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EAWDAICARRNVREYQPRAIAGEDLDRIVEAGWRAPSAKNRQPWDFVIVTDRTQLQELSTVWRGAGHIAG APAAIAIVVPEPPDERRLVTDNYDVGQATMAMMIAATDLGIGAGHSSVGDQDKARAILGVPDGHLVAFLL GVGYPADRPLTPIRKPNRRPFTEVVHRGRW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4540 | - | - | 100% (171) | nitroreductase family protein |
| M. avium 104 | MAV_2661 | - | 2e-11 | 28.50% (193) | nitroreductase |
| M. avium 104 | MAV_1962 | - | 3e-10 | 24.74% (194) | NADPH nitroreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0314 | - | 5e-07 | 26.53% (196) | putative oxidoreductase |
| M. gilvum PYR-GCK | Mflv_1262 | - | 7e-09 | 23.15% (203) | nitroreductase |
| M. tuberculosis H37Rv | Rv0306 | - | 5e-07 | 26.53% (196) | putative oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3351c | - | 3e-08 | 27.81% (151) | putative nitroreductase |
| M. marinum M | MMAR_0959 | - | 1e-81 | 82.46% (171) | nitroreductase |
| M. smegmatis MC2 155 | MSMEG_6258 | - | 7e-08 | 27.87% (183) | nitroreductase family protein |
| M. thermoresistible (build 8) | TH_3507 | - | 8e-05 | 23.12% (186) | PUTATIVE putative nitroreductase |
| M. ulcerans Agy99 | MUL_0710 | - | 3e-57 | 80.16% (126) | nitroreductase |
| M. vanbaalenii PYR-1 | Mvan_5999 | - | 4e-09 | 37.86% (103) | nitroreductase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0959|M.marinum_M -------------MQAWDAICARRNVRQYLP-EPVSEDDLNRIAEAGWRA
MUL_0710|M.ulcerans_Agy99 ----------MGCMQAWDAICARRNVRQYLP-EPVSEDDLNRIAEAGWRA
MAV_4540|M.avium_104 -------------MEAWDAICARRNVREYQP-RAIAGEDLDRIVEAGWRA
Mb0314|M.bovis_AF2122/97 ------MFSAPERRAVYRVIAERRDMRRFVPGGVVSEDVLARLLHAAHAA
Rv0306|M.tuberculosis_H37Rv ------MFSAPERRAVYRVIAERRDMRRFVPGGVVSEDVLARLLHAAHAA
MAB_3351c|M.abscessus_ATCC_199 -------------MDVYQAIATRRDVRAEFTGQVVDDATLMKLLQAAHRA
Mflv_1262|M.gilvum_PYR-GCK ------MDMPHPTDNVWEVLSTARSIRRFTD-EPVDSATLDRCLQAATWA
Mvan_5999|M.vanbaalenii_PYR-1 -------MTSSTGHHVIDLMLARRSVREGFASTAIPVTQLEAIVACGLAA
MSMEG_6258|M.smegmatis_MC2_155 MTDAPSDRLANTSVPIHPPLAARWSPRAFDAAAIVTSEQLTAVLEAARWA
TH_3507|M.thermoresistible__bu -------------VELVEAMRTTGTCRYFRP-DPVPDEVLYQAFDHARFA
: * : * . *
MMAR_0959|M.marinum_M PSAKNRQPWDFVIVTERS-----------ALQELSTVWMGAG--------
MUL_0710|M.ulcerans_Agy99 PSAKNRQPWDFVLVTERS-----------ALQELSTVWMGAG--------
MAV_4540|M.avium_104 PSAKNRQPWDFVIVTDRT-----------QLQELSTVWRGAG--------
Mb0314|M.bovis_AF2122/97 PSVGLMQPWRFIRITDET-----------LKRRIHALVDDERLLTAEALG
Rv0306|M.tuberculosis_H37Rv PSVGLMQPWRFIRITDET-----------LKRRIHALVDDERLLTAEALG
MAB_3351c|M.abscessus_ATCC_199 PSVGNSQPWDFVVIREPG-----------MLDDFAAHVALQRQRFADSLP
Mflv_1262|M.gilvum_PYR-GCK PNGANAQLWRFIVLDGPEQRAAVAQAAQIALQSIESIYGMTRPAPEDDSR
Mvan_5999|M.vanbaalenii_PYR-1 PSSKNAQPWRLHVVQSRT-----------ELVDLAAAVRGAGDAETYVPY
MSMEG_6258|M.smegmatis_MC2_155 ATWGQRQPVRFIVGRRGGQTG--------ADAADETFTTLAG--------
TH_3507|M.thermoresistible__bu PQGGNRQPVRWIVVRDPARKAALQDLYLPLWKNYLSGIADGTVNVGALPK
. * :
MMAR_0959|M.marinum_M ----------HIAAAAAAIALV-----IPVPPDERR----------KVID
MUL_0710|M.ulcerans_Agy99 ----------HIAAAAAAIALV-----IPVPPDERR----------KVID
MAV_4540|M.avium_104 ----------HIAGAPAAIAIV-----VPEPPDERR----------LVTD
Mb0314|M.bovis_AF2122/97 -AREEEFLALKVEGILDCAELL-----VVALCDRRG-SYIFGRRTLPQMD
Rv0306|M.tuberculosis_H37Rv -AREEEFLALKVEGILDCAELL-----VVALCDRRG-SYIFGRRTLPQMD
MAB_3351c|M.abscessus_ATCC_199 EGRRNTFDPIKIEGIRESGTGV-----VVTYDHGRGGPHILGRHTISDAG
Mflv_1262|M.gilvum_PYR-GCK SARNNRATYELHDRAGEFTSVL-----FVAYKNEFS---------SEFLQ
Mvan_5999|M.vanbaalenii_PYR-1 DPSTGEPHPQYRSSVAESADVLGGAS-AAIFIENRG----------VFSG
MSMEG_6258|M.smegmatis_MC2_155 -------LLKRGNSYAHAASALILVC-ADEGEDERT----------ARYA
TH_3507|M.thermoresistible__bu TVRDADYFAEHLAEAPAIVVACAELDGLHPTDTDLG--------RLSIVG
MMAR_0959|M.marinum_M QYDVGQATMAMMIAATDLGIG---TGHSSVGDQDKARA-ILGVPDDHLVA
MUL_0710|M.ulcerans_Agy99 QYDVGQATMAMMIAATDLGIG---TGHSSVGDQDKAR-------------
MAV_4540|M.avium_104 NYDVGQATMAMMIAATDLGIG---AGHSSVGDQDKARA-ILGVPDGHLVA
Mb0314|M.bovis_AF2122/97 LASVSCAIQNLWLAARSEGLG---MGWVSLFDPQRLAA-LLAMPADAEPV
Rv0306|M.tuberculosis_H37Rv LASVSCAIQNLWLAARSEGLG---MGWVSLFDPQRLAA-LLAMPADAEPV
MAB_3351c|M.abscessus_ATCC_199 LFSAVLAIQNLWLAAVTEGIG---VGWVSFYEEQFLAE-LIDAPAHIRPI
Mflv_1262|M.gilvum_PYR-GCK GGSIYPALQNFYLAARAQGLGACITSWASYGGEQALRE-AVGIPDEWFLA
Mvan_5999|M.vanbaalenii_PYR-1 GRRAVVNATREALTGSITGYGFELIGLGAAIENMWLAANALGIGATFMGD
MSMEG_6258|M.smegmatis_MC2_155 AVDAGAAIAQLTIEAVSRGLI---AHPMAGFDVDGARA-AFGVPDGVRPF
TH_3507|M.thermoresistible__bu GASVYPTVQNFCLALRNLGVG--SALTTLLCQVEPEVRELLAIPEGVATA
: *
MMAR_0959|M.marinum_M YLLGVGYPADRPLVP-------IRKPNRRAFAEVVHYGRW----------
MUL_0710|M.ulcerans_Agy99 ----------DPRCP-------RRPPGR--LPAWRRISR-----------
MAV_4540|M.avium_104 FLLGVGYPADRPLTP-------IRKPNRRPFTEVVHRGRW----------
Mb0314|M.bovis_AF2122/97 AILCLGPVPEFPDRPALEL---DGWAYARPLAEFVSENRWSYPSALATDH
Rv0306|M.tuberculosis_H37Rv AILCLGPVPEFPDRPALEL---DGWAYARPLAEFVSENRWSYPSALATDH
MAB_3351c|M.abscessus_ATCC_199 AWLCVGPVREFAERPDLER---FGWRTGRPLEDAVHWGRYRA--------
Mflv_1262|M.gilvum_PYR-GCK GHVVVG----WPRGK-------HGPVRRRPLSDVVFRNHWDPERADITYG
Mvan_5999|M.vanbaalenii_PYR-1 VVIAEEAIKRVVSVTGDVV---GVLALGHIRPDATLHPRPAHEPDLAVWY
MSMEG_6258|M.smegmatis_MC2_155 AVVALGHLGDYATADEAIAERDSRPRERLALEQVAFTGRWGNPL------
TH_3507|M.thermoresistible__bu AHIAIG----YPRDP------FPAKLTRLPVEDVVAAETYDQPFFAPTTV
MMAR_0959|M.marinum_M --------
MUL_0710|M.ulcerans_Agy99 --------
MAV_4540|M.avium_104 --------
Mb0314|M.bovis_AF2122/97 HHGE----
Rv0306|M.tuberculosis_H37Rv HHGE----
MAB_3351c|M.abscessus_ATCC_199 --------
Mflv_1262|M.gilvum_PYR-GCK RGARPRGK
Mvan_5999|M.vanbaalenii_PYR-1 --------
MSMEG_6258|M.smegmatis_MC2_155 --------
TH_3507|M.thermoresistible__bu --------