For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
RVVELASWTYVPSAGAALADWGADVIKVEGVSSGDPGRALVVSGFTREAARPDADFILELGNRGKRSIAI DIKSETGRELFGRLLASADVFLTNWLPGALERARLTVADIRAFNPRIIIARGTGLGVRGPDRDRGGFDAA TYLARGGVAYTLTPFGSETPAVQGPGFGDLQAGATLAGGVCAALFHRERTGEPTIVDSSLLAQAMWSIAP SISAADFFDIDGIPGAPPGLAINPLVNRYRTKDRRWIQLVFLQPDKYWAGFCRRIGLAELADDARFVPSS NLIANAAAATELLANTFARHDLSHWQTVLADEPGVWGALATPRETLNDPQVEPNGYVVTNVDDHGEKYRI VAAPVQFDETPPAPARAPEHGQHTEEILLELDVDWDDIAKAKALKAIL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2945 | - | - | 100% (399) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. avium 104 | MAV_1826 | - | 8e-91 | 42.86% (406) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. avium 104 | MAV_2565 | - | 2e-90 | 42.86% (406) | L-carnitine dehydratase/bile acid-inducible protein F |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1175 | mcr | 4e-30 | 29.62% (395) | alpha-methylacyl-CoA racemase |
| M. gilvum PYR-GCK | Mflv_2503 | - | 3e-82 | 40.45% (403) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv1143 | mcr | 4e-30 | 29.62% (395) | alpha-methylacyl-CoA racemase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4651c | - | 1e-29 | 28.53% (347) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_4713 | - | 2e-83 | 41.54% (402) | dehydratase |
| M. smegmatis MC2 155 | MSMEG_4798 | - | 4e-83 | 41.29% (402) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. thermoresistible (build 8) | TH_3557 | - | 4e-94 | 44.08% (397) | PUTATIVE putative L-carnitine dehydratase/bile acid-inducible |
| M. ulcerans Agy99 | MUL_3873 | - | 2e-63 | 39.09% (353) | dehydratase |
| M. vanbaalenii PYR-1 | Mvan_4155 | - | 3e-83 | 41.44% (403) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2503|M.gilvum_PYR-GCK MSKPLDGIRVLEVAMYGFVPSAGAVLAEWGADVIKVEHAVTGDPQRGLRQ
Mvan_4155|M.vanbaalenii_PYR-1 MSKPLDGIRVLEVAMYGFVPSAGAVLAEWGADVIKVEHAVTGDPQRGLRQ
MSMEG_4798|M.smegmatis_MC2_155 MSGPLEGIRILEVAMYGFVPSAGAVLGEWGADVIKVEHAVTGDPQRGLRQ
MMAR_4713|M.marinum_M -MKPLEGIRVLEVAMYGFVPSAGAVLAEWGADVIKVEHAVTGDPQRGLRQ
MUL_3873|M.ulcerans_Agy99 -----------------------MAFSTWGG--------IALDPER----
TH_3557|M.thermoresistible__bu ---------VLEVAAWTFVPSAGAVLAEWGAEVIKVEPVAGGDPQRGLVT
MAV_2945|M.avium_104 -------MRVVELASWTYVPSAGAALADWGADVIKVEGVSSGDPGRALVV
Mb1175|M.bovis_AF2122/97 MAGPLSGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPSSVDGISR---
Rv1143|M.tuberculosis_H37Rv MAGPLSGLRVVELAGIGPGPHAAMILGDLGADVVRIDRPSSVDGISR---
MAB_4651c|M.abscessus_ATCC_199 MTGALDGIRVLELGTLIAGPFAGRLLGDMGAEVLKIEPPGAPDPLRTWGQ
:. *. *
Mflv_2503|M.gilvum_PYR-GCK TGLLRVEG--DPNPNIEHANRLKRSIGLDMSVPEGKEVLLELARRADVFL
Mvan_4155|M.vanbaalenii_PYR-1 TGLLRVEG--DPNPNIEHANRLKRSIGLDMSVAEGREVLLELARRADVFL
MSMEG_4798|M.smegmatis_MC2_155 TGPLRVDG--DPNPNIEHANRGKRSIGLDMSVPAGREVLLELARRADVFL
MMAR_4713|M.marinum_M TGMLRVEG--DPNPNIEHANRGKRSLGLDMSISEGKEVLHELARRSDVFL
MUL_3873|M.ulcerans_Agy99 ------------HPLIEHPNRGKRSVGIDLATSDGQDVLHELARSADVFL
TH_3557|M.thermoresistible__bu MGIVDEGGG-VVNYMIEIPNRGKKSIGVDLLNPAGQEVVHELAKTCDVFL
MAV_2945|M.avium_104 SGFTREAARPDADFILELGNRGKRSIAIDIKSETGRELFGRLLASADVFL
Mb1175|M.bovis_AF2122/97 ----------------DAMLRNRRIVTADLKSDQGLELALKLIAKADVLI
Rv1143|M.tuberculosis_H37Rv ----------------DAMLRNRRIVTADLKSDQGLELALKLIAKADVLI
MAB_4651c|M.abscessus_ATCC_199 AEVDG------HHVFWTVHARNKKAITLDLRTEAGRALFLDLVDKSDVIV
* :: : *: * : * .**::
Mflv_2503|M.gilvum_PYR-GCK TSFLPGHRQKFGIDVDDIRAVNPKIIYARGSALGPRGEESVKGGYDMTAF
Mvan_4155|M.vanbaalenii_PYR-1 TSFLPGHRQKFGIDVDDIRAANPKIVYARGSALGPRGEESVKGGYDMTAF
MSMEG_4798|M.smegmatis_MC2_155 TSFLPGHREKFGIDVDDIRAVNPKIIYARGSALGPRGEESVKGGYDMTAF
MMAR_4713|M.marinum_M TSFLPGARRKFGIDLEDIRAVNPSIIYARGSALGPRGEEAAKGGYDMTAF
MUL_3873|M.ulcerans_Agy99 TNYLPSARQKNKFDVEHVRGANPDIIYARGTAYGDKGAERDVGGYDGTAF
TH_3557|M.thermoresistible__bu TSYLPGRRRRMRIDVEDIRAVNPNIVYVRGSGHGPDGPDADKPGYDGVSY
MAV_2945|M.avium_104 TNWLPGALERARLTVADIRAFNPRIIIARGTGLGVRGPDRDRGGFDAATY
Mb1175|M.bovis_AF2122/97 EGYRPGVTERLGLGPEECAKVNDRLIYARMTGWGQTGPRSQQAGHDIN-Y
Rv1143|M.tuberculosis_H37Rv EGYRPGVTERLGLGPEECAKVNDRLIYARMTGWGQTGPRSQQAGHDIN-Y
MAB_4651c|M.abscessus_ATCC_199 ENFRPGTLERWGLGYDVLAQRNKGIILVRVSGYGQTGPDAHKAGYASVAE
.: *. .: : * :: .* :. * * *.
Mflv_2503|M.gilvum_PYR-GCK WCRAGTAATITPPGTPGMVGPPGPAYGDTISG-TNLAGGIAAALLKRERS
Mvan_4155|M.vanbaalenii_PYR-1 WCRAGTAATITPPGTPGMVGPPGPAYGDTISG-TNLAGGIAAALLKRERT
MSMEG_4798|M.smegmatis_MC2_155 WCRAGAAATITPPGIEGMIGPPGPAYGDTISG-TNLAGGIAAALFKRERT
MMAR_4713|M.marinum_M WCRAGTAATITPMGYQGMINPPGPAYGDTISG-TNLAGGIAAALLKRERT
MUL_3873|M.ulcerans_Agy99 WTRSGVGHALTPPELGAPLAQGIPAFGDSIGG-MNIAGGISAALLHRERT
TH_3557|M.thermoresistible__bu WSRGGIAHVLT--EDAEELVRSRPAFGDLLGG-MTIAGGIAAALYKRATT
MAV_2945|M.avium_104 LARGGVAYTLTPFGSETPAVQG-PGFGDLQAG-ATLAGGVCAALFHRERT
Mb1175|M.bovis_AF2122/97 ISLNGILHAIG--RGDERPVPPLNLVGDFGGGSMFLLVGILAALWERQSS
Rv1143|M.tuberculosis_H37Rv ISLNGILHAIG--RGDERPVPPLNLVGDFGGGSMFLLVGILAALWERQSS
MAB_4651c|M.abscessus_ATCC_199 AAS-GLRHLNGFPGGPPP--RMALSIGDTLAG-MFAAQGALAALYRRTVT
* ** .* * *** .* :
Mflv_2503|M.gilvum_PYR-GCK GEPSVVDVSLLGSGLWALGHTVALTTHLGQRMEAFPPGVHGSPINPLVGL
Mvan_4155|M.vanbaalenii_PYR-1 GEPSIVDVSLLGSGLWALGHTVALTNHLHERMEAFPPGAHGSPINPLVGL
MSMEG_4798|M.smegmatis_MC2_155 GEPSVVDVSLLGSGLWAMGHTIALTSHLNELMVQPPPGVHGSPINPLVGL
MMAR_4713|M.marinum_M GEPSVVDVSLLGSGLWSLGHTVALTRHLGQRLEAPPPGIHGSPINPLVGV
MUL_3873|M.ulcerans_Agy99 GEALEVDVSLLSTAWWAAGASMTQGMDTGETMRSRMPQSGGMPMNPFMGN
TH_3557|M.thermoresistible__bu GEGSVVDVSLLGLAAWNLSPDIAVSQIHGG--SSIPTFGHADAPNPLVGN
MAV_2945|M.avium_104 GEPTIVDSSLLAQAMWSIAPSISAADFFDIDGIPGAP--PGLAINPLVNR
Mb1175|M.bovis_AF2122/97 GKGQVVDAAMVDGSSVLIQMMWAMRATGMWTDTRGANMLDGGAP--YYDT
Rv1143|M.tuberculosis_H37Rv GKGQVVDAAMVDGSSVLIQMMWAMRATGMWTDTRGANMLDGGAP--YYDT
MAB_4651c|M.abscessus_ATCC_199 GRGQVVDAALTESCLAVQESTIPDYDVGRVVRGPSGTRLEGIAP---SNI
*. ** :: . . . .
Mflv_2503|M.gilvum_PYR-GCK YATADDRYISFVMMQPTKFWADVCKHMDLDELADDPRFATAESIAEHTAL
Mvan_4155|M.vanbaalenii_PYR-1 YPTADDRYISFVMMQPTKFWADVCSHMDLDELVDDPRFATAESIAENTAD
MSMEG_4798|M.smegmatis_MC2_155 YGTADGRYISFVMMQPTKFWADVCRHMDLEHYIDDPRFATAESIAENTAA
MMAR_4713|M.marinum_M YATSDGRYISLVMMQPTKFWADVCRHIDRPDLAEDPRFATVEKIAAHTAD
MUL_3873|M.ulcerans_Agy99 YQTSDGGTINLCILSPTGYIRDTFEHLGIPEAADDPRFGEAEQLLRNADA
TH_3557|M.thermoresistible__bu YRTKDGRYVTLMMLQLDKFFAEAMHAIGLPQVLDDPRFADPAARFENRST
MAV_2945|M.avium_104 YRTKDRRWIQLVFLQPDKYWAGFCRRIGLAELADDARFVPSSNLIANAAA
Mb1175|M.bovis_AF2122/97 YECADGRYVAVGAIEP-QFYAAMLAGLGLDAAELPPQNDRAR-----WPE
Rv1143|M.tuberculosis_H37Rv YECADGRYVAVGAIEP-QFYAAMLAGLGLDAAELPPQNDRAR-----WPE
MAB_4651c|M.abscessus_ATCC_199 YQSADGSWVVIAANQDTVFRR-LCEAMGRPELSSDARFANHVARGRNQDD
* * : . . : :. .:
Mflv_2503|M.gilvum_PYR-GCK ANEILTEAMAKRPLTEWSERFATLAGPWAPVQDTLQAAEDAQIRANEYLV
Mvan_4155|M.vanbaalenii_PYR-1 AAEILKEAMSKRTLAEWSERFATLAGPWAPVQDTLQAAEDAQVRANEYLV
MSMEG_4798|M.smegmatis_MC2_155 AVDILTEAMKKRTLPEWSERFATLAGPWAPVQDTLQAAQDAQIRANEYLV
MMAR_4713|M.marinum_M AVEILTKAISARTLAEWSERFATLAGPWAPVQDTLQAADDAQVRANEYVV
MUL_3873|M.ulcerans_Agy99 AGALIARAVAARPFEYWRQRLKTMKGQWAPFQSLIELADDEQALANDMVA
TH_3557|M.thermoresistible__bu LIAMMDEVFAQRTLAEWREALAGLSGAWGVVQTPGEVCADPAVTANGYIA
MAV_2945|M.avium_104 ATELLANTFARHDLSHWQTVLADEPGVWGALATPRETLNDPQVEPNGYVV
Mb1175|M.bovis_AF2122/97 LRALLTEAFASHDRDHWGAVFANSDACVTPVLAFGEVHNEPHIIERNTFY
Rv1143|M.tuberculosis_H37Rv LRALLTEAFASHDRDHWGAVFANSDACVTPVLAFGEVHNEPHIIERNTFY
MAB_4651c|M.abscessus_ATCC_199 LDAIIAQWAAQRLPTDIIDVLSAAGVIAGPINTVADVVQDPQLKAREMLV
:: . : : . : : . .
Mflv_2503|M.gilvum_PYR-GCK QAG------ELELVSNPVQFDVAAP--VSGPAPGFAEQTDDILVELGLDW
Mvan_4155|M.vanbaalenii_PYR-1 QAG------ELELVANPVQFDVAAP--ASGPAPGFAEQTDDILVELGLDW
MSMEG_4798|M.smegmatis_MC2_155 QAG------ELELVTNPVQFDVSAP--SPGPAPGFAEQTDDILAELGLDW
MMAR_4713|M.marinum_M RAG------ELELVANPVQFDVAAP--QTGPAPGFAEQTDDILLELGFDW
MUL_3873|M.ulcerans_Agy99 EVDLGAGGPPFRVVRGPVQFNHEPL--TTTRAPQPGEHTETVLLELGMDW
TH_3557|M.thermoresistible__bu HTTTMNG-VPYAIPVNPVQFDRHHV--VPDGAPEHGQHTEEVLLDAGLGW
MAV_2945|M.avium_104 TNVDDHG-EKYRIVAAPVQFDETPP--APARAPEHGQHTEEILLELDVDW
Mb1175|M.bovis_AF2122/97 EAN------GGWQPMPAPRFSRTAS--SQPRPPAATIDIEAVLT----DW
Rv1143|M.tuberculosis_H37Rv EAN------GGWQPMPAPRFSRTAS--SQPRPPAATIDIEAVLT----DW
MAB_4651c|M.abscessus_ATCC_199 EHFDERLGRSVLGPGVVPVLSESPGGVRNAGPARPGQDNDDVYVGLLGKS
:. .. . : :
Mflv_2503|M.gilvum_PYR-GCK DRIIELKTAGAVT
Mvan_4155|M.vanbaalenii_PYR-1 DRIIELKTAGAVT
MSMEG_4798|M.smegmatis_MC2_155 DRIIELKTAGAVT
MMAR_4713|M.marinum_M DRIIELKTAGAVT
MUL_3873|M.ulcerans_Agy99 DRIDQLKRSGAIS
TH_3557|M.thermoresistible__bu DAIERYKQMGAVL
MAV_2945|M.avium_104 DDIAKAKALKAIL
Mb1175|M.bovis_AF2122/97 DG-----------
Rv1143|M.tuberculosis_H37Rv DG-----------
MAB_4651c|M.abscessus_ATCC_199 AQDIERLRAEGVL