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MTTPQFGSQRSDDDNWDIVSSVGYTALLVAGWRALHAVSPRPLVRDDYAKTFIAASGDPYLTGVLANPGT SEDELAFPRLYGVQTRFFDDFFDAAGAAGIRQAVIIAAGLDSRAYRLEWPPATTVFEVDLAKVLEFKARV LGEQGAVPKARRVEVAADLRADWSRPLEAAGFDVESPSAWSVEGLLPYLTDEAQHALFTRISGLSAPGSR IAIGALGSRLDHDQLHALEESHPGVDVSGNVDFSALTYEPQSDPAEWLAAHGWVVDPVRNTLDLQAGYGM TPPEVDVKIDGFMRSQYITAAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2803 | - | - | 100% (302) | methyltransferase, putative, family protein |
| M. avium 104 | MAV_2576 | - | 1e-56 | 44.11% (297) | methyltransferase |
| M. avium 104 | MAV_4557 | - | 6e-56 | 43.54% (294) | methyltransferase, putative, family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1931c | - | 1e-135 | 75.17% (302) | hypothetical protein Mb1931c |
| M. gilvum PYR-GCK | Mflv_0743 | - | 9e-52 | 42.03% (276) | putative methyltransferase |
| M. tuberculosis H37Rv | Rv1896c | - | 1e-135 | 75.17% (302) | hypothetical protein Rv1896c |
| M. leprae Br4923 | MLBr_02020 | - | 1e-136 | 77.33% (300) | hypothetical protein MLBr_02020 |
| M. abscessus ATCC 19977 | MAB_4584c | - | 1e-65 | 47.54% (305) | hypothetical protein MAB_4584c |
| M. marinum M | MMAR_2791 | - | 1e-126 | 72.52% (302) | hypothetical protein MMAR_2791 |
| M. smegmatis MC2 155 | MSMEG_0093 | - | 2e-54 | 42.18% (294) | methyltransferase |
| M. thermoresistible (build 8) | TH_2759 | - | 4e-59 | 42.81% (313) | PUTATIVE methyltransferase |
| M. ulcerans Agy99 | MUL_2961 | - | 1e-124 | 72.19% (302) | hypothetical protein MUL_2961 |
| M. vanbaalenii PYR-1 | Mvan_0104 | - | 4e-56 | 44.93% (276) | putative methyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1931c|M.bovis_AF2122/97 ---MTTPEYGSL-RSDDDHWDIVSNVGYTALLVAGWRALHTTGPKPLVQD
Rv1896c|M.tuberculosis_H37Rv ---MTTPEYGSL-RSDDDHWDIVSNVGYTALLVAGWRALHTTGPKPLVQD
MAV_2803|M.avium_104 ---MTTPQFGSQ-RSDDDNWDIVSSVGYTALLVAGWRALHAVSPRPLVRD
MLBr_02020|M.leprae_Br4923 -MMAATPEFGSL-RSDDDHWDIVSSVGYTALLVAGWRALHAVGPQPLVRD
MMAR_2791|M.marinum_M ---MTTSEYGSR-RSDDDQWDIVSGVGYTALLVAGWRALDTVGPQPLAPD
MUL_2961|M.ulcerans_Agy99 ---MTTSEYGSR-RSDDDQWDIVSGVGYTALLVAGWRALDTVGPQPLAPD
MAB_4584c|M.abscessus_ATCC_199 ---MTNIEDKDWSRSEGDSWDIVSSVGFTALGVAAARAVENREADPLVRD
Mflv_0743|M.gilvum_PYR-GCK ---------MSSLRTDDDTWDIASSVGATAVMVAAARAAETERHDALIND
Mvan_0104|M.vanbaalenii_PYR-1 ---------MSSLRTDNDTWDIASSVGATAVMVAAARAAETERPEPLIDD
MSMEG_0093|M.smegmatis_MC2_155 ---MTDVRETPSVRSARDSWGITESVGATALGVAAARAAETAQADPLIRD
TH_2759|M.thermoresistible__bu MVMMFDVTEAASARSEGDSWDITESVGATALGVAAERALETSQPDPLIRD
*: * *.*...** **: **. ** . .* *
Mb1931c|M.bovis_AF2122/97 EYAKHFITASADPYLEGLLANP----------RTSEDGTAFPRLYGVQTR
Rv1896c|M.tuberculosis_H37Rv EYAKHFITASADPYLEGLLANP----------RTSEDGTAFPRLYGVQTR
MAV_2803|M.avium_104 DYAKTFIAASGDPYLTGVLANP----------GTSEDELAFPRLYGVQTR
MLBr_02020|M.leprae_Br4923 EYAKYFITASRDPYLMNLLANP----------GTSLNETAFPRLYGVQTR
MMAR_2791|M.marinum_M EYAKYFIAASGDAYLNDQLAHP----------PTSVDETAFPRLYGVQTR
MUL_2961|M.ulcerans_Agy99 EYAKYFIAASGDAYLNDQLAHP----------PTSVDETAFPRLYGVQTR
MAB_4584c|M.abscessus_ATCC_199 PYAEHFVRAAGEPHLIGLLDSSE---------PKPPNPGTAPRHIGLRSK
Mflv_0743|M.gilvum_PYR-GCK PYAKVLVEGAGAGAWRFIADEDLVAKASESDTEVGALFEHMKNYQAVRTH
Mvan_0104|M.vanbaalenii_PYR-1 PYAKILVAGAGNGAWQYIADDGFVAKVTESDPEIGPLFEHMKNYQAVRTH
MSMEG_0093|M.smegmatis_MC2_155 EFAFLLVSAAGP-TWAQMAVSDPHWLG--ADADARRIHEISRNYQAVRTH
TH_2759|M.thermoresistible__bu EYAFLLVSAAGP-PWTQLASSDLSWLG--DDETARRMHLMSRDYQAVRTH
:* :: .: .::::
Mb1931c|M.bovis_AF2122/97 FFDDFFNCADEAGIRQAVIVAAGLDCRAYRLDWQPGTTVFEIDVPKVLEF
Rv1896c|M.tuberculosis_H37Rv FFDDFFNCADEAGIRQAVIVAAGLDCRAYRLDWQPGTTVFEIDVPKVLEF
MAV_2803|M.avium_104 FFDDFFDAAGAAGIRQAVIIAAGLDSRAYRLEWPPATTVFEVDLAKVLEF
MLBr_02020|M.leprae_Br4923 FFDDFFSSAGDTGIRQAVIVAAGLDSRAYRLKWPNGATVFEIDLPKVLEF
MMAR_2791|M.marinum_M FFDDFFRSAAAAGTKQAVIVAAGLDSRAYRLEWPSGTTVFEIDLPQVLEF
MUL_2961|M.ulcerans_Agy99 FFDDFFR-SAAAGTKQAVIVAAGLDSRAYRLEWPSGTTVFEIDLAQVLEF
MAB_4584c|M.abscessus_ATCC_199 FFDEFFINATNSGCKQAVILAAGLDVRAHRLPWPAGTKVFELDQPQVLEF
Mflv_0743|M.gilvum_PYR-GCK FFDAFFSAAVDAGVRQIVILASGLDSRAFRLPWPAGTVVYEIDQPLVLDY
Mvan_0104|M.vanbaalenii_PYR-1 FFDAFFAAAVDAGIRQIVILASGLDSRAFRLPWPAGTTVFEIDQPLVLAY
MSMEG_0093|M.smegmatis_MC2_155 YFDEYFSDVAHAGIRQVVILAAGLDSRAFRLDWPAGTTVFEIDQPKVLEY
TH_2759|M.thermoresistible__bu YFDRYFAAAARAGIRQIVLLAAGLDSRAYRLDWPAGTVVYELDQPRVLDF
:** :* :* :* *::*:*** **.** * .: *:*:* . ** :
Mb1931c|M.bovis_AF2122/97 KARVLSERGAVPKAHRVAVPADLRTDWPTPLTAAGFDPQRPSAWSVEGLL
Rv1896c|M.tuberculosis_H37Rv KARVLSERGAVPKAHRVAVPADLRTDWPTPLTAAGFDPQRPSAWSVEGLL
MAV_2803|M.avium_104 KARVLGEQGAVPKARRVEVAADLRADWSRPLEAAGFDVESPSAWSVEGLL
MLBr_02020|M.leprae_Br4923 KARVLAEQGAIPNAGRSEVAADLRADWPRALKAAGFDPQRSSAWSVEGLL
MMAR_2791|M.marinum_M KARVLQRHGVEPKARRNEVAADLRTDWPATLHAAGFEPGQPSAWSVEGLL
MUL_2961|M.ulcerans_Agy99 KARVLQRHGVEPKARRNAVAADLRTDWPATLHAAGFEPGQPSAWSVEGLL
MAB_4584c|M.abscessus_ATCC_199 KDRVLAEHDATPTSDRREIAVDLRDDWPAALLAAGFDPEVPTAWSAEGLI
Mflv_0743|M.gilvum_PYR-GCK KSSTLAAHGVAPTAERREVPIDLRQDWPAALVATGFDPARPTAWLAEGLL
Mvan_0104|M.vanbaalenii_PYR-1 KSSTLASHGVQPTADRREVPIDLRQDWPTALTHAGFDADQPTAWLAEGLL
MSMEG_0093|M.smegmatis_MC2_155 KTATLDAHGAVAKARYVPVPADLRDDWPAALVEAGFDPAQPTAWLAEGLL
TH_2759|M.thermoresistible__bu KNRTLQAHGAVAKADRRTVAVDLRDDWPAALRHAGFDSAAPTAWLAEGLL
* .* :.. ..: :. *** **. .* :**: .:** .***:
Mb1931c|M.bovis_AF2122/97 PYLTGDAQYALFARIDELCAPGSRVALGALGSRLDH---EQLAALETAHP
Rv1896c|M.tuberculosis_H37Rv PYLTGDAQYALFARIDELCAPGSRVALGALGSRLDH---EQLAALETAHP
MAV_2803|M.avium_104 PYLTDEAQHALFTRISGLSAPGSRIAIGALGSRLDH---DQLHALEESHP
MLBr_02020|M.leprae_Br4923 PYLTNDAQSALFTRIGELCAPGSRIAVGALGSRLDR---KQLAALEATHP
MMAR_2791|M.marinum_M PYLTADAQDALFARIDDLCAPGSRIATGALGSRLDH---DQLVALEQTHP
MUL_2961|M.ulcerans_Agy99 PYLTADAQDALFARIDDLCAPGSRIATGALGSRLDH---DQLVALEQTHP
MAB_4584c|M.abscessus_ATCC_199 IYLPSAAQDLLFERVVALSAPGSQVAVEATRGRPDI---AKWGEMQKKYA
Mflv_0743|M.gilvum_PYR-GCK MYLPADAQDRLFAQITELSAPGSQVAAESMGVHAP----DRRERMRERFA
Mvan_0104|M.vanbaalenii_PYR-1 MYLPADAQDRLFAQITELSAPGSRVAAESMGIHAQ----DRRERMRERFA
MSMEG_0093|M.smegmatis_MC2_155 PYLPADAQDRLFELVGVNSAPGSRIAVEAFNMSPERYTEERRAQRRARGE
TH_2759|M.thermoresistible__bu CYLPADAQDRLFERITALSAPGSWLAVEAFHHDPQRATERRRAEWRDRTA
**. ** ** : .**** :* : : .
Mb1931c|M.bovis_AF2122/97 ---GVNMSGDVNFSALTYDD--KTDPVEWLVEHGWAVDPVRSTLELQVGY
Rv1896c|M.tuberculosis_H37Rv ---GVNMSGDVNFSALTYDD--KTDPVEWLVEHGWAVDPVRSTLELQVGY
MAV_2803|M.avium_104 ---GVDVSGNVDFSALTYEP--QSDPAEWLAAHGWVVDPVRNTLDLQAGY
MLBr_02020|M.leprae_Br4923 ---GVNISGDVDFSALTYEP--KTDSAQWLAAHGWAVEPVRNTLELQTSY
MMAR_2791|M.marinum_M ---GVNLSGDVNFSALTYDD--KTNPAQWLAARGWVVEPVRNTLELEAGY
MUL_2961|M.ulcerans_Agy99 ---GVNLFGDVNFSALTYDD--KTNPAQWLAARGWVVEPVRNTLELEAGY
MAB_4584c|M.abscessus_ATCC_199 DE-GHPMS-KVDITTLFYDEE-RADVAEWLAARGWKVQGS-HALELAAAY
Mflv_0743|M.gilvum_PYR-GCK SIASQIDIEPMDITELTYEDPDRAEVAEWLAAHGWTAQAVPSQDAMRR--
Mvan_0104|M.vanbaalenii_PYR-1 SITAQFDVEPMDITELTYEDPDRADVAQWLTAHGWRAEAVPSQDEMRR--
MSMEG_0093|M.smegmatis_MC2_155 QMRKQLDLD-IDVDALMYTADDRADAAQWLSEHGWQVEAVPSADEMAR--
TH_2759|M.thermoresistible__bu RMKAALDLN-LDFEALTYDDPDRADAGEWLAAHGWHPDSVPGTEEMAR--
::. * * ::: :** :** : :
Mb1931c|M.bovis_AF2122/97 GLTPPDVDVKIDSFMRS-QYITAVRA-----
Rv1896c|M.tuberculosis_H37Rv GLTPPDVDVKIDSFMRS-QYITAVRA-----
MAV_2803|M.avium_104 GMTPPEVDVKIDGFMRS-QYITAAR------
MLBr_02020|M.leprae_Br4923 GMTPPDVDVQMDSFMHS-QYITATR------
MMAR_2791|M.marinum_M GMTPPAVDVRLDAIMHS-EYIVATKP-----
MUL_2961|M.ulcerans_Agy99 GMTPPAVDVRLDAIMHS-EYIVATKP-----
MAB_4584c|M.abscessus_ATCC_199 GVEIPELPEDVVEVVKQGNYVTAVLPS----
Mflv_0743|M.gilvum_PYR-GCK -LDRYVEVADSDGQSFS-TFTTGTKL-----
Mvan_0104|M.vanbaalenii_PYR-1 -LHRLVEIADGDDQSFS-TFTTAVKR-----
MSMEG_0093|M.smegmatis_MC2_155 -LGRPAAEADLAEFGMD-GVLMRARLDGERL
TH_2759|M.thermoresistible__bu -MGRP-VPADLLDVAVP-STLLRAHLNGASR
: .