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SSTPDIAIIGVGLHPFGRYEDRSALEMGAVAISRALRDAGVDFSDVGSLYAGSLEVANPEAVTGLVGMTG IPARATLSGCATGNSLLTLAARDVALGEAEIAVGVGLDKHPRGAFGADPSVSGLPQWYGDQGMFLTTHYF GTKIMRYMHDHGITEQALARVAAKNFDNGAKNPNAWRRKPMSEEAILASPIVNAPLRQYMYCNPNEGAAA VVVCRADAAKKYTDTPIYLRSSALRSRREGAYELLRTSIELPIVPGTTAEAAKAAYEIAGIGPEDIDVAQ LQDTDSGSEVIHMAETMLCKDGEQEALLADGATQIGGRLPINTDGGLLANGEPVGASGLRQVFELVHQLR GTAGDRQVPNEPRVALAQLYGAPGTAAVAILSR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1842 | - | - | 100% (384) | lipid-transfer protein |
| M. avium 104 | MAV_2573 | - | 0.0 | 91.93% (384) | lipid-transfer protein |
| M. avium 104 | MAV_0989 | - | e-134 | 61.05% (380) | putative thiolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1653c | - | 1e-50 | 35.31% (405) | lipid-transfer protein |
| M. gilvum PYR-GCK | Mflv_2519 | - | 1e-139 | 63.35% (382) | thiolase |
| M. tuberculosis H37Rv | Rv1627c | - | 1e-50 | 35.31% (405) | lipid-transfer protein |
| M. leprae Br4923 | MLBr_02158 | - | 1e-13 | 38.98% (118) | hypothetical protein MLBr_02158 |
| M. abscessus ATCC 19977 | MAB_2619 | - | 3e-51 | 34.79% (411) | lipid-transfer protein |
| M. marinum M | MMAR_0142 | ltp1_1 | 7e-49 | 32.30% (418) | lipid-transfer protein Ltp1_1 |
| M. smegmatis MC2 155 | MSMEG_2236 | - | 1e-135 | 59.63% (379) | putative thiolase |
| M. thermoresistible (build 8) | TH_3921 | - | 0.0 | 86.95% (383) | PUTATIVE lipid-transfer protein |
| M. ulcerans Agy99 | MUL_4955 | ltp1_1 | 2e-49 | 32.54% (418) | lipid-transfer protein Ltp1_1 |
| M. vanbaalenii PYR-1 | Mvan_4139 | - | 1e-135 | 61.64% (378) | thiolase |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_1842|M.avium_104 -MSS----TPDIAIIGVGLHPFGRYEDRSALEMGAVAISRALRDAGVDFS
TH_3921|M.thermoresistible__bu MSSS----NADIAIIGVGIHPFGRYENRSALEMGAVAIGRALRDAGVGWT
Mflv_2519|M.gilvum_PYR-GCK MTSS----ANDVAIIGVGLHPFGRFD-KTAMEMGAEAIQSALTDAGVDWK
Mvan_4139|M.vanbaalenii_PYR-1 MTNSSPNAAGEVAIIGVGLHPFGRFD-KTAMQMGAEAIQSALTDAGVEWK
MSMEG_2236|M.smegmatis_MC2_155 -------MSHDVAIIGVGIHPFGRFEGKTAMQMGVDAIFAAVADAGVDWK
MLBr_02158|M.leprae_Br4923 --------------------------------------------------
MMAR_0142|M.marinum_M -----MSASDEIWILGIRMTKFGKHPDLDTVDLAAQAAMSALDDAGVSMA
MUL_4955|M.ulcerans_Agy99 -----MSASDEIWILGIRMTKFGKHPDLDTVDLAAQAAMSALDDAGVSMA
Mb1653c|M.bovis_AF2122/97 --MRMS-APEPVYILGAGMHPWGKWG-NDFTEYGVVAARAALRDAGVDWR
Rv1627c|M.tuberculosis_H37Rv --MRMS-APEPVYILGAGMHPWGKWG-NDFTEYGVVAARAALRDAGVDWR
MAB_2619|M.abscessus_ATCC_1997 ----MSRTPDPVYILGAGMHPWGKWG-RDFTEYGVAAARTALQDAELDWR
MAV_1842|M.avium_104 DVGSLYAGSLEVANP------EAVTGLVGMTGIPARATLSGCATGNSLLT
TH_3921|M.thermoresistible__bu EVGSLYAGSLEVANP------EAVTGLVGMTGIPARATLSGCATGNSLLT
Mflv_2519|M.gilvum_PYR-GCK DIQFGFGGSYEVSNP------DAVTRLVGLTGITFTNVFNACATAASAIQ
Mvan_4139|M.vanbaalenii_PYR-1 DIQFGFGGSYEVSNP------DAVTRLVGLTGITFTNVFNACATAASAIQ
MSMEG_2236|M.smegmatis_MC2_155 DIGAATGGSWTVANP------DAIVGMVGLSGIPFTNVFNACATAASATK
MLBr_02158|M.leprae_Br4923 --------------------------------------------------
MMAR_0142|M.marinum_M DIGVLAAGNLMAANAG---IGQQLQKQIGQTGIPVYNVANACATGATALR
MUL_4955|M.ulcerans_Agy99 DIGVLAAGNLMAANAG---IGQQLQKQIGQTGIPVYNVANACATGATALR
Mb1653c|M.bovis_AF2122/97 HVQLVAGADTIRNGYPGFVAGATFAQKLGWTGVPVSSSYAACASGSQALQ
Rv1627c|M.tuberculosis_H37Rv HVQLVAGADTIRNGYPGFVAGATFAQKLGWTGVPVSSSYAACASGSQALQ
MAB_2619|M.abscessus_ATCC_1997 QIQFVAGADTIRNGYPGFIAGSTFAQKLGWNGVPISSTYAACASGSQALQ
MAV_1842|M.avium_104 LAARDVALGEAEIAVGVGLDKHPRG--------------AFGADPSVSGL
TH_3921|M.thermoresistible__bu LAARDVQLGEVDIAVGVGLDKHPRG--------------AFGADPSVAGL
Mflv_2519|M.gilvum_PYR-GCK QTADTIRLGKYDIGIAIGLDKHPRG--------------AFTDDPAKLAL
Mvan_4139|M.vanbaalenii_PYR-1 QTADTIRLGKYDIGIAIGLDKHPRG--------------AFTDDPAKLAL
MSMEG_2236|M.smegmatis_MC2_155 VCADGIRLGDYDIGIAVGLDKHPRG--------------AFTEDPALVGM
MLBr_02158|M.leprae_Br4923 --------------------------------------------------
MMAR_0142|M.marinum_M TAIMAVKAGEVDYGMAVGVEKLSGAGLLGGGGKKKSDADVWTPAGRYGAV
MUL_4955|M.ulcerans_Agy99 TAIMAVKAGEVDYGMAVGVEKLSGAGLLGGGGKKKSDADVWTPAGRYGAV
Mb1653c|M.bovis_AF2122/97 SARAQILAGFCDVALVIGADTTPKG-------------FFAPVGGERKGD
Rv1627c|M.tuberculosis_H37Rv SARAQILAGFCDVALVIGADTTPKG-------------FFAPVGGERKGD
MAB_2619|M.abscessus_ATCC_1997 SARAQILAGFCDVALVIGADTTPKG-------------FFAPVGGERKAD
MAV_1842|M.avium_104 PQWYGDQGMFLTTHYFGTKIMRYMHDHG-ITEQALARVAAKNFDNGAKNP
TH_3921|M.thermoresistible__bu PQWYGDQGMFLTTHYFGTKIMRYMHDWG-ISEETLARIAVKNFSNGALTD
Mflv_2519|M.gilvum_PYR-GCK PQWYANNGQFVTTKFFGMKANHYLHKHN-ISEETLARVANKNFRNGVINP
Mvan_4139|M.vanbaalenii_PYR-1 PQWYAENGQFVTTKFFGMKANHYIHKHN-ISEETLARVANKNFRNGVLNP
MSMEG_2236|M.smegmatis_MC2_155 PKWYAENGQYLTTQFFGMKANRYLHDHN-ISRRTLARVAAKNFRNGALNP
MLBr_02158|M.leprae_Br4923 ----------------------------------MCSVASRFLR------
MMAR_0142|M.marinum_M APVDGRIGTETMPGVFAQIGTEYGHKYGGTSFELFAKISEKNHAHSTLNP
MUL_4955|M.ulcerans_Agy99 APVDGRIGTETMPGVFAQIGTEYGHKYGGTSFELFAKISEKNHAHSTLNP
Mb1653c|M.bovis_AF2122/97 PDWQRFHLIGATNTVYFALLARRRMDLYGATVEDFAQVKVKNSRHGLDNP
Rv1627c|M.tuberculosis_H37Rv PDWQRFHLIGATNTVYFALLARRRMDLYGATVEDFAQVKVKNSRHGLDNP
MAB_2619|M.abscessus_ATCC_1997 PDWQRFHLIGATNPVYFALLARRRMDLFGATVEDFAQVKVKNSRHGLNNP
:. : :
MAV_1842|M.avium_104 NAWRRKPMSEEAILASPIVNAPLRQYMYCNPNEGAAAVVVCRADAAKKYT
TH_3921|M.thermoresistible__bu HAWRRNAMSLETVLSSPVVNAPLRQYMYCNPNEGAAAVVICRADVAKRYT
Mflv_2519|M.gilvum_PYR-GCK NAFRRKEISVEEIMASPVLNYPLRQYMFCAPDEGAAAVIMCRADIAHKYT
Mvan_4139|M.vanbaalenii_PYR-1 NAFRRKEISVEEIMASPVLNYPLRQYMFCAPDEGAAAVIMCRGDIAHRFT
MSMEG_2236|M.smegmatis_MC2_155 NAFRRKPISEDDILNSTMLNYPLTQYMFCAPDEGAAAVVMCRADIAHRYT
MLBr_02158|M.leprae_Br4923 -------------------TRSLTQCMFCALNKGAFAVIVCLGDIAHKFT
MMAR_0142|M.marinum_M LAAYQKRFTLEQIMNDVMIAYPNTRPMCSANCDGAAAAIVCNGETLKSLS
MUL_4955|M.ulcerans_Agy99 LAAYQKRFTLEQIMNDVMIAYPNTRPMCSANCDGAAAAIVCNGETLKSLS
Mb1653c|M.bovis_AF2122/97 NARYRKENSIDDVLASPVVSDPLRLLDICATSDGAAALIVASKSFTEKHL
Rv1627c|M.tuberculosis_H37Rv NARYRKENSIDDVLASPVVSDPLRLLDICATSDGAAALIVASKSFTEKHL
MAB_2619|M.abscessus_ATCC_1997 NARFRKESSVADVLASPVVSDPLRLLDICATSDGAAALIVASADFAKKHL
. . .** * ::. . .
MAV_1842|M.avium_104 DTPIYLRSSALRSRREGAYELLRTSIELPIVPGT-TAEAAK---------
TH_3921|M.thermoresistible__bu DSPIYLRATALRSRQEGAYELLRTSIELPIVPGT-TAEAAK---------
Mflv_2519|M.gilvum_PYR-GCK DKPVYVRASEIRTRTYGAYEVHATSAPLDEDPSP-TVFAAK---------
Mvan_4139|M.vanbaalenii_PYR-1 DKPVFVRASEIRTRTFGAYEVHATSAPLEEDPSP-TVFAAK---------
MSMEG_2236|M.smegmatis_MC2_155 DKPVYLKAVEVRTRRYGAYEVNTTCAPVEEDVAP-TVYAAR---------
MLBr_02158|M.leprae_Br4923 DKTVHVHVTEIRTRRYGAYEVHATFAPLVEDASPKRCTIAK---------
MMAR_0142|M.marinum_M AR--QRRRAVKVSASVLTTDPYEPGCQVLPNVNTLTRNAAK---------
MUL_4955|M.ulcerans_Agy99 AR--QRRRAVKVSASVLTTDPYEPGCQVLPNVNTLTRNAAK---------
Mb1653c|M.bovis_AF2122/97 GSVAGVPSVRAISTVTPKYPQHLPELPDIATDSTAAVPAPERVFKDQILD
Rv1627c|M.tuberculosis_H37Rv GSVAGVPSVRAISTVTPKYPQHLPELPDIATDSTAAVPAPERVFKDQILD
MAB_2619|M.abscessus_ATCC_1997 GSVDGVPSVRAVATITPKYPQHLPELPDIATDSTAVVPAPERVFKDQIVD
: . . ..
MAV_1842|M.avium_104 AAYEIAGIGPEDIDVAQLQDTDSGS-EVIHMAETMLCKDGEQEALLADGA
TH_3921|M.thermoresistible__bu AAYELAGIGPEDVDVAQLQDTDAGS-EIIHMAETGLCKDGEQEALLREGA
Mflv_2519|M.gilvum_PYR-GCK AAYEAAGIGPEDVDIAQLQDTDAGA-EVIHMAETGLCADGEQEKLLADGA
Mvan_4139|M.vanbaalenii_PYR-1 AAYEAAGIGPEDVDIAQLQDTDAGA-EVIHMAETGLCADGEQEKLLADGA
MSMEG_2236|M.smegmatis_MC2_155 AAFEKAGVAPEDVDVIQLQDTDAGA-EIIHMAECGFCAHGDQEKLLADGA
MLBr_02158|M.leprae_Br4923 AVYRGRQASDLRTSTSPSCRTSVPAPEVIQMDETVLCADGEQEKLASW--
MMAR_0142|M.marinum_M TAYEQAGVGPSDLDLVELHDCFATA-ELVHYDNLMLCEQGGAADFFESGA
MUL_4955|M.ulcerans_Agy99 TAYEQAGVGPSDLDLVELHDCFATA-ELVHYDNLMLCEQGGAADFFESGA
Mb1653c|M.bovis_AF2122/97 AAYAEAGIGPEDLSLAEVYDLSTAL-ELDWYEHLGLCPKGEAEALLRSGA
Rv1627c|M.tuberculosis_H37Rv AAYAEAGIGPEDLSLAEVYDLSTAL-ELDWYEHLGLCPKGEAEALLRSGA
MAB_2619|M.abscessus_ATCC_1997 AAYAEAGIGPEDISLAEVYDLSTAL-ELDWYEHLGLCAKGEGEQLLRSGA
:.: . . *: . :* .* :
MAV_1842|M.avium_104 TQIGGRLPINTDGGLLANGEPVGASGLRQVFELVHQLRGTAGDRQVPNEP
TH_3921|M.thermoresistible__bu TNIGGRLPINTDGGLLANGEPVGASGLRQVYELVHQLRGTAGDRQVPNDP
Mflv_2519|M.gilvum_PYR-GCK TEIHGSIPVNTDGGLIANGEPIGASGLRQVHELVRQLRGEAGDRQVPGAP
Mvan_4139|M.vanbaalenii_PYR-1 TEIHGSIPVNTDGGLIANGEPIGASGLRQVHELVRQLRGQAGDRQVPGQP
MSMEG_2236|M.smegmatis_MC2_155 TEIGGSLPVNTDGGLIANGEPIGASGLRQIHELVRQLRGEAGDRQVPGEP
MLBr_02158|M.leprae_Br4923 --------------------------------------------------
MMAR_0142|M.marinum_M PWRDGSTPVNVSGGLQSKGHPIAATGIANVWEICHHLRGEAGDRQIDN-A
MUL_4955|M.ulcerans_Agy99 PWRHGSTPVNVSGGLQSKGHPIAATGIANVWEICHQLRGEAGDRQIDN-A
Mb1653c|M.bovis_AF2122/97 TTLGGRVPVNPSGGLACFGEAIPAQAIAQVCELTWQLRGQATGRQVAD-A
Rv1627c|M.tuberculosis_H37Rv TTLGGRVPVNPSGGLACFGEAIPAQAIAQVCELTWQLRGQATGRQVAD-A
MAB_2619|M.abscessus_ATCC_1997 TTVGGRVPVNASGGLACFGEAIPAQAIAQVCELTWQLRGQAGDRQVEG-A
MAV_1842|M.avium_104 RVALAQLYGAPGTAAVAILSR---
TH_3921|M.thermoresistible__bu RVALAQLYGSPGTAAVAILSK---
Mflv_2519|M.gilvum_PYR-GCK RVGLAQVYGAPGTASATILSL---
Mvan_4139|M.vanbaalenii_PYR-1 RVGLAQVYGAPGTASATILSL---
MSMEG_2236|M.smegmatis_MC2_155 KVGFAQLYGAPGTAGATILTR---
MLBr_02158|M.leprae_Br4923 ------------------------
MMAR_0142|M.marinum_M KVGLAHVIGLGSACGVHILERSAA
MUL_4955|M.ulcerans_Agy99 KVGLAHVIGLGSACGVHILERSAA
Mb1653c|M.bovis_AF2122/97 KVGVTANQGLFGHGSSVIVAR---
Rv1627c|M.tuberculosis_H37Rv KVGVTANQGLFGHGSSVIVAR---
MAB_2619|M.abscessus_ATCC_1997 RVGITANQGLFGNGSSVIVAR---