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VGELLAGIRAQRACRRFDPDGKVPDSDVEQMLAASVHAPSAENSQPWTFIVVRDDGNRALLASWWTETWN AGGGDFVKQSVEDKVLVADLEFGFSKGGFAAAPVVIVVCADTDRVPEIYAPSSIYPAVQNMLLAAADLGY GSCLTTGLTTFGVDRVRELLQLPQNLIPMAAVYVGLPARKLSPPRRRPATSVTYREAFGNPW
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2661 | - | - | 100% (202) | nitroreductase |
| M. avium 104 | MAV_1962 | - | 2e-95 | 80.20% (202) | NADPH nitroreductase |
| M. avium 104 | MAV_0933 | - | 3e-14 | 30.98% (184) | nitroreductase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3403c | - | 4e-09 | 27.27% (220) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3382 | - | 3e-22 | 33.64% (214) | nitroreductase |
| M. tuberculosis H37Rv | Rv3368c | - | 4e-09 | 27.27% (220) | oxidoreductase |
| M. leprae Br4923 | MLBr_00758 | - | 1e-05 | 25.57% (176) | F420-0--gamma-glutamyl ligase |
| M. abscessus ATCC 19977 | MAB_3693c | - | 8e-12 | 27.87% (183) | oxidoreductase |
| M. marinum M | MMAR_2938 | - | 2e-19 | 33.83% (201) | nitroreductase |
| M. smegmatis MC2 155 | MSMEG_5155 | - | 2e-11 | 27.31% (216) | nitroreductase |
| M. thermoresistible (build 8) | TH_2448 | - | 1e-22 | 32.86% (210) | PUTATIVE nitroreductase |
| M. ulcerans Agy99 | MUL_2198 | - | 5e-20 | 33.83% (201) | nitroreductase |
| M. vanbaalenii PYR-1 | Mvan_3115 | - | 2e-19 | 29.86% (211) | nitroreductase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_2448|M.thermoresistible__bu --------------------------------------------------
Mvan_3115|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3382|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2938|M.marinum_M --------------------------------------------------
MUL_2198|M.ulcerans_Agy99 --------------------------------------------------
MAV_2661|M.avium_104 --------------------------------------------------
Mb3403c|M.bovis_AF2122/97 --------------------------------------------------
Rv3368c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3693c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5155|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00758|M.leprae_Br4923 MTSSDSHRSAPSPEHGTASTIEILPVAGLPEFRPGDDLSAALAAAAPWLR
TH_2448|M.thermoresistible__bu --------------------------------------------------
Mvan_3115|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3382|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2938|M.marinum_M --------------------------------------------------
MUL_2198|M.ulcerans_Agy99 --------------------------------------------------
MAV_2661|M.avium_104 --------------------------------------------------
Mb3403c|M.bovis_AF2122/97 --------------------------------------------------
Rv3368c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3693c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5155|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00758|M.leprae_Br4923 DGDVVVVTSKVVSKCEGRLVPAPEDTRGRNELRRKLINDETIRVLARKGR
TH_2448|M.thermoresistible__bu --------------------------------------------------
Mvan_3115|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3382|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2938|M.marinum_M --------------------------------------------------
MUL_2198|M.ulcerans_Agy99 --------------------------------------------------
MAV_2661|M.avium_104 --------------------------------------------------
Mb3403c|M.bovis_AF2122/97 --------------------------------------------------
Rv3368c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3693c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5155|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00758|M.leprae_Br4923 TLIIENGLGLVQAAAGVDGSNVGRGELALLPVNPDASAAVLRIGLRAMLG
TH_2448|M.thermoresistible__bu --------------------------------------------------
Mvan_3115|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3382|M.gilvum_PYR-GCK --------------------------------------------------
MMAR_2938|M.marinum_M --------------------------------------------------
MUL_2198|M.ulcerans_Agy99 --------------------------------------------------
MAV_2661|M.avium_104 --------------------------------------------------
Mb3403c|M.bovis_AF2122/97 --------------------------------------------------
Rv3368c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_3693c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_5155|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00758|M.leprae_Br4923 VNVAVVITDTMGRAWRNGQTDVAIGAAGLAVLHNYSGAVDRYGNELVVTE
TH_2448|M.thermoresistible__bu ----------MPDTPKPIPSVAEALARLDMPLAEAMMTQRAVR-------
Mvan_3115|M.vanbaalenii_PYR-1 -------------MPEPIPSAAEALARLDMPLVEAMMTQRAIR-------
Mflv_3382|M.gilvum_PYR-GCK -------------MADPTPSTSEALARLDMSLIDVMMTQRAVR-------
MMAR_2938|M.marinum_M -----------------------------MPLEDAMRTQRSIR-------
MUL_2198|M.ulcerans_Agy99 -----------------------------MPLEDAMRTQRSIR-------
MAV_2661|M.avium_104 ----------------------------MGELLAGIRAQRACR-------
Mb3403c|M.bovis_AF2122/97 ------------------------MT-LNLSVDEVLTTTRSVRK------
Rv3368c|M.tuberculosis_H37Rv ------------------------MT-LNLSVDEVLTTTRSVRK------
MAB_3693c|M.abscessus_ATCC_199 ------------------------MTSLNLSADEVLTTTRSVRK------
MSMEG_5155|M.smegmatis_MC2_155 -----------------------------MEFTDVVRTTAAIR-------
MLBr_00758|M.leprae_Br4923 IAVADEVAAATDLVKGKLTAMPVAVVRGLSPTDDGSTAQHLLRNGPDDLF
: *
TH_2448|M.thermoresistible__bu ----------------------RVLPD-PVDDELVLKCIELALRAPTGSN
Mvan_3115|M.vanbaalenii_PYR-1 ----------------------RVLPD-PVDDEIVLKCLELALRAPTGAN
Mflv_3382|M.gilvum_PYR-GCK ----------------------RVYPD-PVDDEIVMKCLEVALHAPTGAN
MMAR_2938|M.marinum_M ----------------------RLKSD-PVDDSLVLHLLELAMKAPTGSN
MUL_2198|M.ulcerans_Agy99 ----------------------RLKSD-PVDDSLVLHLLELAMKAPTGSN
MAV_2661|M.avium_104 ----------------------RFDPDGKVPDSDVEQMLAASVHAPSAEN
Mb3403c|M.bovis_AF2122/97 ----------------------RLDFDKPVPRDVLMECLELALQAPTGSN
Rv3368c|M.tuberculosis_H37Rv ----------------------RLDFDKPVPRDVLMECLELALQAPTGSN
MAB_3693c|M.abscessus_ATCC_199 ----------------------RLDFDKPVERAVVEECLNIAMQAPTGSN
MSMEG_5155|M.smegmatis_MC2_155 ----------------------QFTGD-PLPDDVLRRILDNARFAPSGGN
MLBr_00758|M.leprae_Br4923 WLGTTEALELGRQQAQLLRRSVRQFSDEPIAAELIETAVAEALTAPAPHH
: * : : : : **: :
TH_2448|M.thermoresistible__bu GQNWEFIVVKDPAVKAKLADRYRQAWAVYGGIGRR-VTAG---DESMAKI
Mvan_3115|M.vanbaalenii_PYR-1 GQNWEFVVVKDPKIKRKLQRRYRLAWRVFHRTSIRDIASY---DEEMAKS
Mflv_3382|M.gilvum_PYR-GCK GQNWEFIVVKDYETKKKLAKRYRQAWNLYYQTVIRRVSKR---DPSMAKT
MMAR_2938|M.marinum_M AQNWEFIVVKDREVVAKLGRLNRRAMQLFGPIYRRSIARRG--DEKMLRL
MUL_2198|M.ulcerans_Agy99 AQNWEFIVVKDREVVAKLGRLNRRAMQLFGPIYRRSIARRG--DEKMLRL
MAV_2661|M.avium_104 SQPWTFIVVRDDGNRALLASWWTETWNAGGGDFVKQSVED-----KVLVA
Mb3403c|M.bovis_AF2122/97 SQGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDGDTRGERMGRV
Rv3368c|M.tuberculosis_H37Rv SQGWQWVFVEDAAKKKAIADVYLANARGYLSGPAPEYPDGDTRGERMGRV
MAB_3693c|M.abscessus_ATCC_199 HQGWHWVIVEDAEKKKAIADIYREGWNKYAKGAGATYAEGDTRAERKAKV
MSMEG_5155|M.smegmatis_MC2_155 RQGTRVVVIRDRDTREALAELTITGSRRYIAQKRIGENPWNPLHPTAVTE
MLBr_00758|M.leprae_Br4923 TRPVRFVWLQTPAVRTRLLDRMADKWRLDLA--------------SDALP
: : :. :
TH_2448|M.thermoresistible__bu LRAVQWQV---DHFTEIPVLVVACLRAGPREGRLPFMPAPPVAASSFFGS
Mvan_3115|M.vanbaalenii_PYR-1 VRAIEWQL---EHFHEIPVLVIACLRLSAREGKVPYVPMPHAAASAFFGS
Mflv_3382|M.gilvum_PYR-GCK ARAVQWQV---DHFTEVPVLIVACLKLGPKDGRIPFVPMPHAALSGFYGS
MMAR_2938|M.marinum_M QKAVQWQA---DHFEEIPVVVVACLRG-------VIAPWPRISTSSAYGS
MUL_2198|M.ulcerans_Agy99 QKAVQWQA---DHFEEIPVVVVACLRG-------VIAPWPRISTSSAYGS
MAV_2661|M.avium_104 DLEFGFSK---GGFAAAPVVIVVCADT------------DRVPEIYAPSS
Mb3403c|M.bovis_AF2122/97 RDSATYLA---EHMHRAPVLLIPCLKG-------RED-ESAVGGVSFWAS
Rv3368c|M.tuberculosis_H37Rv RDSATYLA---EHMHRAPVLLIPCLKG-------RED-ESAVGGVSFWAS
MAB_3693c|M.abscessus_ATCC_199 VDSAGYLA---ENFERSPLFLIPCIEG-------RLDNLPVVGAASSWGS
MSMEG_5155|M.smegmatis_MC2_155 ADLAAVDVPRATPLLDAAVVLVVCVDLG---VVAAFDQDLDRIGVVSGAS
MLBr_00758|M.leprae_Br4923 ADAIAQRVARGQILYDAPEVIIPFMVPDG-AHAYPDAARASAEHTMFIVA
: . .:: :
TH_2448|M.thermoresistible__bu IYPSVQNLLLAARAMGLGASLIT--LPLWSMTSARRILKLPLSVTP-CCI
Mvan_3115|M.vanbaalenii_PYR-1 IYPSVQNLLLAARAMGLGASLIT--LPLWNLTSARRVLKLPTEVTP-CCV
Mflv_3382|M.gilvum_PYR-GCK IYPSVQNLLLAARAMGLGASLIT--LPLWSVTSTRKTLGLPVSVTP-CCV
MMAR_2938|M.marinum_M IYPAVQNLLLAARAAGLGAGLIT--VPLWSTVLARRALGLPWNVTP-CAV
MUL_2198|M.ulcerans_Agy99 IYPAVQNLLLAARAAGLGAGLIT--VPLWSTVLARRALGLPRNVTP-CAV
MAV_2661|M.avium_104 IYPAVQNMLLAAADLGYGSCLTTG-LTTFGVDRVRELLQLPQNLIP-MAA
Mb3403c|M.bovis_AF2122/97 LFPAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGL
Rv3368c|M.tuberculosis_H37Rv LFPAVWSFCLALRSRGLGSCWTTLHLLDNGEHKVADVLGIPYDEYSQGGL
MAB_3693c|M.abscessus_ATCC_199 LLPAVWSFMLAARNRGLGSAWTTLHLMDDGEKRTADIVGIPFDKVTQGGL
MSMEG_5155|M.smegmatis_MC2_155 VYPFVWNILLSARNEGFGGVLTT--MAIAEEPKVKELLAIPDDYAV-AAV
MLBr_00758|M.leprae_Br4923 VGAAVQALLVALAVRGLGSCWIG--STIFADDLVRAELELPADWEP-LGA
: . * : :: * *. . : :* .
TH_2448|M.thermoresistible__bu VPLGWPRGR-YGPTTRRPVREVVHLDSYGNRAWQSPS-----
Mvan_3115|M.vanbaalenii_PYR-1 VPLGWPRGR-YGPTTRRPVDEVVHLDRYGNRAWFGPRGADRP
Mflv_3382|M.gilvum_PYR-GCK VPLGWPRGR-YGPTTRRPVAEVMHLNTYGNRPWMGTG-----
MMAR_2938|M.marinum_M VPLGWPIGK-YGPTTRRPVAEIVSLDRYGNRAFR--------
MUL_2198|M.ulcerans_Agy99 VPLGWPIGK-YGPTTRRPVAEIVSLDRYGNRAFR--------
MAV_2661|M.avium_104 VYVGLPARK-LSPPRRRPATSVTYREAFGN-PW---------
Mb3403c|M.bovis_AF2122/97 LPIAYTQGIDFRPAKRLPAESVTHWNGW--------------
Rv3368c|M.tuberculosis_H37Rv LPIAYTQGIDFRPAKRLPAESVTHWNGW--------------
MAB_3693c|M.abscessus_ATCC_199 FPIAYTVGTDFRLAKRQPLADVLHWDTW--------------
MSMEG_5155|M.smegmatis_MC2_155 LPLGKPVHQ-PTKLTRKPVSEIATRERFDGAPF---------
MLBr_00758|M.leprae_Br4923 IAIGYAHEP---TDLREPVRVADLLLRK--------------
. :. . * *