVDFHLDFAFDESDLIRIQDRDLAHLPDTAKRQVRRAQRQYVE
Mflv_2551|M.gilvum_PYR-GCK AASTLENLIDFHLDFALDESDLIRIQDRDLGNLPPAAKRQVRRKQRQYVE
Mvan_4092|M.vanbaalenii_PYR-1 ADSALEGLIDFHLDFVFGEPDLIRIQDRDLGNLPPAAKRQVRRKQRQYVE
MAV_5066|M.avium_104 AMDRLLIAAEAHLRHELEVSDYTTASIRNAGQIPPPIRKRQLLEEARYGE
TH_3291|M.thermoresistible__bu ALDRLLTAVATHLQHALEISDYATAAIRNAGQVPLAIRKRQIREEERYGE
MAB_0901c|M.abscessus_ATCC_199 AIDRLENLVKRSIQVLVQELPYVTLLLRIRGNT--AAERRALARRREFDD
* : . * .: .:: . .: :
Mb2534|M.bovis_AF2122/97 VWVGVLRELNPG---LAEADARLMAHAVFGLLNSTPHSMKAADSKP-ART
Rv2506|M.tuberculosis_H37Rv VWVGVLRELNPG---LAEADARLMAHAVFGLLNSTPHSMKAADSKP-ART
MMAR_3853|M.marinum_M IWVGVLRQLDPG---LAEADARLMAHAAFGLLNSTPHSMKSADTKS-ACA
MUL_3785|M.ulcerans_Agy99 IWVGVLRQLDPG---LAEADARLMAHAAFGLLNSTPHSMESADTKS-ACA
MSMEG_4718|M.smegmatis_MC2_155 IWVSVLTRLRRD---LPEEEARVMAHATFGLLNSTPHSVKPAVTKAQSST
Mflv_2551|M.gilvum_PYR-GCK IWVDVLRRCTPG---LSEADARLMAHGTFGLLNSTAHSMKPGTTKT--AE
Mvan_4092|M.vanbaalenii_PYR-1 IWVDVLRRRTPG---LTETDARLMAHAAFGLLNSTPHGVKPGLNKA--AE
MAV_5066|M.avium_104 LWRKLINDVACEGLLWPQLDLHIAQMLVLGALNWAVEWWNPRRGSIESVV
TH_3291|M.thermoresistible__bu VWRRLINDLAREGQLRPELDLYIAQMLILGALNWAAEWWDPRRSSVETVI
MAB_0901c|M.abscessus_ATCC_199 IVGNLVEEACNEGSIRAGVDPALTSRLIFGTVNSLIEWYRPSRTLSADEV
: :: . : : :* :* . .
Mb2534|M.bovis_AF2122/97 VRARAVLRAMTVAALSAADRCL-
Rv2506|M.tuberculosis_H37Rv VRARAVLRAMTVAALSAADRCL-
MMAR_3853|M.marinum_M PHSRAVMRAMTVAALTVDVGA--
MUL_3785|M.ulcerans_Agy99 PHSRAVMRAMTVAALTVDVGA--
MSMEG_4718|M.smegmatis_MC2_155 AQSRGVLRRMTVAALTATG----
Mflv_2551|M.gilvum_PYR-GCK AGSRTVLREMTVAALTSAERRRG
Mvan_4092|M.vanbaalenii_PYR-1 ASSRTVLRTMTVAALTSAGRRA-
MAV_5066|M.avium_104 RNAQLIIRHGLTDGATA------
TH_3291|M.thermoresistible__bu ANAQTIIKHGITTVE--------
MAB_0901c|M.abscessus_ATCC_199 ADAVATMIFDGLRTRSGQH----
: :