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VAVIRKFCHQLPGWIDQATRERAEADLANQGTRYRPEQLAALAGTLADCLNPDGLYRDEDRARRRSLTLD NQHADGMSELRGWLTPELRATLEAVLAKLAAPGMCNPLDENPCVDGTPTEQAIEGDTRSAAQRNHDGLLA GLRALLASGNLGQHNGLPASIIVTTTLADLETAAGRGLTGGGTLLPMSDVIRLSRHAHHYLAIFDHGKAL ALYHTKRLASPAQRIVLYAKDRGCTAPGCTIPGYYAEVHHCTDYATCHTTNINDLTFACGPHHRLLQPGA WTTHKNAKGETEWIPPPHLDRNQPRTNTFHHPEKLLQGEEDGDEDEDEP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2977 | - | - | 100% (329) | hypothetical protein MAV_2977 |
| M. avium 104 | MAV_2999 | - | 0.0 | 94.21% (328) | hypothetical protein MAV_2999 |
| M. avium 104 | MAV_1426 | - | 0.0 | 94.21% (328) | hypothetical protein MAV_1426 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1159c | - | 1e-137 | 71.21% (323) | hypothetical protein Mb1159c |
| M. gilvum PYR-GCK | Mflv_1835 | - | 6e-94 | 52.71% (332) | hypothetical protein Mflv_1835 |
| M. tuberculosis H37Rv | Rv1128c | - | 1e-136 | 70.90% (323) | hypothetical protein Rv1128c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0394c | - | 1e-103 | 57.37% (319) | hypothetical protein MAB_0394c |
| M. marinum M | MMAR_3121 | - | 1e-127 | 67.08% (325) | hypothetical protein MMAR_3121 |
| M. smegmatis MC2 155 | MSMEG_6573 | - | 3e-74 | 44.21% (337) | hypothetical protein MSMEG_6573 |
| M. thermoresistible (build 8) | TH_3287 | - | 1e-60 | 39.23% (362) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2371 | - | 1e-127 | 67.08% (325) | hypothetical protein MUL_2371 |
| M. vanbaalenii PYR-1 | Mvan_4827 | - | 2e-89 | 50.60% (332) | hypothetical protein Mvan_4827 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1159c|M.bovis_AF2122/97 -------MCSTREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCE
Rv1128c|M.tuberculosis_H37Rv -------MCSTREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCE
MAV_2977|M.avium_104 --------------------------------------------------
MMAR_3121|M.marinum_M ---MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRVLERLE
MUL_2371|M.ulcerans_Agy99 ---MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRVLERLE
MAB_0394c|M.abscessus_ATCC_199 -----------MSPIDDLLTTATAVVESS----FDELNNPELLSALRQLE
TH_3287|M.thermoresistible__bu MGQQFVTAGAARARVGELLAAVDAAYAEMRALCLDEVGTGFRLELAERLE
Mflv_1835|M.gilvum_PYR-GCK ----MYVRVMSGGDLQTRIAVLRAAFDEVAACEIELLTRPDLVAALDELE
Mvan_4827|M.vanbaalenii_PYR-1 ----MYVRAMSGSDVQAAVTALRTAFDDMAACDVDLLTRPDLVAALDELE
MSMEG_6573|M.smegmatis_MC2_155 ---------MDDG-VQDAVAALDAALNTLLTLPHSALTDAELLTICAGLQ
Mb1159c|M.bovis_AF2122/97 TARRQLPSVEHTLINQIGEQSTEEELGGKLGLTLADR-LRITRSEAKRRV
Rv1128c|M.tuberculosis_H37Rv TARRQLPSVEHTLINQIGEQSTEEELGGKLGLTLADR-LRITRSEAKRRV
MAV_2977|M.avium_104 --------------------------------------------------
MMAR_3121|M.marinum_M VVARRLPVAQYALLNQLDEQAGEAELGGRLAAVVASR-LRITRSEAGRRV
MUL_2371|M.ulcerans_Agy99 VVARRLPAAQYALVNQLDEQPGEAELGGRLAAVVASR-LRITRSEAGRRV
MAB_0394c|M.abscessus_ATCC_199 IAQRKITAASHTLTARLVQRGSPVALGGTSFAEVLARYLSITTATARRRL
TH_3287|M.thermoresistible__bu TQCRINRGLMYRVFAQLADPPDEPAMVPAVRDRLWAR-LRITPGEVKRRL
Mflv_1835|M.gilvum_PYR-GCK ELSCQLPAVGHRLLARLQAEGTPQQMGAKNWSEVLRVRWRISGSEAHRRL
Mvan_4827|M.vanbaalenii_PYR-1 TVGCRLPALSYRLLARLQAETTPPQMGAKSWKEVLAVRWRISTSEAHRRL
MSMEG_6573|M.smegmatis_MC2_155 DARNRIPAVEHRAIAALSQQTTPAAIGAKSWPLVLATRLGISSKEARRRC
Mb1159c|M.bovis_AF2122/97 AEAADLGQRRALTGEPLPPLLTATAKAQRHGLIGDGHVEVIRAFVHRLPS
Rv1128c|M.tuberculosis_H37Rv AEAADLGQRRALTGEPLPPLLTATAKAQRHGLIGDGHVEVIRAFVHRLPS
MAV_2977|M.avium_104 -------------------------------------MAVIRKFCHQLPG
MMAR_3121|M.marinum_M AEAADVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFFRRLPA
MUL_2371|M.ulcerans_Agy99 AEAAEVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFFRQLPA
MAB_0394c|M.abscessus_ATCC_199 ADAAHLGPRRALTGEPLRPALPYVAHALREGRLGDEHVRIIRRFFDVLPD
TH_3287|M.thermoresistible__bu RVAALLRPRRRLSGPPLPPVLARVAGAVESGLLGEEHLRVITTVMAALPS
Mflv_1835|M.gilvum_PYR-GCK TEAALLAPRPSLTGPALPPQLAATAIAQARGLINAEHVAVIRKAVKKLPG
Mvan_4827|M.vanbaalenii_PYR-1 TEAAVLAPRQAMTGEALPPVLPATAAAQAHGLINAEHVEVIRKAMAKLPG
MSMEG_6573|M.smegmatis_MC2_155 TDAAELGPRVSMTGEALAPKREHIAAAQADGTLTPDHVAELFKFFTKCPD
: : *
Mb1159c|M.bovis_AF2122/97 WVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLNPDG-DYTDEDRA
Rv1128c|M.tuberculosis_H37Rv WVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLNPDG-DYTDEDRA
MAV_2977|M.avium_104 WIDQATRERAEADLANQGTRYRPEQLAALAGTLADCLNPDG-LYRDEDRA
MMAR_3121|M.marinum_M GVDVGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPDG-RHSDEDRA
MUL_2371|M.ulcerans_Agy99 GVDVGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPDG-RHSDEDRA
MAB_0394c|M.abscessus_ATCC_199 AVDADTREAAEKQLASMGTEFGPEQLRAGADRIAALVNPDG-RFSDIDRA
TH_3287|M.thermoresistible__bu AVSVTDREAVEASLIAEAARSDAGIVRQVGRRIEEIFNPDG-HYDDQDRA
Mflv_1835|M.gilvum_PYR-GCK WVDVATREQFEVNLVRTAVGHGPKELNDAADRMLFLLDQDGPEPDDAERG
Mvan_4827|M.vanbaalenii_PYR-1 FVDTATRERIEVDLVRTAVGNGPKELKDSADRTLFLLDQDGPEPDERERA
MSMEG_6573|M.smegmatis_MC2_155 WVTYAEQCRLEEKLVTGAIGADPETVRQAVDHAVFLLDQDGPAPTDNPPT
: * * . . : .: ** :
Mb1159c|M.bovis_AF2122/97 RRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAPGMCNPEQ---
Rv1128c|M.tuberculosis_H37Rv RRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAPGMCNPEQ---
MAV_2977|M.avium_104 RRRSLTLDNQHADGMSELRGWLTPELRATLEAVLAKLAAPGMCNPLD---
MMAR_3121|M.marinum_M RRRGLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAPGMCNPED---
MUL_2371|M.ulcerans_Agy99 RRRGLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAPGMCNPED---
MAB_0394c|M.abscessus_ATCC_199 RRRGISIGRQGADGMSALSGLLDPETRAYFDAVLSKLAAPGMCDPRD---
TH_3287|M.thermoresistible__bu RRRGIHLGDQQRDGMSAISGWIDPQLRAYLEAVTAAVR-PGRHLPHTTTD
Mflv_1835|M.gilvum_PYR-GCK RKRGVSIGRQGAEAMSALTGQLTPEARAVWEAIFAKYAAPGMCNPDD---
Mvan_4827|M.vanbaalenii_PYR-1 RKRAVTKHKQREDGMVDVSATLTPEAWAVWEAIFAKFAAPGMCNPDD---
MSMEG_6573|M.smegmatis_MC2_155 KPFGITFGPQQPDGSYHLRGKVSAEFKATFDPIDEKLAAPGMCNPTD---
: .: * :. : . : .: * :.: ** *
Mb1159c|M.bovis_AF2122/97 --------KAPCVNGAPSKEQARRDT---------------RSCPQRNHD
Rv1128c|M.tuberculosis_H37Rv --------KAPCVNGAPSKEQARRDT---------------RSCPQRNHD
MAV_2977|M.avium_104 --------ENPCVDGTPTEQAIEGDT---------------RSAAQRNHD
MMAR_3121|M.marinum_M --------EAAVVDGPVSPDAADRDS---------------RSVGQRQHD
MUL_2371|M.ulcerans_Agy99 --------EAAVVDGPVSRDAADRDS---------------RSVSQRQHD
MAB_0394c|M.abscessus_ATCC_199 --------ESPMTEGEPDSAAAERDT---------------RTSAQRNHD
TH_3287|M.thermoresistible__bu TTGTTGTTETTGTAGTAGTAATAADTAADGVGDIDTGGVDLRSAAQRRHD
Mflv_1835|M.gilvum_PYR-GCK --------EQPCTSGTPSQAQIDGDH---------------RSLAQRQHD
Mvan_4827|M.vanbaalenii_PYR-1 --------PEPCTSGTPSQAQIDNDH---------------RSLAQRQHD
MSMEG_6573|M.smegmatis_MC2_155 --------QTPCISGTPSQQQIDSDQ---------------RGAPERRHD
. * * * :*.**
Mb1159c|M.bovis_AF2122/97 ALNAGLRSLLTSGNLGQHNGLPASIIVTTTLKDLEAAA-----------G
Rv1128c|M.tuberculosis_H37Rv ALNAELRSLLTSGNLGQHNGLPASIIVTTTLKDLEAAA-----------G
MAV_2977|M.avium_104 GLLAGLRALLASGNLGQHNGLPASIIVTTTLADLETAA-----------G
MMAR_3121|M.marinum_M GFNAALRAVLASGELGQHNGLPASIIVSTTLKELEAAA-----------G
MUL_2371|M.ulcerans_Agy99 GFNAALRAVLASGELGQHNGLPASIIVSTTLKELEAAA-----------G
MAB_0394c|M.abscessus_ATCC_199 GLRACLRSTLASGKLGAHRGLPVTVVVSTTLRELQSAA-----------G
TH_3287|M.thermoresistible__bu GLTLGLKIAVASGRLGSHRGHPVTVIVRTTLGELNQAAHAVADPRVSMPG
Mflv_1835|M.gilvum_PYR-GCK ALLAVGRIALMSGELGQLNGLPVSVIIRTTLQDLESRA-----------G
Mvan_4827|M.vanbaalenii_PYR-1 ALLAGGRIALMSGQLGQLNGLPVSVIIRTTLQDLESRA-----------G
MSMEG_6573|M.smegmatis_MC2_155 AMLTAMRLLLAHKDLGQINGLPATLLVTTTLQELEKAA-----------G
.: : : ** .* *.:::: *** :*: * *
Mb1159c|M.bovis_AF2122/97 AGLTGGGTILPISDVIRLARHANHYLAIFDRG--KALALYHTKRLASPAQ
Rv1128c|M.tuberculosis_H37Rv AGLTGGGTILPISDVIRLARHANHYLAIFDRG--KALALYHTKRLASPAQ
MAV_2977|M.avium_104 RGLTGGGTLLPMSDVIRLSRHAHHYLAIFDHG--KALALYHTKRLASPAQ
MMAR_3121|M.marinum_M RGLTGGGTLLPMSDVIRLARHAHHYLAVFDRG--EAIGLYHAKRLATPGQ
MUL_2371|M.ulcerans_Agy99 RGLTGGGTLLPMSDVIRLARHAHHYLAVFDRG--EAIGLYHAKRLATPGQ
MAB_0394c|M.abscessus_ATCC_199 RAISGSGNLVPIPDLIRMATHAFHYLTIFGDD-GRPLHLGRSKRIATPDQ
TH_3287|M.thermoresistible__bu PARTGGTGVLPMRELIRMAADAIHYLAVFDDHTERPLYLGRQKRIATADQ
Mflv_1835|M.gilvum_PYR-GCK IGVSGGGTKLPIRDVIRMAGHANHYLAVFDRATGSALDLFRTRRVASPAQ
Mvan_4827|M.vanbaalenii_PYR-1 VGVTGGGTVMPIAEVIRMAGHAHHYLAVFDRATGSALDLFRTRRIASPAQ
MSMEG_6573|M.smegmatis_MC2_155 VAITAGGTKLSIPDLIRLASQALHYLAVYDEHTGIPLYLGRARRTASAGQ
. :.. :.: ::**:: .* ***:::. .: * : :* *:. *
Mb1159c|M.bovis_AF2122/97 RIMLYAKDSGCSAPGCDVPGYYCEVHHVT-PYAQCRNTDVNDLTLGCGGH
Rv1128c|M.tuberculosis_H37Rv RIMLYAKDSGCSAPGCDVPGYYCEVHHVT-PYAQCRNTDVNDLTLGCGGH
MAV_2977|M.avium_104 RIVLYAKDRGCTAPGCTIPGYYAEVHHCT-DYATCHTTNINDLTFACGPH
MMAR_3121|M.marinum_M RIVLYAKDRGCTRPGCDVAGYQCEVHHVA-AWAISGRTDINQLTLACGPD
MUL_2371|M.ulcerans_Agy99 RIVLYAKDRGCTRPGCDVAGYQCEVHHVA-AWAISGRTDINQLTLACGPD
MAB_0394c|M.abscessus_ATCC_199 RIVLHAKDRGCSAPGCTVPGYLCQVHHVD-DWRDDGPTDIDNLTFACGPH
TH_3287|M.thermoresistible__bu RLICYARDGGCTAPGCGEPGYHAETHHQP-AWEDGGLTDADHLFFACGPH
Mflv_1835|M.gilvum_PYR-GCK RVMLIARDGGCTKPCCTVGAYGCQVHHAEADYAHGGNTNIDELGLACGPD
Mvan_4827|M.vanbaalenii_PYR-1 RIMLIARDGGCTKPGCPVGAYGCQGHHVEADFAQGGNTNVDELGLACGPD
MSMEG_6573|M.smegmatis_MC2_155 RLAIWARDRGCTRPGCTANGYRCQAHHATTDYAKGGLTDADALALACGCD
*: *:* **: * * .* .: ** : *: : * :.** .
Mb1159c|M.bovis_AF2122/97 HP--LAERG-WTTRKNAHGDTEWLPPPHLDHGQPRVNTFHHPEKLLAD--
Rv1128c|M.tuberculosis_H37Rv HP--LAERG-WTTRKNAHGDTEWLPPPHLDHGQPRVNTFHHPEKLLAD--
MAV_2977|M.avium_104 HR--LLQPGAWTTHKNAKGETEWIPPPHLDRNQPRTNTFHHPEKLLQGEE
MMAR_3121|M.marinum_M HK--LLEQG-WRTRKNAHGDTEWLPPPHLDHGQPRTNTYHHPEKLLRDSA
MUL_2371|M.ulcerans_Agy99 HK--LLEQG-WRTRKNAHGDTEWLPPPHLDHGQPRTNSYHHPEKLLRDSA
MAB_0394c|M.abscessus_ATCC_199 HR--LLQQGWTTRKRRSDGITEWIPPPHLDTGQSRTNDHHHPERFIRRF-
TH_3287|M.thermoresistible__bu HS--GLTEGRWQATITPTGRLAWTNDHHPPT----VNHAHHPEELLRAHT
Mflv_1835|M.gilvum_PYR-GCK NRSVTD--GGWTTRMNDRCEVEWIPPPGLDTGQARVNTYHRPERLLRP--
Mvan_4827|M.vanbaalenii_PYR-1 NRDVNDH-GGWTTQMNERCEVEWTPPPPLDTGQARINNYHRPERLLRPP-
MSMEG_6573|M.smegmatis_MC2_155 NRLVGEAPNKWTTRINNHGQCEWIPPDLLDRGQHRTNTYHHPETLLADIN
: . * * *:** ::
Mb1159c|M.bovis_AF2122/97 ----DEGDP-----------------------------------------
Rv1128c|M.tuberculosis_H37Rv ----DEGDP-----------------------------------------
MAV_2977|M.avium_104 DGDEDEDEP-----------------------------------------
MMAR_3121|M.marinum_M D-DDDEGHGAA---------------------------------------
MUL_2371|M.ulcerans_Agy99 D-DDDEGHGAA---------------------------------------
MAB_0394c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3287|M.thermoresistible__bu DPPEDPG-------------------------------------------
Mflv_1835|M.gilvum_PYR-GCK EDPEPLGDN----------------------------------DSQ--AS
Mvan_4827|M.vanbaalenii_PYR-1 EEPEPHSDNDI-------------------AATAKPAEGNEIGDAQPGAP
MSMEG_6573|M.smegmatis_MC2_155 RDQKTDGDNREQHHTDTGADTGTVHVNGHGEKPAIPPELLDQGQQRTAPY
Mb1159c|M.bovis_AF2122/97 --------------------------------------------------
Rv1128c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2977|M.avium_104 --------------------------------------------------
MMAR_3121|M.marinum_M --------------------------------------------------
MUL_2371|M.ulcerans_Agy99 --------------------------------------------------
MAB_0394c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3287|M.thermoresistible__bu --------------------------------------------------
Mflv_1835|M.gilvum_PYR-GCK RPADDP----------------------GEPGGP----APPEGEAA----
Mvan_4827|M.vanbaalenii_PYR-1 HPADNP----------------------GEPGGP----APPDNQAA----
MSMEG_6573|M.smegmatis_MC2_155 HQAEVPPVNTRDTRSSTTTRDANRHNGNGDRNSAENRNGPSKNAAGDDDE
Mb1159c|M.bovis_AF2122/97 --
Rv1128c|M.tuberculosis_H37Rv --
MAV_2977|M.avium_104 --
MMAR_3121|M.marinum_M --
MUL_2371|M.ulcerans_Agy99 --
MAB_0394c|M.abscessus_ATCC_199 --
TH_3287|M.thermoresistible__bu --
Mflv_1835|M.gilvum_PYR-GCK --
Mvan_4827|M.vanbaalenii_PYR-1 --
MSMEG_6573|M.smegmatis_MC2_155 PR