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VPAEASRFLWYIPNTVEPGHRGDDTVDGWGSLDYSVDLASRAEQHGWEGALIGTGWGRPDTFTVATAIAA RTTAFAPLVAVRPGYWHPAHFASAAATLDRLNGGRLLVNIVSGADDVAAYGDTEVDKSRRYDRTREFIRL LRRLWTQDDVTFHGEFFRVEHSTLRPRPLGAEQGRHPKLYFGGASPAAEQVAATDADVQLFWGESLDGIA ERIDRLKSLSDKLGREHPPLEFGLRVTTLVRDTSEQAWRDAEAKVAKLAGTPTMMLLHDPAGSEGQRRLN DLAARGEVIDSCLYTTPSKYGGEGAGTTWLVGSAAEVAAALRAYADLGVSHFVLSDTPYQSEVVRLGDQL LPLLRHTALAN
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3426 | - | - | 100% (361) | alkanesulfonate monooxygenase |
| M. avium 104 | MAV_4628 | - | 3e-50 | 36.59% (369) | alkanesulfonate monoxygenase family protein |
| M. avium 104 | MAV_4445 | - | 3e-14 | 29.88% (251) | hypothetical protein MAV_4445 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0815c | - | 2e-11 | 29.63% (162) | hypothetical protein Mb0815c |
| M. gilvum PYR-GCK | Mflv_5136 | - | 2e-49 | 36.77% (378) | alkanesulfonate monooxygenase |
| M. tuberculosis H37Rv | Rv0791c | - | 2e-11 | 29.63% (162) | hypothetical protein Rv0791c |
| M. leprae Br4923 | MLBr_00269 | - | 2e-07 | 27.70% (148) | putative F420-dependent glucose-6-phosphate dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2219 | - | 2e-48 | 36.05% (380) | putative alkanesulfonate monooxygenase |
| M. marinum M | MMAR_4200 | fgd2 | 2e-48 | 35.95% (370) | F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. smegmatis MC2 155 | MSMEG_4103 | - | 1e-132 | 63.79% (359) | alkanesulfonate monooxygenase |
| M. thermoresistible (build 8) | TH_3352 | - | 1e-49 | 36.68% (368) | PUTATIVE Alkanesulfonate monooxygenase |
| M. ulcerans Agy99 | MUL_4507 | fgd2 | 2e-49 | 36.51% (367) | F420-dependent glucose-6-phosphate dehydrogenase Fgd2 |
| M. vanbaalenii PYR-1 | Mvan_1200 | - | 2e-49 | 37.17% (382) | alkanesulfonate monooxygenase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_3426|M.avium_104 -------------------------MPAEASRFLWYIPN------TVEPG
MSMEG_4103|M.smegmatis_MC2_155 ----------------------------MTSEFLWYIPN------QVEPG
MMAR_4200|M.marinum_M ----------------------------MALSFHWFLPTYGDSRGLVAGG
MUL_4507|M.ulcerans_Agy99 ----------------------------MALLFHWFLPTYGDSRGLVAGG
Mflv_5136|M.gilvum_PYR-GCK --------------------------MTHAIKLHWFLPTYGDSRHIVGGG
Mvan_1200|M.vanbaalenii_PYR-1 MCTVAVLQIPLTQTADLPTPSGHHLVVTSAIKLHWFLPTYGDSRLIVGGG
TH_3352|M.thermoresistible__bu ----------------------------VTIKLHWFLPTYGDSRLIVGGG
MAB_2219|M.abscessus_ATCC_1997 ----------------------------MAAKFFWFLPTNGDSRSIVGAS
Mb0815c|M.bovis_AF2122/97 ---------------MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTA
Rv0791c|M.tuberculosis_H37Rv ---------------MNAKDDPHFGLMLAATVNGLAVGSYREMVVVSQTA
MLBr_00269|M.leprae_Br4923 ----------------------------MAELRLGYKASAEQ----FAPR
: .
MAV_3426|M.avium_104 HR---------------GDDTVDGWGSLDYSVDLASRAEQHGWEGALIGT
MSMEG_4103|M.smegmatis_MC2_155 HR---------------GDPTVDGHNSLETLVSHATALEQHGWAGALIGT
MMAR_4200|M.marinum_M HG------------LPMS---GNRPATLRYLNQIAAAAESNGFEAVLTPA
MUL_4507|M.ulcerans_Agy99 HG------------LPMS---GNRPATLRYLNQIAAAAESNGFEAVLTPA
Mflv_5136|M.gilvum_PYR-GCK HG------------TPAGSAHSDRDASIDYLASIVRAAETFGFTGALIPT
Mvan_1200|M.vanbaalenii_PYR-1 HG------------TPAGAARGDRDASIDYLASIVRAAETFGFTGALIPT
TH_3352|M.thermoresistible__bu HG------------TPAGAAGGDRDASIDYLASIVRAAETFGFTGALIPT
MAB_2219|M.abscessus_ATCC_1997 HAS-----------THHTVPEGYREPSLRYLGEVARAADRLGFEGVLTPT
Mb0815c|M.bovis_AF2122/97 EEYGFDSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSR
Rv0791c|M.tuberculosis_H37Rv EEYGFDSVWLCDHFLTISPGEYAKVAGIAADTGSATGTETGGAGQCAPSR
MLBr_00269|M.leprae_Br4923 --------------------ELVELGVAAEAHGMDSATVSDHFQPWRHQG
MAV_3426|M.avium_104 GWGRPDTFTVATAIAARTTAFAPLVAVRP-GYWHPAHFASAAATLDRLNG
MSMEG_4103|M.smegmatis_MC2_155 GWGRPDTFTVATALAARTSTFEPLIAIRP-GYWRPANFAAATATLDHLTA
MMAR_4200|M.marinum_M GLWCEDAWLTTAMLVGTTETLKFLVALRP-GLVSPTLAAQMATTFQQQSG
MUL_4507|M.ulcerans_Agy99 GLWCEDAWLTTAMLVGTTKTLKFLVALRP-GLVSPTLAAQMATTFQQQSG
Mflv_5136|M.gilvum_PYR-GCK GAWCEDAFITAALLARETSTLGFLVAFRP-GLVSPTLSAQMAATFARHAP
Mvan_1200|M.vanbaalenii_PYR-1 GAWCEDAFITAALLARETTSLAFLVAFRP-GLVSPTLSAQMAATFARHAP
TH_3352|M.thermoresistible__bu GAWCEDAFITAALLARETTSLGFLVAFRP-GLVSPTLSAQMAATFARHAP
MAB_2219|M.abscessus_ATCC_1997 GTWCEDAWLTAAGLLDQTERLKFLVAFRP-GLVPPTLAAQQAATLQRFSN
Mb0815c|M.bovis_AF2122/97 SLPLLECWTALAALSRDTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQ
Rv0791c|M.tuberculosis_H37Rv SLPLLECWTALAALSRDTTKLRLGTSVLCNSYRHPSVLAKMAATLDVISQ
MLBr_00269|M.leprae_Br4923 GHASFSLSWMTAVGERTNRILLGTSVLTPTFRYNPAVIGQAFATMGCLYP
. . : . : . *: . :*:
MAV_3426|M.avium_104 GRLLVNIVSGAD--DVAA-YGDTEVDKSRRYDRTREFIRLLRRLWT-QDD
MSMEG_4103|M.smegmatis_MC2_155 GRVRVNIVSGKD--DLGA-YGDSDAEQTDRYARTREFLQVVRRLWT-EEN
MMAR_4200|M.marinum_M GRLLLNVVTGGEAHEQRA-YGD-FLDKQQRYRRTGEFLHVVRQLWASGQP
MUL_4507|M.ulcerans_Agy99 GRLLVNVVTGGEAHEQRA-YGD-FLDKQQRYRRTGEFLHVVRQLWASGQP
Mflv_5136|M.gilvum_PYR-GCK GRLLLNVVVGGEAHEQRS-FGD-HLDKDGRYARADEFLDVVRRLWD-GQT
Mvan_1200|M.vanbaalenii_PYR-1 GRILLNVVVGGEAHEQRS-FGD-YLDKEGRYARADEFLDVVRRLWD-GQT
TH_3352|M.thermoresistible__bu GRILLNVVVGGESHEQRA-FGD-HLDKDERYRRADEFLEVVRRLWA-GET
MAB_2219|M.abscessus_ATCC_1997 GRLLLNVVSGGDDAEQRR-FGD-WLTHDERYERTGEFLQIVRDIWR-GSP
Mb0815c|M.bovis_AF2122/97 GRLDLGLGAGWFRRESQA-YGIPFPPVGDRVSALAESLQVIKAVWT-EPN
Rv0791c|M.tuberculosis_H37Rv GRLDLGLGAGWFRRESQA-YGIPFPPVGDRVSALAESLQVIKAVWT-EPN
MLBr_00269|M.leprae_Br4923 NRVFLGVGTGEALNEVATGYQGAWPEFKERFARLRESVRLMRELWR-GDR
.*: :.: * : : * * : ::: :*
MAV_3426|M.avium_104 VTFHGEFFRVEHSTLRPRPLGAEQGRHPKLYFGGASPAAEQVAATDADVQ
MSMEG_4103|M.smegmatis_MC2_155 VTYRGEYFQVENSTVQPRINIRGNRSHPKLYFGGASEAAERVAAAEADVQ
MMAR_4200|M.marinum_M VTFEGEHIHVHQAQLGRLPDPP-----PPVFFGGSSESAGAVAARYADTY
MUL_4507|M.ulcerans_Agy99 VTFEGEHIHVHQAQLGRLPDPP-----PPVFFGGSSESAGAVAARYADTY
Mflv_5136|M.gilvum_PYR-GCK VSLDGEHIRVENASLPTVPAPV-----PPLYFGGSSAAAGPVAARHADVY
Mvan_1200|M.vanbaalenii_PYR-1 VTLDGEHIRVEGASLATLPDPA-----PPLYFGGSSAAAGPVAARHADVY
TH_3352|M.thermoresistible__bu VTLHGRHIRVEDAALPTLPDPV-----PPLYFGGSSTAAGPVAARHADVY
MAB_2219|M.abscessus_ATCC_1997 VDFSGKHYTVTDARVSEPPSPL-----PELYFGGSSPAALPIAADHVDVY
Mb0815c|M.bovis_AF2122/97 PTYAGRFYTLDGATCDPPPVQR---PHPPLWIGGEGDRVQRIAAKHAQGL
Rv0791c|M.tuberculosis_H37Rv PTYAGRFYTLDGATCDPPPVQR---PHPPLWIGGEGDRVQRIAAKHAQGL
MLBr_00269|M.leprae_Br4923 VDFDGDYYQLKGASIYDVPEGG-----VPIYIAAGGPEVAKYAGRAGEGF
* . : : :::.. . . *. :
MAV_3426|M.avium_104 LFWGESLDGIAER--IDRLKSLSDKLGREHPPLEFGLRVTTLVRDTSEQA
MSMEG_4103|M.smegmatis_MC2_155 LFWGEPLADVAER--IERLRALSEEMGREHAPLEFGLRVTTFVRDTTDQA
MMAR_4200|M.marinum_M LTWGEPLSAVGKK--IDWIRGLAADHGRA---LSYGLRIHVITRDTAEEA
MUL_4507|M.ulcerans_Agy99 LTWGEPLSAVGKK--IDWIRGLAADHGRA---LSYGLRIHVITRDTAEEA
Mflv_5136|M.gilvum_PYR-GCK LTWGEPPAAVAEK--VEWIRRAAAGQGRQ---LRFGIRLHVITRDTAGAA
Mvan_1200|M.vanbaalenii_PYR-1 LTWGEPPAAVADK--VDWIRRLAAKQGRQ---VRFGIRLHVITRDAADEA
TH_3352|M.thermoresistible__bu LTWGEPPDAVREK--IDWIRTLAAAEGRR---VRFGIRLHTISRDTADEA
MAB_2219|M.abscessus_ATCC_1997 LTWGEPPAAAAAK--IEAVRALAKERGRT---LRFGIRLHTISRDTSEAA
Mb0815c|M.bovis_AF2122/97 NVRWWSPQQVTQR--RGFLTQASEAAGRDPDTLRLSVTLLLAPTQSGEEE
Rv0791c|M.tuberculosis_H37Rv NVRWWSPQQVTQR--RGFLTQASEAAGRDPDTLRLSVTLLLAPTQSGEEE
MLBr_00269|M.leprae_Br4923 VCTSGKGEELYTEKLIPAVLEGAAVAGRDADDIDKMIEIKMSYDPDPEQA
. : : ** : : :
MAV_3426|M.avium_104 WRDAEAKVAKLAGTP---------TMMLLHDPAGSEGQRRLNDLAARG--
MSMEG_4103|M.smegmatis_MC2_155 WADAEMKVAQMATAQRGGRSDEHGTLPQNTHRRTAVGQQRLFNLAARG--
MMAR_4200|M.marinum_M WRVADRLLAGIDPAD-------IERMQANLARSESEGQRRMAELHGG---
MUL_4507|M.ulcerans_Agy99 WRVADRLLAGIDPAD-------IERMQANLARSESEGQRRMAELHGG---
Mflv_5136|M.gilvum_PYR-GCK WAEADRLVGALDDET-------VRNAQEGLGRSQSEGQRRMSALHQAHRA
Mvan_1200|M.vanbaalenii_PYR-1 WSQADKLVSALDDET-------VRSAQAGLGRSQSEGQRRMLALHEAHRA
TH_3352|M.thermoresistible__bu WAQADKLIGALDEHT-------VRAAQAGLRRSESEGQRRMLALHQANRA
MAB_2219|M.abscessus_ATCC_1997 WAVANSLVGELTPDQ-------IAKATALHSKSESEGQRRMTALHGG---
Mb0815c|M.bovis_AF2122/97 VRIREEFASIPEPGL-----------------------------------
Rv0791c|M.tuberculosis_H37Rv VRIREEFASIPEPGL-----------------------------------
MLBr_00269|M.leprae_Br4923 LSNIRFWAPLSLAAEQ------KHSIDDPIEMEKVADALPIEQVAKR---
MAV_3426|M.avium_104 ---EVIDSCLYTTPSKYGGE----GAGTTWLVGSAAEVAAALRAYADLGV
MSMEG_4103|M.smegmatis_MC2_155 ---EVLDDNLYTTPGQFGGG----GAGTTWLVGSAEDVAKSLRKYQDLGI
MMAR_4200|M.marinum_M -----ALDQLEIAPNLWAGVGLVRGGAGTALVGSHQEVAERIIEYARLGI
MUL_4507|M.ulcerans_Agy99 -----VLDQLEIAPNLWAGVGLVRGGAGTALVGSHQEVAERIIEYARLGI
Mflv_5136|M.gilvum_PYR-GCK NGSWHDARTLEVAPNLWTGVGLVRGGAGTALVGSHSEVADRIAEYAEVGI
Mvan_1200|M.vanbaalenii_PYR-1 DGSWHDARSLEIAPNLWAGVGLVRGGAGTALVGSHTEVADRIAEYAEAGI
TH_3352|M.thermoresistible__bu DGSWRSARSLEVAPNLWAGVGLVRGGAGTALVGSHAEVADRIAEYAAAGI
MAB_2219|M.abscessus_ATCC_1997 -----RLDKLEIYPNLWAGVGLVRGGAGTALVGSHEEVANLISEYHALGF
Mb0815c|M.bovis_AF2122/97 ------------------------------IVGTPDRCVERIREYQDRGV
Rv0791c|M.tuberculosis_H37Rv ------------------------------IVGTPDRCVERIREYQDRGV
MLBr_00269|M.leprae_Br4923 ----------------------------WIVVSDPDEAVARVGQYVTWGL
:*. . : * *.
MAV_3426|M.avium_104 SHFVLSDTPYQSEVVRL---GDQLLPLLRHTALAN---------------
MSMEG_4103|M.smegmatis_MC2_155 THFVLSDTPYLREIERQ---GDQLLPLLRR--------------------
MMAR_4200|M.marinum_M SHFILSGYPHLEEAYWF---GEGVLPILERKRLWHRPHGSSPHSAALPVA
MUL_4507|M.ulcerans_Agy99 SHFILSGYPHLEEAYWF---GEGVLPILERKRLWHRPHGSSPHSAALPVA
Mflv_5136|M.gilvum_PYR-GCK DEFIFSGYPHLEELYWL---GEGVVPLLRERGLFE-AGPKQAASASIPFV
Mvan_1200|M.vanbaalenii_PYR-1 DEFVFSGYPHLEELFWF---GEGVVPILRDRGLFT-ADVKGAAASSIPFV
TH_3352|M.thermoresistible__bu EEFIFSGYPHLEELFWF---GEGVVPILRSRNLFDGAGDRSPVPAAIPFV
MAB_2219|M.abscessus_ATCC_1997 DEFILSGYPHLEEAYWF---AEGVLPLLKKR---------GALAA-----
Mb0815c|M.bovis_AF2122/97 GHFLFT-IPHVVKSDYLHIIGSDIIPRVKTEVTIP---------------
Rv0791c|M.tuberculosis_H37Rv GHFLFT-IPHVVKSDYLHIIGSDIIPRVKTEVTIP---------------
MLBr_00269|M.leprae_Br4923 NHLVFH-APGHNQRRFLELFEKDLAPRLRRLG------------------
.::: * : . : * :.
MAV_3426|M.avium_104 --------
MSMEG_4103|M.smegmatis_MC2_155 --------
MMAR_4200|M.marinum_M HSSVN---
MUL_4507|M.ulcerans_Agy99 HSSVN---
Mflv_5136|M.gilvum_PYR-GCK GGTGRGRI
Mvan_1200|M.vanbaalenii_PYR-1 GAAR----
TH_3352|M.thermoresistible__bu GAAR----
MAB_2219|M.abscessus_ATCC_1997 --------
Mb0815c|M.bovis_AF2122/97 --------
Rv0791c|M.tuberculosis_H37Rv --------
MLBr_00269|M.leprae_Br4923 --------