For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SGGVPAGLSLGNWLSSPYSHWAFQHVEDFMPTALISRGTNPAVALPAAGAPVADIELTNTEGAPTTVGAV MAGTVTDGWAVAHRGALVAEEYLGGLRPQTRHLLFSVSKSLVAAVVGALSGAGAIDVDAPVTTYVPALAN CGYAGAKVRHLLDMRSGVGFSENYDDPAAEIHVREQVIGWAPKHNPDVPATLRDYLLTLRQKSAHGGPFE YRSCETDVLGWICEVAGGQPMPELMSHLLWSRIGAQCDASIALDTAGPAGTGIFDGGINACLTDMIRFGS LFLRDGVSLTGQQVVPAAWIADTLDGGTDSRQAFAASPDDTKMPGGMYRNQVWFPYPGSNVALCVGMCGQ LIYINRAAQVVGAKLSSRPASQDDPQQQANTLRAFDVVARELGGITS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3387 | - | - | 100% (398) | hypothetical protein MMAR_3387 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1752 | - | 0.0 | 83.67% (398) | hydrolase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv1723 | - | 0.0 | 83.67% (398) | hydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1386 | - | 6e-06 | 36.84% (95) | putative esterase/lipase/beta-lactamase |
| M. avium 104 | MAV_2718 | - | 1e-174 | 73.72% (392) | beta-lactamase |
| M. smegmatis MC2 155 | MSMEG_4455 | - | 3e-08 | 29.05% (148) | beta-lactamase |
| M. thermoresistible (build 8) | TH_3778 | - | 5e-05 | 38.98% (59) | PUTATIVE beta-lactamase |
| M. ulcerans Agy99 | MUL_2951 | lipD | 9e-05 | 33.33% (84) | lipase LipD |
| M. vanbaalenii PYR-1 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1752|M.bovis_AF2122/97 MSGGVPAGLALDNWLSSPYSHWAFQHVEDFMPTTVIARGTEPVVTLPADN
Rv1723|M.tuberculosis_H37Rv MSGGVPAGLALDNWLSSPYSHWAFQHVEDFMPTTVIARGTEPVVTLPADN
MMAR_3387|M.marinum_M MSGGVPAGLSLGNWLSSPYSHWAFQHVEDFMPTALISRGTNPAVALPAAG
MAV_2718|M.avium_104 MN--APAGISLDNWLSPPYARWSFQHVEDFVPTAVIARGTGPVAAIPAAP
TH_3778|M.thermoresistible__bu --------------------------------------------------
MUL_2951|M.ulcerans_Agy99 -MAQPSVP-----------------TTDDGLPSGVAGACDSRFSGVVRAF
MAB_1386|M.abscessus_ATCC_1997 -MAIPLGPNVAATAPVRRDGLYPGDQPGLRLPNGVEGWARPELSAVVRTF
MSMEG_4455|M.smegmatis_MC2_155 --------MRIVRALVAAALVAAVSAGCSTSPDAAEEAFATTEPPALKTI
Mb1752|M.bovis_AF2122/97 APIADIGLTSTDGIATTVGAVMAATATDGWAVAHRGALVAEQYLDGLGPR
Rv1723|M.tuberculosis_H37Rv APIADIGLTSTDGIATTVGAVMAATATDGWAVAHRGALVAEQYLDGLGPR
MMAR_3387|M.marinum_M APVADIELTNTEGAPTTVGAVMAGTVTDGWAVAHRGALVAEEYLGGLRPQ
MAV_2718|M.avium_104 SELAEIRVAVTDGTASTVGAVMAGTATDGWAVAHRGAMIAEHYLEGMRRQ
TH_3778|M.thermoresistible__bu ---------------VYLHGEPVVDVWTGYADRRG--------TEYWTAD
MUL_2951|M.ulcerans_Agy99 AGLYPGRKFGGGALSVYTEGRQVVDVWTGWADRNG--------EVPWTAD
MAB_1386|M.abscessus_ATCC_1997 EWMFTKYRLGGGGLSVYVDGEPALDIWAGAAAAG----------QGWTRD
MSMEG_4455|M.smegmatis_MC2_155 DPAHLQSIVADTAKSLDVPGALVLLQTPQGRFAAGVGTTELGTQTPPRPD
. .
Mb1752|M.bovis_AF2122/97 TRHLLFSVSKSLVAAVVGALHGAGAIELDAPVTAYVPALADCGYAGATVR
Rv1723|M.tuberculosis_H37Rv TRHLLFSVSKSLVAAVVGALHGAGAIELDAPVTAYVPALADCGYAGATVR
MMAR_3387|M.marinum_M TRHLLFSVSKSLVAAVVGALSGAGAIDVDAPVTTYVPALANCGYAGAKVR
MAV_2718|M.avium_104 TRHLLFSVSKSLVAAVVGALHGAGAIELDAPVTKYIPALANCGYAGATVR
TH_3778|M.thermoresistible__bu TGAMVFSATKGMAATVVHRLVDRGLLDYDTPVAEYWPEFGANGKAGITVR
MUL_2951|M.ulcerans_Agy99 TGAMVFSATKGLAATVIHRLVDRGLLDYDAPVADYWPEFGVKGKSAITVS
MAB_1386|M.abscessus_ATCC_1997 TGALVFSASKGIAATVIHRLVDRGLITYDAPVARYWPEFGANGKSSITVR
MSMEG_4455|M.smegmatis_MC2_155 THFRIASNTKTMTAAVIMLLAQDGKLSLDDPVAKYVPGVPN--ADAITLI
* : * :* :.*:*: * * : * **: * * . . .:
Mb1752|M.bovis_AF2122/97 HLLDMRSGVAFSENYD---DPAAEIHVREQVIGWAPKRG-----PDLPAT
Rv1723|M.tuberculosis_H37Rv HLLDMRSGVAFSENYD---DPAAEIHVREQVIGWAPKRG-----PDLPAT
MMAR_3387|M.marinum_M HLLDMRSGVGFSENYD---DPAAEIHVREQVIGWAPKHN-----PDVPAT
MAV_2718|M.avium_104 HLLDMRSGVAFSENYD---DPAAQIHLLDQAVGWAPNHR-----PDAPAT
TH_3778|M.thermoresistible__bu DVLRHRAGLSHLNGVS--KADLLDHRRMEERLAAAPVNRLQYGKPAYHAL
MUL_2951|M.ulcerans_Agy99 DLLRHRSGLSHLKGVG--KKEILDHLRMEEKLAAAPLDR-THGKMAYHAV
MAB_1386|M.abscessus_ATCC_1997 QVLDHRAGLSRLEGIAYHAEEIVDHELMERRLAAAPVDK-FYGKRAYHAL
MSMEG_4455|M.smegmatis_MC2_155 DLLRMRSGLYCYTNDS----EFAATLDSDPAKTWTPQEVLDIAFDHPSTV
.:* *:*: . : :* :
Mb1752|M.bovis_AF2122/97 LRD----------YLLTLRRKSAHGG------------PFEYRSCETDVL
Rv1723|M.tuberculosis_H37Rv LRD----------YLLTLRRKSAHGG------------PFEYRSCETDVL
MMAR_3387|M.marinum_M LRD----------YLLTLRQKSAHGG------------PFEYRSCETDVL
MAV_2718|M.avium_104 LRD----------FLLTLRQKSVHGG------------PFEYRSCETDVL
TH_3778|M.thermoresistible__bu TYG----------WLLSGLVRAITGCGMRELVRTELAEPLNTDGLHLGRP
MUL_2951|M.ulcerans_Agy99 TYG----------WLLSGLARAVTGKGMRDLFREELARPLDTDGLHLGRP
MAB_1386|M.abscessus_ATCC_1997 TFG----------WLLAGLARSVTGKDMRELFRTEIADPLGVDGIHLGRP
MSMEG_4455|M.smegmatis_MC2_155 APDTAYEYCNTNYALLGVVAEQVGGAPLAEQFQQRLFGPLGMRNTLLPSP
. ** . * *: .
Mb1752|M.bovis_AF2122/97 GWICEAAAGQPMPELMSELLWSRIGAQCDATIALDVAGAAGTGIFDGGIS
Rv1723|M.tuberculosis_H37Rv GWICEAAAGQPMPELMSELLWSRIGAQCDATIALDVAGAAGTGIFDGGIS
MMAR_3387|M.marinum_M GWICEVAGGQPMPELMSHLLWSRIGAQCDASIALDTAGPAGTGIFDGGIN
MAV_2718|M.avium_104 GWICEVAADQPMPALMSELLWSRIGAQRDATIAVD---PAGTGFFDGGIS
TH_3778|M.thermoresistible__bu PAGAPTKAAQILAPQGALD-IPVVGAVVPRLAASQ-----ASAMFGAMYF
MUL_2951|M.ulcerans_Agy99 PGDAPTTAAQTLLPQSKIP-TPLLDFIAPKVAGLS-----FSGLLGAVYF
MAB_1386|M.abscessus_ATCC_1997 PRTASTKAASMYPFLDSMANKPAVGRLLPTVIRAIDRLPGFEGAIGTMYG
MSMEG_4455|M.smegmatis_MC2_155 AEASEIPAPYSHGYMYGETLYAMVDETYPAAITDAAR----AGTLKPNDY
. . . :. . :
Mb1752|M.bovis_AF2122/97 ACLTDMIRFG---SLYLRDGVSLAGQQVVPAAWIADTFDGGPDSRQAFAA
Rv1723|M.tuberculosis_H37Rv ACLTDMIRFG---SLYLRDGVSLAGQQVVPAAWIADTFDGGPDSRQAFAA
MMAR_3387|M.marinum_M ACLTDMIRFG---SLFLRDGVSLTGQQVVPAAWIADTLDGGTDSRQAFAA
MAV_2718|M.avium_104 ACLTDMIRFG---SLFLREGVSLTGRRVLPEAWIADTLAGGPDSRRAFAA
TH_3778|M.thermoresistible__bu PGMFSVVQGD----IPFLDSEIPAANAVATARGLAKMYGAIANGGRIDDV
MUL_2951|M.ulcerans_Agy99 PGILSMLQDD----MPFLDGEIPAVNGVVTARALAKTYAALANDGVIDGM
MAB_1386|M.abscessus_ATCC_1997 PGMERILADDGTLNSALYDMQAPAANAVATAPALAKMYAALAGDGSVDGR
MSMEG_4455|M.smegmatis_MC2_155 THQNSSYATAAGGAISTADDLATWIRALVGG----KVLDSEHQQQFLDSL
. : . : . .
Mb1752|M.bovis_AF2122/97 SPDDNPMPGGMYRNQVWFP----------YPGSNVALCVGMCGQLIYVNR
Rv1723|M.tuberculosis_H37Rv SPDDNPMPGGMYRNQVWFP----------YPGSNVALCVGMCGQLIYVNR
MMAR_3387|M.marinum_M SPDDTKMPGGMYRNQVWFP----------YPGSNVALCVGMCGQLIYINR
MAV_2718|M.avium_104 SPDDNEMPGGMYRNQMWLP----------YPGDNVLLCLGMCGQMIYVNR
TH_3778|M.thermoresistible__bu RFLSPEIVAGLAGRRNLRPDRNLGVPMAFHLGYHGVPF-GIMPGFGHVGL
MUL_2951|M.ulcerans_Agy99 RLLSSDAVSGLTGKAELWPDLNLGLPFTYHQGYQSPPVPGLLGGYGHIGL
MAB_1386|M.abscessus_ATCC_1997 ELLSPETVAGLARKTNLTIDRTIVFPMGMHLGYMSLPMNGFRGGFGHIGL
MSMEG_4455|M.smegmatis_MC2_155 LPEDPDNPDGGQSYGYGISFQRFGPEAAMYYHGGEMPGFNSFMGYDPDND
. * : . .
Mb1752|M.bovis_AF2122/97 AAEVVAAKLSTQPHS----HEP--HMLDTLRAFDAVAHELSGIRSSSTND
Rv1723|M.tuberculosis_H37Rv AAEVVAAKLSTQPHS----HEP--HMLDTLRAFDAVAHELSGIRSSSTND
MMAR_3387|M.marinum_M AAQVVGAKLSSRPAS----QDDPQQQANTLRAFDVVARELGGITS-----
MAV_2718|M.avium_104 AAEMVAAKVSTQPHS----HEP--HMLDTLSAFDAIAYRLAGRTD-----
TH_3778|M.thermoresistible__bu GGSYGWAEPETGLAIGYVHNRLLTPMLIDQAAFVGLNALIRRDAAAARRR
MUL_2951|M.ulcerans_Agy99 GGTIGWADPESGSAFGYVHNRLLTLLLFDIGSFAGLAPLLSSAVSTARRE
MAB_1386|M.abscessus_ATCC_1997 GGSMGWADPKRKIAVGFAHNRLPLTMALDQISFAFLWPQIVKAVG-----
MSMEG_4455|M.smegmatis_MC2_155 VALVIWTNLTLSPDN----------KTTANAMLPVVLKEIYSDLSF----
. :. : : :
Mb1752|M.bovis_AF2122/97 PQRPSPPAQEASPG------------
Rv1723|M.tuberculosis_H37Rv PQRPSPPAQEASPG------------
MMAR_3387|M.marinum_M --------------------------
MAV_2718|M.avium_104 --------------------------
TH_3778|M.thermoresistible__bu GYRPVGDLGAPFDMRKR---VAG---
MUL_2951|M.ulcerans_Agy99 GPLEVPHFGASYRETGQQPLAAGETS
MAB_1386|M.abscessus_ATCC_1997 --------------------------
MSMEG_4455|M.smegmatis_MC2_155 --------------------------