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M. vanbaalenii PYR-1 Mvan_2600 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 2747884 - 2749158
length: 424

TDTMTSTETTESVADFAARARTWLAENMPSIDPDDPPFSVRAEQSSWDRAMELQKRLYEGGFAGICFPRE
YGGLGLDHAYQKAFNAECRCYEMPLILNVPTFTICAATILDMGSEAQKRDRISAAIRGDEILCQLLSEPS
GGSDLAGVITRAERNGDKWIINGAKTWSTSAFAADYGLLLARTDWTVPKHEGLTMFLVPLNAPGITMRRI
KEVNGNEEFCEEFFDGLELGDDAVVGEVNKGWEVATRQLHHERRAVGGGSEFASGTAAENASEMPPDHVG
LARATGQDGDPRVQDLAGRALVRRIVKEQLIDHVFRSIGNGSLPPNAGTLIRLFHAETTELEVDTALAIA
GTAGVVDEGSDDAPGLTGLMDVGVRYLSRQTGSLGGGSSEMARNVISERILGFPRELAADKGIPFNQVKR
NKS*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. vanbaalenii PYR-1 Mvan_2600 - - 100% (424) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_4313 - 2e-48 30.24% (420) acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1 Mvan_0394 - 2e-48 32.45% (376) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3590c fadE30 2e-42 30.88% (408) acyl-CoA dehydrogenase FADE30
M. gilvum PYR-GCK Mflv_3794 - 0.0 90.63% (427) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3560c fadE30 2e-42 30.88% (408) acyl-CoA dehydrogenase FADE30
M. leprae Br4923 MLBr_00737 fadE25 3e-15 27.59% (203) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_3122 - 4e-42 30.69% (378) putative acyl-CoA dehydrogenase
M. marinum M MMAR_3992 - 1e-163 67.32% (410) acyl-CoA dehydrogenase
M. avium 104 MAV_1620 - 1e-170 70.53% (414) acyl-CoA dehydrogenase middle domain-containing protein
M. smegmatis MC2 155 MSMEG_2992 - 0.0 83.22% (423) putative acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_4121 - 1e-174 69.63% (428) PUTATIVE acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_3854 - 1e-158 66.34% (410) acyl-CoA dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb3590c|M.bovis_AF2122/97           ---------------MQDVEEFRAQVRGWLADNLAG----EFAALKGLGG
Rv3560c|M.tuberculosis_H37Rv        ---------------MQDVEEFRAQVRGWLADNLAG----EFAALKGLGG
MAB_3122|M.abscessus_ATCC_1997      ----------------MPVTSSEPSSAGSNALHTSGSSQRDRVAAAAHEV
Mvan_2600|M.vanbaalenii_PYR-1       --MTDTMTSTETT---ESVADFAARARTWLAENMPSID-----PDDPPFS
Mflv_3794|M.gilvum_PYR-GCK          --MTETMTSTESTGTVETVEQFAARARTWLAENMPSID-----PDNPPFS
MSMEG_2992|M.smegmatis_MC2_155      --MTETAVSTGTQ---ESVEDFAARARAWLAGNMPRID-----PDNPPFS
MMAR_3992|M.marinum_M               ------------MTAVESVAEFATRARKWLAANMSQID-----PLSPPEA
MUL_3854|M.ulcerans_Agy99           ------------MTAVESVAEFATRARKWLAANMSQID-----PLSPPEA
MAV_1620|M.avium_104                -------------MTTESVAQFAARARAWLADNMPAID-----RESPPPA
TH_4121|M.thermoresistible__bu      MTETTTTSQGRPAEITETVEEFAARARAWLAESMPRID-----PDNPPNA
MLBr_00737|M.leprae_Br4923          -------MVGWSGNPLFDLFKLPEEHNELRATIRALAE-----KEIAPHA
                                                      : .         *   .               

Mb3590c|M.bovis_AF2122/97           PGREHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYA
Rv3560c|M.tuberculosis_H37Rv        PGREHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYA
MAB_3122|M.abscessus_ATCC_1997      LAKHPPATTPVTDLLGAVYDAGLAWVHFPVGLGGLDAPPALQAVSDTILR
Mvan_2600|M.vanbaalenii_PYR-1       VRAEQSSWDRAMELQKRLYEGGFAGICFPREYGGLGLDHAYQKAFNAECR
Mflv_3794|M.gilvum_PYR-GCK          VRADQESWDRAKELQKRLYEGGFAGICFPREYGGLGLDYAYQRAFNAECR
MSMEG_2992|M.smegmatis_MC2_155      VRADQESWDRAKELQKRLYQGGFAGICFPREYGGLGLDHAYQRAFNAEAR
MMAR_3992|M.marinum_M               PRDDEASWQRARQLQRRLHDGGFAGICFPREYGGQGLAYEYQRAFDEESL
MUL_3854|M.ulcerans_Agy99           PRDDEASWQRARQLQRRPNDGGFAGICFPREYGGQGLAYEYQRAFDEESL
MAV_1620|M.avium_104                PRDDERAWRRARELQKRLYDGGFAGICFPREYGGLGLDYEYQKAFDAESL
TH_4121|M.thermoresistible__bu      DRGEEEPWLRARELQKRLYEGGFAGICFPREYGGLGLPYEYQKAFDAETA
MLBr_00737|M.leprae_Br4923          ADVDQRARFP-EEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVA
                                       .  .             .*:  :  *   ** .              

Mb3590c|M.bovis_AF2122/97           RADAPD--KVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYS
Rv3560c|M.tuberculosis_H37Rv        RADAPD--KVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYS
MAB_3122|M.abscessus_ATCC_1997      AAGVPDPLFVNVIGYGMAAPTVLAHGQPELIRRILRPLFTGEELWCQLFS
Mvan_2600|M.vanbaalenii_PYR-1       CYEMPL--ILNVPTFTICAATILDMGSEAQKRDRISAAIRGDEILCQLLS
Mflv_3794|M.gilvum_PYR-GCK          SYEMPL--ILNVPTFTICAATILDMGTEDQKRDRISAAVRGDEILCQLLS
MSMEG_2992|M.smegmatis_MC2_155      CYEMPL--ILNTPSFTICAATILDMGSEQQKRDRIGAAIRGEEILVQLLS
MMAR_3992|M.marinum_M               HYEMPL--ILNVPTFTICCATLLDTGSESQKKRHIAAALRGEEVLVQLLS
MUL_3854|M.ulcerans_Agy99           HYEMPL--ILNVPTFTICCATLLDTGSENQKKRHIAAALRGEEVLVQLLS
MAV_1620|M.avium_104                DYEMPL--ILNTPTFTICCATLLDTGSEQQKKQHIAAALRGEEILVQLLS
TH_4121|M.thermoresistible__bu      EYELPL--ILNTPTFTICCATILDTGSEQQKRKHISAAIRGDEVLVQLLS
MLBr_00737|M.leprae_Br4923          RVDASAS--LIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALS
                                        .    :      :    ::  *     :  :        :     *

Mb3590c|M.bovis_AF2122/97           EPGAGSDLASVATTAELDGDQWVINGQKVWTSLAHLSQWCFVLARTEKGS
Rv3560c|M.tuberculosis_H37Rv        EPGAGSDLASVATTAELDGDQWVINGQKVWTSLAHLSQWCFVLARTEKGS
MAB_3122|M.abscessus_ATCC_1997      EPGAGSDLAGLATRAVRDGDEWVINGQKVWTSGAHQARWALLVARSNPDV
Mvan_2600|M.vanbaalenii_PYR-1       EPSGGSDLAGVITRAERNGDKWIINGAKTWSTSAFAADYGLLLARTDWTV
Mflv_3794|M.gilvum_PYR-GCK          EPSGGSDLAGVITRADKQGDTWIINGAKTWSTSAFAADYGLLLARTDWTV
MSMEG_2992|M.smegmatis_MC2_155      EPSGGSDLAGVITRADRVGDKWVINGAKTWSTSAFAGDYGLMLARTNWDV
MMAR_3992|M.marinum_M               EPSGGSDLAGVLTRAERQGDRWVINGAKTWSTSAFAADYGLCLARTNWDV
MUL_3854|M.ulcerans_Agy99           EHSGGSDLAGVLTRAERQGDRWVINGAKTWSTSAFAADYGLCLARTNWDV
MAV_1620|M.avium_104                EPSGGSDLAGVLTRAERRGDRWIINGAKTWSTSAFAADYGLCLARTNWDV
TH_4121|M.thermoresistible__bu      EPSGGSDLAGVITRADRRGDKWVINGAKTWSTSAFAADYGLLLARTNWDV
MLBr_00737|M.leprae_Br4923          EREAGSDAASMRTRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPD-
                                    *  .*** *.: * *   ** *::** * * : .  . :   :* ::   

Mb3590c|M.bovis_AF2122/97           QRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTDADLVV
Rv3560c|M.tuberculosis_H37Rv        QRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTDADLVV
MAB_3122|M.abscessus_ATCC_1997      AKHRGLTYFVVDMTDPGVEVRPLRQMTGD--AEFNEVYLTDVRIPDAHRL
Mvan_2600|M.vanbaalenii_PYR-1       PKHEGLTMFLVPLNAPGITMRRIKEVNGN--EEFCEEFFDGLELGDDAVV
Mflv_3794|M.gilvum_PYR-GCK          PKHEGLTMFLVPLDSPGITMRRIKEVNGN--EEFCEEFFDGLELGADAVV
MSMEG_2992|M.smegmatis_MC2_155      PKHEGLTMFLVPLKAPGITMRRIKEVNGN--EEFCEEFFDNLELGDDAVV
MMAR_3992|M.marinum_M               PKHDGLTMFLVPINHPGITLRRITQVNGS--TEFCEEFLDGVDVGDDAVV
MUL_3854|M.ulcerans_Agy99           PKHDGLTMFLVPINHPGITLRRITQVNGS--TEFCEEFLDSVDVGDDAVV
MAV_1620|M.avium_104                PKHEGLTMFLVPINHPGITLRRITMLSGS--TEFCEEFLDGVDVGDDAVV
TH_4121|M.thermoresistible__bu      PKHEGLTMFLVPLDAPGITMRRIKQVDGG--NEFCEEFFDNVEVGDDAVV
MLBr_00737|M.leprae_Br4923          KGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRII
                                        *:: ::*     *. :       *       * ::          :

Mb3590c|M.bovis_AF2122/97           GAPGDGWRVAMATLTFERGVSTLGQQIVYAR-------ELSNLVELARRT
Rv3560c|M.tuberculosis_H37Rv        GAPGDGWRVAMATLTFERGVSTLGQQIVYAR-------ELSNLVELARRT
MAB_3122|M.abscessus_ATCC_1997      GNEGDGWRVSMTTLMNER--SALGGAFDHGRGG----GSIGNALNLWKQR
Mvan_2600|M.vanbaalenii_PYR-1       GEVNKGWEVATRQLHHERRAVGGGSEFASGTAAENASEMPPDHVGLARAT
Mflv_3794|M.gilvum_PYR-GCK          GEVNKGWEVATRQLHHERRAVGGGSEFASGTAAENASEMPPDHVGLAEAT
MSMEG_2992|M.smegmatis_MC2_155      GKVDDGWTVASRQLFHERRAVGGGSEFASGTGAENANEMPPDHVGLAEAL
MMAR_3992|M.marinum_M               GEVNNGWTVASRQLYHERRAVGMGSEFASGAGSEGGHATPVDYVALAETT
MUL_3854|M.ulcerans_Agy99           GEVNNGWTVASRQLYHERRAVGIGSEFASGAGSEGGHATPVDYVALAETT
MAV_1620|M.avium_104                GEVNGGWAVASRQLYHERRAVGQGSEFASGGGSEGGHTIPVDYVSLAEKT
TH_4121|M.thermoresistible__bu      GEVDKGWEVASRQLYHERRAVGGGSEFASGIGAEGSTDQPVDYVALLAAT
MLBr_00737|M.leprae_Br4923          GEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESI
                                    *  . *: .:   *   *                       :   :    

Mb3590c|M.bovis_AF2122/97           AAADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQD--NVSKLLW
Rv3560c|M.tuberculosis_H37Rv        AAADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQD--NVSKLLW
MAB_3122|M.abscessus_ATCC_1997      PDLHTPELRAKLTNLFVRSEGNRYGTQMRIAAQGDAPMGPEG-SIGKLMG
Mvan_2600|M.vanbaalenii_PYR-1       GQDGDPRVQDLAGRALVRRIVKEQLIDHVFRSIGNGSLPPNAGTLIRLFH
Mflv_3794|M.gilvum_PYR-GCK          GQSDNPLVQDLAGRALVRRIVKEQLIDHVFRSITDGSLPPNAGTLIRLFH
MSMEG_2992|M.smegmatis_MC2_155      GRADDPFVQDLAGRALVRRAVKTQLIDHVTQAIAAGALPPTAGTLIRLFH
MMAR_3992|M.marinum_M               GQAHSDRVREMAGRALVHRAVCEQLIDHVYRSVRDGTLPPAAGTLIRLFH
MUL_3854|M.ulcerans_Agy99           GQAHSDRVREMAGRALVHRAVCEQLIDHVYRSVRDGTLPPAAGTLIRLFH
MAV_1620|M.avium_104                GQADDPRVQEMAGRVLVHRAVAEQLIGHVYRSVRDGALPPAAGTLIRLFH
TH_4121|M.thermoresistible__bu      GQSDSLRAQELAGRALVHRAVQDQLVEHVYHAVNDGTLPPAGGSIIRVTH
MLBr_00737|M.leprae_Br4923          STFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFIS-AASKCFA
                                                    .                             :   

Mb3590c|M.bovis_AF2122/97           ANWHRNLGELAMDVIGKPGMTMP---------DGEFDEWQRLYLFTRADT
Rv3560c|M.tuberculosis_H37Rv        ANWHRNLGELAMDVIGKPGMTMP---------DGEFDEWQRLYLFTRADT
MAB_3122|M.abscessus_ATCC_1997      AELNQQIYDFCVELLGIEATLYASYDMRRVVEDDRRADTMWAFLRSKANT
Mvan_2600|M.vanbaalenii_PYR-1       AETTELEVDTALAIAGTAGVVDEGSDD--APGLTGLMDVGVRYLSRQTGS
Mflv_3794|M.gilvum_PYR-GCK          AETTELEVDTALAIAGTAGVIDEGSDD--APELSGLLEIGVRYLSRQTGS
MSMEG_2992|M.smegmatis_MC2_155      AETTELEVDTALAIAGTAGVVDEGGD------FDGMLDIGVRYLSRQTGS
MMAR_3992|M.marinum_M               AETVMCEMDTSLAIAGSGGVVGQPGE---------GLQTGLRYLARQSVA
MUL_3854|M.ulcerans_Agy99           AETVMCEMDTSLAIAGSGGVVGQPGE---------GLQTGLRYLARQSVA
MAV_1620|M.avium_104                SETVTTDVDTALAIAGSAGVVGEPGA---------GLETGLRYLSRQTVA
TH_4121|M.thermoresistible__bu      AEHIQVEVDTALALAGSGGVVDDSRD---------LFRFGERYLSRQAAA
MLBr_00737|M.leprae_Br4923          SDIAMEVTTDAVQLFGGAGYTSD-------------FPVERFMRDAKITQ
                                    ::        .: : *  .                           :   

Mb3590c|M.bovis_AF2122/97           IYGGSNEIQRNIIAERVLGLPREAKG------------------
Rv3560c|M.tuberculosis_H37Rv        IYGGSNEIQRNIIAERVLGLPREAKG------------------
MAB_3122|M.abscessus_ATCC_1997      IEGGTSDVMRNIIGERVLGLPGDIRVDTDKAWKDVPRG------
Mvan_2600|M.vanbaalenii_PYR-1       LGGGSSEMARNVISERILGFPRELAADKGIPFNQVKRN----KS
Mflv_3794|M.gilvum_PYR-GCK          LGGGSSEMARNVIGERILGFPRELAADKGIPFNEVKRN----KS
MSMEG_2992|M.smegmatis_MC2_155      LGGGSSEMARNVIGERVLGFPREHAADRGVPFREVKRN----KG
MMAR_3992|M.marinum_M               IGGGTTEMARNVIGERMLNFPREFAADRGVPFNQVRRG--PPR-
MUL_3854|M.ulcerans_Agy99           IGGGPTEMARNVIGERMLNFPREFAADRGVSFNQVRRG--SPR-
MAV_1620|M.avium_104                IGGGTTEMARNVIGERVLGFPREYAADRGVPFNQVRHGQRSDRS
TH_4121|M.thermoresistible__bu      LGGGTTEIARNIIAERILGFPREPAADRGMPFKDVKRN----RG
MLBr_00737|M.leprae_Br4923          IYEGTNQIQRVVMSRALLR-------------------------
                                    :  *..:: * ::.. :*

species	id	gene	e-value	identity (len)	annotation
M. vanbaalenii PYR-1	Mvan_2600	-	-	100% (424)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_4313	-	2e-48	30.24% (420)	acyl-CoA dehydrogenase domain-containing protein
M. vanbaalenii PYR-1	Mvan_0394	-	2e-48	32.45% (376)	acyl-CoA dehydrogenase domain-containing protein