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VRHGVGVAQHTFAMTDPFLGSEALAARLLSRHELRSRYVALHRDVYVARDAELTAVVRAKAAWLRSRRRG VLAGFSAAALHGSKWIDAARPAEIIDTNRRHARGVRVWEERIESDEITVVDGTAVTTPARTALDLARRHP RGVAVAAIDALVQATELKMADVELLVDRYRGRHDIKAARAALALVDGGAQSPKESWLRVLLIDAGFPRPQ TQIAVRNEWGWAEAYLDMGWEEIKVAAEYDGDQHRASRYQYVKDIRRLEMLERYGWIVVRVIAEDRPDEI IRRVHDARRRRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3296 | - | - | 100% (292) | hypothetical protein MAV_3296 |
| M. avium 104 | MAV_3351 | - | 1e-89 | 57.91% (278) | hypothetical protein MAV_3351 |
| M. avium 104 | MAV_0642 | - | 8e-87 | 58.06% (279) | hypothetical protein MAV_0642 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1518c | - | 1e-115 | 73.57% (280) | hypothetical protein Mb1518c |
| M. gilvum PYR-GCK | Mflv_4708 | - | 2e-76 | 52.88% (278) | hypothetical protein Mflv_4708 |
| M. tuberculosis H37Rv | Rv1482c | - | 1e-115 | 73.57% (280) | hypothetical protein Rv1482c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1570 | - | 1e-88 | 59.35% (278) | hypothetical protein MAB_1570 |
| M. marinum M | MMAR_5026 | - | 1e-82 | 54.84% (279) | hypothetical protein MMAR_5026 |
| M. smegmatis MC2 155 | MSMEG_5917 | - | 1e-82 | 55.47% (274) | hypothetical protein MSMEG_5917 |
| M. thermoresistible (build 8) | TH_1775 | - | 6e-83 | 53.26% (276) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4737 | - | 3e-70 | 51.09% (276) | hypothetical protein MUL_4737 |
| M. vanbaalenii PYR-1 | Mvan_5526 | - | 3e-63 | 48.20% (278) | hypothetical protein Mvan_5526 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1518c|M.bovis_AF2122/97 -------------MTDPFLGSEALAAGVLTPYELRSRYVALHKDVYVPQG
Rv1482c|M.tuberculosis_H37Rv -------------MTDPFLGSEALAAGVLTPYELRSRYVALHKDVYVPQG
MAV_3296|M.avium_104 MRHGVGVAQHTFAMTDPFLGSEALAARLLSRHELRSRYVALHRDVYVARD
Mflv_4708|M.gilvum_PYR-GCK -------------MGEPFIGSEALRAGRLTRHQLRTAHIAVYPDVYVPVA
MSMEG_5917|M.smegmatis_MC2_155 -------------MGDPVIGTEAVAAGFATPYQLRSRYWPVYPGIYVPKD
TH_1775|M.thermoresistible__bu ---------MAAPFSEPFLGSEALTSGALTRHQLRTRYRAIHRDVYIAND
MAB_1570|M.abscessus_ATCC_1997 -------------MGEPFVGSEAVRSGRLTAYALRTRYVAIHPDVYLPRG
MMAR_5026|M.marinum_M -------------MAVPFLGSEAVASGEVRKSALRTRYHRLFPDVYIRCD
MUL_4737|M.ulcerans_Agy99 ---MDAREARAARSEDVFVGSGAVRRGRLSPYRLRTEFRAIYPDVYLPAH
Mvan_5526|M.vanbaalenii_PYR-1 ----------MPGMGEVILGGEAVRAGVVTRHELARWYTPLYRGVFVRKG
.:* *: * . :. .:::
Mb1518c|M.bovis_AF2122/97 VELTAQLRAKALWLRSRRRGVLAGYSASAFHGAKWIDADLPAAIIDTNRR
Rv1482c|M.tuberculosis_H37Rv VELTAQLRAKALWLRSRRRGVLAGYSASAFHGAKWIDADLPAAIIDTNRR
MAV_3296|M.avium_104 AELTAVVRAKAAWLRSRRRGVLAGFSAAALHGSKWIDAARPAEIIDTNRR
Mflv_4708|M.gilvum_PYR-GCK TTLTAVAKAKAASLWTGREGIIAGQSAAAIHGARWVDARRPAEVLWHNRR
MSMEG_5917|M.smegmatis_MC2_155 TQPTAALRAKAAWLWSDRRAVLAGRSASALHRSRWLDPRAPAELIHDNRR
TH_1775|M.thermoresistible__bu AELDAVLRAKACWLRSRGHGVLAGFSASALHGAKYVDPRRPATVIDTNRR
MAB_1570|M.abscessus_ATCC_1997 AQLTPLVRAQASWLWTGRRGILAGHSASALHGARWIDAARNAEIVHDNRH
MMAR_5026|M.marinum_M AELSPQARARAGWLWSRRRGIVAGLAASALHGARWVDPDAPLDILHVNRN
MUL_4737|M.ulcerans_Agy99 AAPSFRTRCKAAWLWTGRRGVLGGLAAAGLHGSDWIGDDEPVELIWRNPH
Mvan_5526|M.vanbaalenii_PYR-1 VEVTLRDRAVGAWLATGRKGVIAGLAAAALHGAAWIDADIPIEVAGVKRR
. :. . * : ..::.* :*:.:* : ::. : : .
Mb1518c|M.bovis_AF2122/97 RAPGLQVWEERIEPDEICVIEGMRVTTPERTALDLTSRFPLDPAVAAVDA
Rv1482c|M.tuberculosis_H37Rv RAPGLQVWEERIEPDEICVIEGMRVTTPERTALDLTSRFPLDPAVAAVDA
MAV_3296|M.avium_104 HARGVRVWEERIESDEITVVDGTAVTTPARTALDLARRHPRGVAVAAIDA
Mflv_4708|M.gilvum_PYR-GCK APRGVLVWSDRVADDEVTTVRGVRVTTPERTALDIACRYPQRRAVAAIDA
MSMEG_5917|M.smegmatis_MC2_155 PPCGIKTWLDRFEDDEITVVDGIRVTTPARTAVDLACRYPLDTAVTLIDA
TH_1775|M.thermoresistible__bu RTPGILTWGHTLDEDEICEIDGMRLTTPARTAVDLACRYPVGTSVAAIDA
MAB_1570|M.abscessus_ATCC_1997 RQPGITVWSGEIAPDEICVVRGMRATTAARTALDLACRCPRGRAVAAIDA
MMAR_5026|M.marinum_M PRPGIRARGDRIATDEVMQIGGIPVTTPARTALDLGCWYPTGEAVAAIDS
MUL_4737|M.ulcerans_Agy99 PPAGVITRNQRIEPDEVTRVAGLAVTTLARTAFDLGRQLPGGESVARLDA
Mvan_5526|M.vanbaalenii_PYR-1 SHAGLITRSEVIATDEIVRRAGLPVTSRTRTAFDLGRQLDRAEALARLDA
*: . . **: * *: ***.*: ::: :*:
Mb1518c|M.bovis_AF2122/97 LIQATDLKVADVEPLIERYRGRRGMKAARAALDLVDGGAQSPKETWLRLL
Rv1482c|M.tuberculosis_H37Rv LIQATDLKVADVEPLIERYRGRRGMKAARAALDLVDGGAQSPKETWLRLL
MAV_3296|M.avium_104 LVQATELKMADVELLVDRYRGRHDIKAARAALALVDGGAQSPKESWLRVL
Mflv_4708|M.gilvum_PYR-GCK LARAAHMKLADVELLVDRHTGRRGIRAARAALNLVDPGAESPQETYLRLT
MSMEG_5917|M.smegmatis_MC2_155 LGNATRLKMADVELLVDRYRGRRGIKNARHVLDLVDGGAESPRETWLRLE
TH_1775|M.thermoresistible__bu LARAARLKVADIEAAAQRHPGRHGLRRAREAIALVDPGAESPRETALRLL
MAB_1570|M.abscessus_ATCC_1997 LCRATELQISEALELASRHAGMRGIRRARTAFELVDAGAQSPKETWLRLL
MMAR_5026|M.marinum_M LMRAADVGRAQIETLLHRYPTRRWIRRARRAVERADPGAQSPKETWLRLL
MUL_4737|M.ulcerans_Agy99 LMRATAFSGEDVLLLAKRYSGARGLRRLRATLPLVDAGAASPRESWLRMV
Mvan_5526|M.vanbaalenii_PYR-1 LMWNQPFSIDEVAELADRRPRVPGVGQLRDLLPLIDGGAASPRQSRLRLW
* . : * : * . * ** **::: **:
Mb1518c|M.bovis_AF2122/97 LIRAGFPRPQTQIAVRNEWGWAEAHLDMGWQDIKVAAEYDGDHHLTSRYH
Rv1482c|M.tuberculosis_H37Rv LIRAGFPRPQTQIAVRNEWGWAEAHLDMGWQDIKVAAEYDGDHHLTSRYH
MAV_3296|M.avium_104 LIDAGFPRPQTQIAVRNEWGWAEAYLDMGWEEIKVAAEYDGDQHRASRYQ
Mflv_4708|M.gilvum_PYR-GCK VIGNHFPPPQTQIPVWD-CGALVAELDMGWEHMMIGLDYEGDHHRTTREA
MSMEG_5917|M.smegmatis_MC2_155 VIRGGFPRPQTQIPVHDEYGVLVGVFDMGWEDAMVGLDYEGDQHRTDRRR
TH_1775|M.thermoresistible__bu IVRAGYPPPETQLPIHNEFGVLIGVVDMGWRDRRIAVEYEGRHHFTSRRA
MAB_1570|M.abscessus_ATCC_1997 LRDAGLPPVSTQILVHNGDFVALAYIDMGWEDVMVGIEYDGDQHRSDRRQ
MMAR_5026|M.marinum_M LLDDGLPRPQTQIRVADEWGELVAYLDMGWEELMVAVEYDGEQHRNDRRQ
MUL_4737|M.ulcerans_Agy99 LIDAGLPVPVTQIPVHQ-NWRLVAVLDMGWQKYQVAAEYDGDQHRFDRRQ
Mvan_5526|M.vanbaalenii_PYR-1 LLDCGFPRPQTQIPVLE-GSRPVAFLDMGWPEYQVAVEYDGDHHRKNRDQ
: * **: : : . .**** . :. :*:* :* *
Mb1518c|M.bovis_AF2122/97 YRKDILRHEKVQHRYGWIVVRVVAEDHPADIIRRVGEARAFRA-------
Rv1482c|M.tuberculosis_H37Rv YRKDILRHEKVQHRYGWIVVRVVAEDHPADIIRRVGEARAFRA-------
MAV_3296|M.avium_104 YVKDIRRLEMLER-YGWIVVRVIAEDRPDEIIRRVHDARRRRS-------
Mflv_4708|M.gilvum_PYR-GCK FNKGIRRHDAVTE-LGWTDIRVTCNDTEGAIIARLTTAWRQRLCALGENP
MSMEG_5917|M.smegmatis_MC2_155 FNRDIHKSEDVRR-LGWTHIRVTAQDGEADILKRIEAAGVPR--------
TH_1775|M.thermoresistible__bu INRDIRRHDDMLE-MGWTVLRVTAADTDGGFLRRLETAWSRP-------A
MAB_1570|M.abscessus_ATCC_1997 YLKDIRRLEMLEG-MGWLIVRVVAEDHPHDIIRRVREALARRV-------
MMAR_5026|M.marinum_M YSWDIRRKEILER-LGWTVIRVLAGDRPTDILRRVRAALVRRASR-----
MUL_4737|M.ulcerans_Agy99 YAREQWRLRKLDE-LGWIVIRVIAGDAPEDVVRRVRQALARRGHRET---
Mvan_5526|M.vanbaalenii_PYR-1 YVKDIARLRMLEA-LGWIVIRVIAEDRPAHWLERTEAALQSRGCRLAATE
: : ** :** . * : * *
Mb1518c|M.bovis_AF2122/97 ------------------
Rv1482c|M.tuberculosis_H37Rv ------------------
MAV_3296|M.avium_104 ------------------
Mflv_4708|M.gilvum_PYR-GCK DAGPPWTHVRRQRPGQ--
MSMEG_5917|M.smegmatis_MC2_155 --GP---RV---------
TH_1775|M.thermoresistible__bu EHSPAQHSPAQRSPAQRS
MAB_1570|M.abscessus_ATCC_1997 ------------------
MMAR_5026|M.marinum_M ------------------
MUL_4737|M.ulcerans_Agy99 ------------------
Mvan_5526|M.vanbaalenii_PYR-1 LQLFVRTLAA--------