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M. avium 104 MAV_2500 (-)

annotation: acyl-CoA dehydrogenase middle domain-containing protein
coordinates: 2531091 - 2532338
length: 415

VTSESVEEFRGRARAWLAANMPRLDPARAALLQRDELSSWHRARELQKLLYDGGFAGICFPREYGGLGLS
YEYKKAFDAESVGYETPLLLNVPSFAICCATILDMGSEQQKRTHIAAALRGEEVLVQLLSEPSGGSDLAG
VLTRAERRGDRWIINGAKTWSTWAFAADYGLCLARTDWQVPKHEGLTMFLVPLAHPGVTINRIRQVNGSV
EFCEEFFDDVDVGDDAVLGEPGKGWDVASRQLYHERRTMGDGSEYTSGPGIAEAQDVSVDLLSLIDAVGG
PGDPRLQEAVGRALVHRAVHGQLSEHVFHAVVDGTLPPAAGSIIRLSMAEVHNVETDTALAVAGPAAVVD
GAGGLLDIGTRYLGRQIASIGGGTTEMARNVIGERVLGFLRERADDRGVPFNQVRRGRNPGGQRN

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. avium 104 MAV_2500 - - 100% (415) acyl-CoA dehydrogenase middle domain-containing protein
M. avium 104 MAV_1620 - e-164 69.61% (408) acyl-CoA dehydrogenase middle domain-containing protein
M. avium 104 MAV_1878 - 4e-48 31.57% (396) acyl-CoA dehydrogenase family protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3590c fadE30 2e-46 33.76% (391) acyl-CoA dehydrogenase FADE30
M. gilvum PYR-GCK Mflv_3794 - 1e-151 61.93% (415) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3560c fadE30 2e-46 33.76% (391) acyl-CoA dehydrogenase FADE30
M. leprae Br4923 MLBr_00737 fadE25 3e-14 29.50% (200) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_3122 - 1e-42 31.82% (374) putative acyl-CoA dehydrogenase
M. marinum M MMAR_3992 - 1e-159 68.56% (404) acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_2992 - 1e-155 65.12% (410) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_4121 - 1e-161 68.72% (406) PUTATIVE acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_3854 - 1e-155 67.57% (404) acyl-CoA dehydrogenase
M. vanbaalenii PYR-1 Mvan_2600 - 1e-154 64.10% (415) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3590c|M.bovis_AF2122/97           ---------------MQDVEEFRAQVRGWLADNLAG----EFAALKGLGG
Rv3560c|M.tuberculosis_H37Rv        ---------------MQDVEEFRAQVRGWLADNLAG----EFAALKGLGG
MAB_3122|M.abscessus_ATCC_1997      ----------------MPVTSSEPSSAGSNALHTSGSSQRDRVAAAAHEV
Mflv_3794|M.gilvum_PYR-GCK          MTETMTST--ESTGTVETVEQFAARARTWLAENMPS-----IDPDNPPFS
Mvan_2600|M.vanbaalenii_PYR-1       MTDTMTST--ETT---ESVADFAARARTWLAENMPS-----IDPDDPPFS
MSMEG_2992|M.smegmatis_MC2_155      MTETAVST--GTQ---ESVEDFAARARAWLAGNMPR-----IDPDNPPFS
TH_4121|M.thermoresistible__bu      MTETTTTSQGRPAEITETVEEFAARARAWLAESMPR-----IDPDNPPNA
MMAR_3992|M.marinum_M               MTAV------------ESVAEFATRARKWLAANMSQ-----IDPLSPPEA
MUL_3854|M.ulcerans_Agy99           MTAV------------ESVAEFATRARKWLAANMSQ-----IDPLSPPEA
MAV_2500|M.avium_104                MTSE-------------SVEEFRGRARAWLAANMPR-----LDPARAALL
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAP-------------H
                                                        .             .               

Mb3590c|M.bovis_AF2122/97           PGREHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYA
Rv3560c|M.tuberculosis_H37Rv        PGREHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYA
MAB_3122|M.abscessus_ATCC_1997      LAKHPPATTPVTDLLGAVYDAGLAWVHFPVGLGGLDAPPALQAVSDTILR
Mflv_3794|M.gilvum_PYR-GCK          VRADQESWDRAKELQKRLYEGGFAGICFPREYGGLGLDYAYQRAFNAECR
Mvan_2600|M.vanbaalenii_PYR-1       VRAEQSSWDRAMELQKRLYEGGFAGICFPREYGGLGLDHAYQKAFNAECR
MSMEG_2992|M.smegmatis_MC2_155      VRADQESWDRAKELQKRLYQGGFAGICFPREYGGLGLDHAYQRAFNAEAR
TH_4121|M.thermoresistible__bu      DRGEEEPWLRARELQKRLYEGGFAGICFPREYGGLGLPYEYQKAFDAETA
MMAR_3992|M.marinum_M               PRDDEASWQRARQLQRRLHDGGFAGICFPREYGGQGLAYEYQRAFDEESL
MUL_3854|M.ulcerans_Agy99           PRDDEASWQRARQLQRRPNDGGFAGICFPREYGGQGLAYEYQRAFDEESL
MAV_2500|M.avium_104                QRDELSSWHRARELQKLLYDGGFAGICFPREYGGLGLSYEYKKAFDAESV
MLBr_00737|M.leprae_Br4923          AADVDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVA
                                                        .*:  :  *   ** .              

Mb3590c|M.bovis_AF2122/97           RADAPD--KVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYS
Rv3560c|M.tuberculosis_H37Rv        RADAPD--KVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYS
MAB_3122|M.abscessus_ATCC_1997      AAGVPDPLFVNVIGYGMAAPTVLAHGQPELIRRILRPLFTGEELWCQLFS
Mflv_3794|M.gilvum_PYR-GCK          SYEMPL--ILNVPTFTICAATILDMGTEDQKRDRISAAVRGDEILCQLLS
Mvan_2600|M.vanbaalenii_PYR-1       CYEMPL--ILNVPTFTICAATILDMGSEAQKRDRISAAIRGDEILCQLLS
MSMEG_2992|M.smegmatis_MC2_155      CYEMPL--ILNTPSFTICAATILDMGSEQQKRDRIGAAIRGEEILVQLLS
TH_4121|M.thermoresistible__bu      EYELPL--ILNTPTFTICCATILDTGSEQQKRKHISAAIRGDEVLVQLLS
MMAR_3992|M.marinum_M               HYEMPL--ILNVPTFTICCATLLDTGSESQKKRHIAAALRGEEVLVQLLS
MUL_3854|M.ulcerans_Agy99           HYEMPL--ILNVPTFTICCATLLDTGSENQKKRHIAAALRGEEVLVQLLS
MAV_2500|M.avium_104                GYETPL--LLNVPSFAICCATILDMGSEQQKRTHIAAALRGEEVLVQLLS
MLBr_00737|M.leprae_Br4923          RVDASAS--LIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALS
                                        .    :      :    ::  *     :  :        :     *

Mb3590c|M.bovis_AF2122/97           EPGAGSDLASVATTAELDGDQWVINGQKVWTSLAHLSQWCFVLARTEKGS
Rv3560c|M.tuberculosis_H37Rv        EPGAGSDLASVATTAELDGDQWVINGQKVWTSLAHLSQWCFVLARTEKGS
MAB_3122|M.abscessus_ATCC_1997      EPGAGSDLAGLATRAVRDGDEWVINGQKVWTSGAHQARWALLVARSNPDV
Mflv_3794|M.gilvum_PYR-GCK          EPSGGSDLAGVITRADKQGDTWIINGAKTWSTSAFAADYGLLLARTDWTV
Mvan_2600|M.vanbaalenii_PYR-1       EPSGGSDLAGVITRAERNGDKWIINGAKTWSTSAFAADYGLLLARTDWTV
MSMEG_2992|M.smegmatis_MC2_155      EPSGGSDLAGVITRADRVGDKWVINGAKTWSTSAFAGDYGLMLARTNWDV
TH_4121|M.thermoresistible__bu      EPSGGSDLAGVITRADRRGDKWVINGAKTWSTSAFAADYGLLLARTNWDV
MMAR_3992|M.marinum_M               EPSGGSDLAGVLTRAERQGDRWVINGAKTWSTSAFAADYGLCLARTNWDV
MUL_3854|M.ulcerans_Agy99           EHSGGSDLAGVLTRAERQGDRWVINGAKTWSTSAFAADYGLCLARTNWDV
MAV_2500|M.avium_104                EPSGGSDLAGVLTRAERRGDRWIINGAKTWSTWAFAADYGLCLARTDWQV
MLBr_00737|M.leprae_Br4923          EREAGSDAASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPD-
                                    *  .*** *.: * *   ** *::** * * : .  . :   :* ::   

Mb3590c|M.bovis_AF2122/97           QRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTDADLVV
Rv3560c|M.tuberculosis_H37Rv        QRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTDADLVV
MAB_3122|M.abscessus_ATCC_1997      AKHRGLTYFVVDMTDPGVEVRPLRQMTGD--AEFNEVYLTDVRIPDAHRL
Mflv_3794|M.gilvum_PYR-GCK          PKHEGLTMFLVPLDSPGITMRRIKEVNGN--EEFCEEFFDGLELGADAVV
Mvan_2600|M.vanbaalenii_PYR-1       PKHEGLTMFLVPLNAPGITMRRIKEVNGN--EEFCEEFFDGLELGDDAVV
MSMEG_2992|M.smegmatis_MC2_155      PKHEGLTMFLVPLKAPGITMRRIKEVNGN--EEFCEEFFDNLELGDDAVV
TH_4121|M.thermoresistible__bu      PKHEGLTMFLVPLDAPGITMRRIKQVDGG--NEFCEEFFDNVEVGDDAVV
MMAR_3992|M.marinum_M               PKHDGLTMFLVPINHPGITLRRITQVNGS--TEFCEEFLDGVDVGDDAVV
MUL_3854|M.ulcerans_Agy99           PKHDGLTMFLVPINHPGITLRRITQVNGS--TEFCEEFLDSVDVGDDAVV
MAV_2500|M.avium_104                PKHEGLTMFLVPLAHPGVTINRIRQVNGS--VEFCEEFFDDVDVGDDAVL
MLBr_00737|M.leprae_Br4923          KGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRII
                                        *:: ::*     *. :    :  *       * ::          :

Mb3590c|M.bovis_AF2122/97           GAPGDGWRVAMATLTFERGVSTLGQQIVYAR-------ELSNLVELARRT
Rv3560c|M.tuberculosis_H37Rv        GAPGDGWRVAMATLTFERGVSTLGQQIVYAR-------ELSNLVELARRT
MAB_3122|M.abscessus_ATCC_1997      GNEGDGWRVSMTTLMNER--SALGGAFDHGRGG----GSIGNALNLWKQR
Mflv_3794|M.gilvum_PYR-GCK          GEVNKGWEVATRQLHHERRAVGGGSEFASGTAAENASEMPPDHVGLAEAT
Mvan_2600|M.vanbaalenii_PYR-1       GEVNKGWEVATRQLHHERRAVGGGSEFASGTAAENASEMPPDHVGLARAT
MSMEG_2992|M.smegmatis_MC2_155      GKVDDGWTVASRQLFHERRAVGGGSEFASGTGAENANEMPPDHVGLAEAL
TH_4121|M.thermoresistible__bu      GEVDKGWEVASRQLYHERRAVGGGSEFASGIGAEGSTDQPVDYVALLAAT
MMAR_3992|M.marinum_M               GEVNNGWTVASRQLYHERRAVGMGSEFASGAGSEGGHATPVDYVALAETT
MUL_3854|M.ulcerans_Agy99           GEVNNGWTVASRQLYHERRAVGIGSEFASGAGSEGGHATPVDYVALAETT
MAV_2500|M.avium_104                GEPGKGWDVASRQLYHERRTMGDGSEYTSGPGIAEAQDVSVDLLSLIDAV
MLBr_00737|M.leprae_Br4923          GEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESI
                                    *  . *: .:   *   *                       :   :    

Mb3590c|M.bovis_AF2122/97           AAADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQD--NVSKLLW
Rv3560c|M.tuberculosis_H37Rv        AAADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQD--NVSKLLW
MAB_3122|M.abscessus_ATCC_1997      PDLHTPELRAKLTNLFVRSEGNRYGTQMRIAAQGDAPMGPEG-SIGKLMG
Mflv_3794|M.gilvum_PYR-GCK          GQSDNPLVQDLAGRALVRRIVKEQLIDHVFRSITDGSLPPNAGTLIRLFH
Mvan_2600|M.vanbaalenii_PYR-1       GQDGDPRVQDLAGRALVRRIVKEQLIDHVFRSIGNGSLPPNAGTLIRLFH
MSMEG_2992|M.smegmatis_MC2_155      GRADDPFVQDLAGRALVRRAVKTQLIDHVTQAIAAGALPPTAGTLIRLFH
TH_4121|M.thermoresistible__bu      GQSDSLRAQELAGRALVHRAVQDQLVEHVYHAVNDGTLPPAGGSIIRVTH
MMAR_3992|M.marinum_M               GQAHSDRVREMAGRALVHRAVCEQLIDHVYRSVRDGTLPPAAGTLIRLFH
MUL_3854|M.ulcerans_Agy99           GQAHSDRVREMAGRALVHRAVCEQLIDHVYRSVRDGTLPPAAGTLIRLFH
MAV_2500|M.avium_104                GGPGDPRLQEAVGRALVHRAVHGQLSEHVFHAVVDGTLPPAAGSIIRLSM
MLBr_00737|M.leprae_Br4923          STFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFIS-AASKCFA
                                                    .                             :   

Mb3590c|M.bovis_AF2122/97           ANWHRNLGELAMDVIGKPGMTMP---------DGEFDEWQRLYLFTRADT
Rv3560c|M.tuberculosis_H37Rv        ANWHRNLGELAMDVIGKPGMTMP---------DGEFDEWQRLYLFTRADT
MAB_3122|M.abscessus_ATCC_1997      AELNQQIYDFCVELLGIEATLYASYDMRRVVEDDRRADTMWAFLRSKANT
Mflv_3794|M.gilvum_PYR-GCK          AETTELEVDTALAIAGTAGVIDEGSDD--APELSGLLEIGVRYLSRQTGS
Mvan_2600|M.vanbaalenii_PYR-1       AETTELEVDTALAIAGTAGVVDEGSDD--APGLTGLMDVGVRYLSRQTGS
MSMEG_2992|M.smegmatis_MC2_155      AETTELEVDTALAIAGTAGVVDEGGD------FDGMLDIGVRYLSRQTGS
TH_4121|M.thermoresistible__bu      AEHIQVEVDTALALAGSGGVVDDSRD---------LFRFGERYLSRQAAA
MMAR_3992|M.marinum_M               AETVMCEMDTSLAIAGSGGVVGQPGE---------GLQTGLRYLARQSVA
MUL_3854|M.ulcerans_Agy99           AETVMCEMDTSLAIAGSGGVVGQPGE---------GLQTGLRYLARQSVA
MAV_2500|M.avium_104                AEVHNVETDTALAVAGPAAVVDGAGG---------LLDIGTRYLGRQIAS
MLBr_00737|M.leprae_Br4923          SDIAMEVTTDAVQLFGGAGYTSD-------------FPVERFMRDAKITQ
                                    ::        .: : *  .                           :   

Mb3590c|M.bovis_AF2122/97           IYGGSNEIQRNIIAERVLGLPREAKG--------------------
Rv3560c|M.tuberculosis_H37Rv        IYGGSNEIQRNIIAERVLGLPREAKG--------------------
MAB_3122|M.abscessus_ATCC_1997      IEGGTSDVMRNIIGERVLGLPGDIRVDTDKAWKDVPRG--------
Mflv_3794|M.gilvum_PYR-GCK          LGGGSSEMARNVIGERILGFPRELAADKGIPFNEVKRNKS------
Mvan_2600|M.vanbaalenii_PYR-1       LGGGSSEMARNVISERILGFPRELAADKGIPFNQVKRNKS------
MSMEG_2992|M.smegmatis_MC2_155      LGGGSSEMARNVIGERVLGFPREHAADRGVPFREVKRNKG------
TH_4121|M.thermoresistible__bu      LGGGTTEIARNIIAERILGFPREPAADRGMPFKDVKRNRG------
MMAR_3992|M.marinum_M               IGGGTTEMARNVIGERMLNFPREFAADRGVPFNQVRRGPPR-----
MUL_3854|M.ulcerans_Agy99           IGGGPTEMARNVIGERMLNFPREFAADRGVSFNQVRRGSPR-----
MAV_2500|M.avium_104                IGGGTTEMARNVIGERVLGFLRERADDRGVPFNQVRRGRNPGGQRN
MLBr_00737|M.leprae_Br4923          IYEGTNQIQRVVMSRALLR---------------------------
                                    :  *..:: * ::.. :*

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_2500	-	-	100% (415)	acyl-CoA dehydrogenase middle domain-containing protein
M. avium 104	MAV_1620	-	e-164	69.61% (408)	acyl-CoA dehydrogenase middle domain-containing protein
M. avium 104	MAV_1878	-	4e-48	31.57% (396)	acyl-CoA dehydrogenase family protein