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PSRRVLITGASRGIGRAVADRLAEGGHEPIGLARSAPEDFPGEFYEVDLADPYATAATLDKIVGHAAVHA VVNNVGFARFGRLGSIELDHLFDTYDLNVRAAVQVVQAALPGMLDAEWGRIVNVTSLTTLGTPERTPYAA AKAALEACTRIWAGELASAGITVNAVAPGPTETDMYRERSPVGSEREARFLQSIPLHRVARPREIAHAIC FLLDEDAGYITGQILRVDGGGSIAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2709 | - | - | 100% (236) | short chain dehydrogenase |
| M. avium 104 | MAV_3295 | fabG | 2e-29 | 36.05% (233) | 3-oxoacyl-(acyl-carrier-protein) reductase |
| M. avium 104 | MAV_0942 | - | 2e-29 | 36.36% (231) | 3-oxoacyl-(acyl-carrier-protein) reductase, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1519 | fabG1 | 1e-27 | 36.02% (236) | 3-oxoacyl- |
| M. gilvum PYR-GCK | Mflv_2501 | - | 9e-35 | 38.03% (234) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1483 | fabG1 | 2e-27 | 36.02% (236) | 3-oxoacyl- |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 2e-29 | 36.48% (233) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0952 | - | 2e-26 | 33.74% (246) | short chain dehydrogenase |
| M. marinum M | MMAR_4715 | - | 4e-32 | 37.50% (232) | 3-oxoacyl- |
| M. smegmatis MC2 155 | MSMEG_0831 | - | 1e-90 | 68.51% (235) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_3102 | - | 5e-33 | 37.07% (232) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0315 | fabG2 | 1e-32 | 37.72% (228) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_4157 | - | 4e-34 | 38.72% (235) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2709|M.avium_104 MP------------------SRRVLITGASRGIGRAVADRLAEGGHEPIG
MSMEG_0831|M.smegmatis_MC2_155 MT------------------SRRVLISGASKGIGRALADRLAADGHQPVG
Mflv_2501|M.gilvum_PYR-GCK MK--------------------NAVVTGGASGIGAAVVERLRADGLQVAT
Mvan_4157|M.vanbaalenii_PYR-1 MK--------------------NAVVTGGASGIGAAIAERLRADGMRVAT
TH_3102|M.thermoresistible__bu LK--------------------NAVVTGGGSGIGQAVAARLRADGYHVAT
MMAR_4715|M.marinum_M MK--------------------TAVVTGGASGIGLAIARRLRADGIDVAT
MUL_0315|M.ulcerans_Agy99 MRPDSSPS----------WCTITSVVTGGASGIGLAIARRLSADGTDVAT
Mb1519|M.bovis_AF2122/97 MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV
Rv1483|M.tuberculosis_H37Rv MTATATEG------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKVAV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MAB_0952|M.abscessus_ATCC_1997 MVVESAEPAER--KVMFDLSARSVLVTGGTKGIGRGIATVFARAGANVAV
: :::*. *** .:. : *
MAV_2709|M.avium_104 LARSAP------------EDFPGEFYEVDLADPYATAATLDKIVGHA-AV
MSMEG_0831|M.smegmatis_MC2_155 LARTPT------------PDFPGKLFQVDLSDRAATDDALAAVLADG-PI
Mflv_2501|M.gilvum_PYR-GCK IDLNP--------------GDAKFSYAADVTDRSAVDAALDEIRAELGPV
Mvan_4157|M.vanbaalenii_PYR-1 IDLNP--------------GDEKFSYAADVTDRAAVDAVLSEIHTELGPV
TH_3102|M.thermoresistible__bu IDLKP--------------GDDEFSHAADVTDRAQVDAAFDAIRTQLGPV
MMAR_4715|M.marinum_M LDLKT--------------PDGELAFSADVTNRSQVDAALTAIRQRLGPV
MUL_0315|M.ulcerans_Agy99 LDLKT--------------PDGGLAFSADVTNRSQVDAALAAIRQRLGPV
Mb1519|M.bovis_AF2122/97 THRGSG------------APKGLFGVECDVTDSDAVDRAFTAVEEHQGPV
Rv1483|M.tuberculosis_H37Rv THRGSG------------APKGLFGVECDVTDSDAVDRAFTAVEEHQGPV
MLBr_01807|M.leprae_Br4923 THRASV------------VPDWFFGVECDVTDNDAIGAAFKAVEEHQGPV
MAB_0952|M.abscessus_ATCC_1997 AARSPRELSSVTAELGELGAGNVIGVRLDVSDPGSCADAARTVVDAFGAL
. *::: . : .:
MAV_2709|M.avium_104 HAVVNNVGFARFGRLGSIELDHLFDTYDLNVRAAVQVVQAALPGMLDAEW
MSMEG_0831|M.smegmatis_MC2_155 EAVVNNVAGARFARIGEIDLDDLFSTYDMTMRIAVQVTQAVLPGMLDAGW
Mflv_2501|M.gilvum_PYR-GCK TVLVNAAGLDRFKKFLDLSFEEWQKVVDVNLNGVFHCTQAVLPDMIEAGW
Mvan_4157|M.vanbaalenii_PYR-1 TVLVNAAGLDRFKKFLDLTFDEWQKVVDVNLNGVFHCTQAVLPDMIEAGW
TH_3102|M.thermoresistible__bu TILVNAAGLDLFRRFTDISFEDWERVINVNLHGVFHCIQAVLPDMIEAGW
MMAR_4715|M.marinum_M TILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGW
MUL_0315|M.ulcerans_Agy99 TILVNAAGLDGFKRFSNITFEDWQRVIDVNLNGVFHTIQAVLPDMVAAGW
Mb1519|M.bovis_AF2122/97 EVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKF
Rv1483|M.tuberculosis_H37Rv EVLVSNAGLSADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKF
MLBr_01807|M.leprae_Br4923 EVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRF
MAB_0952|M.abscessus_ATCC_1997 DVVCANAGIFPEARLDTMTPEQLSEVLDVNVKGTVYTVQACLAPLTASGR
: .. : : :. . : .: .. : :
MAV_2709|M.avium_104 GRIVNVTSL-TTL-GTPERTPYAAAKAALEACTRIWAGELASAGITVNAV
MSMEG_0831|M.smegmatis_MC2_155 GRVVNVTSL-TTQ-GTPLRTPYAAAKAALETATKTWAGELATSGITVNAV
Mflv_2501|M.gilvum_PYR-GCK GRIVNISSS-STHSGQPYMSPYVAAKSAVNGLTKSLALEYGPAGITVNAV
Mvan_4157|M.vanbaalenii_PYR-1 GRIVNISSS-STHSGQPYMSPYVAAKSAVNGLTKSLALEYGPDGITVNAV
TH_3102|M.thermoresistible__bu GRIVNISSS-STHSGAPYMAPYVAAKSGVNGLTKTLALEYGPAGITVNAV
MMAR_4715|M.marinum_M GRIVNISSS-STHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAV
MUL_0315|M.ulcerans_Agy99 GRIVNISSS-STHSGTPYMTHYVAAKSAVNGLTKALALEYGPSGITVNAV
Mb1519|M.bovis_AF2122/97 GRMIFIGSV-SGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVV
Rv1483|M.tuberculosis_H37Rv GRMIFIGSV-SGSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVV
MLBr_01807|M.leprae_Br4923 GRYIFMGSV-VGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVV
MAB_0952|M.abscessus_ATCC_1997 GRVILTSSITGPVTGYPGWSHYGASKAAQLGFMRTAAIELAPRGVTVNAI
** : * * : * *:*:. : * * . .:*.*.:
MAV_2709|M.avium_104 APGPTETDMYRERSPVGS-EREARFLQSIPLHRVARPREIAHAICFLLDE
MSMEG_0831|M.smegmatis_MC2_155 APGPTETEMYRERSPQGS-ELERRFLENIPMRRVGQPREIAHVIASLLHD
Mflv_2501|M.gilvum_PYR-GCK PPGFIDTPMLRKAEQRGFLGDTEQQIQQTPVRRMGRPEDIAAACAFFISE
Mvan_4157|M.vanbaalenii_PYR-1 PPGFIDTPMLRKAEQRGFLGDTQKQIEQTPVRRMGRPEDIAAACSFLISE
TH_3102|M.thermoresistible__bu PPGFIDTPMLRAAAAKGYLGDIDKTIEATPVRRMGKPEDIAAACAFLISE
MMAR_4715|M.marinum_M PPGFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLVSE
MUL_0315|M.ulcerans_Agy99 PPGFIDTPMLRNAAAQGHLGDIEQNIARTPVRRIGKPEDIAAACAFLVSE
Mb1519|M.bovis_AF2122/97 APGYIDTDMTRALDER----IQQGALQFIPAKRVGTPAEVAGVVSFLASE
Rv1483|M.tuberculosis_H37Rv APGYIDTDMTRALDER----IQQGALQFIPAKRVGTPAEVAGVVSFLASE
MLBr_01807|M.leprae_Br4923 APGFIDTEMTRAMDSK----YQEAALQAIPLGRIGAVEEIAGAVSFLASE
MAB_0952|M.abscessus_ATCC_1997 LPGNILTEGLVDMGEE----YISGMARSIPMGMLGSPVDIGHLAAFLATD
** * * :. ::. . : :
MAV_2709|M.avium_104 DAGYITGQILRVDGGGSIAA-------
MSMEG_0831|M.smegmatis_MC2_155 DAGYITGQIVRVDGGGSVSGAW-----
Mflv_2501|M.gilvum_PYR-GCK EAGYITGQILGVNGGRNT---------
Mvan_4157|M.vanbaalenii_PYR-1 EAGYITGQILGVNGGRNT---------
TH_3102|M.thermoresistible__bu EAGYITGQILGVNGGRNT---------
MMAR_4715|M.marinum_M EAGYITGQILGVNGGRNT---------
MUL_0315|M.ulcerans_Agy99 EAGYITGQILGVNGGRNT---------
Mb1519|M.bovis_AF2122/97 DASYISGAVIPVDGGMGMGH-------
Rv1483|M.tuberculosis_H37Rv DASYISGAVIPVDGGMGMGH-------
MLBr_01807|M.leprae_Br4923 DAGYISGAVIPVDGGLGMGH-------
MAB_0952|M.abscessus_ATCC_1997 EAGYITGQAIVVDGGQVLPESPDAVNP
:*.**:* : *:**