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MATVVSPDGTVIGYESVGAGPPLLLVHGSTGTRARWRPVTPELARRYTVHAMDRRGRGLSTAEAEPYSLG REAEDVAAVAEAVGGDVYVVGHSYGALAVLDAAPITRAFRRIVLYEPPIPSLGLDVGSPGGWARITALSD PRDILEAFYRETLQLSESAIKDLANREFPYLAGSIRHTAGRELAQTRAYRLTERHANITTPVRMLLGTES PAYLRAATAVLAAKIPGATIVALHGQGHQAIDYDPDQFARAVLEFDSEEVDSGGVGAVTA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4984 | - | - | 100% (270) | alpha/beta hydrolase fold-1 |
| M. avium 104 | MAV_2275 | - | 4e-10 | 38.24% (102) | short chain dehydrogenase |
| M. avium 104 | MAV_3609 | - | 9e-10 | 24.82% (282) | hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2734 | - | 2e-08 | 23.51% (285) | hydrolase |
| M. gilvum PYR-GCK | Mflv_3856 | - | 1e-11 | 29.20% (250) | alpha/beta hydrolase fold |
| M. tuberculosis H37Rv | Rv2715 | - | 2e-08 | 23.51% (285) | hydrolase |
| M. leprae Br4923 | MLBr_00862 | ephD | 2e-10 | 32.20% (118) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0130 | - | 1e-28 | 34.13% (252) | putative hydrolase |
| M. marinum M | MMAR_2050 | - | 2e-16 | 30.40% (273) | hypothetical protein MMAR_2050 |
| M. smegmatis MC2 155 | MSMEG_2984 | - | 1e-16 | 28.99% (238) | putative hydrolase |
| M. thermoresistible (build 8) | TH_3727 | - | 8e-10 | 37.25% (102) | PUTATIVE Chloride peroxidase |
| M. ulcerans Agy99 | MUL_3299 | - | 5e-12 | 38.14% (118) | hypothetical protein MUL_3299 |
| M. vanbaalenii PYR-1 | Mvan_3576 | - | 3e-13 | 45.10% (102) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2734|M.bovis_AF2122/97 ----------------------------MTERKRNLRPVRDVAPPT---L
Rv2715|M.tuberculosis_H37Rv ----------------------------MTERKRNLRPVRDVAPPT---L
MAV_4984|M.avium_104 --------------------------------------MATVVSP-----
MAB_0130|M.abscessus_ATCC_1997 ----------------------------------MVSIARYVAAP-----
MLBr_00862|M.leprae_Br4923 ---------------------------MPATQSIHKVPHQFVESP-----
Mvan_3576|M.vanbaalenii_PYR-1 -----------------------------------MSTQRFVESS-----
MMAR_2050|M.marinum_M MRPTLAAAALAGASGLVGWGGARALARRIERNPDPFPRERLLAEPQGERV
MUL_3299|M.ulcerans_Agy99 MRPTLAAAALAGASGLVGWGGARALARRIERNPDPFPRERLLAEPQGERV
MSMEG_2984|M.smegmatis_MC2_155 ------------------------------MILTHAEPLHLSLET-----
TH_3727|M.thermoresistible__bu --------------------------------------MATITTS-----
Mflv_3856|M.gilvum_PYR-GCK -----------------------------------------MDVR-----
Mb2734|M.bovis_AF2122/97 QFRTVHGYRRAFRIAG--SGPAILLIHGIGDNSTTWNGVHAKLAQR-FTV
Rv2715|M.tuberculosis_H37Rv QFRTVHGYRRAFRIAG--SGPAILLIHGIGDNSTTWNGVHAKLAQR-FTV
MAV_4984|M.avium_104 -----DGTVIGYESVG--AGPPLLLVHGSTGTRARWRPVTPELARR-YTV
MAB_0130|M.abscessus_ATCC_1997 -----DGVRLSVTVSG--TGPSLVLVHGSLQSGSSWAGVVSELESD-FTC
MLBr_00862|M.leprae_Br4923 -----DGVRLAIYQSGQPEGPAIVLVHGFPDSHVLWDGVVPLLAKR-FRI
Mvan_3576|M.vanbaalenii_PYR-1 -----DGVRIAVSEQGNPDGPTLVLVHGLRDTHRVWDPVVALLADR-FRI
MMAR_2050|M.marinum_M AITRPDGTVLHALVAG--RGTPVILVHGYCASLTEWNFVWDELLARGLRV
MUL_3299|M.ulcerans_Agy99 AITRPDGTVLHALVAG--RGTPVILVHGYCASLTEWNFVWDELLARGLRV
MSMEG_2984|M.smegmatis_MC2_155 -----ADTRLSAEVRPG-HGTPVVIVPGIMADAATWRPVVAHIDLP-NPV
TH_3727|M.thermoresistible__bu -----DGVEIFYRDWG--SGQPIVFSHGWPLTADDWDPQMLFFLNAGYRV
Mflv_3856|M.gilvum_PYR-GCK -------IRNSVRVVGRPDGRPLMLAHGFGCDQNLWRLVVPLLSDR-FRI
* .::: * * :
Mb2734|M.bovis_AF2122/97 IAPDLLGHGQSD----KPRADYSVAAYANGMRDLLSVLDIER-VTIVGHS
Rv2715|M.tuberculosis_H37Rv IAPDLLGHGQSD----KPRADYSVAAYANGMRDLLSVLDIER-VTIVGHS
MAV_4984|M.avium_104 HAMDRRGRGLST----AEAEPYSLGREAEDVAAVAEAVGGD--VYVVGHS
MAB_0130|M.abscessus_ATCC_1997 FAVDRRGHGAS-----SDAEEHSLQREADDVIAVAAEVGPD--AVIVAHS
MLBr_00862|M.leprae_Br4923 VRYDNRGVGQSSV--PKPVSAYTMTRFADDFAAVIDELSPDRPVHVLAHD
Mvan_3576|M.vanbaalenii_PYR-1 VAYDTRGAGNSGA--PKQTSAYTVDRFADDFAAVAAAVGGDTPVHVLAHG
MMAR_2050|M.marinum_M IAFDQRGHGRST----LGAEGIGSEPMADDLAAVLQHFDIRDGVLVGHSM
MUL_3299|M.ulcerans_Agy99 IAFDQRGHGRST----LGAEGIGSEPMADDLAAVLQHFDLRDGVLVGHSM
MSMEG_2984|M.smegmatis_MC2_155 VTLNRRGRASSG----GLGADYSVAVEVDDLRRVVGALGAVH---LVGWS
TH_3727|M.thermoresistible__bu IAHDRRGHGRSS----PVPDGHDMDHYADDLAALVEHLGLRDAVHVGHST
Mflv_3856|M.gilvum_PYR-GCK VLFDHVGSGSSDAGAWTAKRYADLQQYADDILEIVDDMRLREVVYVGHSV
: * . * .:.. : . :
Mb2734|M.bovis_AF2122/97 LGGGVAMQFAYQFPQLVDRLILVSAGGVTKDVNIVFRLASLPMGSEAMAL
Rv2715|M.tuberculosis_H37Rv LGGGVAMQFAYQFPQLVDRLILVSAGGVTKDVNIVFRLASLPMGSEAMAL
MAV_4984|M.avium_104 YGALAVLDAAPIT---RAFRRIVLYEPPIPSLGLDVGSPGGWARITALSD
MAB_0130|M.abscessus_ATCC_1997 YGAVVVLEAVRRG---ADVAAVVLYEPPLP-ISERVASAN----------
MLBr_00862|M.leprae_Br4923 WGSVGVWEYLSRSGASDRVASFTSVSGPSQDQLVDYILSGLRRPWRPRTF
Mvan_3576|M.vanbaalenii_PYR-1 WGAAGVWQYLKRADAPERVASLTSVSGPSPEHVAGYVRAALTS---PRRF
MMAR_2050|M.marinum_M GGFVSIRALLDHGALAQRLRAVVLFATWAGRVLDGAPQNRLQIPLLERGI
MUL_3299|M.ulcerans_Agy99 GGFVSIRALLDHGALAQRLRAVVLFATWAGRVLDGAPQNRLQIPLLERGI
MSMEG_2984|M.smegmatis_MC2_155 YGALIGLEAALGSGRIRSVTAYEPVSRPFAPETVAPIRAAVAAGDLDRAV
TH_3727|M.thermoresistible__bu GGGVVVRYLARHGEERTAKAVLIAAVPPLMVRTDANPGGLPKSVFDDFQA
Mflv_3856|M.gilvum_PYR-GCK AAMMGVLAAAKNPGAFAGLVLLTPSPRYLDDADYRGGFTRSEIDELLDSI
.
Mb2734|M.bovis_AF2122/97 LRLPLVLPAVQIAG------------------------------------
Rv2715|M.tuberculosis_H37Rv LRLPLVLPAVQIAG------------------------------------
MAV_4984|M.avium_104 PRDILEAFYR----------------------------------------
MAB_0130|M.abscessus_ATCC_1997 -RDASAALR-----------------------------------------
MLBr_00862|M.leprae_Br4923 ARAVSQLFRLTYMVLFSIPVLVPMVLWIALSSATIRRTMVDNISTDQIHH
Mvan_3576|M.vanbaalenii_PYR-1 VRGAGQLVR--------------------LAAAAPR--------------
MMAR_2050|M.marinum_M LQRLLRSRTIAVLFG-----------------------------------
MUL_3299|M.ulcerans_Agy99 LQRLLRSRTIAVLFG-----------------------------------
MSMEG_2984|M.smegmatis_MC2_155 ALVNTDVSG-----------------------------------------
TH_3727|M.thermoresistible__bu QLAANRSEFYRALASG----------------------------------
Mflv_3856|M.gilvum_PYR-GCK ESNYLGWSR-----------------------------------------
Mb2734|M.bovis_AF2122/97 ---------------------RIVGKAIGTTSLGHDLPNVLRILDDLPEP
Rv2715|M.tuberculosis_H37Rv ---------------------RIVGKAIGTTSLGHDLPNVLRILDDLPEP
MAV_4984|M.avium_104 -----------------------------ETLQLSESAIKDLANREFPYL
MAB_0130|M.abscessus_ATCC_1997 -------------------------------------GRSTVVTREW---
MLBr_00862|M.leprae_Br4923 SATLARDAAHSVKTYPANYFRAFSGRRRGKGVPVVNVPVQLIVNTMDRYV
Mvan_3576|M.vanbaalenii_PYR-1 --------AATAKPYRANLRPAAP-----AGVP-VDVPVQLIVPDHDPHV
MMAR_2050|M.marinum_M --------------------------AAQCGARPSPAMISVFLEWFHQHL
MUL_3299|M.ulcerans_Agy99 --------------------------AAQCGARPSPAMISG-IPRVVPST
MSMEG_2984|M.smegmatis_MC2_155 ---------------------------------FSDDYVAGLRRSPAWEV
TH_3727|M.thermoresistible__bu --------------------------PFYGFNRDGVEPSEALIANWWRQG
Mflv_3856|M.gilvum_PYR-GCK ---------------------------AMAPVIMGTPERPDLEGELADTF
Mb2734|M.bovis_AF2122/97 TASAAFGRTLRAVVDWRGQMVTMLDR-------CYLTEAIPVQIIWGTKD
Rv2715|M.tuberculosis_H37Rv TASAAFGRTLRAVVDWRGQMVTMLDR-------CYLTEAIPVQIIWGTKD
MAV_4984|M.avium_104 AGSIRHTAGRELAQTRAYRLTERHAN-----------ITTPVRMLLGTES
MAB_0130|M.abscessus_ATCC_1997 -----------MAVNRSVESIGEYTR-----------AATPMYLLEGANS
MLBr_00862|M.leprae_Br4923 RPYGYDATARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDLADLVDGKQP
Mvan_3576|M.vanbaalenii_PYR-1 GPHVYDGMSASVSRLWRRDIKTGDLSPGSHPQVLARAVDQLVDHLGGAPA
MMAR_2050|M.marinum_M DRHGPHLPIVRA--FSREDRYPRLAE---------ISVP--AVVMVGSSD
MUL_3299|M.ulcerans_Agy99 SRPARTAPTHRAGVLARGSLSTAGRD---------LGAGGGDGGLLGSHH
MSMEG_2984|M.smegmatis_MC2_155 LRPLAQPMGEELAAIDAFEPSFDDYR----------HLTVPVTLILGALN
TH_3727|M.thermoresistible__bu MMGDAKAHYDGIVAFSQTDFTEDLTK-----------ITVPVLVMHGDDD
Mflv_3856|M.gilvum_PYR-GCK CRTDPQRALAFARATFLSDNRTDLAR-----------VTVPTVVIECARD
:
Mb2734|M.bovis_AF2122/97 VVLPVRHAHMA--HAAMPGSQLEIFEGSGHFPFHDDPARFIDIVERFMDT
Rv2715|M.tuberculosis_H37Rv VVLPVRHAHMA--HAAMPGSQLEIFEGSGHFPFHDDPARFIDIVERFMDT
MAV_4984|M.avium_104 PAYLRAATAVL--AAKIPGATIVALHGQGHQAIDYDPDQFARAVLEFD-S
MAB_0130|M.abscessus_ATCC_1997 PPQFRDPVGYL--ARRVPGVRVKELVGQDHFAHREAPAVFAQALRELL-L
MLBr_00862|M.leprae_Br4923 SRALLRAQVGR--SRDTFGDTLVSVTGAGSGIGRETALALARRGAEVV-V
Mvan_3576|M.vanbaalenii_PYR-1 PRELLRAQVGR--ARKVFGDTLVSVTGAASGIGRETALAFARAGADVV-I
MMAR_2050|M.marinum_M RTTPPSHSHRL--AAGIPG---ARLVT--VPGAGHLLN--WEAVDELAEV
MUL_3299|M.ulcerans_Agy99 PAQPLAPAGRR--NPGCPAGHRARRGTPAELGGGRRAGRSRRILCGAAVL
MSMEG_2984|M.smegmatis_MC2_155 EGAAPYGTAFVPFSAALPQARLARLPGQGHLAHVEAPADLADAISRAVRH
TH_3727|M.thermoresistible__bu QVVPYANSGPLT-AELLRNAKLKTYQGFPHGMMTTHAEVVNADILEFLRS
Mflv_3856|M.gilvum_PYR-GCK TLAPREVGAYC--HEQIAGSTLVTLDASGHCPHLSAPEDTAAAIADFALR
Mb2734|M.bovis_AF2122/97 TEPAEYDQAALRALLRRGGGEATVTGSADTRVAVLNAIGSNERSAT----
Rv2715|M.tuberculosis_H37Rv TEPAEYDQAALRALLRRGGGEATVTGSADTRVAVLNAIGSNERSAT----
MAV_4984|M.avium_104 EEVDSGGVGAVTA-------------------------------------
MAB_0130|M.abscessus_ATCC_1997 S-------------------------------------------------
MLBr_00862|M.leprae_Br4923 SDIDEAAAKNTAAQIVASGGVAYAYALDVSDAAAVEAFAEQVSAKHGVPD
Mvan_3576|M.vanbaalenii_PYR-1 SDVDEAGLEQTARLVTAAGAAAHSYTVDVADAAAVEAMAELVCAAHGVPD
MMAR_2050|M.marinum_M VESFAAQR------------------------------------------
MUL_3299|M.ulcerans_Agy99 MRGHAAGVWR----------------------------------------
MSMEG_2984|M.smegmatis_MC2_155 AEGT----------------------------------------------
TH_3727|M.thermoresistible__bu --------------------------------------------------
Mflv_3856|M.gilvum_PYR-GCK L-------------------------------------------------
Mb2734|M.bovis_AF2122/97 --------------------------------------------------
Rv2715|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4984|M.avium_104 --------------------------------------------------
MAB_0130|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 IVVNNAGIGQAGRFLDTPPEEFDRVLAVNLGGVVNCCRAFGQRLVERGTG
Mvan_3576|M.vanbaalenii_PYR-1 IVVNNAGVGHAGFFLDTPAEEFDRVLGINFGGVVNGCRSWGRRLVDRGTG
MMAR_2050|M.marinum_M --------------------------------------------------
MUL_3299|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2984|M.smegmatis_MC2_155 --------------------------------------------------
TH_3727|M.thermoresistible__bu --------------------------------------------------
Mflv_3856|M.gilvum_PYR-GCK --------------------------------------------------
Mb2734|M.bovis_AF2122/97 --------------------------------------------------
Rv2715|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4984|M.avium_104 --------------------------------------------------
MAB_0130|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 GHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDAVGVGLTTIC
Mvan_3576|M.vanbaalenii_PYR-1 GHIVNVASMASYTPVNVMNAYCTSKAAVFMFSDCLRAELDSAGIGVTTIC
MMAR_2050|M.marinum_M --------------------------------------------------
MUL_3299|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2984|M.smegmatis_MC2_155 --------------------------------------------------
TH_3727|M.thermoresistible__bu --------------------------------------------------
Mflv_3856|M.gilvum_PYR-GCK --------------------------------------------------
Mb2734|M.bovis_AF2122/97 --------------------------------------------------
Rv2715|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4984|M.avium_104 --------------------------------------------------
MAB_0130|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_00862|M.leprae_Br4923 PGVIDTNIIQSTRIDTPTAKQERVRDRRGQLDMMFRLRRYGPDKVADTIL
Mvan_3576|M.vanbaalenii_PYR-1 PGVIGTNIVDTTRFSLPEARRDDAESIRRRARQGFAVRRVGPDKVAKAIV
MMAR_2050|M.marinum_M --------------------------------------------------
MUL_3299|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_2984|M.smegmatis_MC2_155 --------------------------------------------------
TH_3727|M.thermoresistible__bu --------------------------------------------------
Mflv_3856|M.gilvum_PYR-GCK --------------------------------------------------
Mb2734|M.bovis_AF2122/97 ----------------------------------------
Rv2715|M.tuberculosis_H37Rv ----------------------------------------
MAV_4984|M.avium_104 ----------------------------------------
MAB_0130|M.abscessus_ATCC_1997 ----------------------------------------
MLBr_00862|M.leprae_Br4923 SAIKKNKPIRPVAPEAYALYGISRVLPQVLRSTARIRVI-
Mvan_3576|M.vanbaalenii_PYR-1 AAVQKNKPVRPVTTEAYLVYGVAHALPQAMRSAARGGNIM
MMAR_2050|M.marinum_M ----------------------------------------
MUL_3299|M.ulcerans_Agy99 ----------------------------------------
MSMEG_2984|M.smegmatis_MC2_155 ----------------------------------------
TH_3727|M.thermoresistible__bu ----------------------------------------
Mflv_3856|M.gilvum_PYR-GCK ----------------------------------------