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LIRRVARPMLSAVFISRGVDALRSPKPATDATRQTLEELSKLPDPVGTKVPVPSNAETVAKVTAAVQIGG GLLLATGKLPRFASAALALSVVPGSLGGHSFWNEVDPQRKAEERRAFITDVSLIGGLIIAAVDTEGKPSL GWRGRRAARKVSETVAAALPAGAAAGSSLTDSAFAEKVGHGLHVGAERGRELAHVAGERGSELAEVARER GGKWAEVAREHGGELAEIARERGAELAEVARDRSAVLAERARDRAPELADVARDRGTEWAELARDRAELA RERAAVLADTAGKEAKKVSKEAKKQAKKQQRRVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3130 | - | - | 100% (315) | DoxX family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | MLBr_01360 | recN | 3e-05 | 28.37% (208) | recombination and DNA repair |
| M. abscessus ATCC 19977 | MAB_4785 | - | 4e-41 | 37.60% (250) | hypothetical protein MAB_4785 |
| M. marinum M | MMAR_3017 | - | 2e-79 | 58.27% (266) | hypothetical protein MMAR_3017 |
| M. avium 104 | MAV_2471 | - | 1e-81 | 53.85% (299) | DoxX subfamily protein, putative |
| M. smegmatis MC2 155 | MSMEG_3255 | - | 2e-98 | 63.96% (308) | DoxX subfamily protein, putative |
| M. thermoresistible (build 8) | TH_4441 | - | 3e-37 | 73.79% (103) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2258 | - | 2e-80 | 58.65% (266) | hypothetical protein MUL_2258 |
| M. vanbaalenii PYR-1 | Mvan_3403 | - | 1e-115 | 72.70% (315) | DoxX family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3130|M.gilvum_PYR-GCK ----MLIRRVARPMLSAVFISRGVDALRSPK--------------PATDA
Mvan_3403|M.vanbaalenii_PYR-1 ----MLIRRVARPMLSAVFISRGVEALRSPK--------------PAADA
MSMEG_3255|M.smegmatis_MC2_155 -------------MLSATFIARGVDALRNPK--------------PAADA
MMAR_3017|M.marinum_M ----MLIRRIARPMLSAAFIGQGVESLLNPK--------------PAAQA
MUL_2258|M.ulcerans_Agy99 ----MLIRRIARPMLSAAFIGQGVESLLNPK--------------PAAQA
MAV_2471|M.avium_104 ----------------MAFIGQGVNSLLNPK--------------SAAEA
MAB_4785|M.abscessus_ATCC_1997 -------------MLGSIFIVAGADGLTRPS--------------ASVAA
TH_4441|M.thermoresistible__bu -------------MLSAVFIGRGVDAVRSPK--------------PAADA
MLBr_01360|M.leprae_Br4923 MLTEIRIESLGAISVATAEFDRGLTVLTGETGTGKTMVVTGLHLLGGARA
: * : . .. *
Mflv_3130|M.gilvum_PYR-GCK TRQTLEELSKLPDPVGTKVPVPSNAETVAKVTAAVQIGG-----------
Mvan_3403|M.vanbaalenii_PYR-1 TRHTLEGLSKLPDPVGTN--VPSNAETVAKVAAAVQIGG-----------
MSMEG_3255|M.smegmatis_MC2_155 ARPTLGMMSSLPDPVGSK--VPSDAETVAKINGAVQVVG-----------
MMAR_3017|M.marinum_M AAPAVAGLRTLPEPMGSR--VPADPETVAQINAAVQIGG-----------
MUL_2258|M.ulcerans_Agy99 AAPAVAGLRTLPEPMGSR--VPADPETVAQINAAVQIGG-----------
MAV_2471|M.avium_104 AAPAVDGLQALPDPVSGN--IPSDPETVAQITAAVQIGG-----------
MAB_4785|M.abscessus_ATCC_1997 TEPLVSSLLEHTPESARR-YLPSDPQTYVRIHGATQLAA-----------
TH_4441|M.thermoresistible__bu ARPTIEGLTKLPEPVGPR--VPTDAETVARINGMVQIAG-----------
MLBr_01360|M.leprae_Br4923 DASRVRSGANRAVVEGRFTTTDLDDVVVAQLDGILNASGSERDEDGSVIV
: . . : . .:: . : .
Mflv_3130|M.gilvum_PYR-GCK ---------------GLLLATGKLPRFASAALALS--------VVPGS--
Mvan_3403|M.vanbaalenii_PYR-1 ---------------GLLLATGRLPRVASAALALS--------VVPSS--
MSMEG_3255|M.smegmatis_MC2_155 ---------------GLLLASGKMPRLTAAALALS--------VVPGS--
MMAR_3017|M.marinum_M ---------------GLLLATGRLPRLASAALALT--------VVPGN--
MUL_2258|M.ulcerans_Agy99 ---------------GLLLATGRLPRLASAALALT--------VVPGN--
MAV_2471|M.avium_104 ---------------GLLLATGKLPRVASAALALT--------VLPAN--
MAB_4785|M.abscessus_ATCC_1997 ---------------GLALASGKLPRISAWVLAGT--------LVPAT--
TH_4441|M.thermoresistible__bu ---------------GALLATGKLPRVASAVLALS--------VVPGS--
MLBr_01360|M.leprae_Br4923 LRSVSRDGPSRSYLGGRSVPAKSLGSFTTELLALHGQNDQLRLVRPEEQR
* :.: : .:: ** : *
Mflv_3130|M.gilvum_PYR-GCK ------------------LGGHSFWNEVDPQRKAEERRAFITDVSLIGGL
Mvan_3403|M.vanbaalenii_PYR-1 ------------------LGGHAFWNEADPQRKADERRAFVTDISLIGGL
MSMEG_3255|M.smegmatis_MC2_155 ------------------LGSHSFWKESDPQRSAQERREFLTDLSLIGGL
MMAR_3017|M.marinum_M ------------------LGAHMFWNEPDPDRKAQKRREFLTDVSLLGGL
MUL_2258|M.ulcerans_Agy99 ------------------LGAHMFWNEPDPDRKAQKRREFLTDVSLLGGL
MAV_2471|M.avium_104 ------------------LGAHSFWNESDPVAKAQKRQQFLTDLSLLGGL
MAB_4785|M.abscessus_ATCC_1997 ------------------LTDQAYWRQTDPALKLQQKTHFWKNISILGGL
TH_4441|M.thermoresistible__bu ------------------LGGHMFWTESDPQRKAXXXTGGYPPAGFPPPG
MLBr_01360|M.leprae_Br4923 AALDRYAAAGPSCERYRELRDAWLLARSDLIDRRNRIRELVQEADRLKFA
* . * .
Mflv_3130|M.gilvum_PYR-GCK I--IAAVDTEGKPSLGWRG-----------RRAARKVSETVAAALP----
Mvan_3403|M.vanbaalenii_PYR-1 I--IAAVDTEGKPSLGWRG-----------RRAAHKVSEAVAAALP----
MSMEG_3255|M.smegmatis_MC2_155 I--IAAADTEGKPSLAWRG-----------RRAAHKVTASVAAALP----
MMAR_3017|M.marinum_M I--IASADTAGKPSLAWRG-----------RRAAEQLSGAVSSALP----
MUL_2258|M.ulcerans_Agy99 I--IASADTAGKPSLAWRG-----------RRAAEKLSGAVSSALP----
MAV_2471|M.avium_104 L--IASADTAGKPSLGWRG-----------RRAAERLSERVSSAWP----
MAB_4785|M.abscessus_ATCC_1997 I--IAGIDTEGRPGLSWRA-----------RRAARDAVAAVTSALP----
TH_4441|M.thermoresistible__bu G--FGASYRFG-DAFNWAW-----------SAFTRHAAPLMLAALAY---
MLBr_01360|M.leprae_Br4923 LSEIDSVDPQPGEDNALVADIVRLSELDMLREVAVNARAALSGALDDMDV
: . : : .*
Mflv_3130|M.gilvum_PYR-GCK -----------------AGAAAGSSLTDSAFAEKVGHGLHVGAERGRELA
Mvan_3403|M.vanbaalenii_PYR-1 -----------------AGAAAGGSLADSEFVEKVEHGLQVGAERGRELA
MSMEG_3255|M.smegmatis_MC2_155 -----------------AGAAASESIADSAVAEKLGHGLSVGAERGRELA
MMAR_3017|M.marinum_M -----------------GSDDVRLES---ELGDKIVHGIQAGAERGRELA
MUL_2258|M.ulcerans_Agy99 -----------------GSDDMRLES---ELGDKIVHGIQAGAERGRELA
MAV_2471|M.avium_104 -----------------GSDDSGFEADLSELGERIAHGLQIGAERGRELA
MAB_4785|M.abscessus_ATCC_1997 -----------------GVEQTSQSLG----AKTLELG-EATRERIPDLV
TH_4441|M.thermoresistible__bu -----------------VAIIFALSFLFSLVLTAFTPGGATTVDPDSFFD
MLBr_01360|M.leprae_Br4923 SGSNAVACMGQAKAALESTDDATLRAFADQVGEVLTVVVEVGRELGEYLE
. : :
Mflv_3130|M.gilvum_PYR-GCK HVAGERGSELAEVARERGGKWAE---------------------------
Mvan_3403|M.vanbaalenii_PYR-1 HVARERGGELAHVARER---------------------------------
MSMEG_3255|M.smegmatis_MC2_155 EIARERAAELAHAAREH---------------------------------
MMAR_3017|M.marinum_M STAAEKSAPYAEAALER---------------------------------
MUL_2258|M.ulcerans_Agy99 STAAEKSAPYAEAALER---------------------------------
MAV_2471|M.avium_104 STAAERGAPYAEAALER---------------------------------
MAB_4785|M.abscessus_ATCC_1997 EHARERGAEIAETAQRR---------------------------------
TH_4441|M.thermoresistible__bu MFGVGGTLTMVVGVILLLFVSGV---------------------------
MLBr_01360|M.leprae_Br4923 ELPVDASALESKLVRQAELCTLTRKYAADIDGVLQWARESRERLEQLDVS
.
Mflv_3130|M.gilvum_PYR-GCK -----VAREHGGELAEIARERGAELAEVARDRSAVLAERARDRAPELADV
Mvan_3403|M.vanbaalenii_PYR-1 ----------APVLAEAARER----AETARERAAVLAELARERGPELAEA
MSMEG_3255|M.smegmatis_MC2_155 ----------APELAEAARER----SAHLAERGAVLADVARERGLEFADV
MMAR_3017|M.marinum_M ----------GRELASTAAEKGAPLAEAARRRG-----------------
MUL_2258|M.ulcerans_Agy99 ----------GRELASTAAEKGAPLAEAARRRG-----------------
MAV_2471|M.avium_104 ----------GRELASTAAERGAPYAEAALERGRELASTAAERGRPLAKK
MAB_4785|M.abscessus_ATCC_1997 ----------GSQFAETASRRGSELAERLSERGSELAS------------
TH_4441|M.thermoresistible__bu -----ITSAFLNGLLAIADGQQIELASFFRPRNVGSVVIATVIVGVLSYI
MLBr_01360|M.leprae_Br4923 YERLAGVESRVDELERQLSQAAVDLSKLRRDAANRLAKEVTAELSALAMV
: :
Mflv_3130|M.gilvum_PYR-GCK ARDRGTEWAELAR-------------------------------------
Mvan_3403|M.vanbaalenii_PYR-1 AR------------------------------------------------
MSMEG_3255|M.smegmatis_MC2_155 AQKRGLEFADVARGRG----------------------------------
MMAR_3017|M.marinum_M --------------------------------------------------
MUL_2258|M.ulcerans_Agy99 --------------------------------------------------
MAV_2471|M.avium_104 ARKRGEELADEAAERAAYLAQKARKRSEELAEEAAER-------------
MAB_4785|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4441|M.thermoresistible__bu GTALCVVPGLIVSLFAMFTTVAVVDRNLSPIDGILAS-------------
MLBr_01360|M.leprae_Br4923 DAEFTISVTTDLIPLTDYKRSAAVTLPSGGVARAGADGVDQVEFGFAAHR
Mflv_3130|M.gilvum_PYR-GCK -------------------------DRAELARERAAVLADTAGKEAKKVS
Mvan_3403|M.vanbaalenii_PYR-1 -------------------------ERAEAARERAAMLADTAGTEVK---
MSMEG_3255|M.smegmatis_MC2_155 ------------------------AELAETAREAAPELAETARAHGNVLA
MMAR_3017|M.marinum_M ------------------------ERLAHSARVRGAELAETARHQGTHLA
MUL_2258|M.ulcerans_Agy99 ------------------------ERLAHSARVRGAELAETARHQGTQLA
MAV_2471|M.avium_104 -GKPLAKKARKRSEKLAKKARKRSEKLAGTARVRGEELAETARQRGSLLA
MAB_4785|M.abscessus_ATCC_1997 --------------------------AAEKGRHQVEALAADPPPRVRRFV
TH_4441|M.thermoresistible__bu -VDVVKKNFGPAILVWLASG----VLIFLGSLLCGVGLLITGPLAGLLVV
MLBr_01360|M.leprae_Br4923 GMTVLPLAKSASGGELSRVMLALEVVLATSAAGTTMVFDEVDVGVGGRAA
. :
Mflv_3130|M.gilvum_PYR-GCK KEAKKQAKKQQRRVR-----------------------------------
Mvan_3403|M.vanbaalenii_PYR-1 --------KQKRRLR-----------------------------------
MSMEG_3255|M.smegmatis_MC2_155 NRTRKQLKQARRR-------------------------------------
MMAR_3017|M.marinum_M DTARARVEAPVR-GRRH---------------------------------
MUL_2258|M.ulcerans_Agy99 DTARARVEAPVR-GRRH---------------------------------
MAV_2471|M.avium_104 DTARERVGGQVGTGRRKLSW------------------------------
MAB_4785|M.abscessus_ATCC_1997 HAFIRR--------------------------------------------
TH_4441|M.thermoresistible__bu CTFRRLTGAPVAPQAV----------------------------------
MLBr_01360|M.leprae_Br4923 VQIGRRLARLARTHQVIVVTHLPQVAAYADVHLVVHSAGLDGASDVRRLA
Mflv_3130|M.gilvum_PYR-GCK -------------------------------------
Mvan_3403|M.vanbaalenii_PYR-1 -------------------------------------
MSMEG_3255|M.smegmatis_MC2_155 -------------------------------------
MMAR_3017|M.marinum_M -------------------------------------
MUL_2258|M.ulcerans_Agy99 -------------------------------------
MAV_2471|M.avium_104 -------------------------------------
MAB_4785|M.abscessus_ATCC_1997 -------------------------------------
TH_4441|M.thermoresistible__bu -------------------------------------
MLBr_01360|M.leprae_Br4923 GDDRVAELARMLAGLGESDSGRAHARELLDAARKDKS