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LIEVAERLFAGRGIEAVTLKEIQQAAGQSNASVIRYHFGSRDGLIRALVSYRQASLAADRQQMLAAMREQ GKEADPRAVVWLLVRPLANSIAAGEMFVPFLARLSEDPRARSDYWPEHVDDEWTQEQLEELVEAALQDFP ERVRRGRTFQLYISLINVLAAAARAGHGLSEAQLHNYVDAWVGMLTAPVSYETRALIAADES*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1916 | - | - | 100% (203) | transcriptional regulator, TetR family protein, putative |
| M. avium 104 | MAV_2626 | - | 5e-99 | 86.63% (202) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_0887 | - | 1e-15 | 29.47% (207) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3081 | - | 5e-05 | 33.77% (77) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2416 | - | 1e-13 | 28.57% (203) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3055 | - | 5e-05 | 33.77% (77) | TetR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0835c | - | 3e-09 | 38.30% (94) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4764 | - | 2e-14 | 30.05% (203) | hypothetical protein MMAR_4764 |
| M. smegmatis MC2 155 | MSMEG_4858 | - | 7e-16 | 29.95% (207) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2278 | - | 2e-11 | 29.06% (203) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0335 | - | 7e-15 | 29.06% (203) | hypothetical protein MUL_0335 |
| M. vanbaalenii PYR-1 | Mvan_4236 | - | 6e-14 | 29.06% (203) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2416|M.gilvum_PYR-GCK MQSGATTFLNGTTHLKQSLDLPGVTRFTDRVTTAR---TVRADRATGTQE
Mvan_4236|M.vanbaalenii_PYR-1 -----MSFLN------QSLDLVGVTGFTEWVTTAR---TVRADRASSTQE
MSMEG_4858|M.smegmatis_MC2_155 ----MTRFTG----------LVTTASRTASRTAAR---TARADRATSTQE
TH_2278|M.thermoresistible__bu -----------------------VVQFTEGVTAAR---TVRADRASSTQE
MMAR_4764|M.marinum_M -----------------------------MTAVGR---AVRGERASSTQE
MUL_0335|M.ulcerans_Agy99 -----------------------------MTAVGR---AVRGERASSTQE
Mb3081|M.bovis_AF2122/97 --------------------MSGAERLGDLPVFARQEPVPERGDAARNRA
Rv3055|M.tuberculosis_H37Rv --------------------MSGAERLGDLPVFARQEPVPERGDAARNRA
MAV_1916|M.avium_104 --------------------------------------------------
MAB_0835c|M.abscessus_ATCC_199 --------------------------MTDTSAETT------ILTEDSTDQ
Mflv_2416|M.gilvum_PYR-GCK AILKAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIE
Mvan_4236|M.vanbaalenii_PYR-1 AILKAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKADLVRAIE
MSMEG_4858|M.smegmatis_MC2_155 AILKAAERLYAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIE
TH_2278|M.thermoresistible__bu AILKAAERLYAERGMFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIE
MMAR_4764|M.marinum_M AILVAAERLFAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIE
MUL_0335|M.ulcerans_Agy99 AILVAAERLFAEHGVFAVSNRQVSEAAGQGNNAAVGYHFGTKTDLVRAIE
Mb3081|M.bovis_AF2122/97 LLLEAARRLIARSGADAITMDDVAAAAGVG-KGTLFRRFGSRAGLMMVLL
Rv3055|M.tuberculosis_H37Rv LLLEAARRLIARSGADAITMDDVAAAAGVG-KGTLFRRFGSRAGLMMVLL
MAV_1916|M.avium_104 MLIEVAERLFAGRGIEAVTLKEIQQAAGQSNASVIRYHFGSRDGLIRALV
MAB_0835c|M.abscessus_ATCC_199 RLLNAAERLFAERGVDAVSLRAIMAAAGTN-VASVHYHFGSKERLIEALL
:: .*.** * * *:: : *** . . : :**:: *: .:
Mflv_2416|M.gilvum_PYR-GCK HKHRGPIEELREQRVAAIDSS---GDMRDWVAALVCPLTDHLAALGNPTW
Mvan_4236|M.vanbaalenii_PYR-1 HKHRGPIEELREQRVAAIGAS---TDMRDWVAALVCPLTDHLAALGNPTW
MSMEG_4858|M.smegmatis_MC2_155 HKHRGPIEYLREQMIGTVQGS---TDLRDWVGALVRPLTDHLAALGNPTW
TH_2278|M.thermoresistible__bu QKHRVEIERLLEKMVAETGDS---TDLRDWVACLVCSLTEHLHQLGNPTW
MMAR_4764|M.marinum_M QKHRVPVERLREQMVAAAAAKGVAATMRDWVACLVCPLTEHLAVLGNPTW
MUL_0335|M.ulcerans_Agy99 QKHRVPIERLREQMVAAAAAKGAAATMRDWVACLVCPLTEHLAVLGNPTW
Mb3081|M.bovis_AF2122/97 DEDERASQQAFLFGPPPLGPD--------------APPLDRLIAFGRERM
Rv3055|M.tuberculosis_H37Rv DEDERASQQAFLFGPPPLGPD--------------APPLDRLIAFGRERM
MAV_1916|M.avium_104 SYRQASLAADRQQMLAAMREQGKEADPRAVVWLLVRPLANSIAAG---EM
MAB_0835c|M.abscessus_ATCC_199 DRYLDQIEKRRFALLDVAETAR---TLRAIAEAIVTPLS-EIAEEGSTAW
. :
Mflv_2416|M.gilvum_PYR-GCK YARFAAQVMTDP-AYHNMIVKDALSSPSLVRVLDGINGCLPDLPVDVRVE
Mvan_4236|M.vanbaalenii_PYR-1 YARFAAQVMTDP-AYHNMIVKDALSSPSLVRVLDGINSCLPDLPVDVRVE
MSMEG_4858|M.smegmatis_MC2_155 YARFAAQVMTDP-AYHNIIVRDALSSPSLVQVIEGMNNCLPDLPAEIRAE
TH_2278|M.thermoresistible__bu YARFAAQALADP-AYQKIVVKDALASPALVRVVEGITRCLPDLPAAVVVE
MMAR_4764|M.marinum_M YARFAAQAMTDP-AYHNIIVKDALSSPSLVQVIDGINSCLPDLPVDVRYE
MUL_0335|M.ulcerans_Agy99 YARFAAQAMTDP-AYHNIIVKDALSSPSLVQVIDGINSCLPDLPVDVRYE
Mb3081|M.bovis_AF2122/97 RFVHAHHQLLSE-ANRDPQTRHSAALSVLRTHLRVLLASAPTT-GDLDAQ
Rv3055|M.tuberculosis_H37Rv RFVHAHHQLLSE-ANRDPQTRHSAALSVLRTHLRVLLASAPTT-GDLDAQ
MAV_1916|M.avium_104 FVPFLARLSEDPRARSDYWPEHVDDEWTQEQLEELVEAALQDFPERVRRG
MAB_0835c|M.abscessus_ATCC_199 LSTLGKLLISGHPALIPMSVSFQPQAARLQELILRLRPDATLPSIRFGVT
. * : .
Mflv_2416|M.gilvum_PYR-GCK RNIMGRNLLMHSCADRERLLAQGSPVPRGSWQSAATGLIDAIIGLWHAPV
Mvan_4236|M.vanbaalenii_PYR-1 RNIMGRNLLMHSCADRERLLAQGAPVARPSWQAAATGLIDAIIGLWHAPV
MSMEG_4858|M.smegmatis_MC2_155 RNIMARNLLMHSCAERERALAQGAPVPRSSWQGAASGLIDAIVGLWLAPV
TH_2278|M.thermoresistible__bu RNIMARNLLMHTCADFERAFAEGDPVPRASWQAVGNGLIDAIVGLWRAPV
MMAR_4764|M.marinum_M RNLMARNLLMHTCADLERALAAGTSVPRPSWREAATGLIDAITGLWLAPV
MUL_0335|M.ulcerans_Agy99 RNLMARNLLMHTCADLERALAAGTSVPRPFWREAATGQIDAITGLWLAPV
Mb3081|M.bovis_AF2122/97 TDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLARKLCGR---------
Rv3055|M.tuberculosis_H37Rv TDALLALLDVDYVEHQLNAGGHTLQTLGDAWESLARKLCGR---------
MAV_1916|M.avium_104 RTFQLYISLINVLAAAARAGHGLSEAQLHNYVDAWVGMLTAPVSYETRAL
MAB_0835c|M.abscessus_ATCC_199 HAVTLTCVVLGDIAHTNRLMSLSGTYLDD--GQMNAQLIDMVTAILAGPP
: .
Mflv_2416|M.gilvum_PYR-GCK TERP--
Mvan_4236|M.vanbaalenii_PYR-1 TEPA--
MSMEG_4858|M.smegmatis_MC2_155 TGEDR-
TH_2278|M.thermoresistible__bu TEPPQ-
MMAR_4764|M.marinum_M TARE--
MUL_0335|M.ulcerans_Agy99 TARE--
Mb3081|M.bovis_AF2122/97 ------
Rv3055|M.tuberculosis_H37Rv ------
MAV_1916|M.avium_104 IAADES
MAB_0835c|M.abscessus_ATCC_199 DES---