For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_3255 (-)

annotation: DoxX subfamily protein, putative
coordinates: 3336777 - 3337652
length: 291

LSATFIARGVDALRNPKPAADAARPTLGMMSSLPDPVGSKVPSDAETVAKINGAVQVVGGLLLASGKMPR
LTAAALALSVVPGSLGSHSFWKESDPQRSAQERREFLTDLSLIGGLIIAAADTEGKPSLAWRGRRAAHKV
TASVAAALPAGAAASESIADSAVAEKLGHGLSVGAERGRELAEIARERAAELAHAAREHAPELAEAARER
SAHLAERGAVLADVARERGLEFADVAQKRGLEFADVARGRGAELAETAREAAPELAETARAHGNVLANRT
RKQLKQARRR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3255--100% (291)DoxX subfamily protein, putative

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_3130-2e-9863.96% (308) DoxX family protein
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4785-8e-4435.79% (271) hypothetical protein MAB_4785
M. marinum MMMAR_3017-2e-7755.68% (273) hypothetical protein MMAR_3017
M. avium 104MAV_2471-4e-7853.40% (294) DoxX subfamily protein, putative
M. thermoresistible (build 8)TH_4441-4e-3871.29% (101) PUTATIVE putative conserved hypothetical protein
M. ulcerans Agy99MUL_2258-3e-7856.04% (273) hypothetical protein MUL_2258
M. vanbaalenii PYR-1Mvan_3403-1e-9569.50% (259) DoxX family protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3130|M.gilvum_PYR-GCK          MLIRRVARPMLSAVFISRGVDALRSPKPATDATRQTLEELSKLPDPVGTK
Mvan_3403|M.vanbaalenii_PYR-1       MLIRRVARPMLSAVFISRGVEALRSPKPAADATRHTLEGLSKLPDPVGTN
MSMEG_3255|M.smegmatis_MC2_155      ---------MLSATFIARGVDALRNPKPAADAARPTLGMMSSLPDPVGSK
MMAR_3017|M.marinum_M               MLIRRIARPMLSAAFIGQGVESLLNPKPAAQAAAPAVAGLRTLPEPMGSR
MUL_2258|M.ulcerans_Agy99           MLIRRIARPMLSAAFIGQGVESLLNPKPAAQAAAPAVAGLRTLPEPMGSR
MAV_2471|M.avium_104                ------------MAFIGQGVNSLLNPKSAAEAAAPAVDGLQALPDPVSGN
MAB_4785|M.abscessus_ATCC_1997      ---------MLGSIFIVAGADGLTRPSASVAATEPLVSSLLEHTPESARR
TH_4441|M.thermoresistible__bu      ---------MLSAVFIGRGVDAVRSPKPAADAARPTIEGLTKLPEPVGPR
                                                  **  *.:.:  *..:. *:   :  :   .   . .

Mflv_3130|M.gilvum_PYR-GCK          VPVPSNAETVAKVTAAVQIGGGLLLATGKLPRFASAALALSVVPGSLGGH
Mvan_3403|M.vanbaalenii_PYR-1       --VPSNAETVAKVAAAVQIGGGLLLATGRLPRVASAALALSVVPSSLGGH
MSMEG_3255|M.smegmatis_MC2_155      --VPSDAETVAKINGAVQVVGGLLLASGKMPRLTAAALALSVVPGSLGSH
MMAR_3017|M.marinum_M               --VPADPETVAQINAAVQIGGGLLLATGRLPRLASAALALTVVPGNLGAH
MUL_2258|M.ulcerans_Agy99           --VPADPETVAQINAAVQIGGGLLLATGRLPRLASAALALTVVPGNLGAH
MAV_2471|M.avium_104                --IPSDPETVAQITAAVQIGGGLLLATGKLPRVASAALALTVLPANLGAH
MAB_4785|M.abscessus_ATCC_1997      -YLPSDPQTYVRIHGATQLAAGLALASGKLPRISAWVLAGTLVPATLTDQ
TH_4441|M.thermoresistible__bu      --VPTDAETVARINGMVQIAGGALLATGKLPRVASAVLALSVVPGSLGGH
                                      :*::.:* .:: . .*: .*  **:*::**.:: .** :::*..*  :

Mflv_3130|M.gilvum_PYR-GCK          SFWNEVDPQRKAEERRAFITDVSLIGGLIIAAVDTEGKPSLGWRGRRAAR
Mvan_3403|M.vanbaalenii_PYR-1       AFWNEADPQRKADERRAFVTDISLIGGLIIAAVDTEGKPSLGWRGRRAAH
MSMEG_3255|M.smegmatis_MC2_155      SFWKESDPQRSAQERREFLTDLSLIGGLIIAAADTEGKPSLAWRGRRAAH
MMAR_3017|M.marinum_M               MFWNEPDPDRKAQKRREFLTDVSLLGGLIIASADTAGKPSLAWRGRRAAE
MUL_2258|M.ulcerans_Agy99           MFWNEPDPDRKAQKRREFLTDVSLLGGLIIASADTAGKPSLAWRGRRAAE
MAV_2471|M.avium_104                SFWNESDPVAKAQKRQQFLTDLSLLGGLLIASADTAGKPSLGWRGRRAAE
MAB_4785|M.abscessus_ATCC_1997      AYWRQTDPALKLQQKTHFWKNISILGGLIIAGIDTEGRPGLSWRARRAAR
TH_4441|M.thermoresistible__bu      MFWTESDPQRKAXXXTGGYPPAGFPPPGGFGASYRFG-DAFNWAWSAFTR
                                     :* : **  .           .:     :..    *  .: *     :.

Mflv_3130|M.gilvum_PYR-GCK          KVSETVAAALP-AGAAAGSSLTDSAFAEKVGHGLHVGAERGRELAHVAGE
Mvan_3403|M.vanbaalenii_PYR-1       KVSEAVAAALP-AGAAAGGSLADSEFVEKVEHGLQVGAERGRELAHVARE
MSMEG_3255|M.smegmatis_MC2_155      KVTASVAAALP-AGAAASESIADSAVAEKLGHGLSVGAERGRELAEIARE
MMAR_3017|M.marinum_M               QLSGAVSSALP-GSDDVRLES---ELGDKIVHGIQAGAERGRELASTAAE
MUL_2258|M.ulcerans_Agy99           KLSGAVSSALP-GSDDMRLES---ELGDKIVHGIQAGAERGRELASTAAE
MAV_2471|M.avium_104                RLSERVSSAWP-GSDDSGFEADLSELGERIAHGLQIGAERGRELASTAAE
MAB_4785|M.abscessus_ATCC_1997      DAVAAVTSALP-GVEQTSQSLG----AKTLELG-EATRERIPDLVEHARE
TH_4441|M.thermoresistible__bu      HAAPLMLAALAYVAIIFALSFLFSLVLTAFTPGGATTVDPDSFFDMFGVG
                                         : :* .        .         .  *     :    :   .  

Mflv_3130|M.gilvum_PYR-GCK          RGSELAEVARERGGKWAEVAREHGGELAEIARERGAELAEVARDRSAVLA
Mvan_3403|M.vanbaalenii_PYR-1       RGGELAHVARER-----------APVLAEAARER----AETARERAAVLA
MSMEG_3255|M.smegmatis_MC2_155      RAAELAHAAREH-----------APELAEAARER----SAHLAERGAVLA
MMAR_3017|M.marinum_M               KSAPYAEAALER-----------GRELASTAAEKGAPLAEAARRRG----
MUL_2258|M.ulcerans_Agy99           KSAPYAEAALER-----------GRELASTAAEKGAPLAEAARRRG----
MAV_2471|M.avium_104                RGAPYAEAALER-----------GRELASTAAERGAPYAEAALERGRELA
MAB_4785|M.abscessus_ATCC_1997      RGAEIAETAQRR-----------GSQFAETASRRGSELAERLSERGSELA
TH_4441|M.thermoresistible__bu      GTLTMVVGVILLLFVSGVITSAFLNGLLAIADGQQIELASFFRPRNVGSV
                                         .  .                 :   *  :    :     *     

Mflv_3130|M.gilvum_PYR-GCK          ERARDRAPELADVARDRGTEWAELAR------------------------
Mvan_3403|M.vanbaalenii_PYR-1       ELARERGPELAEAAR-----------------------------------
MSMEG_3255|M.smegmatis_MC2_155      DVARERGLEFADVAQKRGLEFADVARGRG---------------------
MMAR_3017|M.marinum_M               --------------------------------------------------
MUL_2258|M.ulcerans_Agy99           --------------------------------------------------
MAV_2471|M.avium_104                STAAERGRPLAKKARKRGEELADEAAERAAYLAQKARKRSEELAEEAAER
MAB_4785|M.abscessus_ATCC_1997      S-------------------------------------------------
TH_4441|M.thermoresistible__bu      VIATVIVGVLSYIGTALCVVPGLIVSLFAMFTTVAVVDRNLSPIDGILAS
                                                                                      

Mflv_3130|M.gilvum_PYR-GCK          ------------------------DRAELARERAAVLADTAGKEAKKVSK
Mvan_3403|M.vanbaalenii_PYR-1       ------------------------ERAEAARERAAMLADTAGTEVK----
MSMEG_3255|M.smegmatis_MC2_155      -----------------------AELAETAREAAPELAETARAHGNVLAN
MMAR_3017|M.marinum_M               -----------------------ERLAHSARVRGAELAETARHQGTHLAD
MUL_2258|M.ulcerans_Agy99           -----------------------ERLAHSARVRGAELAETARHQGTQLAD
MAV_2471|M.avium_104                GKPLAKKARKRSEKLAKKARKRSEKLAGTARVRGEELAETARQRGSLLAD
MAB_4785|M.abscessus_ATCC_1997      -------------------------AAEKGRHQVEALAADPPPRVRRFVH
TH_4441|M.thermoresistible__bu      VDVVKKNFGPAILVWLASG----VLIFLGSLLCGVGLLITGPLAGLLVVC
                                                                 .      *             

Mflv_3130|M.gilvum_PYR-GCK          EAKKQAKKQQRRVR-----
Mvan_3403|M.vanbaalenii_PYR-1       -------KQKRRLR-----
MSMEG_3255|M.smegmatis_MC2_155      RTRKQLKQARRR-------
MMAR_3017|M.marinum_M               TARARVEAPVR-GRRH---
MUL_2258|M.ulcerans_Agy99           TARARVEAPVR-GRRH---
MAV_2471|M.avium_104                TARERVGGQVGTGRRKLSW
MAB_4785|M.abscessus_ATCC_1997      AFIRR--------------
TH_4441|M.thermoresistible__bu      TFRRLTGAPVAPQAV----