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IHDAFGYGRDKQSINDRIARAGYLALTPNMYARGGLVRCITRVMKELAAQRGRALDDILAARDHLQAMPE CTGRVGIAGFCMGGRFALVMSPKGFGASAPFYGTPLPGNLDEVLEGACPVVASFGGRDLTGKGAPEKLRK VTADKNITADIKVYPEAGHSFANELPAQPLLRIAGFGYNEEATEDAWRRVFSFFGEHLAATP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2443 | - | - | 100% (203) | dienelactone hydrolase family protein |
| M. avium 104 | MAV_0487 | - | 4e-46 | 44.12% (204) | dienelactone hydrolase family protein |
| M. avium 104 | MAV_3654 | - | 8e-07 | 31.50% (127) | hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2080 | - | 6e-88 | 75.62% (201) | hypothetical protein Mb2080 |
| M. gilvum PYR-GCK | Mflv_3311 | - | 2e-10 | 26.34% (205) | dienelactone hydrolase |
| M. tuberculosis H37Rv | Rv2054 | - | 6e-88 | 75.62% (201) | hypothetical protein Rv2054 |
| M. leprae Br4923 | MLBr_01444 | - | 3e-86 | 72.86% (199) | putative dienelactone hydrolase |
| M. abscessus ATCC 19977 | MAB_3265c | - | 1e-11 | 28.50% (207) | hypothetical protein MAB_3265c |
| M. marinum M | MMAR_3032 | - | 9e-88 | 75.12% (201) | hypothetical protein MMAR_3032 |
| M. smegmatis MC2 155 | MSMEG_2444 | - | 5e-83 | 68.84% (199) | dienelactone hydrolase family protein |
| M. thermoresistible (build 8) | TH_0693 | - | 1e-10 | 28.57% (231) | PROBABLE ALANINE RICH HYDROLASE |
| M. ulcerans Agy99 | MUL_2272 | - | 2e-87 | 74.63% (201) | hypothetical protein MUL_2272 |
| M. vanbaalenii PYR-1 | Mvan_2379 | - | 7e-10 | 28.76% (226) | dienelactone hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2080|M.bovis_AF2122/97 --------------------------------------------------
Rv2054|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3032|M.marinum_M --------------------------------------------------
MUL_2272|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01444|M.leprae_Br4923 --------------------------------------------------
MSMEG_2444|M.smegmatis_MC2_155 --------------------------------------------------
MAV_2443|M.avium_104 --------------------------------------------------
TH_0693|M.thermoresistible__bu --------------------------------------------------
Mvan_2379|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3311|M.gilvum_PYR-GCK MTPLQRYIAEEIATDHVDGLMSRREALRRLALLGVGGAAATALIAACGQN
MAB_3265c|M.abscessus_ATCC_199 MTPLQRYIAEEIATDHIEGLLTRREAFRRLALLGVGATAAGALISACGTG
Mb2080|M.bovis_AF2122/97 -----------------------------MTTIEIDAPAGPIDALLGLPP
Rv2054|M.tuberculosis_H37Rv -----------------------------MTTIEIDAPAGPIDALLGLPP
MMAR_3032|M.marinum_M -----MTPTYGNCARVPRTVATRLQLDDAMTTIDIDTPAGPIDALLGVPT
MUL_2272|M.ulcerans_Agy99 -----------------------------MTTIDIDTPAGPIDALLGVPT
MLBr_01444|M.leprae_Br4923 -----------------------------MTKIQIDAPDGPIDALLSVPP
MSMEG_2444|M.smegmatis_MC2_155 ------------------------------MTITISTPDGPIDALLSTPT
MAV_2443|M.avium_104 --------------------------------------------------
TH_0693|M.thermoresistible__bu -------------------------------------------VTLHTPD
Mvan_2379|M.vanbaalenii_PYR-1 ---------------------------MPRITDTVTTADGDCPVSLHTPD
Mflv_3311|M.gilvum_PYR-GCK QQSAETTAEPSPTSDTPTSDAPPPGMDAALPTEPVTWAGPKGELQGAWAQ
MAB_3265c|M.abscessus_ATCC_199 NK---PVAAPAPAN----SGAPPPGMDNVVVTEPITWRGPNGTLQGAWAT
Mb2080|M.bovis_AF2122/97 GQGPWPGVVVVHDAVGYVPDNKLISERIARAGYVVLTPNMYARGGRAR--
Rv2054|M.tuberculosis_H37Rv GQGPWPGVVVVHDAVGYVPDNKLISERIARAGYVVLTPNMYARGGRAR--
MMAR_3032|M.marinum_M GEGPWPGVVVVHDAIGYAPDNEAISERIAAAGYLALTPNMYARGGRAR--
MUL_2272|M.ulcerans_Agy99 GEGPWPGVVVVHDAIGYAPDNEAISERIAAAGYLALTPNMYARGGRAR--
MLBr_01444|M.leprae_Br4923 GPEPWPGVVVIHDAIGYEPDKESTNNHIAMAGYVAITPNLYSRGSRAR--
MSMEG_2444|M.smegmatis_MC2_155 GSGPWPGVVIIHDAIGYGPDNELVSERVAQAGYLAITPNLYSRGGRAR--
MAV_2443|M.avium_104 ---------MIHDAFGYGRDKQSINDRIARAGYLALTPNMYARGGLVR--
TH_0693|M.thermoresistible__bu GAGPWPGVVLFVDAGGTRDLMREMADRLAGYGYAVLVPDVYYRHGRWEPF
Mvan_2379|M.vanbaalenii_PYR-1 GGGPWRGIVMYPDAGGARPTFRAMADKLAGYGYAVLVPDVYYREGDWAPF
Mflv_3311|M.gilvum_PYR-GCK AAEPRGGILVIHENKGLNDWTRSVAGRLAGAGYSSLAIDLLSERGGTATF
MAB_3265c|M.abscessus_ATCC_199 AAEPRGTVLVIHENKGLNDWVRSVAGRLAGVGYSSLAIDLLSEEGGASAF
: : * . ::* ** :. :: . .
Mb2080|M.bovis_AF2122/97 CITRVFRELLTKR-----------GRALDDILAARDHLLAMPECSG-RVG
Rv2054|M.tuberculosis_H37Rv CITRVFRELLTKR-----------GRALDDILAARDHLLAMPECSG-RVG
MMAR_3032|M.marinum_M CITRVFRELLTKR-----------GRALDDILAARDHLLAMAECSG-QVG
MUL_2272|M.ulcerans_Agy99 CITRVFRELLTKR-----------GRALDDILAARDHLLAMAECSG-QVG
MLBr_01444|M.leprae_Br4923 CITRVMRELLTKR-----------GRAFDDILATRDYLLAMPKCSG-RVG
MSMEG_2444|M.smegmatis_MC2_155 CITRMFRDLLTQR-----------GRALDDILAARDHLKSLPECTG-TVG
MAV_2443|M.avium_104 CITRVMKELAAQR-----------GRALDDILAARDHLQAMPECTG-RVG
TH_0693|M.thermoresistible__bu DMRTVFGDPSERARLYRMIRSITPDMMETDARAFFDFLQSRPEVKGDRFG
Mvan_2379|M.vanbaalenii_PYR-1 TIATAFDDDVERRRLFSFMAKVTPEVMAADATAFFDYLAGRPEVRGDTFG
Mflv_3311|M.gilvum_PYR-GCK ADPAEATAALGARTP---------EDMVADLRSGIAEVQRRTPDKK--VA
MAB_3265c|M.abscessus_ATCC_199 KDPAEATGTLGRIAP---------ERFIADLKSGVDEILRRVPGKP--AG
* : : .
Mb2080|M.bovis_AF2122/97 IVGFCMGGQFALVLS---PRGFGATAPFYG------TPLPRHLSETLNGA
Rv2054|M.tuberculosis_H37Rv IVGFCMGGQFALVLS---PRGFGATAPFYG------TPLPRHLSETLNGA
MMAR_3032|M.marinum_M IAGFCMGGQFALILS---PRGFGASAPFYG------TPLPRHLSETLDGA
MUL_2272|M.ulcerans_Agy99 IAGFCMGGQFALILS---PRGFGASAPFYG------TPLPRHLSETLDGA
MLBr_01444|M.leprae_Br4923 IAGFCMGGRFALVMS---PKGFDASAPFYG------TPLPRNLSETLNGA
MSMEG_2444|M.smegmatis_MC2_155 VVGFCSGGQFALIMG---PKGFAASAPFYG------TPLPRHLDRTLDAS
MAV_2443|M.avium_104 IAGFCMGGRFALVMS---PKGFGASAPFYG------TPLPGNLDEVLEGA
TH_0693|M.thermoresistible__bu VFGYCMGGRMSVTVAGRVPDRVAAAASFHAAGLVTDDPTSPHLLAERIKA
Mvan_2379|M.vanbaalenii_PYR-1 TTGYCMGGRTSLVLAGRLPDRVSAAMSFHGGGLATDDPHSPHLLADQMRA
Mflv_3311|M.gilvum_PYR-GCK AIGFCMGGGLVWRLLAAGTPELAAAFPFYG-------PTPEAPDFAGSRD
MAB_3265c|M.abscessus_ATCC_199 AVGFCFGGGLVWQLLAAGEPRLAAAAPFYG-------PLPDNPDFSRSK-
*:* ** : . *: .*:. * .
Mb2080|M.bovis_AF2122/97 CPIVASFGTRDPLGIGAANRLRKVTAAKNIPADIKSYPGAGHSFANKLPG
Rv2054|M.tuberculosis_H37Rv CPIVASFGTRDPLGIGAANRLRKVTAAKNIPADIKSYPGAGHSFANKLPG
MMAR_3032|M.marinum_M CPIVASFGNRDPLGLGAPSRLREVTQAKQIPADIKGYPGAGHSFANKLPR
MUL_2272|M.ulcerans_Agy99 CPIVASFGNRDPLGLGAPSRLREVTQAKQIPADIEGYPGAGHSFANKLPR
MLBr_01444|M.leprae_Br4923 CPIVASFGGRDPLGIGAPKRLRQATQTRHITTDIKVYPDAGHSFANKLPG
MSMEG_2444|M.smegmatis_MC2_155 CPIVASFGRRDPLGIGAPARLRRVVEAKNIPADIKVYPSAGHSFANILPA
MAV_2443|M.avium_104 CPVVASFGGRDLTGKGAPEKLRKVTADKNITADIKVYPEAGHSFANELPA
TH_0693|M.thermoresistible__bu TVYVAGAQDDDGFTPAHAETLGKALTDAGVEHTIEFYP-AGHGFAVPDNL
Mvan_2379|M.vanbaalenii_PYR-1 AVYVGAARSDRSFTTEDGERLEKALTSTGVEHTIEWYP-AFHGFAVPDNG
Mflv_3311|M.gilvum_PYR-GCK VAVLAFYGELDQRVNATEPDARAALEKAGLVHEIVIEPGANHAFFNDTGD
MAB_3265c|M.abscessus_ATCC_199 AAVLAFYGELDERVTASKDQAADALRRGGLLHEIAVEPGADHAFFNDSGP
:. . : * * * *.*
Mb2080|M.bovis_AF2122/97 QPLVRIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGEP
Rv2054|M.tuberculosis_H37Rv QPLVRIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGEP
MMAR_3032|M.marinum_M QPLLRITGFGYNEAATEDAWGRVFAFFGEHLAAGTSRG-
MUL_2272|M.ulcerans_Agy99 QPLLRITGFGYNEAATEDAWGRVFAFFGEHLAAGTSGN-
MLBr_01444|M.leprae_Br4923 QPLMRITGFGYNQAATEDAWSRVFAFFDKHLRTD-----
MSMEG_2444|M.smegmatis_MC2_155 QPLLRVTGFGYDEAATTDAWTRVFAFFDEHLKPKTAGQA
MAV_2443|M.avium_104 QPLLRIAGFGYNEEATEDAWRRVFSFFGEHLAATP----
TH_0693|M.thermoresistible__bu P---------YDEQAAERHWDALRALFDRELSG------
Mvan_2379|M.vanbaalenii_PYR-1 P---------YDEPAARRHWEAMRSFFATHLV-------
Mflv_3311|M.gilvum_PYR-GCK R---------YDPAAAADAWERTLAWLTAHVG-------
MAB_3265c|M.abscessus_ATCC_199 R---------YNASAAVDAWQRLLGWLGQHIG-------
*: *: * : .: