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MYVRAMSGSDVQAAVTALRTAFDDMAACDVDLLTRPDLVAALDELETVGCRLPALSYRLLARLQAETTPP QMGAKSWKEVLAVRWRISTSEAHRRLTEAAVLAPRQAMTGEALPPVLPATAAAQAHGLINAEHVEVIRKA MAKLPGFVDTATRERIEVDLVRTAVGNGPKELKDSADRTLFLLDQDGPEPDERERARKRAVTKHKQREDG MVDVSATLTPEAWAVWEAIFAKFAAPGMCNPDDPEPCTSGTPSQAQIDNDHRSLAQRQHDALLAGGRIAL MSGQLGQLNGLPVSVIIRTTLQDLESRAGVGVTGGGTVMPIAEVIRMAGHAHHYLAVFDRATGSALDLFR TRRIASPAQRIMLIARDGGCTKPGCPVGAYGCQGHHVEADFAQGGNTNVDELGLACGPDNRDVNDHGGWT TQMNERCEVEWTPPPPLDTGQARINNYHRPERLLRPPEEPEPHSDNDIAATAKPAEGNEIGDAQPGAPHP ADNPGEPGGPAPPDNQAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4827 | - | - | 100% (508) | hypothetical protein Mvan_4827 |
| M. vanbaalenii PYR-1 | Mvan_4912 | - | 0.0 | 94.49% (508) | hypothetical protein Mvan_4912 |
| M. vanbaalenii PYR-1 | Mvan_3231 | - | 0.0 | 90.02% (511) | hypothetical protein Mvan_3231 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1159c | - | 1e-113 | 49.00% (449) | hypothetical protein Mb1159c |
| M. gilvum PYR-GCK | Mflv_4397 | - | 0.0 | 76.54% (503) | hypothetical protein Mflv_4397 |
| M. tuberculosis H37Rv | Rv1128c | - | 1e-112 | 48.78% (449) | hypothetical protein Rv1128c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0394c | - | 4e-96 | 45.31% (426) | hypothetical protein MAB_0394c |
| M. marinum M | MMAR_3121 | - | 1e-108 | 46.97% (445) | hypothetical protein MMAR_3121 |
| M. avium 104 | MAV_2999 | - | 1e-112 | 47.48% (457) | hypothetical protein MAV_2999 |
| M. smegmatis MC2 155 | MSMEG_6573 | - | 1e-109 | 46.29% (445) | hypothetical protein MSMEG_6573 |
| M. thermoresistible (build 8) | TH_3287 | - | 6e-63 | 35.86% (488) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2371 | - | 1e-108 | 46.97% (445) | hypothetical protein MUL_2371 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_0394c|M.abscessus_ATCC_199 -----------MSPIDDLLTTATAVVESS----FDELNNPELLSALRQLE
TH_3287|M.thermoresistible__bu MGQQFVTAGAARARVGELLAAVDAAYAEMRALCLDEVGTGFRLELAERLE
Mb1159c|M.bovis_AF2122/97 -------MCSTREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCE
Rv1128c|M.tuberculosis_H37Rv -------MCSTREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCE
MAV_2999|M.avium_104 ----MRGMSSDREAVSAAFDAIDAALDDLLDCDYAALATREKLALLNRCE
MMAR_3121|M.marinum_M ---MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRVLERLE
MUL_2371|M.ulcerans_Agy99 ---MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRVLERLE
Mvan_4827|M.vanbaalenii_PYR-1 ----MYVRAMSGSDVQAAVTALRTAFDDMAACDVDLLTRPDLVAALDELE
Mflv_4397|M.gilvum_PYR-GCK ---------MSGGDLQTSIAALRAAFEEVAAADVDLLTRPDLVAALDELE
MSMEG_6573|M.smegmatis_MC2_155 ---------MDDG-VQDAVAALDAALNTLLTLPHSALTDAELLTICAGLQ
: . . : : :
MAB_0394c|M.abscessus_ATCC_199 IAQRKITAASHTLTARLVQRGSPVALGGTSFAEVLARYLSITTATARRRL
TH_3287|M.thermoresistible__bu TQCRINRGLMYRVFAQLADPPDEPAMVPAVRDRLWAR-LRITPGEVKRRL
Mb1159c|M.bovis_AF2122/97 TARRQLPSVEHTLINQIGEQSTEEELGGKLGLTLADR-LRITRSEAKRRV
Rv1128c|M.tuberculosis_H37Rv TARRQLPSVEHTLINQIGEQSTEEELGGKLGLTLADR-LRITRSEAKRRV
MAV_2999|M.avium_104 RLRRRLPAIEHPLINALARDATPAELGGRLSHAIAEA-TLISRAEAARRV
MMAR_3121|M.marinum_M VVARRLPVAQYALLNQLDEQAGEAELGGRLAAVVASR-LRITRSEAGRRV
MUL_2371|M.ulcerans_Agy99 VVARRLPAAQYALVNQLDEQPGEAELGGRLAAVVASR-LRITRSEAGRRV
Mvan_4827|M.vanbaalenii_PYR-1 TVGCRLPALSYRLLARLQAETTPPQMGAKSWKEVLAVRWRISTSEAHRRL
Mflv_4397|M.gilvum_PYR-GCK ELSCQLPAVGHRLLARLQVETSAREMGAKSWNQVLAVRWRISTGEAHRRL
MSMEG_6573|M.smegmatis_MC2_155 DARNRIPAVEHRAIAALSQQTTPAAIGAKSWPLVLATRLGISSKEARRRC
: : : : *: . **
MAB_0394c|M.abscessus_ATCC_199 ADAAHLGPRRALTGEPLRPALPYVAHALREGRLGDEHVRIIRRFFDVLPD
TH_3287|M.thermoresistible__bu RVAALLRPRRRLSGPPLPPVLARVAGAVESGLLGEEHLRVITTVMAALPS
Mb1159c|M.bovis_AF2122/97 AEAADLGQRRALTGEPLPPLLTATAKAQRHGLIGDGHVEVIRAFVHRLPS
Rv1128c|M.tuberculosis_H37Rv AEAADLGQRRALTGEPLPPLLTATAKAQRHGLIGDGHVEVIRAFVHRLPS
MAV_2999|M.avium_104 HTAADLGPRVGLTGEPLPPLLAATAAAQREGSLGLEQVAVIRKFCHQLPG
MMAR_3121|M.marinum_M AEAADVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFFRRLPA
MUL_2371|M.ulcerans_Agy99 AEAAEVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFFRQLPA
Mvan_4827|M.vanbaalenii_PYR-1 TEAAVLAPRQAMTGEALPPVLPATAAAQAHGLINAEHVEVIRKAMAKLPG
Mflv_4397|M.gilvum_PYR-GCK TEAALLAPRQSLTGTPLPPALPATAVAQSRGLINAEHVEVIRKAVKKLPG
MSMEG_6573|M.smegmatis_MC2_155 TDAAELGPRVSMTGEALAPKREHIAAAQADGTLTPDHVAELFKFFTKCPD
** : * ::* .: * * * * : :: : *
MAB_0394c|M.abscessus_ATCC_199 AVDADTREAAEKQLASMGTEFGPEQLRAGADRIAALVNPDG-RFSDIDRA
TH_3287|M.thermoresistible__bu AVSVTDREAVEASLIAEAARSDAGIVRQVGRRIEEIFNPDG-HYDDQDRA
Mb1159c|M.bovis_AF2122/97 WVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLNPDG-DYTDEDRA
Rv1128c|M.tuberculosis_H37Rv WVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLNPDG-DYTDEDRA
MAV_2999|M.avium_104 WIDQATRERAEADLANQGTRYRPEQLAALAGTLADCLNPDG-LYRDEDRA
MMAR_3121|M.marinum_M GVDVGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPDG-RHSDEDRA
MUL_2371|M.ulcerans_Agy99 GVDVGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPDG-RHSDEDRA
Mvan_4827|M.vanbaalenii_PYR-1 FVDTATRERIEVDLVRTAVGNGPKELKDSADRTLFLLDQDGPEPDERERA
Mflv_4397|M.gilvum_PYR-GCK WVDVATREQFEVNLVRTAVGNGPKELRDAAELTLFLLDQDGPEPDDTERA
MSMEG_6573|M.smegmatis_MC2_155 WVTYAEQCRLEEKLVTGAIGADPETVRQAVDHAVFLLDQDGPAPTDNPPT
: * * . . : .: ** : :
MAB_0394c|M.abscessus_ATCC_199 RRRGISIGRQGADGMSALSGLLDPETRAYFDAVLSKLAAPGMCDPRD---
TH_3287|M.thermoresistible__bu RRRGIHLGDQQRDGMSAISGWIDPQLRAYLEAVTAAVR-PGRHLPHTTTD
Mb1159c|M.bovis_AF2122/97 RRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAPGMCNPEQ---
Rv1128c|M.tuberculosis_H37Rv RRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAPGMCNPEQ---
MAV_2999|M.avium_104 RRRSLTLGNQHADGMSELRGLLTPELRATLEAVLAKLAAPGMCNPLD---
MMAR_3121|M.marinum_M RRRGLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAPGMCNPED---
MUL_2371|M.ulcerans_Agy99 RRRGLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAPGMCNPED---
Mvan_4827|M.vanbaalenii_PYR-1 RKRAVTKHKQREDGMVDVSATLTPEAWAVWEAIFAKFAAPGMCNPDD---
Mflv_4397|M.gilvum_PYR-GCK RKRGLTKGKQRPDGMIDLAGTLTPEAWAVLEVIFAKYAAPGMCNPAD---
MSMEG_6573|M.smegmatis_MC2_155 KPFGITFGPQQPDGSYHLRGKVSAEFKATFDPIDEKLAAPGMCNPTD---
: .: * ** : . : .: * : : ** *
MAB_0394c|M.abscessus_ATCC_199 --------ESPMTEGEPDSAAAERDT---------------RTSAQRNHD
TH_3287|M.thermoresistible__bu TTGTTGTTETTGTAGTAGTAATAADTAADGVGDIDTGGVDLRSAAQRRHD
Mb1159c|M.bovis_AF2122/97 --------KAPCVNGAPSKEQARRDT---------------RSCPQRNHD
Rv1128c|M.tuberculosis_H37Rv --------KAPCVNGAPSKEQARRDT---------------RSCPQRNHD
MAV_2999|M.avium_104 --------ESPCVDGTPTEQAIEGDT---------------RSAAQRNHD
MMAR_3121|M.marinum_M --------EAAVVDGPVSPDAADRDS---------------RSVGQRQHD
MUL_2371|M.ulcerans_Agy99 --------EAAVVDGPVSRDAADRDS---------------RSVSQRQHD
Mvan_4827|M.vanbaalenii_PYR-1 --------PEPCTSGTPSQAQIDNDH---------------RSLAQRQHD
Mflv_4397|M.gilvum_PYR-GCK --------PEPCTYGTPTQAQIDNDQ---------------RSLAQRQHD
MSMEG_6573|M.smegmatis_MC2_155 --------QTPCISGTPSQQQIDSDQ---------------RGAPERRHD
. * * * :*.**
MAB_0394c|M.abscessus_ATCC_199 GLRACLRSTLASGKLGAHRGLPVTVVVSTTLRELQSAA-----------G
TH_3287|M.thermoresistible__bu GLTLGLKIAVASGRLGSHRGHPVTVIVRTTLGELNQAAHAVADPRVSMPG
Mb1159c|M.bovis_AF2122/97 ALNAGLRSLLTSGNLGQHNGLPASIIVTTTLKDLEAAA-----------G
Rv1128c|M.tuberculosis_H37Rv ALNAELRSLLTSGNLGQHNGLPASIIVTTTLKDLEAAA-----------G
MAV_2999|M.avium_104 GLLAGLRALLASGNLGQHNGLPASIIVTTTLADLETAA-----------G
MMAR_3121|M.marinum_M GFNAALRAVLASGELGQHNGLPASIIVSTTLKELEAAA-----------G
MUL_2371|M.ulcerans_Agy99 GFNAALRAVLASGELGQHNGLPASIIVSTTLKELEAAA-----------G
Mvan_4827|M.vanbaalenii_PYR-1 ALLAGGRIALMSGQLGQLNGLPVSVIIRTTLQDLESRA-----------G
Mflv_4397|M.gilvum_PYR-GCK ALVAVGRIALMSGELGQLNGLPVSIIIRTTLQDLESRA-----------G
MSMEG_6573|M.smegmatis_MC2_155 AMLTAMRLLLAHKDLGQINGLPATLLVTTTLQELEKAA-----------G
.: : : ** .* *.:::: *** :*: * *
MAB_0394c|M.abscessus_ATCC_199 RAISGSGNLVPIPDLIRMATHAFHYLTIFGDD-GRPLHLGRSKRIATPDQ
TH_3287|M.thermoresistible__bu PARTGGTGVLPMRELIRMAADAIHYLAVFDDHTERPLYLGRQKRIATADQ
Mb1159c|M.bovis_AF2122/97 AGLTGGGTILPISDVIRLARHANHYLAIFDRG--KALALYHTKRLASPAQ
Rv1128c|M.tuberculosis_H37Rv AGLTGGGTILPISDVIRLARHANHYLAIFDRG--KALALYHTKRLASPAQ
MAV_2999|M.avium_104 KGLTGGGTLLPMSDVIRLSRHAHHYLAIFDKG--KALALYHTKRLASPGQ
MMAR_3121|M.marinum_M RGLTGGGTLLPMSDVIRLARHAHHYLAVFDRG--EAIGLYHAKRLATPGQ
MUL_2371|M.ulcerans_Agy99 RGLTGGGTLLPMSDVIRLARHAHHYLAVFDRG--EAIGLYHAKRLATPGQ
Mvan_4827|M.vanbaalenii_PYR-1 VGVTGGGTVMPIAEVIRMAGHAHHYLAVFDRATGSALDLFRTRRIASPAQ
Mflv_4397|M.gilvum_PYR-GCK VGTTGGGTVVPIKDVIRMAGHANHYLAVFDRATGSALDLFRTRRVASPAQ
MSMEG_6573|M.smegmatis_MC2_155 VAITAGGTKLSIPDLIRLASQALHYLAVYDEHTGIPLYLGRARRTASAGQ
. :.. :.: ::**:: .* ***:::. .: * : :* *:. *
MAB_0394c|M.abscessus_ATCC_199 RIVLHAKDRGCSAPGCTVPGYLCQVHHVD-DWRDDGPTDIDNLTFACGPH
TH_3287|M.thermoresistible__bu RLICYARDGGCTAPGCGEPGYHAETHHQP-AWEDGGLTDADHLFFACGPH
Mb1159c|M.bovis_AF2122/97 RIMLYAKDSGCSAPGCDVPGYYCEVHHVT-PYAQCRNTDVNDLTLGCGGH
Rv1128c|M.tuberculosis_H37Rv RIMLYAKDSGCSAPGCDVPGYYCEVHHVT-PYAQCRNTDVNDLTLGCGGH
MAV_2999|M.avium_104 RIVLYAKDRGCTAPGCTVPGYYAEVHHCT-DYATCHTTDINDLTFACGPH
MMAR_3121|M.marinum_M RIVLYAKDRGCTRPGCDVAGYQCEVHHVA-AWAISGRTDINQLTLACGPD
MUL_2371|M.ulcerans_Agy99 RIVLYAKDRGCTRPGCDVAGYQCEVHHVA-AWAISGRTDINQLTLACGPD
Mvan_4827|M.vanbaalenii_PYR-1 RIMLIARDGGCTKPGCPVGAYGCQGHHVEADFAQGGNTNVDELGLACGPD
Mflv_4397|M.gilvum_PYR-GCK RVMLIARDGGCTKPCCTVGAYGCQVHHAETDYAHGGNTNIDELGLACGPD
MSMEG_6573|M.smegmatis_MC2_155 RLAIWARDRGCTRPGCTANGYRCQAHHATTDYAKGGLTDADALALACGCD
*: *:* **: * * .* .: ** : *: : * :.** .
MAB_0394c|M.abscessus_ATCC_199 HRLLQQGW--TTRKRRSDGITEWIPPPHLDTGQSRTNDHHHPERFIR---
TH_3287|M.thermoresistible__bu HSGLTEGR--WQATITPTGRLAWTNDHHPPT----VNHAHHPEELLR---
Mb1159c|M.bovis_AF2122/97 HPLAERG---WTTRKNAHGDTEWLPPPHLDHGQPRVNTFHHPEKLL----
Rv1128c|M.tuberculosis_H37Rv HPLAERG---WTTRKNAHGDTEWLPPPHLDHGQPRVNTFHHPEKLL----
MAV_2999|M.avium_104 HRLLQPGA--WTTHKNARGETQWLPPPHLDRNQPRTNTFHHPEKLLRG--
MMAR_3121|M.marinum_M HKLLEQG---WRTRKNAHGDTEWLPPPHLDHGQPRTNTYHHPEKLLR---
MUL_2371|M.ulcerans_Agy99 HKLLEQG---WRTRKNAHGDTEWLPPPHLDHGQPRTNSYHHPEKLLR---
Mvan_4827|M.vanbaalenii_PYR-1 NRDVNDHGG-WTTQMNERCEVEWTPPPPLDTGQARINNYHRPERLLR---
Mflv_4397|M.gilvum_PYR-GCK NRSVTEGG--WTTRINDRCEVEWIPPPGLDTGQARVNTYHRPERLLA---
MSMEG_6573|M.smegmatis_MC2_155 NRLVGEAPNKWTTRINNHGQCEWIPPDLLDRGQHRTNTYHHPETLLADIN
: * * *:** ::
MAB_0394c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3287|M.thermoresistible__bu --------------------------------------------------
Mb1159c|M.bovis_AF2122/97 --------------------------------------------------
Rv1128c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2999|M.avium_104 --------------------------------------------------
MMAR_3121|M.marinum_M --------------------------------------------------
MUL_2371|M.ulcerans_Agy99 --------------------------------------------------
Mvan_4827|M.vanbaalenii_PYR-1 --------------------------------PPEEPEPHSD-NDIAATA
Mflv_4397|M.gilvum_PYR-GCK --------------------------------PPDDPEPPNQ-TRTTAT-
MSMEG_6573|M.smegmatis_MC2_155 RDQKTDGDNREQHHTDTGADTGTVHVNGHGEKPAIPPELLDQGQQRTAPY
MAB_0394c|M.abscessus_ATCC_199 -----------------RF-------------------------------
TH_3287|M.thermoresistible__bu -----------------AHTDPPEDPG-----------------------
Mb1159c|M.bovis_AF2122/97 -----------------ADDEGDP--------------------------
Rv1128c|M.tuberculosis_H37Rv -----------------ADDEGDP--------------------------
MAV_2999|M.avium_104 -------------EDGGEDDDGDDDEAA----------------------
MMAR_3121|M.marinum_M ---------------DSADDDDEGHGAA----------------------
MUL_2371|M.ulcerans_Agy99 ---------------DSADDDDEGHGAA----------------------
Mvan_4827|M.vanbaalenii_PYR-1 KPAEGNEIGDAQPGAPHPADNPGEPGGP----------APPDNQAA----
Mflv_4397|M.gilvum_PYR-GCK EPVEDQAIDDPETDAPPPLDDPGEPGGP----------APPDNRAA----
MSMEG_6573|M.smegmatis_MC2_155 HQAEVPPVNTRDTRSSTTTRDANRHNGNGDRNSAENRNGPSKNAAGDDDE
MAB_0394c|M.abscessus_ATCC_199 --
TH_3287|M.thermoresistible__bu --
Mb1159c|M.bovis_AF2122/97 --
Rv1128c|M.tuberculosis_H37Rv --
MAV_2999|M.avium_104 --
MMAR_3121|M.marinum_M --
MUL_2371|M.ulcerans_Agy99 --
Mvan_4827|M.vanbaalenii_PYR-1 --
Mflv_4397|M.gilvum_PYR-GCK --
MSMEG_6573|M.smegmatis_MC2_155 PR