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VGISRASGTAEAALMKALYDEHAAVLWRYALRLTGDASQSEDVVQETLLRAWQHPEVIGDTERSARAWLF TVARNMIIDDRRSARFRNVVGSTDTAGAPEQSTPDEVNAALDRLLIADAMAQLSAEHRAVIERSYYRGWT TAQIATDLGIAEGTVKSRLHYAVRALRLTLQELGVTR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4431 | - | - | 100% (178) | RNA polymerase sigma factor SigL |
| M. avium 104 | MAV_1365 | - | 6e-11 | 30.97% (155) | RNA polymerase sigma-70 factor |
| M. avium 104 | MAV_4415 | - | 2e-09 | 27.56% (156) | RNA polymerase sigma factor, sigma-70 family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0756 | sigL | 4e-87 | 89.83% (177) | RNA polymerase sigma factor SigL |
| M. gilvum PYR-GCK | Mflv_5019 | - | 2e-65 | 70.24% (168) | RNA polymerase sigma factor SigL |
| M. tuberculosis H37Rv | Rv0735 | sigL | 4e-87 | 89.83% (177) | RNA polymerase sigma factor SigL |
| M. leprae Br4923 | MLBr_01076 | sigE | 5e-11 | 29.89% (174) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_2163 | - | 4e-51 | 57.67% (163) | ECF subfamily RNA polymerase sigma factor |
| M. marinum M | MMAR_1073 | sigL | 3e-80 | 87.06% (170) | alternative RNA polymerase sigma factor (RpoE), SigL |
| M. smegmatis MC2 155 | MSMEG_1486 | - | 1e-58 | 64.77% (176) | RNA polymerase sigma factor SigL |
| M. thermoresistible (build 8) | TH_1898 | - | 5e-11 | 31.13% (151) | RNA polymerase ECF-type sigma factor |
| M. ulcerans Agy99 | MUL_0831 | sigL | 3e-79 | 85.88% (170) | RNA polymerase sigma factor SigL |
| M. vanbaalenii PYR-1 | Mvan_1350 | - | 1e-67 | 71.26% (167) | RNA polymerase sigma factor SigL |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5019|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1350|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1486|M.smegmatis_MC2_155 --------------------------------------------------
Mb0756|M.bovis_AF2122/97 --------------------------------------------------
Rv0735|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4431|M.avium_104 --------------------------------------------------
MMAR_1073|M.marinum_M --------------------------------------------------
MUL_0831|M.ulcerans_Agy99 --------------------------------------------------
MAB_2163|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_01076|M.leprae_Br4923 MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLLSPT
TH_1898|M.thermoresistible__bu --------------------------------------------------
Mflv_5019|M.gilvum_PYR-GCK ----------------------ME-------DADAAMMRVLYDEHAAALW
Mvan_1350|M.vanbaalenii_PYR-1 ----------------------MD-------DPEAAMMRVLYDEHAAALW
MSMEG_1486|M.smegmatis_MC2_155 ----------------------ME-------DPEAAMMRALYDEHATALW
Mb0756|M.bovis_AF2122/97 ----------------------MARVSGAA-AAEAALMRALYDEHAAVLW
Rv0735|M.tuberculosis_H37Rv ----------------------MARVSGAA-AAEAALMRALYDEHAAVLW
MAV_4431|M.avium_104 ----------------------MVGISRASGTAEAALMKALYDEHAAVLW
MMAR_1073|M.marinum_M ----------------------MARVAGGG-AAEAALMQALYDEHAAVLW
MUL_0831|M.ulcerans_Agy99 ----------------------MARVAGGG-AAEAALMQALYDEHAAVLW
MAB_2163|M.abscessus_ATCC_1997 -------------------------------------MRAFYDEYAGPLH
MLBr_01076|M.leprae_Br4923 IMSHPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSWEELVRQHAARVY
TH_1898|M.thermoresistible__bu ------------------------VSVEPDPQPAPQALLDLYDEALPVVY
: : :
Mflv_5019|M.gilvum_PYR-GCK RYALRLTGDRARSEDVVQETLLRAWRHP---------GVIADVDRPARAW
Mvan_1350|M.vanbaalenii_PYR-1 RYALRLTGDRARAEDVVQETLLRAWRHP---------EVTADVDRSARAW
MSMEG_1486|M.smegmatis_MC2_155 RYALRLTGDPARAEDVVQETLLRAWRHQPDLRTGGGADGIAGPDRSPRAW
Mb0756|M.bovis_AF2122/97 RYALRLTGDAAQAEDVVQETLLRAWQHP---------EVIGDTARPARAW
Rv0735|M.tuberculosis_H37Rv RYALRLTGDAAQAEDVVQETLLRAWQHP---------EVIGDTARPARAW
MAV_4431|M.avium_104 RYALRLTGDASQSEDVVQETLLRAWQHP---------EVIGDTERSARAW
MMAR_1073|M.marinum_M RYAMRLTSDASYADDIVQETLLRAWQHP---------EVIDERGRSARAW
MUL_0831|M.ulcerans_Agy99 RYTMRLTSDASYADDIVQETLLRAWQHP---------EVIDERGRSARAW
MAB_2163|M.abscessus_ATCC_1997 RYVMHLTHDSALAEDIVQEVLLRAWRHP---------TLVNQTEGSARAW
MLBr_01076|M.leprae_Br4923 WLAYRLSGNQHDAEDLTQETFIRVFRSV-----------QNYQPGTFEGW
TH_1898|M.thermoresistible__bu GYFVRRCADRATAEDLTSETFLAAMDAA----------HRDAHTPISVPW
: : ::*:..*.:: . *
Mflv_5019|M.gilvum_PYR-GCK LFTVARNMIIDERRSARFRHETGVPDPEHVAEPASPDEADPTLDRIL---
Mvan_1350|M.vanbaalenii_PYR-1 LFTVARNMIIDERRSARFKHESGVADTEYVPDSASPDEADTALDRIL---
MSMEG_1486|M.smegmatis_MC2_155 LFTVARNMIIDERRSARFRNETDVPDPEQVADHATSDQVDTALDRLL---
Mb0756|M.bovis_AF2122/97 LFTVARNMIIDERRSARFRNVVGSTDQSGTPEQSTPDEVNAALDRLL---
Rv0735|M.tuberculosis_H37Rv LFTVARNMIIDERRSARFRNVVGSTDQSGTPEQSTPDEVNAALDRLL---
MAV_4431|M.avium_104 LFTVARNMIIDDRRSARFRNVVGSTDTAGAPEQSTPDEVNAALDRLL---
MMAR_1073|M.marinum_M LFTVARNMIIDDRRSARYRYVVSSTDADGAPEQSTPDEVGAALDRLL---
MUL_0831|M.ulcerans_Agy99 LFTVARNMIIDDRRSARYRYVVSSTDADGAPEQSTPDEVGAALGRLL---
MAB_2163|M.abscessus_ATCC_1997 LFTVAHNLVRDNARSSRFRSEIATAET---PEFASPDQVDATLDAWL---
MLBr_01076|M.leprae_Br4923 LHRITTNLFLDMVRRRARIRMDALPDDYDRVPADEPNPEQIYHDSRLGPD
TH_1898|M.thermoresistible__bu LIGVARHKLADHYRRRHHRQSVSVAEVPEPDEPT--DQWDAELDRIV---
* :: : . * * .: : . :
Mflv_5019|M.gilvum_PYR-GCK LGTALRQLSDEHRAVVRRAYYQGWTTGQIAADLQIPEGTVKSRLHYAVRA
Mvan_1350|M.vanbaalenii_PYR-1 LSTALSQLSDEHRAVVRRAYYQGWTTGQIAADLNIPEGTVKSRLHYAVRA
MSMEG_1486|M.smegmatis_MC2_155 LGTALRQLSDDHRAVIRRAYYQGLTTGQIAAELQIPEGTVKSRLHYAVRA
Mb0756|M.bovis_AF2122/97 IADALAQLSAEHRAVIQRSYYRGWSTAQIATDLGIAEGTVKSRLHYAVRA
Rv0735|M.tuberculosis_H37Rv IADALAQLSAEHRAVIQRSYYRGWSTAQIATDLGIAEGTVKSRLHYAVRA
MAV_4431|M.avium_104 IADAMAQLSAEHRAVIERSYYRGWTTAQIATDLGIAEGTVKSRLHYAVRA
MMAR_1073|M.marinum_M IADALAQLSGEHRAVIERSYYRGWTTAQIAKDLEIAEGTVKSRLHYAVRA
MUL_0831|M.ulcerans_Agy99 IADALAQLSGEHRAVIERSYYRGWTTAQIAKDLEIAEGTVKSRLHYAVRA
MAB_2163|M.abscessus_ATCC_1997 VAEALRTLSTDHRAVILRAYYRGSSVADISAELGVPEGTVKSRLHYGVRA
MLBr_01076|M.leprae_Br4923 LQAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQA
TH_1898|M.thermoresistible__bu AESVLARLPDQHRTVLALRYLDDCSVPECAHLIGRTVHATEALLVRARRA
.: *. :.*:.: . : : . : :..: : . :*
Mflv_5019|M.gilvum_PYR-GCK LKLGLQEMGVTR------------
Mvan_1350|M.vanbaalenii_PYR-1 LKLGLQEMGVTR------------
MSMEG_1486|M.smegmatis_MC2_155 LKLSLQEMGVTR------------
Mb0756|M.bovis_AF2122/97 LRLTLQELGVTR------------
Rv0735|M.tuberculosis_H37Rv LRLTLQELGVTR------------
MAV_4431|M.avium_104 LRLTLQELGVTR------------
MMAR_1073|M.marinum_M LRLTLQELGVTR------------
MUL_0831|M.ulcerans_Agy99 LRLTLQELGVTR------------
MAB_2163|M.abscessus_ATCC_1997 LRLSLQEMGVTR------------
MLBr_01076|M.leprae_Br4923 LRDYLLTAHPRDGATTDATHVKSA
TH_1898|M.thermoresistible__bu FRRAYPDREGGTS-----------
::