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MLIRRVARPMLSAVFISRGVEALRSPKPAADATRHTLEGLSKLPDPVGTNVPSNAETVAKVAAAVQIGGG LLLATGRLPRVASAALALSVVPSSLGGHAFWNEADPQRKADERRAFVTDISLIGGLIIAAVDTEGKPSLG WRGRRAAHKVSEAVAAALPAGAAAGGSLADSEFVEKVEHGLQVGAERGRELAHVARERGGELAHVARERA PVLAEAARERAETARERAAVLAELARERGPELAEAARERAEAARERAAMLADTAGTEVKKQKRRLR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3403 | - | - | 100% (276) | DoxX family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3130 | - | 1e-115 | 74.67% (304) | DoxX family protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4785 | - | 2e-38 | 37.40% (254) | hypothetical protein MAB_4785 |
| M. marinum M | MMAR_3017 | - | 1e-79 | 57.50% (280) | hypothetical protein MMAR_3017 |
| M. avium 104 | MAV_2471 | - | 2e-74 | 54.09% (281) | DoxX subfamily protein, putative |
| M. smegmatis MC2 155 | MSMEG_3255 | - | 1e-95 | 69.50% (259) | DoxX subfamily protein, putative |
| M. thermoresistible (build 8) | TH_4441 | - | 5e-39 | 75.25% (101) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2258 | - | 1e-80 | 57.86% (280) | hypothetical protein MUL_2258 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3403|M.vanbaalenii_PYR-1 MLIRRVARPMLSAVFISRGVEALRSPKPAADATRHTLEGLSKLPDPVGTN
Mflv_3130|M.gilvum_PYR-GCK MLIRRVARPMLSAVFISRGVDALRSPKPATDATRQTLEELSKLPDPVGTK
MSMEG_3255|M.smegmatis_MC2_155 ---------MLSATFIARGVDALRNPKPAADAARPTLGMMSSLPDPVGSK
MMAR_3017|M.marinum_M MLIRRIARPMLSAAFIGQGVESLLNPKPAAQAAAPAVAGLRTLPEPMGSR
MUL_2258|M.ulcerans_Agy99 MLIRRIARPMLSAAFIGQGVESLLNPKPAAQAAAPAVAGLRTLPEPMGSR
MAV_2471|M.avium_104 ------------MAFIGQGVNSLLNPKSAAEAAAPAVDGLQALPDPVSGN
MAB_4785|M.abscessus_ATCC_1997 ---------MLGSIFIVAGADGLTRPSASVAATEPLVSSLLEHTPESARR
TH_4441|M.thermoresistible__bu ---------MLSAVFIGRGVDAVRSPKPAADAARPTIEGLTKLPEPVGPR
** *.:.: *..:. *: : : . . .
Mvan_3403|M.vanbaalenii_PYR-1 --VPSNAETVAKVAAAVQIGGGLLLATGRLPRVASAALALSVVPSSLGGH
Mflv_3130|M.gilvum_PYR-GCK VPVPSNAETVAKVTAAVQIGGGLLLATGKLPRFASAALALSVVPGSLGGH
MSMEG_3255|M.smegmatis_MC2_155 --VPSDAETVAKINGAVQVVGGLLLASGKMPRLTAAALALSVVPGSLGSH
MMAR_3017|M.marinum_M --VPADPETVAQINAAVQIGGGLLLATGRLPRLASAALALTVVPGNLGAH
MUL_2258|M.ulcerans_Agy99 --VPADPETVAQINAAVQIGGGLLLATGRLPRLASAALALTVVPGNLGAH
MAV_2471|M.avium_104 --IPSDPETVAQITAAVQIGGGLLLATGKLPRVASAALALTVLPANLGAH
MAB_4785|M.abscessus_ATCC_1997 -YLPSDPQTYVRIHGATQLAAGLALASGKLPRISAWVLAGTLVPATLTDQ
TH_4441|M.thermoresistible__bu --VPTDAETVARINGMVQIAGGALLATGKLPRVASAVLALSVVPGSLGGH
:*::.:* .:: . .*: .* **:*::**.:: .** :::*..* :
Mvan_3403|M.vanbaalenii_PYR-1 AFWNEADPQRKADERRAFVTDISLIGGLIIAAVDTEGKPSLGWRGRRAAH
Mflv_3130|M.gilvum_PYR-GCK SFWNEVDPQRKAEERRAFITDVSLIGGLIIAAVDTEGKPSLGWRGRRAAR
MSMEG_3255|M.smegmatis_MC2_155 SFWKESDPQRSAQERREFLTDLSLIGGLIIAAADTEGKPSLAWRGRRAAH
MMAR_3017|M.marinum_M MFWNEPDPDRKAQKRREFLTDVSLLGGLIIASADTAGKPSLAWRGRRAAE
MUL_2258|M.ulcerans_Agy99 MFWNEPDPDRKAQKRREFLTDVSLLGGLIIASADTAGKPSLAWRGRRAAE
MAV_2471|M.avium_104 SFWNESDPVAKAQKRQQFLTDLSLLGGLLIASADTAGKPSLGWRGRRAAE
MAB_4785|M.abscessus_ATCC_1997 AYWRQTDPALKLQQKTHFWKNISILGGLIIAGIDTEGRPGLSWRARRAAR
TH_4441|M.thermoresistible__bu MFWTESDPQRKAXXXTGGYPPAGFPPPGGFGASYRFG-DAFNWAWSAFTR
:* : ** . .: :.. * .: * :.
Mvan_3403|M.vanbaalenii_PYR-1 KVSEAVAAALP-AGAAAGGSLADSEFVEKVEHGLQVGAERGRELAHVARE
Mflv_3130|M.gilvum_PYR-GCK KVSETVAAALP-AGAAAGSSLTDSAFAEKVGHGLHVGAERGRELAHVAGE
MSMEG_3255|M.smegmatis_MC2_155 KVTASVAAALP-AGAAASESIADSAVAEKLGHGLSVGAERGRELAEIARE
MMAR_3017|M.marinum_M QLSGAVSSALP-GSDDVRLES---ELGDKIVHGIQAGAERGRELASTAAE
MUL_2258|M.ulcerans_Agy99 KLSGAVSSALP-GSDDMRLES---ELGDKIVHGIQAGAERGRELASTAAE
MAV_2471|M.avium_104 RLSERVSSAWP-GSDDSGFEADLSELGERIAHGLQIGAERGRELASTAAE
MAB_4785|M.abscessus_ATCC_1997 DAVAAVTSALP-GVEQTSQSLG----AKTLELG-EATRERIPDLVEHARE
TH_4441|M.thermoresistible__bu HAAPLMLAALAYVAIIFALSFLFSLVLTAFTPGGATTVDPDSFFDMFGVG
: :* . . . * : : .
Mvan_3403|M.vanbaalenii_PYR-1 RGGELAHVARER-----------APVLAEAARER----AETARERAAVLA
Mflv_3130|M.gilvum_PYR-GCK RGSELAEVARERGGKWAEVAREHGGELAEIARERGAELAEVARDRSAVLA
MSMEG_3255|M.smegmatis_MC2_155 RAAELAHAAREH-----------APELAEAARER----SAHLAERGAVLA
MMAR_3017|M.marinum_M KSAPYAEAALER-----------GRELASTAAEKGAPLAEAARRRG----
MUL_2258|M.ulcerans_Agy99 KSAPYAEAALER-----------GRELASTAAEKGAPLAEAARRRG----
MAV_2471|M.avium_104 RGAPYAEAALER-----------GRELASTAAERGAPYAEAALERGRELA
MAB_4785|M.abscessus_ATCC_1997 RGAEIAETAQRR-----------GSQFAETASRRGSELAERLSERGSELA
TH_4441|M.thermoresistible__bu GTLTMVVGVILLLFVSGVITSAFLNGLLAIADGQQIELASFFRPRNVGSV
. . : * : : *
Mvan_3403|M.vanbaalenii_PYR-1 ELARERGPELAEAARER---------------------------------
Mflv_3130|M.gilvum_PYR-GCK ERARDRAPELADVARDRGTEWAELARDR----------------------
MSMEG_3255|M.smegmatis_MC2_155 DVARERGLEFADVAQKRGLEFADVARGRG---------------------
MMAR_3017|M.marinum_M --------------------------------------------------
MUL_2258|M.ulcerans_Agy99 --------------------------------------------------
MAV_2471|M.avium_104 STAAERGRPLAKKARKRGEELADEAAERAAYLAQKARKRSEELAEEAAER
MAB_4785|M.abscessus_ATCC_1997 S-------------------------------------------------
TH_4441|M.thermoresistible__bu VIATVIVGVLSYIGTALCVVPGLIVSLFAMFTTVAVVDRNLSPIDGILAS
Mvan_3403|M.vanbaalenii_PYR-1 --------------------------AEAARERAAMLADTAGTEVK----
Mflv_3130|M.gilvum_PYR-GCK --------------------------AELARERAAVLADTAGKEAKKVSK
MSMEG_3255|M.smegmatis_MC2_155 -----------------------AELAETAREAAPELAETARAHGNVLAN
MMAR_3017|M.marinum_M -----------------------ERLAHSARVRGAELAETARHQGTHLAD
MUL_2258|M.ulcerans_Agy99 -----------------------ERLAHSARVRGAELAETARHQGTQLAD
MAV_2471|M.avium_104 GKPLAKKARKRSEKLAKKARKRSEKLAGTARVRGEELAETARQRGSLLAD
MAB_4785|M.abscessus_ATCC_1997 -------------------------AAEKGRHQVEALAADPPPRVRRFVH
TH_4441|M.thermoresistible__bu VDVVKKNFGPAILVWLASG----VLIFLGSLLCGVGLLITGPLAGLLVVC
. *
Mvan_3403|M.vanbaalenii_PYR-1 -------KQKRRLR-----
Mflv_3130|M.gilvum_PYR-GCK EAKKQAKKQQRRVR-----
MSMEG_3255|M.smegmatis_MC2_155 RTRKQLKQARRR-------
MMAR_3017|M.marinum_M TARARVEAPVR-GRRH---
MUL_2258|M.ulcerans_Agy99 TARARVEAPVR-GRRH---
MAV_2471|M.avium_104 TARERVGGQVGTGRRKLSW
MAB_4785|M.abscessus_ATCC_1997 AFIRR--------------
TH_4441|M.thermoresistible__bu TFRRLTGAPVAPQAV----