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AFIGQGVNSLLNPKSAAEAAAPAVDGLQALPDPVSGNIPSDPETVAQITAAVQIGGGLLLATGKLPRVAS AALALTVLPANLGAHSFWNESDPVAKAQKRQQFLTDLSLLGGLLIASADTAGKPSLGWRGRRAAERLSER VSSAWPGSDDSGFEADLSELGERIAHGLQIGAERGRELASTAAERGAPYAEAALERGRELASTAAERGAP YAEAALERGRELASTAAERGRPLAKKARKRGEELADEAAERAAYLAQKARKRSEELAEEAAERGKPLAKK ARKRSEKLAKKARKRSEKLAGTARVRGEELAETARQRGSLLADTARERVGGQVGTGRRKLSW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2471 | - | - | 100% (343) | DoxX subfamily protein, putative |
| M. avium 104 | MAV_2345 | - | 5e-06 | 22.15% (158) | Wag31 protein |
| M. avium 104 | MAV_3650 | - | 1e-05 | 27.33% (161) | hypothetical protein MAV_3650 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3130 | - | 2e-81 | 53.85% (299) | DoxX family protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4785 | - | 2e-42 | 42.49% (233) | hypothetical protein MAB_4785 |
| M. marinum M | MMAR_3017 | - | 1e-98 | 74.10% (251) | hypothetical protein MMAR_3017 |
| M. smegmatis MC2 155 | MSMEG_3255 | - | 6e-78 | 53.40% (294) | DoxX subfamily protein, putative |
| M. thermoresistible (build 8) | TH_4441 | - | 2e-29 | 61.46% (96) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2258 | - | 3e-99 | 74.10% (251) | hypothetical protein MUL_2258 |
| M. vanbaalenii PYR-1 | Mvan_3403 | - | 4e-74 | 54.09% (281) | DoxX family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3017|M.marinum_M MLIRRIARPMLSAAFIGQGVESLLNPKPAAQAAAPAVAGLRTLPEPMGSR
MUL_2258|M.ulcerans_Agy99 MLIRRIARPMLSAAFIGQGVESLLNPKPAAQAAAPAVAGLRTLPEPMGSR
MAV_2471|M.avium_104 ------------MAFIGQGVNSLLNPKSAAEAAAPAVDGLQALPDPVSGN
Mflv_3130|M.gilvum_PYR-GCK MLIRRVARPMLSAVFISRGVDALRSPKPATDATRQTLEELSKLPDPVGTK
Mvan_3403|M.vanbaalenii_PYR-1 MLIRRVARPMLSAVFISRGVEALRSPKPAADATRHTLEGLSKLPDPVGTN
MSMEG_3255|M.smegmatis_MC2_155 ---------MLSATFIARGVDALRNPKPAADAARPTLGMMSSLPDPVGSK
MAB_4785|M.abscessus_ATCC_1997 ---------MLGSIFIVAGADGLTRPSASVAATEPLVSSLLEHTPESARR
TH_4441|M.thermoresistible__bu ---------MLSAVFIGRGVDAVRSPKPAADAARPTIEGLTKLPEPVGPR
** *.:.: *..:. *: : : . . .
MMAR_3017|M.marinum_M --VPADPETVAQINAAVQIGGGLLLATGRLPRLASAALALTVVPGNLGAH
MUL_2258|M.ulcerans_Agy99 --VPADPETVAQINAAVQIGGGLLLATGRLPRLASAALALTVVPGNLGAH
MAV_2471|M.avium_104 --IPSDPETVAQITAAVQIGGGLLLATGKLPRVASAALALTVLPANLGAH
Mflv_3130|M.gilvum_PYR-GCK VPVPSNAETVAKVTAAVQIGGGLLLATGKLPRFASAALALSVVPGSLGGH
Mvan_3403|M.vanbaalenii_PYR-1 --VPSNAETVAKVAAAVQIGGGLLLATGRLPRVASAALALSVVPSSLGGH
MSMEG_3255|M.smegmatis_MC2_155 --VPSDAETVAKINGAVQVVGGLLLASGKMPRLTAAALALSVVPGSLGSH
MAB_4785|M.abscessus_ATCC_1997 -YLPSDPQTYVRIHGATQLAAGLALASGKLPRISAWVLAGTLVPATLTDQ
TH_4441|M.thermoresistible__bu --VPTDAETVARINGMVQIAGGALLATGKLPRVASAVLALSVVPGSLGGH
:*::.:* .:: . .*: .* **:*::**.:: .** :::*..* :
MMAR_3017|M.marinum_M MFWNEPDPDRKAQKRREFLTDVSLLGGLIIASADTAGKPSLAWRGRRAAE
MUL_2258|M.ulcerans_Agy99 MFWNEPDPDRKAQKRREFLTDVSLLGGLIIASADTAGKPSLAWRGRRAAE
MAV_2471|M.avium_104 SFWNESDPVAKAQKRQQFLTDLSLLGGLLIASADTAGKPSLGWRGRRAAE
Mflv_3130|M.gilvum_PYR-GCK SFWNEVDPQRKAEERRAFITDVSLIGGLIIAAVDTEGKPSLGWRGRRAAR
Mvan_3403|M.vanbaalenii_PYR-1 AFWNEADPQRKADERRAFVTDISLIGGLIIAAVDTEGKPSLGWRGRRAAH
MSMEG_3255|M.smegmatis_MC2_155 SFWKESDPQRSAQERREFLTDLSLIGGLIIAAADTEGKPSLAWRGRRAAH
MAB_4785|M.abscessus_ATCC_1997 AYWRQTDPALKLQQKTHFWKNISILGGLIIAGIDTEGRPGLSWRARRAAR
TH_4441|M.thermoresistible__bu MFWTESDPQRKAXXXTGGYPPAGFPPPGGFGASYRFG-DAFNWAWSAFTR
:* : ** . .: :.. * .: * :.
MMAR_3017|M.marinum_M QLSGAVSSALP------------------GSDDVRLES---ELGDKIVHG
MUL_2258|M.ulcerans_Agy99 KLSGAVSSALP------------------GSDDMRLES---ELGDKIVHG
MAV_2471|M.avium_104 RLSERVSSAWP------------------GSDDSGFEADLSELGERIAHG
Mflv_3130|M.gilvum_PYR-GCK KVSETVAAALP------------------AGAAAGSSLTDSAFAEKVGHG
Mvan_3403|M.vanbaalenii_PYR-1 KVSEAVAAALP------------------AGAAAGGSLADSEFVEKVEHG
MSMEG_3255|M.smegmatis_MC2_155 KVTASVAAALP------------------AGAAASESIADSAVAEKLGHG
MAB_4785|M.abscessus_ATCC_1997 DAVAAVTSALP------------------GVEQTSQSLG----AKTLELG
TH_4441|M.thermoresistible__bu HAAPLMLAALAYVAIIFALSFLFSLVLTAFTPGGATTVDPDSFFDMFGVG
: :* . . . *
MMAR_3017|M.marinum_M IQAGAER----------------GRELASTAAEKSAPYAEAALER-----
MUL_2258|M.ulcerans_Agy99 IQAGAER----------------GRELASTAAEKSAPYAEAALER-----
MAV_2471|M.avium_104 LQIGAER----------------GRELASTAAERGAPYAEAALER-----
Mflv_3130|M.gilvum_PYR-GCK LHVGAER----------------GRELAHVAGERGSELAEVARERGGKWA
Mvan_3403|M.vanbaalenii_PYR-1 LQVGAER----------------GRELAHVARERGGELAHVARER-----
MSMEG_3255|M.smegmatis_MC2_155 LSVGAER----------------GRELAEIARERAAELAHAAREH-----
MAB_4785|M.abscessus_ATCC_1997 -EATRER----------------IPDLVEHARERGAEIAETAQRR-----
TH_4441|M.thermoresistible__bu GTLTMVVGVILLLFVSGVITSAFLNGLLAIADGQQIELASFFRPRNVGSV
* * : * :
MMAR_3017|M.marinum_M ------GRELASTAAEK-----------GAPLAEAARRRG----------
MUL_2258|M.ulcerans_Agy99 ------GRELASTAAEK-----------GAPLAEAARRRG----------
MAV_2471|M.avium_104 ------GRELASTAAER-----------GAPYAEAALERGRELASTAAER
Mflv_3130|M.gilvum_PYR-GCK EVAREHGGELAEIARERGAELAEVARDRSAVLAERARDRA----------
Mvan_3403|M.vanbaalenii_PYR-1 ------APVLAEAARER----AETARERAAVLAELARERG----------
MSMEG_3255|M.smegmatis_MC2_155 ------APELAEAARER----SAHLAERGAVLADVARERG----------
MAB_4785|M.abscessus_ATCC_1997 ------GSQFAETASRR-----------GSELAERLSERG----------
TH_4441|M.thermoresistible__bu VIATVIVGVLSYIGTALCVVPGLIVSLFAMFTTVAVVDRNLSPIDG----
:: . . : *
MMAR_3017|M.marinum_M --------------------------------------------------
MUL_2258|M.ulcerans_Agy99 --------------------------------------------------
MAV_2471|M.avium_104 GRPLAKKARKRGEELADEAAERAAYLAQKARKRSEELAEEAAERGKPLAK
Mflv_3130|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3403|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_3255|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4785|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4441|M.thermoresistible__bu --------------------------------------------------
MMAR_3017|M.marinum_M -----------------ERLAHSARVRGA-----------ELAETARHQG
MUL_2258|M.ulcerans_Agy99 -----------------ERLAHSARVRGA-----------ELAETARHQG
MAV_2471|M.avium_104 KARKRSEKLAKKARKRSEKLAGTARVRGE-----------ELAETARQRG
Mflv_3130|M.gilvum_PYR-GCK -----------------PELADVARDRGTEWAELAR----DRAELARERA
Mvan_3403|M.vanbaalenii_PYR-1 -----------------PELAEAAR---------------ERAEAARERA
MSMEG_3255|M.smegmatis_MC2_155 -----------------LEFADVAQKRGLEFADVARGRGAELAETAREAA
MAB_4785|M.abscessus_ATCC_1997 -----------------SELASAAE-------------------KGRHQV
TH_4441|M.thermoresistible__bu ---------------ILASVDVVKKNFGPAILVWLASGVLIFLGSLLCGV
. .
MMAR_3017|M.marinum_M THLADTARARVEA-------PVR-GRRH---
MUL_2258|M.ulcerans_Agy99 TQLADTARARVEA-------PVR-GRRH---
MAV_2471|M.avium_104 SLLADTARERVGG-------QVGTGRRKLSW
Mflv_3130|M.gilvum_PYR-GCK AVLADTAGKEAKKVSKEAKKQAKKQQRRVR-
Mvan_3403|M.vanbaalenii_PYR-1 AMLADTAGTEVK-----------KQKRRLR-
MSMEG_3255|M.smegmatis_MC2_155 PELAETARAHGNVLANRTRKQLKQARRR---
MAB_4785|M.abscessus_ATCC_1997 EALAADPPPRVRR-------FVHAFIRR---
TH_4441|M.thermoresistible__bu GLLITGPLAGLLVVCTFRRLTGAPVAPQAV-
* . :