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SSTPDIAIIGVGLHPFGRYEDRSALEMGAVAISRALRDAGVAWSDVGSLYAGSLEVANPEAVTGLAGMTG LPARATLSGCATGNSLLTLAARDVQLGEADIAVGVGLDKHPRGAFGADPSVSGLPQWYGDQGMFLTTHYF GTKIMRYMHDHGITEETLARVAAKNFDNGALAPHAWRRKPMSVDAILSSPVVNAPLRQYMYCNPNEGAAA VVVCRADKAKQYTDSPIYLRSTALRSRREGAYELLRTSIELPIVPGTTAEAARAAYELAGIGPEDVDVAQ LQDTDSGSEIIHMAETGLCKDGEQEALLADGATKIGGRLPINTDGGLLANGEPVGASGLRQVYELVQQLR GTAGDRQVPNDPQVGLAQLYGAPGTAAVAILSK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2573 | - | - | 100% (384) | lipid-transfer protein |
| M. avium 104 | MAV_1842 | - | 0.0 | 91.93% (384) | lipid-transfer protein |
| M. avium 104 | MAV_0989 | - | e-138 | 62.11% (380) | putative thiolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1653c | - | 6e-52 | 36.05% (405) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_2519 | - | 1e-139 | 62.57% (382) | thiolase |
| M. tuberculosis H37Rv | Rv1627c | - | 6e-52 | 36.05% (405) | lipid-transfer protein |
| M. leprae Br4923 | MLBr_02158 | - | 2e-12 | 37.29% (118) | hypothetical protein MLBr_02158 |
| M. abscessus ATCC 19977 | MAB_2619 | - | 6e-51 | 35.54% (408) | lipid-transfer protein |
| M. marinum M | MMAR_2430 | - | 2e-48 | 35.06% (405) | nonspecific lipid-transfer protein |
| M. smegmatis MC2 155 | MSMEG_2236 | - | 1e-137 | 60.16% (379) | putative thiolase |
| M. thermoresistible (build 8) | TH_3921 | - | 0.0 | 89.82% (383) | PUTATIVE lipid-transfer protein |
| M. ulcerans Agy99 | MUL_4955 | ltp1_1 | 3e-48 | 31.82% (418) | lipid-transfer protein Ltp1_1 |
| M. vanbaalenii PYR-1 | Mvan_4139 | - | 1e-137 | 61.64% (378) | thiolase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2573|M.avium_104 -MSS----TPDIAIIGVGLHPFGRYEDRSALEMGAVAISRALRDAGVAWS
TH_3921|M.thermoresistible__bu MSSS----NADIAIIGVGIHPFGRYENRSALEMGAVAIGRALRDAGVGWT
Mflv_2519|M.gilvum_PYR-GCK MTSS----ANDVAIIGVGLHPFGRFD-KTAMEMGAEAIQSALTDAGVDWK
Mvan_4139|M.vanbaalenii_PYR-1 MTNSSPNAAGEVAIIGVGLHPFGRFD-KTAMQMGAEAIQSALTDAGVEWK
MSMEG_2236|M.smegmatis_MC2_155 -------MSHDVAIIGVGIHPFGRFEGKTAMQMGVDAIFAAVADAGVDWK
MLBr_02158|M.leprae_Br4923 --------------------------------------------------
MUL_4955|M.ulcerans_Agy99 -----MSASDEIWILGIRMTKFGKHPDLDTVDLAAQAAMSALDDAGVSMA
Mb1653c|M.bovis_AF2122/97 --MRMS-APEPVYILGAGMHPWGKWG-NDFTEYGVVAARAALRDAGVDWR
Rv1627c|M.tuberculosis_H37Rv --MRMS-APEPVYILGAGMHPWGKWG-NDFTEYGVVAARAALRDAGVDWR
MMAR_2430|M.marinum_M ----MS-APEPLYILGAGMHPWGKWG-NDFTEYGVAAARAALREAGLEWR
MAB_2619|M.abscessus_ATCC_1997 ----MSRTPDPVYILGAGMHPWGKWG-RDFTEYGVAAARTALQDAELDWR
MAV_2573|M.avium_104 DVGSLYAGSLEVANP------EAVTGLAGMTGLPARATLSGCATGNSLLT
TH_3921|M.thermoresistible__bu EVGSLYAGSLEVANP------EAVTGLVGMTGIPARATLSGCATGNSLLT
Mflv_2519|M.gilvum_PYR-GCK DIQFGFGGSYEVSNP------DAVTRLVGLTGITFTNVFNACATAASAIQ
Mvan_4139|M.vanbaalenii_PYR-1 DIQFGFGGSYEVSNP------DAVTRLVGLTGITFTNVFNACATAASAIQ
MSMEG_2236|M.smegmatis_MC2_155 DIGAATGGSWTVANP------DAIVGMVGLSGIPFTNVFNACATAASATK
MLBr_02158|M.leprae_Br4923 --------------------------------------------------
MUL_4955|M.ulcerans_Agy99 DIGVLAAGNLMAANAG---IGQQLQKQIGQTGIPVYNVANACATGATALR
Mb1653c|M.bovis_AF2122/97 HVQLVAGADTIRNGYPGFVAGATFAQKLGWTGVPVSSSYAACASGSQALQ
Rv1627c|M.tuberculosis_H37Rv HVQLVAGADTIRNGYPGFVAGATFAQKLGWTGVPVSSSYAACASGSQALQ
MMAR_2430|M.marinum_M QIQLVAGADTIRNGYPGFVAGATFAQKLGWNGVPVSSSYAACASGSQALQ
MAB_2619|M.abscessus_ATCC_1997 QIQFVAGADTIRNGYPGFIAGSTFAQKLGWNGVPISSTYAACASGSQALQ
MAV_2573|M.avium_104 LAARDVQLGEADIAVGVGLDKHPRG--------------AFGADPSVSGL
TH_3921|M.thermoresistible__bu LAARDVQLGEVDIAVGVGLDKHPRG--------------AFGADPSVAGL
Mflv_2519|M.gilvum_PYR-GCK QTADTIRLGKYDIGIAIGLDKHPRG--------------AFTDDPAKLAL
Mvan_4139|M.vanbaalenii_PYR-1 QTADTIRLGKYDIGIAIGLDKHPRG--------------AFTDDPAKLAL
MSMEG_2236|M.smegmatis_MC2_155 VCADGIRLGDYDIGIAVGLDKHPRG--------------AFTEDPALVGM
MLBr_02158|M.leprae_Br4923 --------------------------------------------------
MUL_4955|M.ulcerans_Agy99 TAIMAVKAGEVDYGMAVGVEKLSGAGLLGGGGKKKSDADVWTPAGRYGAV
Mb1653c|M.bovis_AF2122/97 SARAQILAGFCDVALVIGADTTPKG-------------FFAPVGGERKGD
Rv1627c|M.tuberculosis_H37Rv SARAQILAGFCDVALVIGADTTPKG-------------FFAPVGGERKGD
MMAR_2430|M.marinum_M SARAQILAGFCDVALVVGADTTPKG-------------FFAPVGGERKND
MAB_2619|M.abscessus_ATCC_1997 SARAQILAGFCDVALVIGADTTPKG-------------FFAPVGGERKAD
MAV_2573|M.avium_104 PQWYGDQGMFLTTHYFGTKIMRYMHDHG-ITEETLARVAAKNFDNGALAP
TH_3921|M.thermoresistible__bu PQWYGDQGMFLTTHYFGTKIMRYMHDWG-ISEETLARIAVKNFSNGALTD
Mflv_2519|M.gilvum_PYR-GCK PQWYANNGQFVTTKFFGMKANHYLHKHN-ISEETLARVANKNFRNGVINP
Mvan_4139|M.vanbaalenii_PYR-1 PQWYAENGQFVTTKFFGMKANHYIHKHN-ISEETLARVANKNFRNGVLNP
MSMEG_2236|M.smegmatis_MC2_155 PKWYAENGQYLTTQFFGMKANRYLHDHN-ISRRTLARVAAKNFRNGALNP
MLBr_02158|M.leprae_Br4923 ----------------------------------MCSVASRFLR------
MUL_4955|M.ulcerans_Agy99 APVDGRIGTETMPGVFAQIGTEYGHKYGGTSFELFAKISEKNHAHSTLNP
Mb1653c|M.bovis_AF2122/97 PDWQRFHLIGATNTVYFALLARRRMDLYGATVEDFAQVKVKNSRHGLDNP
Rv1627c|M.tuberculosis_H37Rv PDWQRFHLIGATNTVYFALLARRRMDLYGATVEDFAQVKVKNSRHGLDNP
MMAR_2430|M.marinum_M PDWQRFHLIGATNPVYFALLARRRMDLYGATLEDFAQVKVKNSRHGLQNP
MAB_2619|M.abscessus_ATCC_1997 PDWQRFHLIGATNPVYFALLARRRMDLFGATVEDFAQVKVKNSRHGLNNP
:. : :
MAV_2573|M.avium_104 HAWRRKPMSVDAILSSPVVNAPLRQYMYCNPNEGAAAVVVCRADKAKQYT
TH_3921|M.thermoresistible__bu HAWRRNAMSLETVLSSPVVNAPLRQYMYCNPNEGAAAVVICRADVAKRYT
Mflv_2519|M.gilvum_PYR-GCK NAFRRKEISVEEIMASPVLNYPLRQYMFCAPDEGAAAVIMCRADIAHKYT
Mvan_4139|M.vanbaalenii_PYR-1 NAFRRKEISVEEIMASPVLNYPLRQYMFCAPDEGAAAVIMCRGDIAHRFT
MSMEG_2236|M.smegmatis_MC2_155 NAFRRKPISEDDILNSTMLNYPLTQYMFCAPDEGAAAVVMCRADIAHRYT
MLBr_02158|M.leprae_Br4923 -------------------TRSLTQCMFCALNKGAFAVIVCLGDIAHKFT
MUL_4955|M.ulcerans_Agy99 LAAYQKRFTLEQIMNDVMIAYPNTRPMCSANCDGAAAAIVCNGETLKSLS
Mb1653c|M.bovis_AF2122/97 NARYRKENSIDDVLASPVVSDPLRLLDICATSDGAAALIVASKSFTEKHL
Rv1627c|M.tuberculosis_H37Rv NARYRKENSIDDVLASPVVSDPLRLLDICATSDGAAALIVASKSFTEKHL
MMAR_2430|M.marinum_M NARYRKEVSVEDVLASQVVAEPLRLLDICATSDGAAALIVASAKFAREHL
MAB_2619|M.abscessus_ATCC_1997 NARFRKESSVADVLASPVVSDPLRLLDICATSDGAAALIVASADFAKKHL
. . .** * ::. . .
MAV_2573|M.avium_104 DSPIYLRSTALRSRREGAYELLRTSIELPIVPGT-TAEAAR---------
TH_3921|M.thermoresistible__bu DSPIYLRATALRSRQEGAYELLRTSIELPIVPGT-TAEAAK---------
Mflv_2519|M.gilvum_PYR-GCK DKPVYVRASEIRTRTYGAYEVHATSAPLDEDPSP-TVFAAK---------
Mvan_4139|M.vanbaalenii_PYR-1 DKPVFVRASEIRTRTFGAYEVHATSAPLEEDPSP-TVFAAK---------
MSMEG_2236|M.smegmatis_MC2_155 DKPVYLKAVEVRTRRYGAYEVNTTCAPVEEDVAP-TVYAAR---------
MLBr_02158|M.leprae_Br4923 DKTVHVHVTEIRTRRYGAYEVHATFAPLVEDASPKRCTIAK---------
MUL_4955|M.ulcerans_Agy99 AR--QRRRAVKVSASVLTTDPYEPGCQVLPNVNTLTRNAAK---------
Mb1653c|M.bovis_AF2122/97 GSVAGVPSVRAISTVTPKYPQHLPELPDIATDSTAAVPAPERVFKDQILD
Rv1627c|M.tuberculosis_H37Rv GSVAGVPSVRAISTVTPKYPQHLPELPDIATDSTAAVPAPERVFKDQILD
MMAR_2430|M.marinum_M GSLDGVPSVRAVSTVTPRYPQHLPELPDIATDSTAVVPAPERVFKDQILD
MAB_2619|M.abscessus_ATCC_1997 GSVDGVPSVRAVATITPKYPQHLPELPDIATDSTAVVPAPERVFKDQIVD
: . . ..
MAV_2573|M.avium_104 AAYELAGIGPEDVDVAQLQDTDSGS-EIIHMAETGLCKDGEQEALLADGA
TH_3921|M.thermoresistible__bu AAYELAGIGPEDVDVAQLQDTDAGS-EIIHMAETGLCKDGEQEALLREGA
Mflv_2519|M.gilvum_PYR-GCK AAYEAAGIGPEDVDIAQLQDTDAGA-EVIHMAETGLCADGEQEKLLADGA
Mvan_4139|M.vanbaalenii_PYR-1 AAYEAAGIGPEDVDIAQLQDTDAGA-EVIHMAETGLCADGEQEKLLADGA
MSMEG_2236|M.smegmatis_MC2_155 AAFEKAGVAPEDVDVIQLQDTDAGA-EIIHMAECGFCAHGDQEKLLADGA
MLBr_02158|M.leprae_Br4923 AVYRGRQASDLRTSTSPSCRTSVPAPEVIQMDETVLCADGEQEKLASW--
MUL_4955|M.ulcerans_Agy99 TAYEQAGVGPSDLDLVELHDCFATA-ELVHYDNLMLCEQGGAADFFESGA
Mb1653c|M.bovis_AF2122/97 AAYAEAGIGPEDLSLAEVYDLSTAL-ELDWYEHLGLCPKGEAEALLRSGA
Rv1627c|M.tuberculosis_H37Rv AAYAEAGIGPEDLSLAEVYDLSTAL-ELDWYEHLGLCPKGEAEALLRSGA
MMAR_2430|M.marinum_M AAYTEAGIGPEDLSLAEVYDLSTAL-ELDWYEHLGLCPKGEAEALLRSGA
MAB_2619|M.abscessus_ATCC_1997 AAYAEAGIGPEDISLAEVYDLSTAL-ELDWYEHLGLCAKGEGEQLLRSGA
:.: . . *: . :* .* :
MAV_2573|M.avium_104 TKIGGRLPINTDGGLLANGEPVGASGLRQVYELVQQLRGTAGDRQVPNDP
TH_3921|M.thermoresistible__bu TNIGGRLPINTDGGLLANGEPVGASGLRQVYELVHQLRGTAGDRQVPNDP
Mflv_2519|M.gilvum_PYR-GCK TEIHGSIPVNTDGGLIANGEPIGASGLRQVHELVRQLRGEAGDRQVPGAP
Mvan_4139|M.vanbaalenii_PYR-1 TEIHGSIPVNTDGGLIANGEPIGASGLRQVHELVRQLRGQAGDRQVPGQP
MSMEG_2236|M.smegmatis_MC2_155 TEIGGSLPVNTDGGLIANGEPIGASGLRQIHELVRQLRGEAGDRQVPGEP
MLBr_02158|M.leprae_Br4923 --------------------------------------------------
MUL_4955|M.ulcerans_Agy99 PWRHGSTPVNVSGGLQSKGHPIAATGIANVWEICHQLRGEAGDRQIDN-A
Mb1653c|M.bovis_AF2122/97 TTLGGRVPVNPSGGLACFGEAIPAQAIAQVCELTWQLRGQATGRQVAD-A
Rv1627c|M.tuberculosis_H37Rv TTLGGRVPVNPSGGLACFGEAIPAQAIAQVCELTWQLRGQATGRQVAD-A
MMAR_2430|M.marinum_M TTIGGRVPVNPSGGLACFGEAIPAQAIAQVCELNWQLRGQATGRQVEN-A
MAB_2619|M.abscessus_ATCC_1997 TTVGGRVPVNASGGLACFGEAIPAQAIAQVCELTWQLRGQAGDRQVEG-A
MAV_2573|M.avium_104 QVGLAQLYGAPGTAAVAILSK---
TH_3921|M.thermoresistible__bu RVALAQLYGSPGTAAVAILSK---
Mflv_2519|M.gilvum_PYR-GCK RVGLAQVYGAPGTASATILSL---
Mvan_4139|M.vanbaalenii_PYR-1 RVGLAQVYGAPGTASATILSL---
MSMEG_2236|M.smegmatis_MC2_155 KVGFAQLYGAPGTAGATILTR---
MLBr_02158|M.leprae_Br4923 ------------------------
MUL_4955|M.ulcerans_Agy99 KVGLAHVIGLGSACGVHILERSAA
Mb1653c|M.bovis_AF2122/97 KVGVTANQGLFGHGSSVIVAR---
Rv1627c|M.tuberculosis_H37Rv KVGVTANQGLFGHGSSVIVAR---
MMAR_2430|M.marinum_M RVGVTANQGLFGHGSSVIVAR---
MAB_2619|M.abscessus_ATCC_1997 RVGITANQGLFGNGSSVIVAR---