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VNAPAGISLDNWLSPPYARWSFQHVEDFVPTAVIARGTGPVAAIPAAPSELAEIRVAVTDGTASTVGAVM AGTATDGWAVAHRGAMIAEHYLEGMRRQTRHLLFSVSKSLVAAVVGALHGAGAIELDAPVTKYIPALANC GYAGATVRHLLDMRSGVAFSENYDDPAAQIHLLDQAVGWAPNHRPDAPATLRDFLLTLRQKSVHGGPFEY RSCETDVLGWICEVAADQPMPALMSELLWSRIGAQRDATIAVDPAGTGFFDGGISACLTDMIRFGSLFLR EGVSLTGRRVLPEAWIADTLAGGPDSRRAFAASPDDNEMPGGMYRNQMWLPYPGDNVLLCLGMCGQMIYV NRAAEMVAAKVSTQPHSHEPHMLDTLSAFDAIAYRLAGRTD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2718 | - | - | 100% (391) | beta-lactamase |
| M. avium 104 | MAV_3275 | - | 2e-05 | 36.67% (60) | beta-lactamase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1752 | - | 0.0 | 78.61% (388) | hydrolase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv1723 | - | 0.0 | 78.61% (388) | hydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0330 | - | 1e-08 | 23.32% (253) | Beta-lactamase |
| M. marinum M | MMAR_3387 | - | 1e-174 | 73.72% (392) | hypothetical protein MMAR_3387 |
| M. smegmatis MC2 155 | MSMEG_4455 | - | 1e-06 | 27.78% (162) | beta-lactamase |
| M. thermoresistible (build 8) | TH_0350 | lipP | 7e-07 | 35.71% (126) | PROBABLE ESTERASE/LIPASE LIPP |
| M. ulcerans Agy99 | MUL_2951 | lipD | 7e-05 | 32.18% (87) | lipase LipD |
| M. vanbaalenii PYR-1 | Mvan_2765 | - | 3e-05 | 34.48% (87) | beta-lactamase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1752|M.bovis_AF2122/97 MSGGVPAGLALDNWLSSPYSHWAFQHVEDFMPTTVIARGTEPVVTLPADN
Rv1723|M.tuberculosis_H37Rv MSGGVPAGLALDNWLSSPYSHWAFQHVEDFMPTTVIARGTEPVVTLPADN
MMAR_3387|M.marinum_M MSGGVPAGLSLGNWLSSPYSHWAFQHVEDFMPTALISRGTNPAVALPAAG
MAV_2718|M.avium_104 MN--APAGISLDNWLSPPYARWSFQHVEDFVPTAVIARGTGPVAAIPAAP
MAB_0330|M.abscessus_ATCC_1997 ----MPELSTRCFDESSLMRRILAVVLTIALLVSACGKHSAIVVAELDPQ
MSMEG_4455|M.smegmatis_MC2_155 ------MRIVRALVAAALVAAVSAGCSTSPDAAEEA--FATTEPPALKTI
MUL_2951|M.ulcerans_Agy99 ------------------MAQPSVPTTDDG--------LPSGVAGACDSR
Mvan_2765|M.vanbaalenii_PYR-1 ------------------MTGVNNPERDVALSHGHGAALPCGVQGAADPN
TH_0350|M.thermoresistible__bu ------------------MSETFQPVRSIP-----------AVHGTCAPG
Mb1752|M.bovis_AF2122/97 APIADIGLTSTDGIATTVGAVMAATATDGWAVAHRGALVAEQYLDGLGPR
Rv1723|M.tuberculosis_H37Rv APIADIGLTSTDGIATTVGAVMAATATDGWAVAHRGALVAEQYLDGLGPR
MMAR_3387|M.marinum_M APVADIELTNTEGAPTTVGAVMAGTVTDGWAVAHRGALVAEEYLGGLRPQ
MAV_2718|M.avium_104 SELAEIRVAVTDGTASTVGAVMAGTATDGWAVAHRGAMIAEHYLEGMRRQ
MAB_0330|M.abscessus_ATCC_1997 TTAKLDSAINEILTSAAVPGAIVGVWGPKGQYVRTFGVANTATRAPLRPD
MSMEG_4455|M.smegmatis_MC2_155 DPAHLQSIVADTAKSLDVPGALVLLQTPQGRFAAGVGTTELGTQTPPRPD
MUL_2951|M.ulcerans_Agy99 FSGVVRAFAGLYPGRKFGGGALSVYTEGRQVVDVWTGWADRNGEVPWTAD
Mvan_2765|M.vanbaalenii_PYR-1 FTLAVRAFAQMFPSRRLGGGALAVYLDGEPVVDVWTGWADRRGTRRWTAD
TH_0350|M.thermoresistible__bu FEGVRTAFVDNFTERGEIGAAVAVWVDGELVVDLWGGSADAEGRLSWRRD
..: .
Mb1752|M.bovis_AF2122/97 TRHLLFSVSKSLVAAVVGALHGAGAIELDAPVTAYVPALADCGYAGATVR
Rv1723|M.tuberculosis_H37Rv TRHLLFSVSKSLVAAVVGALHGAGAIELDAPVTAYVPALADCGYAGATVR
MMAR_3387|M.marinum_M TRHLLFSVSKSLVAAVVGALSGAGAIDVDAPVTTYVPALANCGYAGAKVR
MAV_2718|M.avium_104 TRHLLFSVSKSLVAAVVGALHGAGAIELDAPVTKYIPALANCGYAGATVR
MAB_0330|M.abscessus_ATCC_1997 FYHRIGSVTKTFTVTAVLQLVDEGKVELDDPIAKYVDKVPNG--NKITLR
MSMEG_4455|M.smegmatis_MC2_155 THFRIASNTKTMTAAVIMLLAQDGKLSLDDPVAKYVPGVPNA--DAITLI
MUL_2951|M.ulcerans_Agy99 TGAMVFSATKGLAATVIHRLVDRGLLDYDAPVADYWPEFGVKGKSAITVS
Mvan_2765|M.vanbaalenii_PYR-1 TGPMVFSATKGVTATVIHRLHDRGLVDYDAPVAEYWREFGANGKSAITVR
TH_0350|M.thermoresistible__bu TLASVFSGSKGLTATCVHLLADRGEIDLDAPIARYWPEFGQAGKDAITTA
: * :* ...: : * * :. * *:: * . .
Mb1752|M.bovis_AF2122/97 HLLDMRSG-------VAFSENYDDPAAEIHVREQVIGWAPKRGPDLPATL
Rv1723|M.tuberculosis_H37Rv HLLDMRSG-------VAFSENYDDPAAEIHVREQVIGWAPKRGPDLPATL
MMAR_3387|M.marinum_M HLLDMRSG-------VGFSENYDDPAAEIHVREQVIGWAPKHNPDVPATL
MAV_2718|M.avium_104 HLLDMRSG-------VAFSENYDDPAAQIHLLDQAVGWAPNHRPDAPATL
MAB_0330|M.abscessus_ATCC_1997 ELARMQSGLFNYSMSLAFSRDLEADPRRQYSTHELLDYAFAQ-PSNFVPG
MSMEG_4455|M.smegmatis_MC2_155 DLLRMRSGLYCYTNDSEFAATLDSDPAKTWTPQEVLDIAFDH-PSTVAPD
MUL_2951|M.ulcerans_Agy99 DLLRHRSGLSHLKG-VGKKEILDHLRMEEKLAAAPLDRTHGK-MAYHAVT
Mvan_2765|M.vanbaalenii_PYR-1 DALRHRAGLSQLNG-AGKADLLDHAVMEQRLAAAPRSWLYGK-PAYHALT
TH_0350|M.thermoresistible__bu MVLGHRSGVIGPRTPMRPEQTLDWDAVCAALAAAGPWWPPGAAQGYHMVT
::* :
Mb1752|M.bovis_AF2122/97 RDYLLTLRRKSAHGGPFEYRSCETDVLGWICEAAA----GQPMPELMSEL
Rv1723|M.tuberculosis_H37Rv RDYLLTLRRKSAHGGPFEYRSCETDVLGWICEAAA----GQPMPELMSEL
MMAR_3387|M.marinum_M RDYLLTLRQKSAHGGPFEYRSCETDVLGWICEVAG----GQPMPELMSHL
MAV_2718|M.avium_104 RDFLLTLRQKSVHGGPFEYRSCETDVLGWICEVAA----DQPMPALMSEL
MAB_0330|M.abscessus_ATCC_1997 QGYEYSNTNAVLLGQVVEKVSGQTLPAFVQEH--------ITGPLGMRRT
MSMEG_4455|M.smegmatis_MC2_155 TAYEYCNTNYALLGVVAEQVGGAPLAEQFQQR--------LFGPLGMRNT
MUL_2951|M.ulcerans_Agy99 YGWLLSGLARAVTGKGMRDLFREELARPLDTDGLHLGRPPGDAPTTAAQT
Mvan_2765|M.vanbaalenii_PYR-1 FGWLLSGLARSITGKGMRELIRTEVAAPLNTDGLHLGRPPVQAPTEAAQI
TH_0350|M.thermoresistible__bu FGFILGEIVRRVTGRSPGRFLRTEIAEPLGADVHIG--LPHTEHHRCAEM
: * .
Mb1752|M.bovis_AF2122/97 LWSR--------------IGAQCDATIALDVAGAAGTGIFDGGISACLTD
Rv1723|M.tuberculosis_H37Rv LWSR--------------IGAQCDATIALDVAGAAGTGIFDGGISACLTD
MMAR_3387|M.marinum_M LWSR--------------IGAQCDASIALDTAGPAGTGIFDGGINACLTD
MAV_2718|M.avium_104 LWSR--------------IGAQRDATIAVD---PAGTGFFDGGISACLTD
MAB_0330|M.abscessus_ATCC_1997 SFP--------------ETSAIADPHARGYTQLTPTGSLVDS--------
MSMEG_4455|M.smegmatis_MC2_155 LLPS-----------PAEASEIPAPYSHGYMYGETLYAMVDETYPAAITD
MUL_2951|M.ulcerans_Agy99 LLPQSKIPTPLLDFIAPKVAGLSFSGLLGAVYFPGILSMLQDDMPFLDGE
Mvan_2765|M.vanbaalenii_PYR-1 IGPQTRLQNPVFNLVAPRIAALPFSAGFGAIYLPGVKALVQGDTPLLDGE
TH_0350|M.thermoresistible__bu VNKPHIR-------DVLAAGGAPAHPERLDEHPMAGLAVAMGFIPDDELG
. ..
Mb1752|M.bovis_AF2122/97 MIRFGSLYLRDGVSLAGQQVVP--AAWIADTFDGGPDSRQAFAASP---D
Rv1723|M.tuberculosis_H37Rv MIRFGSLYLRDGVSLAGQQVVP--AAWIADTFDGGPDSRQAFAASP---D
MMAR_3387|M.marinum_M MIRFGSLFLRDGVSLTGQQVVP--AAWIADTLDGGTDSRQAFAASP---D
MAV_2718|M.avium_104 MIRFGSLFLREGVSLTGRRVLP--EAWIADTLAGGPDSRRAFAASP---D
MAB_0330|M.abscessus_ATCC_1997 ------------TDWNPSWASW--AGAMISTLDDLRIWVPALATGVLLKP
MSMEG_4455|M.smegmatis_MC2_155 AARAGTLKPNDYTHQNSSYATA--AGGAISTADDLATWIRALVGGKVLDS
MUL_2951|M.ulcerans_Agy99 IPAVNGVVTARALAKTYAALAN--DGVIDGMRLLSSDAVSGLTGKAELWP
Mvan_2765|M.vanbaalenii_PYR-1 IPAANGVATARALARMYGAIAN--GGRIDGTQYLSGETAAALIGRPSLRP
TH_0350|M.thermoresistible__bu SADLTGWRAAEFPATNGHVSAVGLATVYHALAREQLISRGHLERCRMSQG
:
Mb1752|M.bovis_AF2122/97 DNPMPGGMYRNQVWFPYPGSNVALCVGMCGQLIYVNRAAEVVAAKLSTQP
Rv1723|M.tuberculosis_H37Rv DNPMPGGMYRNQVWFPYPGSNVALCVGMCGQLIYVNRAAEVVAAKLSTQP
MMAR_3387|M.marinum_M DTKMPGGMYRNQVWFPYPGSNVALCVGMCGQLIYINRAAQVVGAKLSSRP
MAV_2718|M.avium_104 DNEMPGGMYRNQMWLPYPGDNVLLCLGMCGQMIYVNRAAEMVAAKVSTQP
MAB_0330|M.abscessus_ATCC_1997 DSQQQRLQTVA--MPPVPDDIR-YGLGIFDARG-----WIGHSGSIPGYQ
MSMEG_4455|M.smegmatis_MC2_155 EHQQQFLDSLLPEDPDNPDGGQSYGYGISFQRFGPEAAMYYHGGEMPGFN
MUL_2951|M.ulcerans_Agy99 DLNLGLPFTYHQGYQSPPVPGLLGGYGHIGLGG-TIGWADPESGSAFGYV
Mvan_2765|M.vanbaalenii_PYR-1 DHSMVMPLSFHLGYHGLPFPGVLPGFGHVGLGG-SLGWADPRSGLSFGYV
TH_0350|M.thermoresistible__bu GFDPDLVLGPRVADHGWGLGYMLNQRGHAGPNRRVFGHGGSGGSFGFADL
* ..
Mb1752|M.bovis_AF2122/97 HSHEP--HMLDTLRAFDAVAHELSGIRSSSTNDPQRPSPPAQEASPG---
Rv1723|M.tuberculosis_H37Rv HSHEP--HMLDTLRAFDAVAHELSGIRSSSTNDPQRPSPPAQEASPG---
MMAR_3387|M.marinum_M ASQDDPQQQANTLRAFDVVARELGGITS----------------------
MAV_2718|M.avium_104 HSHEP--HMLDTLSAFDAIAYRLAGRTD----------------------
MAB_0330|M.abscessus_ATCC_1997 TLAIYSPAEQTTVVALLNTD-VAKQPAQPSTLFGTAITKVISPDHVFLLE
MSMEG_4455|M.smegmatis_MC2_155 SFMGYDPDNDVALVIWTNLT-LSPDNKTTANAMLPVVLKEIYSDLSF---
MUL_2951|M.ulcerans_Agy99 HNRLLT-LLLFDIGSFAGLAPLLSSAVSTARREGPLEVPHFGASYRETGQ
Mvan_2765|M.vanbaalenii_PYR-1 HNRLLTPLVLSDQAGFVATAALIRRGAAAARRNGYRPVREYGAPFTDLTA
TH_0350|M.thermoresistible__bu EHRIGYAYVMNNFDATKAHADPRSVALSDAVYSALGVTAHRSAAPVGAAG
Mb1752|M.bovis_AF2122/97 ---------
Rv1723|M.tuberculosis_H37Rv ---------
MMAR_3387|M.marinum_M ---------
MAV_2718|M.avium_104 ---------
MAB_0330|M.abscessus_ATCC_1997 NAIPQPR--
MSMEG_4455|M.smegmatis_MC2_155 ---------
MUL_2951|M.ulcerans_Agy99 QPLAAGETS
Mvan_2765|M.vanbaalenii_PYR-1 TAV------
TH_0350|M.thermoresistible__bu RR-------