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VSDILSGIRVVELAAWTFVPAAGAVLADWGADVIKIEHPETGDPQRGLISSGIVTGAGGVNHFIEQPNRG KRSIGLDTSTPDGLELLMKLLETADVFVTNLLPDSRQRMGIDVEQVRARNPKIIYARGHGYGTRGDLASQ GGFDLAAYWARGGIGDAYSAGDGTYPPIQRPAFGDSYGGLAIAGGIAAALVKRERTGEPSVVDVSLLNAA IWQLGPDIVGSGVTGQDIPKFNLDEMPNPVASIYKTRDNRFIAFVLLQADRFWADFCTRLGRTDLIEDER FANAVVRFGNRQECIGELRSAFESQDLSHWEKAFAGFDGVWDVMHTAHEVHSDPQVIANGYLPRVTDAND NEFALAASPVQFDEAPLDLTCAPGHGEHTDALLAELGFSEEEIIEFKINSVVL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2565 | - | - | 100% (403) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. avium 104 | MAV_1826 | - | 0.0 | 91.56% (403) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. avium 104 | MAV_2945 | - | 2e-90 | 42.86% (406) | L-carnitine dehydratase/bile acid-inducible protein F |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 3e-32 | 28.14% (398) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_2503 | - | 2e-89 | 45.48% (409) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv3272 | - | 2e-32 | 28.39% (398) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4651c | - | 3e-28 | 29.66% (408) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_4713 | - | 2e-92 | 45.66% (403) | dehydratase |
| M. smegmatis MC2 155 | MSMEG_4798 | - | 9e-89 | 44.53% (411) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. thermoresistible (build 8) | TH_3557 | - | 1e-100 | 47.47% (396) | PUTATIVE putative L-carnitine dehydratase/bile acid-inducible |
| M. ulcerans Agy99 | MUL_1046 | - | 1e-61 | 37.66% (385) | acyl-CoA transferase |
| M. vanbaalenii PYR-1 | Mvan_4155 | - | 1e-90 | 45.23% (409) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2503|M.gilvum_PYR-GCK -----MSKPLDGIRVLEVAMYGFVPSAGAVLAEWGADVIKVEHAVTGDPQ
Mvan_4155|M.vanbaalenii_PYR-1 -----MSKPLDGIRVLEVAMYGFVPSAGAVLAEWGADVIKVEHAVTGDPQ
MSMEG_4798|M.smegmatis_MC2_155 -----MSGPLEGIRILEVAMYGFVPSAGAVLGEWGADVIKVEHAVTGDPQ
MMAR_4713|M.marinum_M ------MKPLEGIRVLEVAMYGFVPSAGAVLAEWGADVIKVEHAVTGDPQ
TH_3557|M.thermoresistible__bu --------------VLEVAAWTFVPSAGAVLAEWGAEVIKVEPVAGGDPQ
MAV_2565|M.avium_104 -----MSDILSGIRVVELAAWTFVPAAGAVLADWGADVIKIEHPETGDPQ
MUL_1046|M.ulcerans_Agy99 -----MAGPVEGIKVVELGVWVAAPAAAAILADWGADVIKIEPPAG-DPG
Mb3300|M.bovis_AF2122/97 MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGG----
Rv3272|M.tuberculosis_H37Rv MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGG----
MAB_4651c|M.abscessus_ATCC_199 -----MTGALDGIRVLELGTLIAGPFAGRLLGDMGAEVLKIEPPGAPDP-
:::. * *. :* : **:*:*:*
Mflv_2503|M.gilvum_PYR-GCK RGLRQTGLLRVEG-DPNPNIEHANRLKRSIGLDMSVPEGKEVLLELARRA
Mvan_4155|M.vanbaalenii_PYR-1 RGLRQTGLLRVEG-DPNPNIEHANRLKRSIGLDMSVAEGREVLLELARRA
MSMEG_4798|M.smegmatis_MC2_155 RGLRQTGPLRVDG-DPNPNIEHANRGKRSIGLDMSVPAGREVLLELARRA
MMAR_4713|M.marinum_M RGLRQTGMLRVEG-DPNPNIEHANRGKRSLGLDMSISEGKEVLHELARRS
TH_3557|M.thermoresistible__bu RGLVTMGIVDEGGGVVNYMIEIPNRGKKSIGVDLLNPAGQEVVHELAKTC
MAV_2565|M.avium_104 RGLISSGIVTGAG-GVNHFIEQPNRGKRSIGLDTSTPDGLELLMKLLETA
MUL_1046|M.ulcerans_Agy99 R---LFGRMLGCDLGMNPPFEMDNRCKRSVVLDLSTDTGRELAYELLSDA
Mb3300|M.bovis_AF2122/97 EAARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTA
Rv3272|M.tuberculosis_H37Rv EAARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTA
MAB_4651c|M.abscessus_ATCC_199 --LRTWGQAEVDG--HHVFWTVHARNKKAITLDLRTEAGRALFLDLVDKS
* *::: :* . * .
Mflv_2503|M.gilvum_PYR-GCK DVFLTSFLPGHRQKFGIDVDDIRAVNPKIIYARGSALGPRGEESVKGGYD
Mvan_4155|M.vanbaalenii_PYR-1 DVFLTSFLPGHRQKFGIDVDDIRAANPKIVYARGSALGPRGEESVKGGYD
MSMEG_4798|M.smegmatis_MC2_155 DVFLTSFLPGHREKFGIDVDDIRAVNPKIIYARGSALGPRGEESVKGGYD
MMAR_4713|M.marinum_M DVFLTSFLPGARRKFGIDLEDIRAVNPSIIYARGSALGPRGEEAAKGGYD
TH_3557|M.thermoresistible__bu DVFLTSYLPGRRRRMRIDVEDIRAVNPNIVYVRGSGHGPDGPDADKPGYD
MAV_2565|M.avium_104 DVFVTNLLPDSRQRMGIDVEQVRARNPKIIYARGHGYGTRGDLASQGGFD
MUL_1046|M.ulcerans_Agy99 DVFITNVRPAALRGLGLDFAAVSDRNPRLVYGLITGYGETGPDADRAAYD
Mb3300|M.bovis_AF2122/97 DVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGID
Rv3272|M.tuberculosis_H37Rv DVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGID
MAB_4651c|M.abscessus_ATCC_199 DVIVENFRPGTLERWGLGYDVLAQRNKGIILVRVSGYGQTGPDAHKAGYA
**.: * . :. : * :: . * * . : .
Mflv_2503|M.gilvum_PYR-GCK MTAFWCRAGTAATITPPGTPGMVGPPGPAYGDTISGTNLAGGIAAALLKR
Mvan_4155|M.vanbaalenii_PYR-1 MTAFWCRAGTAATITPPGTPGMVGPPGPAYGDTISGTNLAGGIAAALLKR
MSMEG_4798|M.smegmatis_MC2_155 MTAFWCRAGAAATITPPGIEGMIGPPGPAYGDTISGTNLAGGIAAALFKR
MMAR_4713|M.marinum_M MTAFWCRAGTAATITPMGYQGMINPPGPAYGDTISGTNLAGGIAAALLKR
TH_3557|M.thermoresistible__bu GVSYWSRGGIAHVLT-EDAEELVRS-RPAFGDLLGGMTIAGGIAAALYKR
MAV_2565|M.avium_104 LAAYWARGGIGDAYS-AGDGTYPPIQRPAFGDSYGGLAIAGGIAAALVKR
MUL_1046|M.ulcerans_Agy99 VAAFWSRGGLAHLLTRPGDT--PPFQRGGMGDHTTGMTLAAAVCAAPLAR
Mb3300|M.bovis_AF2122/97 LVVAAEAGMTTGMPTPEGKPQIIPFQLVDN---ASGHVLAQAVLAALLHR
Rv3272|M.tuberculosis_H37Rv LVVAAEAGMTTGMPTPEGKPQIIPFQLVDN---ASGHVLAQAVLAALLHR
MAB_4651c|M.abscessus_ATCC_199 SVAEAASG-LRHLNGFPGGP--PPRMALSIGDTLAGMFAAQGALAALYRR
. . . * * . ** *
Mflv_2503|M.gilvum_PYR-GCK ERSGEPSVVDVSLLGSGLWALGHTVALTTHLGQRMEAFPPGVHGSPINPL
Mvan_4155|M.vanbaalenii_PYR-1 ERTGEPSIVDVSLLGSGLWALGHTVALTNHLHERMEAFPPGAHGSPINPL
MSMEG_4798|M.smegmatis_MC2_155 ERTGEPSVVDVSLLGSGLWAMGHTIALTSHLNELMVQPPPGVHGSPINPL
MMAR_4713|M.marinum_M ERTGEPSVVDVSLLGSGLWSLGHTVALTRHLGQRLEAPPPGIHGSPINPL
TH_3557|M.thermoresistible__bu ATTGEGSVVDVSLLGLAAWNLSPDIAVSQIHGG--SSIPTFGHADAPNPL
MAV_2565|M.avium_104 ERTGEPSVVDVSLLNAAIWQLGPDIVGSGVTGQ---DIPKFNLDEMPNPV
MUL_1046|M.ulcerans_Agy99 ERTGTGQLVSTSLYRQGAYTVSFDLNTYLLTGQ---QIAIGQRESMGNPC
Mb3300|M.bovis_AF2122/97 ERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKG
Rv3272|M.tuberculosis_H37Rv ERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKG
MAB_4651c|M.abscessus_ATCC_199 TVTGRGQVVDAALTESCLAVQESTIPDYDVGRVVRGPSGTRLEGIAPS--
.* .:*..:: :
Mflv_2503|M.gilvum_PYR-GCK VGLYATADDRY-----ISFVMMQPTKFWADVCKHMDLDELADDPRFATAE
Mvan_4155|M.vanbaalenii_PYR-1 VGLYPTADDRY-----ISFVMMQPTKFWADVCSHMDLDELVDDPRFATAE
MSMEG_4798|M.smegmatis_MC2_155 VGLYGTADGRY-----ISFVMMQPTKFWADVCRHMDLEHYIDDPRFATAE
MMAR_4713|M.marinum_M VGVYATSDGRY-----ISLVMMQPTKFWADVCRHIDRPDLAEDPRFATVE
TH_3557|M.thermoresistible__bu VGNYRTKDGRY-----VTLMMLQLDKFFAEAMHAIGLPQVLDDPRFADPA
MAV_2565|M.avium_104 ASIYKTRDNRF-----IAFVLLQADRFWADFCTRLGRTDLIEDERFANAV
MUL_1046|M.ulcerans_Agy99 MNNYTAGDGRR-----FWIVGLEIDRHWPALCRVVERPDWLADPRYGDAR
Mb3300|M.bovis_AF2122/97 VGFATQPSDAFRTADGYIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQR
Rv3272|M.tuberculosis_H37Rv VGFATQPSDAFRTADGYIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQR
MAB_4651c|M.abscessus_ATCC_199 -NIYQSADGSW------VVIAANQDTVFRRLCEAMGRPELSSDARFANHV
. .. .: : : . * *:.
Mflv_2503|M.gilvum_PYR-GCK SIAEHTALANEILTEAMAKRPLTEWSERFATLAG-PWAPVQDTLQAAEDA
Mvan_4155|M.vanbaalenii_PYR-1 SIAENTADAAEILKEAMSKRTLAEWSERFATLAG-PWAPVQDTLQAAEDA
MSMEG_4798|M.smegmatis_MC2_155 SIAENTAAAVDILTEAMKKRTLPEWSERFATLAG-PWAPVQDTLQAAQDA
MMAR_4713|M.marinum_M KIAAHTADAVEILTKAISARTLAEWSERFATLAG-PWAPVQDTLQAADDA
TH_3557|M.thermoresistible__bu ARFENRSTLIAMMDEVFAQRTLAEWREALAGLSG-AWGVVQTPGEVCADP
MAV_2565|M.avium_104 VRFGNRQECIGELRSAFESQDLSHWEKAFAGFDG-VWDVMHTAHEVHSDP
MUL_1046|M.ulcerans_Agy99 GRATNAVELIAQLDQIFATRSLAEWTEIFDAEPDFFWSPINSLEDIVADE
Mb3300|M.bovis_AF2122/97 SRSINYAELTAELELALASKTATEWVQLLQANGL-MACLAHTWKQVVDTP
Rv3272|M.tuberculosis_H37Rv SRSINYAELTAELELALASKTATEWVQLLQANGL-MACLAHTWKQVVDTP
MAB_4651c|M.abscessus_ATCC_199 ARGRNQDDLDAIIAQWAAQRLPTDIIDVLSAAGV-IAGPINTVADVVQDP
: : : .. . : : :
Mflv_2503|M.gilvum_PYR-GCK QIRANEYLVQAGEL-------ELVSNPVQFDVAAPVS-GPAPGFAEQTDD
Mvan_4155|M.vanbaalenii_PYR-1 QVRANEYLVQAGEL-------ELVANPVQFDVAAPAS-GPAPGFAEQTDD
MSMEG_4798|M.smegmatis_MC2_155 QIRANEYLVQAGEL-------ELVTNPVQFDVSAPSP-GPAPGFAEQTDD
MMAR_4713|M.marinum_M QVRANEYVVRAGEL-------ELVANPVQFDVAAPQT-GPAPGFAEQTDD
TH_3557|M.thermoresistible__bu AVTANGYIAHTTTMNG--VPYAIPVNPVQFDRHHVVP-DGAPEHGQHTEE
MAV_2565|M.avium_104 QVIANGYLPRVTDAND--NEFALAASPVQFDEAPLDL-TCAPGHGEHTDA
MUL_1046|M.ulcerans_Agy99 QFHAAGGIVDVPDG-A--SSVPMVATPADFHGTPCTPRSVAPQLGQHTDQ
Mb3300|M.bovis_AF2122/97 LFAESDLTLEVGRG-A--DTITVIRTPARYASFRAVVTDPPPTAGEHNAV
Rv3272|M.tuberculosis_H37Rv LFAENDLTLEVGRG-A--DTITVIRTPARYASFRAVVTDPPPTAGEHNAV
MAB_4651c|M.abscessus_ATCC_199 QLKAREMLVEHFDERLGRSVLGPGVVPVLSESPGGVRNAGPARPGQDNDD
. *. .. .:..
Mflv_2503|M.gilvum_PYR-GCK ILVELGLDWDRIIELKTAGAVT
Mvan_4155|M.vanbaalenii_PYR-1 ILVELGLDWDRIIELKTAGAVT
MSMEG_4798|M.smegmatis_MC2_155 ILAELGLDWDRIIELKTAGAVT
MMAR_4713|M.marinum_M ILLELGFDWDRIIELKTAGAVT
TH_3557|M.thermoresistible__bu VLLDAGLGWDAIERYKQMGAVL
MAV_2565|M.avium_104 LLAELGFSEEEIIEFKINSVVL
MUL_1046|M.ulcerans_Agy99 VLGELAARRRS-----------
Mb3300|M.bovis_AF2122/97 FLARP-----------------
Rv3272|M.tuberculosis_H37Rv FLARP-----------------
MAB_4651c|M.abscessus_ATCC_199 VYVGLLGKSAQDIERLRAEGVL
.