For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
aa seq not available
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. thermoresistible (build 8) | TH_0350 | lipP | - | 100% (415) | PROBABLE ESTERASE/LIPASE LIPP |
M. thermoresistible (build 8) | TH_3778 | - | 5e-39 | 33.69% (377) | PUTATIVE beta-lactamase |
M. thermoresistible (build 8) | TH_2342 | lipE | 1e-21 | 31.07% (354) | PROBABLE LIPASE LIPE |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2490 | lipP | 1e-164 | 71.39% (388) | esterase/lipase LipP |
M. gilvum PYR-GCK | Mflv_3647 | - | 2e-41 | 34.51% (368) | beta-lactamase |
M. tuberculosis H37Rv | Rv2463 | lipP | 1e-164 | 71.39% (388) | esterase/lipase LipP |
M. leprae Br4923 | MLBr_00119 | lipE | 5e-17 | 35.53% (152) | putative hydrolase |
M. abscessus ATCC 19977 | MAB_0853 | - | 1e-155 | 64.69% (388) | esterase/lipase LipP |
M. marinum M | MMAR_3810 | lipP | 1e-162 | 70.10% (388) | esterase/lipase LipP |
M. avium 104 | MAV_1709 | lipP | 1e-166 | 71.50% (386) | carboxylesterase, putative |
M. smegmatis MC2 155 | MSMEG_4680 | lipP | 1e-176 | 75.39% (386) | carboxylesterase, putative |
M. ulcerans Agy99 | MUL_3735 | lipP | 1e-155 | 71.43% (364) | esterase/lipase LipP |
M. vanbaalenii PYR-1 | Mvan_5383 | - | 4e-59 | 36.90% (393) | beta-lactamase |
CLUSTAL 2.0.9 multiple sequence alignment Mb2490|M.bovis_AF2122/97 -------------------MNQPDIKGSCASEFTKVRDAFERNFVLRNEV Rv2463|M.tuberculosis_H37Rv -------------------MNQPDIKGSCASEFTKVRDAFERNFVLRNEV MMAR_3810|M.marinum_M -------------------MSDVDIYGSCARKFQRVRAAFERNFAQGMEV MUL_3735|M.ulcerans_Agy99 -----------------------------------------------MEV MAV_1709|M.avium_104 ---------------MSDLKTDAPIHGSCAPDFVGVRDAFERNFTHGGEV TH_0350|M.thermoresistible__bu ---------MS--ETFQPVRSIPAVHGTCAPGFEGVRTAFVDNFTERGEI MSMEG_4680|M.smegmatis_MC2_155 ---------MRPGGSLTGQQLAIPISGTCAPGFERVRTAFEQNFTERNEV MAB_0853|M.abscessus_ATCC_1997 ----------------MSTSLDVAVNGTNSPDFDNVRRAFALNFLENDEL Mvan_5383|M.vanbaalenii_PYR-1 -----------------MWSDMSDVAGLCDPRFESVAAALADEIACGEEL Mflv_3647|M.gilvum_PYR-GCK MTGVNSRERDEALSHGHGGHLPRGVQGAADPNFTCAVRAFAQMFPHRRFG MLBr_00119|M.leprae_Br4923 -MTSDGKIRVPTDLDAVTAIGDEDHSDIDSAAVERIWQATRHWYQAGMHP Mb2490|M.bovis_AF2122/97 GAAVAVWVDGDLVVN--LWGGSADA------GGTRPWQHDTLATVLSGTK Rv2463|M.tuberculosis_H37Rv GAAVAVWVDGDLVVN--LWGGSADA------GGTRPWQHDTLATVLSGTK MMAR_3810|M.marinum_M GAAVAVWVDGDLVVN--LWGGSADA------AGTRPWRQDTLTTVLSGSK MUL_3735|M.ulcerans_Agy99 GAAVAVWVDGDLVVN--LWGGSADA------AGTRPWRQDTLTTVLSGSK MAV_1709|M.avium_104 GAAVAVWVDGSLVVN--LWGGWADA------ARTRPWQQNTLTTVLSGTK TH_0350|M.thermoresistible__bu GAAVAVWVDGELVVD--LWGGSADA------EGRLSWRRDTLASVFSGSK MSMEG_4680|M.smegmatis_MC2_155 GAAVAVWVEGDLVVS--LWGGHADA------ARTRPWREDTLASVYSGSK MAB_0853|M.abscessus_ATCC_1997 GAAVAIWVDGELVVN--LWAGWADE------ARTRPWTEDTLAPVYSGTK Mvan_5383|M.vanbaalenii_PYR-1 GASIAVDLDGELVVD--IWAGYVDR------AKTIPWQRDTIVNFWSCTK Mflv_3647|M.gilvum_PYR-GCK GGALAVYLNGEPVVD--VWTGWADR------RGKRRWTADTAPMVFSATK MLBr_00119|M.leprae_Br4923 AIQLCIRQHGRVVLNRAIGHGWGNAPTDPHDAEKIPVTTDTPFCAYSAAK . :.: .* *:. : * : :* * :* Mb2490|M.bovis_AF2122/97 ALTATCVHQLVDRGELDLHAPVARYWPEFGQAGKQAITLAMVMSHRSGAI Rv2463|M.tuberculosis_H37Rv ALTATCVHQLVDRGELDLHAPVARYWPEFGQAGKQAITLAMVMSHRSGAI MMAR_3810|M.marinum_M ALTATCVHQLADRGELDLHAPVARYWPEFGQAGKEAITVAMVLSHRSGVI MUL_3735|M.ulcerans_Agy99 ALTATCVHQLADRGELNLHAPVARYWPEFRQAGKEAITVAMVLSHRSGVI MAV_1709|M.avium_104 GLSATCVHQLADRGQLDLQAPVARYWPEFAQAGKQDITLAMVMSHRSGVI TH_0350|M.thermoresistible__bu GLTATCVHLLADRGEIDLDAPIARYWPEFGQAGKDAITTAMVLGHRSGVI MSMEG_4680|M.smegmatis_MC2_155 GLTSTCIHLLADRGEIDLDAPVARYWPEFAQAGKRDITVASVLAHRSGTI MAB_0853|M.abscessus_ATCC_1997 GLMSTCVHMLVERGVLDLYAPVARYWPEFGQGGKESITLAMVLGHRSGVI Mvan_5383|M.vanbaalenii_PYR-1 TLTALAALILVDRGELDPFSTVARYWPEFAANGKADIEVRHLLSHTSGVS Mflv_3647|M.gilvum_PYR-GCK GVAATVIHRLADRGLIDYDAPVAEYWREFGVNGKSTITVRELMRHRAGLS MLBr_00119|M.leprae_Br4923 AITATVVHMLVERGHFSLDDRVCEYLPTYTSYGKHRTTIRHVLTHSAGVP : : *.:** :. :..* : ** :: * :* Mb2490|M.bovis_AF2122/97 GPRGR-LGWEQVADWDFVCEQLAAAEPWWQPGAAQGYHMTTFGFILGEVF Rv2463|M.tuberculosis_H37Rv GPRGR-LGWEQVADWDFVCEQLAAAEPWWQPGAAQGYHMTTFGFILGEVF MMAR_3810|M.marinum_M GPNAR-MSWQQVTDWDFVCEQLALAEPRWEPGSAQGYHMTTFGFILGEVF MUL_3735|M.ulcerans_Agy99 GPNAR-MSWQQVTDWDFVCEQLALAEPRWEPGSAQGYHMTTFGFILGEVF MAV_1709|M.avium_104 GPRTR-MRWEQVADWDYVCEQLAAAEPWWEPGTAQGYHMTTFGFIMGEVF TH_0350|M.thermoresistible__bu GPRTP-MRPEQTLDWDAVCAALAAAGPWWPPGAAQGYHMVTFGFILGEIV MSMEG_4680|M.smegmatis_MC2_155 GPREP-MDWREITDWDAVCTRIAASEPWWPPGTAQGYQVVTFGFILGELV MAB_0853|M.abscessus_ATCC_1997 GPRTR-LTPEQAANWDEVCEHIARATPWWEPGTAQGYHMATFGFILGEVV Mvan_5383|M.vanbaalenii_PYR-1 GWQTP-FGVEDIYDWAKATSHLAGQAPWWQPGTASGYHAMNYGHLVGELV Mflv_3647|M.gilvum_PYR-GCK QLNG--AAKTDLMDHLVMEERLAAAPASWLVG-RPAYHAFTFGWLLSGLA MLBr_00119|M.leprae_Br4923 FPTGPRPDVTRADDHAYAQQKLSELRPFYRPGLVHIYHALTWGPLMREII : :: . : * *: .:* :: : Mb2490|M.bovis_AF2122/97 RRVTGRTVGQYLRTEIAEPLGAD-VHIGLHPGEQLRCADLVDKPHIRQLL Rv2463|M.tuberculosis_H37Rv RRVTGRTVGQYLRTEIAEPLGAD-VHIGLHPGEQLRCADLVDKPHIRQLL MMAR_3810|M.marinum_M RRITGRTVGQYLRTEIAEPIGAD-VHIGLSPFDQSRCAERVNKPHARDLL MUL_3735|M.ulcerans_Agy99 RRITGRTVGQYLRTEIAEPIGAD-VHIGLSPFDQSRCAERVNKPHARDLL MAV_1709|M.avium_104 RRVTGRTIGHYLRTEIAGPFGAD-VHIGLPLAEQHRCAERVNKPHARDLL TH_0350|M.thermoresistible__bu RRVTGRSPGRFLRTEIAEPLGAD-VHIGLPHTEHHRCAEMVNKPHIRDVL MSMEG_4680|M.smegmatis_MC2_155 RRVTGRTLGQYLRTEIAEPLGAD-IHIGLPRSEHRRCAEMVNKPTVRGVL MAB_0853|M.abscessus_ATCC_1997 RRTTGKTLGQFLRTEIAEPYGLD-VHVGLPHSEHHRCAELINKPYLRDVF Mvan_5383|M.vanbaalenii_PYR-1 RRITGTPLKDFVAEQIAVPLGAD-VQIGARPEDDHRIAELVPPP-PRDRG Mflv_3647|M.gilvum_PYR-GCK RSVTGTGMRELIRTEVAAPLNTDGIHLGRPPVQAPTQPARIIGPQTRLQN MLBr_00119|M.leprae_Br4923 WTATGKEIRDILAAEILDPLGFRWTNFGVAEEDVP----------LVALS ** : :: * . :.* : Mb2490|M.bovis_AF2122/97 ADVQAPGYPTSLNEHPKAALSVSMGFAPDDELGSNDLQLWRQIEFPGTNG Rv2463|M.tuberculosis_H37Rv ADVQAPGYPTSLNEHPKAALSVSMGFAPDDELGSNDLQLWRQIEFPGTNG MMAR_3810|M.marinum_M ADVQAPSDPTSLDDHPKAGLSIAMGFAPDDELGSNDLHLWRQLEFPGTNA MUL_3735|M.ulcerans_Agy99 ADVQAPSDPTSLDDHPKAGLSIAMGFAPDDELGSNDLHLWRQLEFPGTNA MAV_1709|M.avium_104 ADANAPTDPRSLAEHPKAGLSISMGFAPDDELGSHDLNLWRELEFPGTNG TH_0350|M.thermoresistible__bu AAGGAPAHPERLDEHPMAGLAVAMGFIPDDELGSADLTGWRAAEFPATNG MSMEG_4680|M.smegmatis_MC2_155 ADFGLP-RPTSLDDHPMAGFAVSMDFVPDDELGVHDLSAWRTAEFPSTNG MAB_0853|M.abscessus_ATCC_1997 R--GAPGEFDCMSDHPLAGPLISGDFIPDDEIARKDIALWRALEFPGTNA Mvan_5383|M.vanbaalenii_PYR-1 VDRLPPDHPAVKTFAAFPPGAYGAAHAETEAWRRADIG--GANGHGNARG Mflv_3647|M.gilvum_PYR-GCK PIFNAVAPHIAALPFSAG---FGAMYFPGVKSFVQGDTPLLDGEIPAANG MLBr_00119|M.leprae_Br4923 HATGRPLPPIIAAIFRKAIGGTVHEVIPYTNTPPFLTTIVPSSNTVSTAN : Mb2490|M.bovis_AF2122/97 QVSALGLATFYN-GLAQEKLLS--REHMELVRVSQGGFDTDLVLGPRVAD Rv2463|M.tuberculosis_H37Rv QVSALGLATFYN-GLAQEKLLS--REHMELVRVSQGGFDTDLVLGPRVAD MMAR_3810|M.marinum_M QVSALGLATFYN-ALAQEKLLS--REHMDLVRVSQGGFDTDLVLGPRVAD MUL_3735|M.ulcerans_Agy99 QVSALGLATFYN-ALAQEKLLS--REHMDLVRVSQGGFDTDLVLGPRVAD MAV_1709|M.avium_104 QVSALGLATFYN-ALAQEKLLS--REHMDRVRVCQGGLDTDLVLGPRVAD TH_0350|M.thermoresistible__bu HVSAVGLATVYH-ALAREQLIS--RGHLERCRMSQGGFDPDLVLGPRVAD MSMEG_4680|M.smegmatis_MC2_155 HVSALGMATFYN-ALAQEKLLS--RELMERCRVSQGGFDTDLVLGPRVAD MAB_0853|M.abscessus_ATCC_1997 HVSALGMATFYN-AMALGKLLS--HEHMDVVRVSQGGFDPDVVLGPRVAN Mvan_5383|M.vanbaalenii_PYR-1 LVRALSPISLGG-TANGVQVVD--PRTVELIFAEQSSGMDQVLFVP--LR Mflv_3647|M.gilvum_PYR-GCK VATARALARMYG-AIANEGRIDGLQYLSRETTAVLAGRRSLRLDHSMVMP MLBr_00119|M.leprae_Br4923 ELSRFAEIWLRGGELDGIRVLR--SETLLGAVAECRRLRPDFVVGLMPAR . . : : Mb2490|M.bovis_AF2122/97 HGWGLGYMLNQRGVNGPNP-RIFGHGGLGGSFGFVDLEHRIGYAYVMNRF Rv2463|M.tuberculosis_H37Rv HGWGLGYMLNQRGVNGPNP-RIFGHGGLGGSFGFVDLEHRIGYAYVMNRF MMAR_3810|M.marinum_M HGWGLGYMLNQRAVNGPNQ-KIFGHGGLGGSFGFVDLEHRIGYAYVMNRF MUL_3735|M.ulcerans_Agy99 HGWGLGYMLNQRAVNGPNQ-KIFGHGGLGGSFGFVDLEHRIGYAYVMNRF MAV_1709|M.avium_104 HGWGLGYMLNQRCVNGPNP-RIFGHGGLGGSFGFVDLEHRIGYAYVMNRF TH_0350|M.thermoresistible__bu HGWGLGYMLNQRGHAGPNR-RVFGHGGSGGSFGFADLEHRIGYAYVMNNF MSMEG_4680|M.smegmatis_MC2_155 HGWGLGYMLNQRGVAGPNR-RTFGHGGSGGSFAFVDLEHRIGYAYVMNHF MAB_0853|M.abscessus_ATCC_1997 HGWGLGYMLNQRCYAGPNQ-KTFGHGGSGGSYAFVDLEHRIGYSYVMNQF Mvan_5383|M.vanbaalenii_PYR-1 FGIGFGLPTPQSVPAVPDG-KVCWWGGWGGSLVVMDLDRRATFAYVMNKM Mflv_3647|M.gilvum_PYR-GCK LSFHLGYHGLPIPGLLPG----FGHVGLGGSLGWADPETGLAFGFVHNRL MLBr_00119|M.leprae_Br4923 WGTGFILGTNKFGPFGRNAPAAFGHLGLVNIAIWADPQRSMAAGLISSGK . : . * . * : . : . Mb2490|M.bovis_AF2122/97 DATKANADPRSVVLSNEVYAALGVNRS---------------------- Rv2463|M.tuberculosis_H37Rv DATKANADPRSVVLSNEVYAALGVNRS---------------------- MMAR_3810|M.marinum_M DASKANADPRSVALSNEVYAALDVAAD---------------------- MUL_3735|M.ulcerans_Agy99 DASKANADPRSVALSNEVYAALDVAAD---------------------- MAV_1709|M.avium_104 DATKANADPRSLALSNEVYSVLGVR------------------------ TH_0350|M.thermoresistible__bu DATKAHADPRSVALSDAVYSALGVTAHRSAAPVGAAGRR---------- MSMEG_4680|M.smegmatis_MC2_155 DATKCNADPRTVALSNQVYSALGVI------------------------ MAB_0853|M.abscessus_ATCC_1997 DVTKADADPRSVRLINELYTTLGVSPAGESL------------------ Mvan_5383|M.vanbaalenii_PYR-1 GG-GTTGTPRTVRYAKLIDAALQDARG---------------------- Mflv_3647|M.gilvum_PYR-GCK LTPMVVSDQAGFVATAALLRRGASQARKNGYRRVREYGSPFSDVAATAV MLBr_00119|M.leprae_Br4923 PGQDPNAG-RYGALMNTITAEIPVH------------------------ . :