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MSDILSGIRVVELAAWTFVPAAGAVLADWGADVIKIEHPETGDPQRGLISSGIVTAAGGVNHFIEQPNRG KRSIGLDTSTPEGLELLMKLLETADVFVTNLLPDSRQRMGIDVEQVRARNPKIIYARGHGYGTKGDLASQ GGFDLAAYWARGGIGEGYAAGDGSYPPIQRPAFGDSYGGLAIAGGIAAALVKRERTGEPSVVDVSLLNAA IWQLGPDIVGSGVTGQDIPKFNLDEMPNPVASIYKTRDGRFIAFVLLQADRFWADFCTRLGRPDLIDDER FTNAMVRFENRKDCIAQIRSAFAAEDLSHWEKAFAGFDGVWDVMRTAHELHADPQAIKNGYLPRVTDANN NEFALAASPVQFDETPLDLTCAPGHGEHTDALLAELGFNEEEIIDLKVKSVVL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1826 | - | - | 100% (403) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. avium 104 | MAV_2565 | - | 0.0 | 91.56% (403) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. avium 104 | MAV_0945 | - | 1e-91 | 44.78% (402) | L-carnitine dehydratase/bile acid-inducible protein F |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 2e-32 | 29.19% (322) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_2503 | - | 2e-89 | 44.83% (406) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. tuberculosis H37Rv | Rv3272 | - | 2e-32 | 29.19% (322) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4651c | - | 7e-30 | 33.65% (312) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_4713 | - | 6e-93 | 45.32% (406) | dehydratase |
| M. smegmatis MC2 155 | MSMEG_4798 | - | 4e-89 | 44.53% (411) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. thermoresistible (build 8) | TH_3557 | - | 1e-102 | 48.23% (396) | PUTATIVE putative L-carnitine dehydratase/bile acid-inducible |
| M. ulcerans Agy99 | MUL_1046 | - | 2e-64 | 38.14% (388) | acyl-CoA transferase |
| M. vanbaalenii PYR-1 | Mvan_4155 | - | 6e-91 | 44.33% (406) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1826|M.avium_104 -----MSDILSGIRVVELAAWTFVPAAGAVLADWGADVIKIEHPETGDPQ
TH_3557|M.thermoresistible__bu --------------VLEVAAWTFVPSAGAVLAEWGAEVIKVEPVAGGDPQ
Mflv_2503|M.gilvum_PYR-GCK -----MSKPLDGIRVLEVAMYGFVPSAGAVLAEWGADVIKVEHAVTGDPQ
Mvan_4155|M.vanbaalenii_PYR-1 -----MSKPLDGIRVLEVAMYGFVPSAGAVLAEWGADVIKVEHAVTGDPQ
MSMEG_4798|M.smegmatis_MC2_155 -----MSGPLEGIRILEVAMYGFVPSAGAVLGEWGADVIKVEHAVTGDPQ
MMAR_4713|M.marinum_M ------MKPLEGIRVLEVAMYGFVPSAGAVLAEWGADVIKVEHAVTGDPQ
MUL_1046|M.ulcerans_Agy99 -----MAGPVEGIKVVELGVWVAAPAAAAILADWGADVIKIEPPAG---D
Mb3300|M.bovis_AF2122/97 MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGG---E
Rv3272|M.tuberculosis_H37Rv MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGG---E
MAB_4651c|M.abscessus_ATCC_199 -----MTGALDGIRVLELGTLIAGPFAGRLLGDMGAEVLKIEPPGAPDPL
:::. * *. :* : **:*:*:*
MAV_1826|M.avium_104 RGLISSGIVTAAGG-VNHFIEQPNRGKRSIGLDTSTPEGLELLMKLLETA
TH_3557|M.thermoresistible__bu RGLVTMGIVDEGGGVVNYMIEIPNRGKKSIGVDLLNPAGQEVVHELAKTC
Mflv_2503|M.gilvum_PYR-GCK RGLRQTGLLRVEGD-PNPNIEHANRLKRSIGLDMSVPEGKEVLLELARRA
Mvan_4155|M.vanbaalenii_PYR-1 RGLRQTGLLRVEGD-PNPNIEHANRLKRSIGLDMSVAEGREVLLELARRA
MSMEG_4798|M.smegmatis_MC2_155 RGLRQTGPLRVDGD-PNPNIEHANRGKRSIGLDMSVPAGREVLLELARRA
MMAR_4713|M.marinum_M RGLRQTGMLRVEGD-PNPNIEHANRGKRSLGLDMSISEGKEVLHELARRS
MUL_1046|M.ulcerans_Agy99 PGRLFGRMLGCDLG-MNPPFEMDNRCKRSVVLDLSTDTGRELAYELLSDA
Mb3300|M.bovis_AF2122/97 AARQITSVLPGRPP-LATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTA
Rv3272|M.tuberculosis_H37Rv AARQITSVLPGRPP-LATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTA
MAB_4651c|M.abscessus_ATCC_199 RTWGQAEVDG-----HHVFWTVHARNKKAITLDLRTEAGRALFLDLVDKS
* *::: :* . * .
MAV_1826|M.avium_104 DVFVTNLLPDSRQRMGIDVEQVRARNPKIIYARGHGYGTKGDLASQGGFD
TH_3557|M.thermoresistible__bu DVFLTSYLPGRRRRMRIDVEDIRAVNPNIVYVRGSGHGPDGPDADKPGYD
Mflv_2503|M.gilvum_PYR-GCK DVFLTSFLPGHRQKFGIDVDDIRAVNPKIIYARGSALGPRGEESVKGGYD
Mvan_4155|M.vanbaalenii_PYR-1 DVFLTSFLPGHRQKFGIDVDDIRAANPKIVYARGSALGPRGEESVKGGYD
MSMEG_4798|M.smegmatis_MC2_155 DVFLTSFLPGHREKFGIDVDDIRAVNPKIIYARGSALGPRGEESVKGGYD
MMAR_4713|M.marinum_M DVFLTSFLPGARRKFGIDLEDIRAVNPSIIYARGSALGPRGEEAAKGGYD
MUL_1046|M.ulcerans_Agy99 DVFITNVRPAALRGLGLDFAAVSDRNPRLVYGLITGYGETGPDADRAAYD
Mb3300|M.bovis_AF2122/97 DVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGID
Rv3272|M.tuberculosis_H37Rv DVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGID
MAB_4651c|M.abscessus_ATCC_199 DVIVENFRPGTLERWGLGYDVLAQRNKGIILVRVSGYGQTGPDAHKAGYA
**.: * . :. : * :: . * * . : .
MAV_1826|M.avium_104 LAAYWARGGIGEGYAAGDGSYPPIQ-RPAFGDSYGGLAIAGGIAAALVKR
TH_3557|M.thermoresistible__bu GVSYWSRGGIAH-VLTEDAEELVRS-RPAFGDLLGGMTIAGGIAAALYKR
Mflv_2503|M.gilvum_PYR-GCK MTAFWCRAGTAATITPPGTPGMVGPPGPAYGDTISGTNLAGGIAAALLKR
Mvan_4155|M.vanbaalenii_PYR-1 MTAFWCRAGTAATITPPGTPGMVGPPGPAYGDTISGTNLAGGIAAALLKR
MSMEG_4798|M.smegmatis_MC2_155 MTAFWCRAGAAATITPPGIEGMIGPPGPAYGDTISGTNLAGGIAAALFKR
MMAR_4713|M.marinum_M MTAFWCRAGTAATITPMGYQGMINPPGPAYGDTISGTNLAGGIAAALLKR
MUL_1046|M.ulcerans_Agy99 VAAFWSRGGLAHLLTRPGDTPPFQR--GGMGDHTTGMTLAAAVCAAPLAR
Mb3300|M.bovis_AF2122/97 LVVAAEAG-MTTGMPTPEGKPQIIP--FQLVDNASGHVLAQAVLAALLHR
Rv3272|M.tuberculosis_H37Rv LVVAAEAG-MTTGMPTPEGKPQIIP--FQLVDNASGHVLAQAVLAALLHR
MAB_4651c|M.abscessus_ATCC_199 SVAEAASG-LRHLNGFPGGPPPRMA--LSIGDTLAGMFAAQGALAALYRR
. . * * * . ** *
MAV_1826|M.avium_104 ERTGEPSVVDVSLLNAAIWQLGPDIVGSGVTG---QDIPKFNLDEMPNPV
TH_3557|M.thermoresistible__bu ATTGEGSVVDVSLLGLAAWNLSPDIAVSQIHGG--SSIPTFGHADAPNPL
Mflv_2503|M.gilvum_PYR-GCK ERSGEPSVVDVSLLGSGLWALGHTVALTTHLGQRMEAFPPGVHGSPINPL
Mvan_4155|M.vanbaalenii_PYR-1 ERTGEPSIVDVSLLGSGLWALGHTVALTNHLHERMEAFPPGAHGSPINPL
MSMEG_4798|M.smegmatis_MC2_155 ERTGEPSVVDVSLLGSGLWAMGHTIALTSHLNELMVQPPPGVHGSPINPL
MMAR_4713|M.marinum_M ERTGEPSVVDVSLLGSGLWSLGHTVALTRHLGQRLEAPPPGIHGSPINPL
MUL_1046|M.ulcerans_Agy99 ERTGTGQLVSTSLYRQGAYTVSFDLNTYLLTG---QQIAIGQRESMGNPC
Mb3300|M.bovis_AF2122/97 ERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKG
Rv3272|M.tuberculosis_H37Rv ERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKG
MAB_4651c|M.abscessus_ATCC_199 TVTGRGQVVDAALTESCLAVQESTIPDYDVGRVVRGPSGTRLEGIAPS--
.* .:*..:: :
MAV_1826|M.avium_104 ASIYKTRDGRF-----IAFVLLQADRFWADFCTRLGRPDLIDDERFTNAM
TH_3557|M.thermoresistible__bu VGNYRTKDGRY-----VTLMMLQLDKFFAEAMHAIGLPQVLDDPRFADPA
Mflv_2503|M.gilvum_PYR-GCK VGLYATADDRY-----ISFVMMQPTKFWADVCKHMDLDELADDPRFATAE
Mvan_4155|M.vanbaalenii_PYR-1 VGLYPTADDRY-----ISFVMMQPTKFWADVCSHMDLDELVDDPRFATAE
MSMEG_4798|M.smegmatis_MC2_155 VGLYGTADGRY-----ISFVMMQPTKFWADVCRHMDLEHYIDDPRFATAE
MMAR_4713|M.marinum_M VGVYATSDGRY-----ISLVMMQPTKFWADVCRHIDRPDLAEDPRFATVE
MUL_1046|M.ulcerans_Agy99 MNNYTAGDGRR-----FWIVGLEIDRHWPALCRVVERPDWLADPRYGDAR
Mb3300|M.bovis_AF2122/97 VGFATQPSDAFRTADGYIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQR
Rv3272|M.tuberculosis_H37Rv VGFATQPSDAFRTADGYIVISAYVPKHWQKLCYLIGRPDLVEDQRFAEQR
MAB_4651c|M.abscessus_ATCC_199 -NIYQSADGSW------VVIAANQDTVFRRLCEAMGRPELSSDARFANHV
. .. .: : : . * *:
MAV_1826|M.avium_104 VRFENRKDCIAQIRSAFAAEDLSHWEKAFAGFDG-VWDVMRTAHELHADP
TH_3557|M.thermoresistible__bu ARFENRSTLIAMMDEVFAQRTLAEWREALAGLSG-AWGVVQTPGEVCADP
Mflv_2503|M.gilvum_PYR-GCK SIAEHTALANEILTEAMAKRPLTEWSERFATLAG-PWAPVQDTLQAAEDA
Mvan_4155|M.vanbaalenii_PYR-1 SIAENTADAAEILKEAMSKRTLAEWSERFATLAG-PWAPVQDTLQAAEDA
MSMEG_4798|M.smegmatis_MC2_155 SIAENTAAAVDILTEAMKKRTLPEWSERFATLAG-PWAPVQDTLQAAQDA
MMAR_4713|M.marinum_M KIAAHTADAVEILTKAISARTLAEWSERFATLAG-PWAPVQDTLQAADDA
MUL_1046|M.ulcerans_Agy99 GRATNAVELIAQLDQIFATRSLAEWTEIFDAEPDFFWSPINSLEDIVADE
Mb3300|M.bovis_AF2122/97 SRSINYAELTAELELALASKTATEWVQLLQANGL--MACLAHTWKQVVDT
Rv3272|M.tuberculosis_H37Rv SRSINYAELTAELELALASKTATEWVQLLQANGL--MACLAHTWKQVVDT
MAB_4651c|M.abscessus_ATCC_199 ARGRNQDDLDAIIAQWAAQRLPTDIIDVLSAAGV-IAGPINTVADVVQDP
: : . .. . : : . *
MAV_1826|M.avium_104 QAIKNGYLPRVTDANN--NEFALAASPVQFDETPLDL-TCAPGHGEHTDA
TH_3557|M.thermoresistible__bu AVTANGYIAHTTTMNG--VPYAIPVNPVQFDRHHVVP-DGAPEHGQHTEE
Mflv_2503|M.gilvum_PYR-GCK QIRANEYLVQAG-------ELELVSNPVQFDVAAPVS-GPAPGFAEQTDD
Mvan_4155|M.vanbaalenii_PYR-1 QVRANEYLVQAG-------ELELVANPVQFDVAAPAS-GPAPGFAEQTDD
MSMEG_4798|M.smegmatis_MC2_155 QIRANEYLVQAG-------ELELVTNPVQFDVSAPSP-GPAPGFAEQTDD
MMAR_4713|M.marinum_M QVRANEYVVRAG-------ELELVANPVQFDVAAPQT-GPAPGFAEQTDD
MUL_1046|M.ulcerans_Agy99 QFHAAGGIVDVPDG-A--SSVPMVATPADFHGTPCTPRSVAPQLGQHTDQ
Mb3300|M.bovis_AF2122/97 PLFAESDLTLEVGRGA--DTITVIRTPARYASFRAVVTDPPPTAGEHNAV
Rv3272|M.tuberculosis_H37Rv PLFAENDLTLEVGRGA--DTITVIRTPARYASFRAVVTDPPPTAGEHNAV
MAB_4651c|M.abscessus_ATCC_199 QLKAREMLVEHFDERLGRSVLGPGVVPVLSESPGGVRNAGPARPGQDNDD
: *. .. .:..
MAV_1826|M.avium_104 LLAELGFNEEEIIDLKVKSVVL
TH_3557|M.thermoresistible__bu VLLDAGLGWDAIERYKQMGAVL
Mflv_2503|M.gilvum_PYR-GCK ILVELGLDWDRIIELKTAGAVT
Mvan_4155|M.vanbaalenii_PYR-1 ILVELGLDWDRIIELKTAGAVT
MSMEG_4798|M.smegmatis_MC2_155 ILAELGLDWDRIIELKTAGAVT
MMAR_4713|M.marinum_M ILLELGFDWDRIIELKTAGAVT
MUL_1046|M.ulcerans_Agy99 VLGELAARRRS-----------
Mb3300|M.bovis_AF2122/97 FLARP-----------------
Rv3272|M.tuberculosis_H37Rv FLARP-----------------
MAB_4651c|M.abscessus_ATCC_199 VYVGLLGKSAQDIERLRAEGVL
.