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ITEPVKTFSRKFMGYDTTAVDAHIEMLTAKQQLLIDDVESLRARLQESNEQTAALRKEVAALTDTSPAPH AVQQRMAKMLARAVDEVAEMQAEARAEADALIAAAEAEAQAAERKRDEVLADMAAQQEALEAEYRETKEK LDAELADMRAEAQAAIDEARRAAERECEQLLGDAKQGADHYRDTARRAVEEASAQRIKILEQLMSVYREL EDVPAALQAAYDEQQGSADDGVLAAVDGKVRAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3650 | - | - | 100% (244) | hypothetical protein MAV_3650 |
| M. avium 104 | MAV_1300 | - | 9e-72 | 56.00% (250) | hypothetical protein MAV_1300 |
| M. avium 104 | MAV_2345 | - | 1e-10 | 28.74% (247) | Wag31 protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1709 | - | 2e-39 | 38.91% (257) | coiled-coil structural protein |
| M. gilvum PYR-GCK | Mflv_2996 | - | 2e-09 | 28.02% (207) | DivIVA family protein |
| M. tuberculosis H37Rv | Rv1682 | - | 2e-39 | 38.91% (257) | coiled-coil structural protein |
| M. leprae Br4923 | MLBr_00922 | ag84 | 4e-09 | 23.86% (197) | immunogenic protein, antigen 84 |
| M. abscessus ATCC 19977 | MAB_1531c | - | 4e-51 | 42.44% (271) | hypothetical protein MAB_1531c |
| M. marinum M | MMAR_3185 | wag31 | 4e-09 | 27.09% (251) | secreted antigen Wag31 |
| M. smegmatis MC2 155 | MSMEG_4217 | - | 2e-10 | 27.45% (204) | DivIVA protein |
| M. thermoresistible (build 8) | TH_2373 | wag31 | 2e-10 | 29.23% (195) | CONSERVED HYPOTHETICAL PROTEIN WAG31 |
| M. ulcerans Agy99 | MUL_3493 | wag31 | 3e-09 | 27.09% (251) | secreted antigen Wag31 |
| M. vanbaalenii PYR-1 | Mvan_3515 | - | 2e-09 | 26.47% (204) | DivIVA family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2996|M.gilvum_PYR-GCK -------------------MPLTPADVHNVAFSKPPIGKRGYNEDEVDAF
Mvan_3515|M.vanbaalenii_PYR-1 -------------------MPLTPADVHNVAFSKPPIGKRGYNEDEVDAF
TH_2373|M.thermoresistible__bu -------------------MPLTPADVHNVAFSKPPIGKRGYNEDEVDAF
MSMEG_4217|M.smegmatis_MC2_155 -------------------MPLTPADVHNVAFSKPPIGKRGYNEDEVDAF
MMAR_3185|M.marinum_M -------------------MPLTPADVHNVAFSKPPIGKRGYNEDEVDAF
MUL_3493|M.ulcerans_Agy99 -------------------MPLTPADVHNVAFSKPPIGKRGYNEDEVDAF
MLBr_00922|M.leprae_Br4923 -------------------MPLTPADVHNVAFSKPPIGKRGYNEDEVDAF
Mb1709|M.bovis_AF2122/97 MLPQRPNCTKLFRPRRGVSERYRVTTAHNGSAPRFQRTRSGYDPVAVNHY
Rv1682|M.tuberculosis_H37Rv MLPQRPNCTKLFRPRRGVSERYRVTTAHNGSAPRFQRTRSGYDPVAVNHY
MAB_1531c|M.abscessus_ATCC_199 ----------------------MTTTTLNESTRNFTRTRNGYDPIEVNEY
MAV_3650|M.avium_104 --------------------------MITEPVKTFSRKFMGYDTTAVDAH
. . **: *: .
Mflv_2996|M.gilvum_PYR-GCK LDLVENELSRLIEENSDLRQR-------ISELDHELGQAR-AGGAAA---
Mvan_3515|M.vanbaalenii_PYR-1 LDLVENELSRLIEENSDLRQR-------VAELDQELSAAR-RGEGGV---
TH_2373|M.thermoresistible__bu LDLVENELARLIEENTDLRQR-------VAELDQELQAAR-AAAGGG---
MSMEG_4217|M.smegmatis_MC2_155 LDLVENELTRLIEENADLRQR-------VAELDQELAAAR-SGAGASS--
MMAR_3185|M.marinum_M LDLVENELTRLIEENSDLRQR-------IAELDQELAAG--AGGGAAVTA
MUL_3493|M.ulcerans_Agy99 LDLVENELTRLIEENSDLRQR-------IAELDQELAAG--AGGGAAVTA
MLBr_00922|M.leprae_Br4923 LDLVENELTQLIEENSDLRQR-------IEELDHELAAGGGTGAGPVIAV
Mb1709|M.bovis_AF2122/97 IAELVLRQQAQHCEIETLKA-------EIASLKDENAALKDTSPSAQAVT
Rv1682|M.tuberculosis_H37Rv IAELVLRQQAQHCEIETLKA-------EIASLKDENAALKDTSPSAQAVT
MAB_1531c|M.abscessus_ATCC_199 ISRLTIMHQSGLNDVETLKSRLEDATKQISSLKDEVTTLSDTSPSAHAMT
MAV_3650|M.avium_104 IEMLTAKQQLLIDDVESLRARLQESNEQTAALRKEVAALTDTSPAPHAVQ
: : : *: * .* . .
Mflv_2996|M.gilvum_PYR-GCK QPTQTIPAYEPEPEPAPE-PEPEPVYEAPAPAAQQAAPATEDQHLRAAKV
Mvan_3515|M.vanbaalenii_PYR-1 QATQTLPVYEPEPEPAPA-PEP--VYEA-APTPAPAAPVTEDQHLRAAKV
TH_2373|M.thermoresistible__bu QSTQAIPLYQPEPEPEPA-PQP-----------EQSTAVSEDQHLKAAKV
MSMEG_4217|M.smegmatis_MC2_155 QATSSIPLYEPEPEPAPAPPQP--VYEA---PAQPAAPQSEDTAVRAARV
MMAR_3185|M.marinum_M QPTQAMPVYEPEPEPAKP-AAP-----------VASAATNEEQAMKAARV
MUL_3493|M.ulcerans_Agy99 QPTQAMPVYEPEPEPAKP-AAP-----------VASAATNEEQAMKAARV
MLBr_00922|M.leprae_Br4923 QPTQALSTFEPELVSAKQ-APV-----------AAVAETAEELAMKATRV
Mb1709|M.bovis_AF2122/97 DRMAKMLRLAVDEVFQMQSEAR------AEAATLVSAARDEAEAVRTQKR
Rv1682|M.tuberculosis_H37Rv DRMAKMLRLAVDEVFQMQSEAR------AEAATLVSAARDEAEAVRTQKR
MAB_1531c|M.abscessus_ATCC_199 DRMAKMLRIAVDEVAEMQNEAR------TESAALIASAKADAEAMRTKHK
MAV_3650|M.avium_104 QRMAKMLARAVDEVAEMQAEAR------AEADALIAAAEAEAQAAERKRD
: : : : : . :
Mflv_2996|M.gilvum_PYR-GCK LSLAQDTADRLTSSAKAESEK---------MLADARAQADQLVTEARQTA
Mvan_3515|M.vanbaalenii_PYR-1 LSLAQDTADRLTSSAKAESEK---------MLSDARAQADQMVTEARQTA
TH_2373|M.thermoresistible__bu LSLAQDTADRLTSTAKAESEK---------MLADARAQADAMIAEARSTA
MSMEG_4217|M.smegmatis_MC2_155 LSLAQDTADRLTSTAKAEADK---------LLSDARAQAEAMVSDARQTA
MMAR_3185|M.marinum_M LSLAQDTADRLTSTAKAESDK---------MLSDARANADQILSEARHTA
MUL_3493|M.ulcerans_Agy99 LSLAQDTADRLTSTAKAESDK---------MLSDARANADQILSEARHTA
MLBr_00922|M.leprae_Br4923 LSLAQDTADQLTSTAKVESDK---------MLADARVNADQILGEARLTA
Mb1709|M.bovis_AF2122/97 EMLADMNARQRALESEHADVMRRAREEAEQLVAQATAEVERMRVIDARRR
Rv1682|M.tuberculosis_H37Rv EMLADMNARQRALESEHADVMRRAREEAEQLVAQATAEVERMRVIDARRR
MAB_1531c|M.abscessus_ATCC_199 ELLADMAARQSALETEYTEVMARAREEANQIVAQAVSESERLRAAEAKRR
MAV_3650|M.avium_104 EVLADMAAQQEALEAEYRETK-----------------------------
**: * : : ::
Mflv_2996|M.gilvum_PYR-GCK ETTVTEARQRADAMLADAQSRSETQLRQAQEKADALQADAERKHSEIMGT
Mvan_3515|M.vanbaalenii_PYR-1 ETTVAEARQRADAMLADAQNRSETQLRQAQEKADALQADAERKHSEIMGT
TH_2373|M.thermoresistible__bu ETTIADARQRSEAMLNDAKTRSEAQLRQAQEKADALQADAERKHSEIMGT
MSMEG_4217|M.smegmatis_MC2_155 ETTVSEARQRADAMLADAQTRSEAQLRQAQEKADALQADAERKHSEIMGT
MMAR_3185|M.marinum_M ETTVTEARQRADGMLADAQARSESQLRQAQEKADALQADAERKHSEIMGT
MUL_3493|M.ulcerans_Agy99 ETTVTEARQRADGMLADAQARSESQLRQAQEKADALQADAERKHSEIMGT
MLBr_00922|M.leprae_Br4923 EATVAEAQQRADAMLADAQTRSEVQSRQAQEKADALQAEAERKHSEIMGA
Mb1709|M.bovis_AF2122/97 EKAEQELDAEIIRLRTDAQFQIDDQLQATQQECEKRLGEAKIEADRRLHV
Rv1682|M.tuberculosis_H37Rv EKAEQELDAEIIRLRTDAQFQIDDQLQATQQECEKRLGEAKIEADRRLHV
MAB_1531c|M.abscessus_ATCC_199 EKAETELDEELTKLRTDTQSAVDEQRRSIQGECEKRLADAKDEADRRLRL
MAV_3650|M.avium_104 ----EKLDAELADMRAEAQAAIDEARRAAERECEQLLGDAKQGAD-----
. . : ::: : : : :.: .:*: .
Mflv_2996|M.gilvum_PYR-GCK INQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGTRGSAAPVDTGA
Mvan_3515|M.vanbaalenii_PYR-1 INQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQRGSAAPVDSGA
TH_2373|M.thermoresistible__bu INQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQRGSAAPVDSTA
MSMEG_4217|M.smegmatis_MC2_155 INQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQRGSAAPVDSSA
MMAR_3185|M.marinum_M INQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQRGSAAPVDS--
MUL_3493|M.ulcerans_Agy99 INQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQRGSAAPVDS--
MLBr_00922|M.leprae_Br4923 ISQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQRGSAAPVDS--
Mb1709|M.bovis_AF2122/97 ADEQIEHGLSEARRTLEEISQRRVGILEQLARIHAQLENIPALLESAR--
Rv1682|M.tuberculosis_H37Rv ADEQIEHGLSEARRTLEEISQRRVGILEQLARIHAQLENIPALLESAR--
MAB_1531c|M.abscessus_ATCC_199 ADEQIERRLDQARRSVEEIGQQRISILEQLMGVHGRLESIPSALESAYRD
MAV_3650|M.avium_104 ------HYRDTARRAVEEASAQRIKILEQLMSVYRELEDVPAALQAAY--
. .: * : * .* :
Mflv_2996|M.gilvum_PYR-GCK NND-GGVNQFNRGNN--------
Mvan_3515|M.vanbaalenii_PYR-1 NND-GGFNQFNRGNN--------
TH_2373|M.thermoresistible__bu NSDSGAFNQFTRGSN--------
MSMEG_4217|M.smegmatis_MC2_155 NSDASGFGQFNRGNN--------
MMAR_3185|M.marinum_M SADAGGFEQFNRGNN--------
MUL_3493|M.ulcerans_Agy99 SADAGGFEQFNRGNN--------
MLBr_00922|M.leprae_Br4923 NADAGGFDQFNRGNN--------
Mb1709|M.bovis_AF2122/97 HSETEPLQSING-AVAELRAI--
Rv1682|M.tuberculosis_H37Rv HSETEPLQSING-AVAELRAI--
MAB_1531c|M.abscessus_ATCC_199 RDNSKSIVMVPSKRVLDQKVIEG
MAV_3650|M.avium_104 -DEQQGSADDGVLAAVDGKVRAG
: