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VTGGPFDGKAVLTGAGKSQVGRRLGRTGLDLTLEAVLRAIADAGLSVDDVDGIASYPGPGVPDAGFSGAT VQEVRNALGLRTRWYVSAMETAGQIGPAIEACMAVSLGLANHVVVYRSVWESTAAQQAGGGRASVLFGGG ELPPHLEWTAPFGALSAANWLAMPAQRYMHDFGLTREHLGRIAINARTNAGLNPDAVYREPMTMDDYLGA RMISEPLCLYDCDVPCDGATAVIVSRRDAANGLPRHPLTVESVGPGMFERATWDQRGDITTMAAHDSAAT LWEHTTLTPADVDMAQLYDGFSFLTVMWLEAMGFCEHGKVGEFVGDGSSIALDSSLPINTSGGQLSGGRL HGMGFLHEACVQLWGEGGDRQAPRTPEVVAVGVGGGPVAGSMLLSSR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2586 | - | - | 100% (397) | DitF protein |
| M. avium 104 | MAV_1865 | - | 0.0 | 90.43% (397) | DitF protein |
| M. avium 104 | MAV_0919 | - | e-100 | 49.75% (394) | hypothetical protein MAV_0919 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3570c | ltp2 | 6e-46 | 32.66% (398) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_2483 | - | 4e-98 | 49.49% (394) | hypothetical protein Mflv_2483 |
| M. tuberculosis H37Rv | Rv3540c | ltp2 | 6e-46 | 32.66% (398) | lipid-transfer protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0618 | - | 1e-48 | 33.09% (405) | lipid-transfer protein |
| M. marinum M | MMAR_4731 | - | 2e-94 | 48.48% (394) | 3-ketoacyl-CoA thiolase |
| M. smegmatis MC2 155 | MSMEG_4814 | - | 8e-99 | 47.88% (401) | hypothetical protein MSMEG_4814 |
| M. thermoresistible (build 8) | TH_4141 | - | 0.0 | 88.58% (394) | PUTATIVE DitF protein |
| M. ulcerans Agy99 | MUL_3406 | - | 4e-82 | 46.68% (377) | acetyl-CoA acetyltransferase |
| M. vanbaalenii PYR-1 | Mvan_4171 | - | 3e-99 | 49.49% (394) | hypothetical protein Mvan_4171 |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2586|M.avium_104 --------------------------------------------------
TH_4141|M.thermoresistible__bu --------------------------------------------------
MUL_3406|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK MSRLP---LPLLTFDNEFFWTSGADGVLRIQECGDCKSLIHPPQPVCRYC
Mvan_4171|M.vanbaalenii_PYR-1 MSRLP---LPQLTFDNEFFWKSGADGVLRIQECGDCKALIHPPQPVCRYC
MMAR_4731|M.marinum_M MSAAPGRPLPLITDENEFFWTSGADGKLRLQECAACASLIHPPAPVCRYC
MSMEG_4814|M.smegmatis_MC2_155 MSQIPGRPLPTVTALNEYFWTAGRDGVLRIQECRSCDALIHPPQPICRYC
Mb3570c|M.bovis_AF2122/97 --------------------------------------------------
Rv3540c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0618|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2586|M.avium_104 --------------------------------------------------
TH_4141|M.thermoresistible__bu --------------------------------------------------
MUL_3406|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK HSHNMGPREVSGRAVLSAFTVNHRFSIPGLEAPYVVAQVAIEEDPRVRLT
Mvan_4171|M.vanbaalenii_PYR-1 HSHNMGPREVSGRAVLSAFTVNHRFSIPGLQAPYVVAQVAIEEDPRVRLT
MMAR_4731|M.marinum_M RSRDMGVRTVSGAATLTGFTVNHRFSLPGLPAPYVIAQVAIAEDPRVRLT
MSMEG_4814|M.smegmatis_MC2_155 RSHDLGVRDVSGRATLAGFTVNERFGFPDMPPPYVVAEVAIVEDPRVRLT
Mb3570c|M.bovis_AF2122/97 --------------------------------------------------
Rv3540c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0618|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2586|M.avium_104 --------------------------------------------------
TH_4141|M.thermoresistible__bu --------------------------------------------------
MUL_3406|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2483|M.gilvum_PYR-GCK TNIVDCDPDELELGRVVEVVFEQNEDVWLPLFRPTAEPETAALPDDEIAP
Mvan_4171|M.vanbaalenii_PYR-1 TNIIDCDPDELELGRVVEVVFEENDDVWLPLFRPTAETETAPLPEDEIAP
MMAR_4731|M.marinum_M TNIVECDPDRLELGQTVEVVFERIEDVWLPLFRPRTDAQPRPLPVDEIAP
MSMEG_4814|M.smegmatis_MC2_155 TNIVDCDPQSLELGQPVEVSFQHIDDVWLPVFTPSADTTPTPAPVEDIAP
Mb3570c|M.bovis_AF2122/97 --------------------------------------------------
Rv3540c|M.tuberculosis_H37Rv --------------------------------------------------
MAB_0618|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2586|M.avium_104 ----------MTGGPFDGKAVLTGAGKSQVGRRLGRTGLDLTLEAVLRAI
TH_4141|M.thermoresistible__bu ----------MSRGPFDGKAVLTGAGKSQVGRRLGRTGLDLTLEAVLRAI
MUL_3406|M.ulcerans_Agy99 ------------------------------------------MEAVRAAV
Mflv_2483|M.gilvum_PYR-GCK QEFPKFVRPMLTTEKFEDAAAITGIGASKMGRRLMVSPLSLTVEACEKAI
Mvan_4171|M.vanbaalenii_PYR-1 QDFGKFVRPMLTTEKFEDAAAITGIGASRMGRRLMVSPLSLTVEACEAAI
MMAR_4731|M.marinum_M QRFGEHVRPMLTTQKFEDKVALTGIGMSTIGRRLMVAPLSLTVDACEAAV
MSMEG_4814|M.smegmatis_MC2_155 QDIGKFVRPMLTEDKFEDHSAITGIGMSRIGRRLMVPPLSLTIEAAEQAV
Mb3570c|M.bovis_AF2122/97 --------------MLSGQAAIVGIGATDFSKNSGRSELRLAAEAVLDAL
Rv3540c|M.tuberculosis_H37Rv --------------MLSGQAAIVGIGATDFSKNSGRSELRLAAEAVLDAL
MAB_0618|M.abscessus_ATCC_1997 ------------MTGLSGRSAIAGIGATDFSKKSGRSELRLAAEAVLDAL
:* *:
MAV_2586|M.avium_104 ADAGLSVDDVDGIASYPGPGVPDAGFSGATVQEVRNALGLRTRWYVSAME
TH_4141|M.thermoresistible__bu ADAGLDVDDIDGIASYPGPGVPDPGFSGAGIHDVRNALGLRSRWYISSME
MUL_3406|M.ulcerans_Agy99 ADAGLTPADVDGIATLG----------DTPAADVNAELQIDAPDCGTGFG
Mflv_2483|M.gilvum_PYR-GCK ADAGLTLADIDGLSTYPAMDAMG--MGEGGCTVLEGALGIRPTWINGGMD
Mvan_4171|M.vanbaalenii_PYR-1 ADAGLTLADIDGLSTYPAMDAMG--MGEGGVTALEGALGIRPTWINGGMD
MMAR_4731|M.marinum_M ADAGLTFDDIDGLSTYPGGGNLGG-FGEGGVTALEAALGIRPVWHNGGIE
MSMEG_4814|M.smegmatis_MC2_155 ADAGLTFDDIDGLSTYPGLDIAG--MGEGGVSVLEGALGLRPTWINGGMD
Mb3570c|M.bovis_AF2122/97 ADAGLSPTDVDGLTTFT--------MDTNTEIAVARAAGIGELTFFSKIH
Rv3540c|M.tuberculosis_H37Rv ADAGLSPTDVDGLTTFT--------MDTNTEIAVARAAGIGELTFFSKIH
MAB_0618|M.abscessus_ATCC_1997 DDAGLSPSDVDGLVTFT--------MDSNLETAVARATGIGELKFFSQIG
**** *:**: : : : :
MAV_2586|M.avium_104 TAG--QIGPAIEACMAVSLGLANHVVVYRSVWES--TAAQQ----AGGGR
TH_4141|M.thermoresistible__bu TAG--QIGPVMEACMAVSLGLANHVVVFRSVWES--TAAQQ----GGGGR
MUL_3406|M.ulcerans_Agy99 TGG--LLSPVMSACRAVAERRARHVIVYRTIQMLGGTVALQPEQDAPAPP
Mflv_2483|M.gilvum_PYR-GCK TFG--PGGSLIAAVMAVATGMARHVLCFRTLWEA---------------T
Mvan_4171|M.vanbaalenii_PYR-1 TFG--PGGSVIAAVMAVATGMARHVLCFRTLWEA---------------T
MMAR_4731|M.marinum_M TFG--PGGSVIAAMLAVAGGLARHVLCFRTLWEA---------------T
MSMEG_4814|M.smegmatis_MC2_155 TFG--PGGSVIAAMMAISAGLARHVLCFRTLWEA---------------T
Mb3570c|M.bovis_AF2122/97 YGGGAACATVQHAAMAVATGVADVVVAYRAFNER------------SGMR
Rv3540c|M.tuberculosis_H37Rv YGGGAACATVQHAAMAVATGVADVVVAYRAFNER------------SGMR
MAB_0618|M.abscessus_ATCC_1997 YGGGAAAATVQQAALAVAAGVAEVVVAYRAFNER------------SEFR
* .. * *:: * *: :*:.
MAV_2586|M.avium_104 ASVLFGGGELPP--------HLEWTAPFGALSAANWLAMPAQRYMHDFGL
TH_4141|M.thermoresistible__bu ASVLFSGGKLPP--------HLEWVAPFGALSAANWLAMPAQRYMQEYGL
MUL_3406|M.ulcerans_Agy99 LARMFDVAEGAPRPAVGPMDDITDLIAAHAYSAANWLALNCRRHMELYGT
Mflv_2483|M.gilvum_PYR-GCK FNQLMKEGKASP---PGGARVNSWQAPFGATSAAHTLALNAQRHFHRYGT
Mvan_4171|M.vanbaalenii_PYR-1 FNQLMKEGRVSP---PGGTRVNSWQAPFGATSAAHTLALNAQRHFHRYGT
MMAR_4731|M.marinum_M YNELMKRGKIAP---PGG-RTTSWQYPFGATSAAHTLAINAQRHFHRYGT
MSMEG_4814|M.smegmatis_MC2_155 FGQLVKEGKMSP---PMSARTNSWQQPYGATSAAHTLAQNAGRHFHRYGT
Mb3570c|M.bovis_AF2122/97 FGQVQTRLTENAD---STGVDNSFSYPHGLSTPAAQVAMIARRYMHLSGA
Rv3540c|M.tuberculosis_H37Rv FGQVQTRLTENAD---STGVDNSFSYPHGLSTPAAQVAMIARRYMHLSGA
MAB_0618|M.abscessus_ATCC_1997 FGQVMTGLSSTAD---SRGVEYSWSYPHGLSTPAASVAMIARRYMHEYGA
: . . :.* :* . *::. *
MAV_2586|M.avium_104 TREHLGRIAINARTNAGLNPDAVYR-EPMTMDDYLGARMISEPLCLYDCD
TH_4141|M.thermoresistible__bu TREQLGAIAINARRNAGLNPDAIYR-EPMTMDDYLGARMISEPLCLYDCD
MUL_3406|M.ulcerans_Agy99 TREQLGWVALNGRRNAALNPLAVYR-EPMTMADYLGARPVSTPLGLLDCD
Mflv_2483|M.gilvum_PYR-GCK TKETLGWIALNQRANAALNPTAIYR-DPMTMQDYLNARPITTPFGLYDCD
Mvan_4171|M.vanbaalenii_PYR-1 TKETLGWIALNQRANAALNPTAIYR-DPMTMDDYLNARPITTPFGLYDCD
MMAR_4731|M.marinum_M TKETLGWIALNQRANAELNPTAVYR-SPMTMDDYLNARPITTPFGLFDCD
MSMEG_4814|M.smegmatis_MC2_155 TRETLGWIALNQRANAALNPTAIYR-EPLTMEDYLSARTITTPFGLYDCD
Mb3570c|M.bovis_AF2122/97 TSRDFGAVSVADRKHAANNPKAYFYGKPITIEDHQNSRWIAEPLRLLDCC
Rv3540c|M.tuberculosis_H37Rv TSRDFGAVSVADRKHAANNPKAYFYGKPITIEDHQNSRWIAEPLRLLDCC
MAB_0618|M.abscessus_ATCC_1997 TSADFGAVSVADRKHAATNPKAFFYGKPITIEDHQNSRMIADPVRLLDCC
* :* ::: * :* ** * : .*:*: *: .:* :: *. * **
MAV_2586|M.avium_104 VPCDGATAVIVSRRDAANGLPRHPLTVESVGPGMFER----ATWDQRGDI
TH_4141|M.thermoresistible__bu IPCDGATAVIVSRRDAAKGLPRHPLTVGSVGPGMFER----ATWDQRSDL
MUL_3406|M.ulcerans_Agy99 VPIDGCVAVLVSTAEYARDCPPRAVRVEAIG-GSDGS----GGWFHRADY
Mflv_2483|M.gilvum_PYR-GCK VPCDGAVAVIVSAVDAAADAPKPPVFFEAVGTQIIER----TDWDQTTLT
Mvan_4171|M.vanbaalenii_PYR-1 VPCDGAVAVVVSAVDAAVDLPKPPVYFEAVGTQIIER----TDWDQTTLT
MMAR_4731|M.marinum_M VPCDAAIAVIVSAVDAARDLAKPPVLVEAVGTQIIER----IDWDQSTLT
MSMEG_4814|M.smegmatis_MC2_155 VPCDGAVAVIVSAVDAARDLPRPPIRFEAVGTQIIER----LDWDQTTLT
Mb3570c|M.bovis_AF2122/97 QETDGAVAIVVTSAARARDLKQRPVVIEAAAQGCSPDQYTMVSYYRPELD
Rv3540c|M.tuberculosis_H37Rv QETDGAVAIVVTSAARARDLKQRPVVIEAAAQGCSPDQYTMVSYYRPELD
MAB_0618|M.abscessus_ATCC_1997 QESDGGVAIVVTTPERAKDLKNRPVIIEAAAQGSGEDQFTMYSYYRDELG
*. *::*: * . .: . : . : :
MAV_2586|M.avium_104 TTMAAHDSAATLWEHTTLTPADVDMAQLYDGFSFLTVMWLEAMGFCEHGK
TH_4141|M.thermoresistible__bu TTMAAHDSAATLWQNTTLTPKDVDMAQIYDGFSFLTVMWLEALGFCEHGR
MUL_3406|M.ulcerans_Agy99 PKMAMSDAAAQMWSRTALKPADLEVAQLYDGFTFLTLAWLEALGICADGE
Mflv_2483|M.gilvum_PYR-GCK HEPQVLGQAAHLWTRTSLRPDDVDVAELYDGFTFNCLSWLEALGFCGIGE
Mvan_4171|M.vanbaalenii_PYR-1 HEPQVLGQAAHLWTRTSLRPADVDVAELYDGFTFNCLSWLEALGFCGIGE
MMAR_4731|M.marinum_M HEPQVLGQAAHVWTRTTLRPADVDVAELYDGFTMNCLSWIEALGFCGIGE
MSMEG_4814|M.smegmatis_MC2_155 HEPQVLGQSAHMWSRTSLRPSDVDVAELYDGFTFNCLSWLEGLGFCGIGE
Mb3570c|M.bovis_AF2122/97 GLPEMGLVGRQLWAQSGLTPADVQTAVLYDHFTPFTLIQLEELGFCGKGE
Rv3540c|M.tuberculosis_H37Rv GLPEMGLVGRQLWAQSGLTPADVQTAVLYDHFTPFTLIQLEELGFCGKGE
MAB_0618|M.abscessus_ATCC_1997 -LPEMGLVGRQLWDQSGLTPNDIQTAILYDHFTPYTLLQLEELGFCGKGE
. :* .: * * *:: * :** *: : :* :*:* *.
MAV_2586|M.avium_104 VGEFVGDGSSIALDSSLPINTSGGQLSGGRLHGMGFLHEACVQLWGEGGD
TH_4141|M.thermoresistible__bu VGEFIEGGQRIALDGDLPINTSGGQLSAGRLHGMGFLHEACVQMWGEGGD
MUL_3406|M.ulcerans_Agy99 AGPFVEGGARIARDGKLPLNTYGGQLSARRMHGYWALHEGCLQLRGDAGQ
Mflv_2483|M.gilvum_PYR-GCK SKDFLDGGHAIARDGVIPLNTHGGQLSHGRTHGMGLVHEAVSQLRGEAGE
Mvan_4171|M.vanbaalenii_PYR-1 AKDFLDGGKAIARDGVIPLNTHGGQLSHGRTHGMGLIHEAVSQLRGEAGE
MMAR_4731|M.marinum_M AKEFLDGGKNIARDGLIPLNTHGGQLSHGRTHGMGLLHEAVTQLRGEADA
MSMEG_4814|M.smegmatis_MC2_155 AKDFLDGGRNIARDGIIPLNTHGGQLSHGRTHGMGLIHEAVTQLRGEAGE
Mb3570c|M.bovis_AF2122/97 AKDFIADG-AIEVGGRLPINTHGGQLGEAYIHGMNGIAEGVRQLRG-TSV
Rv3540c|M.tuberculosis_H37Rv AKDFIADG-AIEVGGRLPINTHGGQLGEAYIHGMNGIAEGVRQLRG-TSV
MAB_0618|M.abscessus_ATCC_1997 AKDFIANG-AIELGGKLPINTHGGQLGEAYIHGMNGIAEGVRQLRG-TSV
*: .* * .. :*:** ****. ** : *. *: * .
MAV_2586|M.avium_104 RQAPRTPEVVAVGVGGGPVAGSMLLSSR-
TH_4141|M.thermoresistible__bu RQAPKTPEVVAVGVGGGPVAGSMLLSSR-
MUL_3406|M.ulcerans_Agy99 RQVPRRPEVGVVSVGGGPIAGCMLLTC--
Mflv_2483|M.gilvum_PYR-GCK RQVAD-ARVAVVSSGGLTPSGVMLLRTGA
Mvan_4171|M.vanbaalenii_PYR-1 RQVDG-ARVAVVSSGGLTPSGALLLRTAT
MMAR_4731|M.marinum_M RQVAG-ARVGVVSSGGLTPSGVILLRADT
MSMEG_4814|M.smegmatis_MC2_155 RQVED-ARVAVASSGGLTPSGVLLLRRDD
Mb3570c|M.bovis_AF2122/97 NPVAGVEHVLVTAGTGVPTSGLILG----
Rv3540c|M.tuberculosis_H37Rv NPVAGVEHVLVTAGTGVPTSGLILG----
MAB_0618|M.abscessus_ATCC_1997 NQVPNVEHVLVTAGTGVPTSGLILG----
. . .* ... * . :* :*