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MTTIEIDAPAGPIDALLGLPPGQGPWPGVVVVHDAVGYVPDNKLISERIARAGYVVLTPNMYARGGRARC ITRVFRELLTKRGRALDDILAARDHLLAMPECSGRVGIVGFCMGGQFALVLSPRGFGATAPFYGTPLPRH LSETLNGACPIVASFGTRDPLGIGAANRLRKVTAAKNIPADIKSYPGAGHSFANKLPGQPLVRIAGFGYN EAATEDAWRRVFEFFGQHLRAGSPGEP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv2054 | - | - | 100% (237) | hypothetical protein Rv2054 |
| M. tuberculosis H37Rv | Rv2765 | - | 5e-16 | 30.31% (254) | hypothetical protein Rv2765 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2080 | - | 1e-139 | 100.00% (237) | hypothetical protein Mb2080 |
| M. gilvum PYR-GCK | Mflv_4008 | - | 6e-15 | 28.34% (247) | dienelactone hydrolase |
| M. leprae Br4923 | MLBr_01444 | - | 1e-105 | 76.09% (230) | putative dienelactone hydrolase |
| M. abscessus ATCC 19977 | MAB_3183c | - | 5e-12 | 28.57% (252) | dienelactone hydrolase |
| M. marinum M | MMAR_3032 | - | 1e-118 | 85.41% (233) | hypothetical protein MMAR_3032 |
| M. avium 104 | MAV_2443 | - | 9e-88 | 75.62% (201) | dienelactone hydrolase family protein |
| M. smegmatis MC2 155 | MSMEG_2444 | - | 1e-103 | 71.37% (234) | dienelactone hydrolase family protein |
| M. thermoresistible (build 8) | TH_0693 | - | 2e-15 | 29.51% (244) | PROBABLE ALANINE RICH HYDROLASE |
| M. ulcerans Agy99 | MUL_2272 | - | 1e-119 | 84.68% (235) | hypothetical protein MUL_2272 |
| M. vanbaalenii PYR-1 | Mvan_2379 | - | 2e-16 | 29.84% (258) | dienelactone hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv2054|M.tuberculosis_H37Rv ------------------------MTTIEIDAPAGPIDALLGLPPGQGPW
Mb2080|M.bovis_AF2122/97 ------------------------MTTIEIDAPAGPIDALLGLPPGQGPW
MMAR_3032|M.marinum_M MTPTYGNCARVPRTVATRLQLDDAMTTIDIDTPAGPIDALLGVPTGEGPW
MUL_2272|M.ulcerans_Agy99 ------------------------MTTIDIDTPAGPIDALLGVPTGEGPW
MLBr_01444|M.leprae_Br4923 ------------------------MTKIQIDAPDGPIDALLSVPPGPEPW
MAV_2443|M.avium_104 --------------------------------------------------
MSMEG_2444|M.smegmatis_MC2_155 -------------------------MTITISTPDGPIDALLSTPTGSGPW
Mflv_4008|M.gilvum_PYR-GCK ----------------------MPTITDTVTTTDGSCPVTLHTPDGDGPW
Mvan_2379|M.vanbaalenii_PYR-1 ----------------------MPRITDTVTTADGDCPVSLHTPDGGGPW
TH_0693|M.thermoresistible__bu --------------------------------------VTLHTPDGAGPW
MAB_3183c|M.abscessus_ATCC_199 ----------------------MQRRDAQILTPDGLCSATLHLPDQPGP-
Rv2054|M.tuberculosis_H37Rv PGVVVVHDAVGYVPDNKLISERIARAGYVVLTPNMYARGG--RARCITRV
Mb2080|M.bovis_AF2122/97 PGVVVVHDAVGYVPDNKLISERIARAGYVVLTPNMYARGG--RARCITRV
MMAR_3032|M.marinum_M PGVVVVHDAIGYAPDNEAISERIAAAGYLALTPNMYARGG--RARCITRV
MUL_2272|M.ulcerans_Agy99 PGVVVVHDAIGYAPDNEAISERIAAAGYLALTPNMYARGG--RARCITRV
MLBr_01444|M.leprae_Br4923 PGVVVIHDAIGYEPDKESTNNHIAMAGYVAITPNLYSRGS--RARCITRV
MAV_2443|M.avium_104 ----MIHDAFGYGRDKQSINDRIARAGYLALTPNMYARGG--LVRCITRV
MSMEG_2444|M.smegmatis_MC2_155 PGVVIIHDAIGYGPDNELVSERVAQAGYLAITPNLYSRGG--RARCITRM
Mflv_4008|M.gilvum_PYR-GCK RGIVMYPDAGGVRPTFRTMADQLAGHGYAVLLPDVYYREGDWAPFTMSTV
Mvan_2379|M.vanbaalenii_PYR-1 RGIVMYPDAGGARPTFRAMADKLAGYGYAVLVPDVYYREGDWAPFTIATA
TH_0693|M.thermoresistible__bu PGVVLFVDAGGTRDLMREMADRLAGYGYAVLVPDVYYRHGRWEPFDMRTV
MAB_3183c|M.abscessus_ATCC_199 -AVVLYPDAGGARDVMRAMGDRLASWGYVVLVPDVYYREGNWQPFNMATA
: ** * . :::* ** .: *::* * . :
Rv2054|M.tuberculosis_H37Rv FRELLTKR-----------GRALDDILAARDHLLAMPECSG-RVGIVGFC
Mb2080|M.bovis_AF2122/97 FRELLTKR-----------GRALDDILAARDHLLAMPECSG-RVGIVGFC
MMAR_3032|M.marinum_M FRELLTKR-----------GRALDDILAARDHLLAMAECSG-QVGIAGFC
MUL_2272|M.ulcerans_Agy99 FRELLTKR-----------GRALDDILAARDHLLAMAECSG-QVGIAGFC
MLBr_01444|M.leprae_Br4923 MRELLTKR-----------GRAFDDILATRDYLLAMPKCSG-RVGIAGFC
MAV_2443|M.avium_104 MKELAAQR-----------GRALDDILAARDHLQAMPECTG-RVGIAGFC
MSMEG_2444|M.smegmatis_MC2_155 FRDLLTQR-----------GRALDDILAARDHLKSLPECTG-TVGVVGFC
Mflv_4008|M.gilvum_PYR-GCK FGDAAERRRLFGMISKVTPERMESDAVAFFDYLADRPEVSGETFGTTGYC
Mvan_2379|M.vanbaalenii_PYR-1 FDDDVERRRLFSFMAKVTPEVMAADATAFFDYLAGRPEVRGDTFGTTGYC
TH_0693|M.thermoresistible__bu FGDPSERARLYRMIRSITPDMMETDARAFFDFLQSRPEVKGDRFGVFGYC
MAB_3183c|M.abscessus_ATCC_199 FGDTQERGRLFATMGTLTPDRIDADAGSFLDFLADQPEVTGELVGLTGYC
: : : * : *.* .: * .* *:*
Rv2054|M.tuberculosis_H37Rv MGGQFALVLS---PRGFGATAPFYGTPLPR-------HLSETLNGACPIV
Mb2080|M.bovis_AF2122/97 MGGQFALVLS---PRGFGATAPFYGTPLPR-------HLSETLNGACPIV
MMAR_3032|M.marinum_M MGGQFALILS---PRGFGASAPFYGTPLPR-------HLSETLDGACPIV
MUL_2272|M.ulcerans_Agy99 MGGQFALILS---PRGFGASAPFYGTPLPR-------HLSETLDGACPIV
MLBr_01444|M.leprae_Br4923 MGGRFALVMS---PKGFDASAPFYGTPLPR-------NLSETLNGACPIV
MAV_2443|M.avium_104 MGGRFALVMS---PKGFGASAPFYGTPLPG-------NLDEVLEGACPVV
MSMEG_2444|M.smegmatis_MC2_155 SGGQFALIMG---PKGFAASAPFYGTPLPR-------HLDRTLDASCPIV
Mflv_4008|M.gilvum_PYR-GCK MGGRTSLVVAGRVPQRVAAAMSFHGGGLVT-DDAESPHLLADRIRAAVYV
Mvan_2379|M.vanbaalenii_PYR-1 MGGRTSLVLAGRLPDRVSAAMSFHGGGLAT-DDPHSPHLLADQMRAAVYV
TH_0693|M.thermoresistible__bu MGGRMSVTVAGRVPDRVAAAASFHAAGLVT-DDPTSPHLLAERIKATVYV
MAB_3183c|M.abscessus_ATCC_199 MGGRISLRVAATHASRVGAVASFHGGNLAKADDLNSPHHLAGRITGVVLI
**: :: :. . . * .*:. * : . :
Rv2054|M.tuberculosis_H37Rv ASFGTRDPLGIGAANRLRKVTAAKNIPADIKSYPGAGHSFANKLPGQPLV
Mb2080|M.bovis_AF2122/97 ASFGTRDPLGIGAANRLRKVTAAKNIPADIKSYPGAGHSFANKLPGQPLV
MMAR_3032|M.marinum_M ASFGNRDPLGLGAPSRLREVTQAKQIPADIKGYPGAGHSFANKLPRQPLL
MUL_2272|M.ulcerans_Agy99 ASFGNRDPLGLGAPSRLREVTQAKQIPADIEGYPGAGHSFANKLPRQPLL
MLBr_01444|M.leprae_Br4923 ASFGGRDPLGIGAPKRLRQATQTRHITTDIKVYPDAGHSFANKLPGQPLM
MAV_2443|M.avium_104 ASFGGRDLTGKGAPEKLRKVTADKNITADIKVYPEAGHSFANELPAQPLL
MSMEG_2444|M.smegmatis_MC2_155 ASFGRRDPLGIGAPARLRRVVEAKNIPADIKVYPSAGHSFANILPAQPLL
Mflv_4008|M.gilvum_PYR-GCK GAAHNDNSFTRADGETLDKALSAAGVEHTVDWYS-AQHGFAVPDNGP---
Mvan_2379|M.vanbaalenii_PYR-1 GAARSDRSFTTEDGERLEKALTSTGVEHTIEWYP-AFHGFAVPDNGP---
TH_0693|M.thermoresistible__bu AGAQDDDGFTPAHAETLGKALTDAGVEHTIEFYP-AGHGFAVPDNLP---
MAB_3183c|M.abscessus_ATCC_199 AAAEEDASFPAEQEQLLGQVLTDAGVRHTIETYP-AKHGFAVTDNPT---
.. * .. : :. *. * *.**
Rv2054|M.tuberculosis_H37Rv RIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGEP
Mb2080|M.bovis_AF2122/97 RIAGFGYNEAATEDAWRRVFEFFGQHLRAGSPGEP
MMAR_3032|M.marinum_M RITGFGYNEAATEDAWGRVFAFFGEHLAAGTSRG-
MUL_2272|M.ulcerans_Agy99 RITGFGYNEAATEDAWGRVFAFFGEHLAAGTSGN-
MLBr_01444|M.leprae_Br4923 RITGFGYNQAATEDAWSRVFAFFDKHLRTD-----
MAV_2443|M.avium_104 RIAGFGYNEEATEDAWRRVFSFFGEHLAATP----
MSMEG_2444|M.smegmatis_MC2_155 RVTGFGYDEAATTDAWTRVFAFFDEHLKPKTAGQA
Mflv_4008|M.gilvum_PYR-GCK ------YDESAARRHWDAMQSFFAAHLV-------
Mvan_2379|M.vanbaalenii_PYR-1 ------YDEPAARRHWEAMRSFFATHLV-------
TH_0693|M.thermoresistible__bu ------YDEQAAERHWDALRALFDRELSG------
MAB_3183c|M.abscessus_ATCC_199 ------YDEGAAQRHWKALEDLYGATLGH------
*:: *: * : :: *