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M. tuberculosis H37Rv Rv0306 (-)

annotation: PUTATIVE OXIDOREDUCTASE
coordinates: 375914 - 376585
length: 223

MFSAPERRAVYRVIAERRDMRRFVPGGVVSEDVLARLLHAAHAAPSVGLMQPWRFIRITDETLKRRIHAL
VDDERLLTAEALGAREEEFLALKVEGILDCAELLVVALCDRRGSYIFGRRTLPQMDLASVSCAIQNLWLA
ARSEGLGMGWVSLFDPQRLAALLAMPADAEPVAILCLGPVPEFPDRPALELDGWAYARPLAEFVSENRWS
YPSALATDHHHGE
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0306--100% (223)PUTATIVE OXIDOREDUCTASE
M. tuberculosis H37RvRv3262fbiB1e-0627.68% (177) F420-0--gamma-glutamyl ligase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0314-1e-128100.00% (223) putative oxidoreductase
M. gilvum PYR-GCKMflv_0353-7e-4244.02% (209) cob(II)yrinic acid a,c-diamide reductase
M. leprae Br4923MLBr_00758-2e-0625.57% (176) F420-0--gamma-glutamyl ligase
M. abscessus ATCC 19977MAB_3351c-4e-3844.55% (202) putative nitroreductase
M. marinum MMMAR_0555-3e-9781.99% (211) oxidoreductase
M. avium 104MAV_4857bluB2e-9481.04% (211) cob(II)yrinic acid a,c-diamide reductase
M. smegmatis MC2 155MSMEG_6053bluB5e-9075.96% (208) cob(II)yrinic acid a,c-diamide reductase
M. thermoresistible (build 8)TH_1748-2e-8375.13% (197) PUTATIVE OXIDOREDUCTASE
M. ulcerans Agy99MUL_1218-6e-9781.52% (211) oxidoreductase
M. vanbaalenii PYR-1Mvan_0381-7e-3947.34% (188) cob(II)yrinic acid a,c-diamide reductase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0353|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0381|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_3351c|M.abscessus_ATCC_199      --------------------------------------------------
Rv0306|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0314|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0555|M.marinum_M               --------------------------------------------------
MUL_1218|M.ulcerans_Agy99           --------------------------------------------------
MAV_4857|M.avium_104                --------------------------------------------------
MSMEG_6053|M.smegmatis_MC2_155      --------------------------------------------------
TH_1748|M.thermoresistible__bu      --------------------------------------------------
MLBr_00758|M.leprae_Br4923          MTSSDSHRSAPSPEHGTASTIEILPVAGLPEFRPGDDLSAALAAAAPWLR
                                                                                      

Mflv_0353|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0381|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_3351c|M.abscessus_ATCC_199      --------------------------------------------------
Rv0306|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0314|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0555|M.marinum_M               --------------------------------------------------
MUL_1218|M.ulcerans_Agy99           --------------------------------------------------
MAV_4857|M.avium_104                --------------------------------------------------
MSMEG_6053|M.smegmatis_MC2_155      --------------------------------------------------
TH_1748|M.thermoresistible__bu      --------------------------------------------------
MLBr_00758|M.leprae_Br4923          DGDVVVVTSKVVSKCEGRLVPAPEDTRGRNELRRKLINDETIRVLARKGR
                                                                                      

Mflv_0353|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0381|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_3351c|M.abscessus_ATCC_199      --------------------------------------------------
Rv0306|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0314|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0555|M.marinum_M               --------------------------------------------------
MUL_1218|M.ulcerans_Agy99           --------------------------------------------------
MAV_4857|M.avium_104                --------------------------------------------------
MSMEG_6053|M.smegmatis_MC2_155      --------------------------------------------------
TH_1748|M.thermoresistible__bu      --------------------------------------------------
MLBr_00758|M.leprae_Br4923          TLIIENGLGLVQAAAGVDGSNVGRGELALLPVNPDASAAVLRIGLRAMLG
                                                                                      

Mflv_0353|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0381|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_3351c|M.abscessus_ATCC_199      --------------------------------------------------
Rv0306|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0314|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0555|M.marinum_M               --------------------------------------------------
MUL_1218|M.ulcerans_Agy99           --------------------------------------------------
MAV_4857|M.avium_104                --------------------------------------------------
MSMEG_6053|M.smegmatis_MC2_155      --------------------------------------------------
TH_1748|M.thermoresistible__bu      --------------------------------------------------
MLBr_00758|M.leprae_Br4923          VNVAVVITDTMGRAWRNGQTDVAIGAAGLAVLHNYSGAVDRYGNELVVTE
                                                                                      

Mflv_0353|M.gilvum_PYR-GCK          ----------------------------MS-AETAALYDVINRR------
Mvan_0381|M.vanbaalenii_PYR-1       ----------------------------MSDDSAAALYDVINRR------
MAB_3351c|M.abscessus_ATCC_199      ----------------------------------MDVYQAIATR------
Rv0306|M.tuberculosis_H37Rv         ---------------------------MFSAPERRAVYRVIAER------
Mb0314|M.bovis_AF2122/97            ---------------------------MFSAPERRAVYRVIAER------
MMAR_0555|M.marinum_M               -----------------------MADYAFTAQERQAVYRVITER------
MUL_1218|M.ulcerans_Agy99           -----------------------MTDYAFTAQERQAVYRVLTER------
MAV_4857|M.avium_104                -----------------------MTGPAFSPQERRAVYRVISER------
MSMEG_6053|M.smegmatis_MC2_155      -----------------------MPRHAFSPSERQAVYRAITER------
TH_1748|M.thermoresistible__bu      --------------------------------------------------
MLBr_00758|M.leprae_Br4923          IAVADEVAAATDLVKGKLTAMPVAVVRGLSPTDDGSTAQHLLRNGPDDLF
                                                                                      

Mflv_0353|M.gilvum_PYR-GCK          ------------------RDTRREFTGAPTDDEVLERVLLAAHAAPSVGM
Mvan_0381|M.vanbaalenii_PYR-1       ------------------RDTRREFTGEPVAGDVLQRVLLAAHAAPSVGM
MAB_3351c|M.abscessus_ATCC_199      ------------------RDVRAEFTGQVVDDATLMKLLQAAHRAPSVGN
Rv0306|M.tuberculosis_H37Rv         ------------------RDMRRFVPGGVVSEDVLARLLHAAHAAPSVGL
Mb0314|M.bovis_AF2122/97            ------------------RDMRRFVPGGVVSEDVLARLLHAAHAAPSVGL
MMAR_0555|M.marinum_M               ------------------RDMRRFVPGAMVPEDVLTRLLHAAHAAPNVGL
MUL_1218|M.ulcerans_Agy99           ------------------RDMRHFVPGAVVPEDVLTRLLHAAHAAPNVGL
MAV_4857|M.avium_104                ------------------RDMRRFVAGAVVDEQVLARLLAAAHAAPSVGL
MSMEG_6053|M.smegmatis_MC2_155      ------------------RDMRQFVPGSTVSDEVLSRLLHAAHAAPSVGL
TH_1748|M.thermoresistible__bu      --------------------MRRFIPGTTISDDVLKRLMHAAHAAPNVGL
MLBr_00758|M.leprae_Br4923          WLGTTEALELGRQQAQLLRRSVRQFSDEPIAAELIETAVAEALTAPAPHH
                                                            ...       :   :  *  **    

Mflv_0353|M.gilvum_PYR-GCK          SQPWDFVLVRSPETLRAFRDHVAGEREVFAAELSGERADVFDRIKIEGIC
Mvan_0381|M.vanbaalenii_PYR-1       SQPWDFILVRSPQTLTTFRDHVAAERETFAGELSGERAETFGRIKIEGIC
MAB_3351c|M.abscessus_ATCC_199      SQPWDFVVIREPGMLDDFAAHVALQRQRFADSLPEGRRNTFDPIKIEGIR
Rv0306|M.tuberculosis_H37Rv         MQPWRFIRITDETLKRRIHALVDDERLLTAEALG-AREEEFLALKVEGIL
Mb0314|M.bovis_AF2122/97            MQPWRFIRITDETLKRRIHALVDDERLLTAEALG-AREEEFLALKVEGIL
MMAR_0555|M.marinum_M               MQPWRFIRITDTGLRRRIHTLVDEERALTAGALG-ERAEEFLALKVEGIL
MUL_1218|M.ulcerans_Agy99           MQPWRFIRITDTGLRRRIHTLVDEERALTAGALG-ERAEEFLALKVEGIL
MAV_4857|M.avium_104                MQPWRFIRITDAALRRRIHALVEQERPRTAAALG-ERAQEFLALKVEGIL
MSMEG_6053|M.smegmatis_MC2_155      MQPWRFIRITDDTLRSRIHALVDEERVNTADALG-PRAQEFLALKVEGIR
TH_1748|M.thermoresistible__bu      MQPWRFIRITDPDLRRAIHRLVDEERHHTAAALG-PRGEEFLALKVEGIL
MLBr_00758|M.leprae_Br4923          TRPVRFVWLQTPAVRTRLLDRMADKWRLDLASDALPADAIAQRVARGQIL
                                     :*  *: :        :   :  :                  :    * 

Mflv_0353|M.gilvum_PYR-GCK          ESGLGIVVGYDP---TRGGPAVLGRHAIPDAGLYSVVCAIQNLWLAATAE
Mvan_0381|M.vanbaalenii_PYR-1       ESGLGIVVGYDP---TRAGPQVLGRHAVPDAGLYSVVCAIQNLWLAATVE
MAB_3351c|M.abscessus_ATCC_199      ESGTGVVVTYDH---GRGGPHILGRHTISDAGLFSAVLAIQNLWLAAVTE
Rv0306|M.tuberculosis_H37Rv         DCAELLVVALCD---RRGS-YIFGRRTLPQMDLASVSCAIQNLWLAARSE
Mb0314|M.bovis_AF2122/97            DCAELLVVALCD---RRGS-YIFGRRTLPQMDLASVSCAIQNLWLAARSE
MMAR_0555|M.marinum_M               ECAELMVVALRD---GRDG-HIFGRRTLPQMDLASVSCAIQNLWLAARAE
MUL_1218|M.ulcerans_Agy99           ECAELMVVALRD---GRDG-HIFGRRTLPQMDLASVSCAIQNLWLAARAE
MAV_4857|M.avium_104                ECAELLVVALGD---DRDK-HVFGRRTLPQMDLASVSCAIQNLWLAARAE
MSMEG_6053|M.smegmatis_MC2_155      ECAELFVVALGE---GRER-HVFGRRTLPNMDLASVSCAIQNMWLAARAE
TH_1748|M.thermoresistible__bu      ECAELLVVALGD---DRER-HIFGRRTMPDMDLASVSCAIQNLWLAARAE
MLBr_00758|M.leprae_Br4923          YDAPEVIIPFMVPDGAHAYPDAARASAEHTMFIVAVGAAVQALLVALAVR
                                      .  .::        :         :     : :.  *:* : :*   .

Mflv_0353|M.gilvum_PYR-GCK          GLGVGWVS--FYREETLRSLVGMPDHVRPVAWLCVGPVADLPDVPDLERF
Mvan_0381|M.vanbaalenii_PYR-1       GLGVGWVS--FYREEFLRSLVGMPDHVRPVAWLCVGPVAELPDVPDLERF
MAB_3351c|M.abscessus_ATCC_199      GIGVGWVS--FYEEQFLAELIDAPAHIRPIAWLCVGPVREFAERPDLERF
Rv0306|M.tuberculosis_H37Rv         GLGMGWVS--LFDPQRLAALLAMPADAEPVAILCLGPVPEFPDRPALELD
Mb0314|M.bovis_AF2122/97            GLGMGWVS--LFDPQRLAALLAMPADAEPVAILCLGPVPEFPDRPALELD
MMAR_0555|M.marinum_M               GLGMGWVS--LFDPHRLADLLRMPDGAEPVAVLCLGPVPEFPQQPALELD
MUL_1218|M.ulcerans_Agy99           GLGMGWVS--LFDPHRLADLLRMPDGAEPVAVLCLGPVPEFPQQPALELD
MAV_4857|M.avium_104                GLGMGWVS--LFEPRPLAELLGLPDGAEPVAILCLGPVPEFPDRPALELD
MSMEG_6053|M.smegmatis_MC2_155      GLGMGWVS--IFEPQPLAELLGMPDGAEPVAILCLGPVPEFPDRPVLEIE
TH_1748|M.thermoresistible__bu      GLGMGWVS--LFEPRRLATLLDIPADAEPVAVLCLGPVPDFPDRPELEIE
MLBr_00758|M.leprae_Br4923          GLGSCWIGSTIFADDLVRAELELPADWEPLGAIAIG----YAHEP----T
                                    *:*  *:.  ::    :   :  *   .*:. :.:*     .. *     

Mflv_0353|M.gilvum_PYR-GCK          GWQARRSLDTVVHRERYPEP-----------
Mvan_0381|M.vanbaalenii_PYR-1       GWRARSSLETVLHQECYRAR-----------
MAB_3351c|M.abscessus_ATCC_199      GWRTGRPLEDAVHWGRYRA------------
Rv0306|M.tuberculosis_H37Rv         GWAYARPLAEFVSENRWSYPSALATDHHHGE
Mb0314|M.bovis_AF2122/97            GWAYARPLAEFVSENRWSYPSALATDHHHGE
MMAR_0555|M.marinum_M               GWAVARPLPEFVSENRWDQP-----------
MUL_1218|M.ulcerans_Agy99           GWAVARPLPEFVSENRWDQP-----------
MAV_4857|M.avium_104                GWATPRPLAEFVCENRWAQPQLP--------
MSMEG_6053|M.smegmatis_MC2_155      HWTTGRPLPEFVSENGWPEHASV--------
TH_1748|M.thermoresistible__bu      NWTVGRPLDEFVSENGWTDSGARA-------
MLBr_00758|M.leprae_Br4923          DLREPVRVADLLLRK----------------
                                           :   :