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LHNVRRAPKRVRRQSREYRQLIEGAVSQLFDAAVRHPHGDPNSGEYRIEDLARLAGTTTRNIRVYRDRGL LPPPLRVGRIALFNDTHLTRLRLITSMLDRGYTIAHVREMLSAWEQGKNLGDVLGLETAIVGTWTTEKPE TMSLAEAQRLVGDPRAFERLVALQVIRVDGTRATLTRPKLIEAFNEIRGYGVEFDKLIDLHEQIVPEIDK ISDMLVRAGAEHVLDRIKPGEPLPADAEIAELITMLVRFRTQAVATVTATLASSIEANIESLVSRILADY LESSSSA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1794 | - | - | 100% (288) | transcriptional regulator, MerR family protein |
| M. avium 104 | MAV_2720 | - | 4e-05 | 32.47% (77) | transcriptional regulator, MerR family protein |
| M. avium 104 | MAV_1993 | - | 6e-05 | 32.35% (68) | HspR protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3367 | - | 4e-05 | 31.51% (73) | MerR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4902 | - | 1e-100 | 65.70% (277) | MerR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3334 | - | 4e-05 | 31.51% (73) | MerR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4452 | - | 1e-08 | 19.88% (171) | MerR family transcriptional regulator |
| M. marinum M | MMAR_3703 | - | 1e-137 | 82.64% (288) | putative transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_4765 | - | 4e-23 | 42.02% (119) | transcriptional regulator, MerR family protein |
| M. thermoresistible (build 8) | TH_3036 | - | 6e-21 | 31.20% (250) | PUTATIVE putative transcriptional regulator, MerR family |
| M. ulcerans Agy99 | MUL_3645 | - | 1e-105 | 81.70% (224) | putative transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1518 | - | 1e-100 | 66.07% (280) | MerR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3367|M.bovis_AF2122/97 --------------------------------------------------
Rv3334|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_3703|M.marinum_M MIPNGDMTNDRSARPDPGTIASVLHNVRRAPKRVRRQSRELGEFIEAAVT
MUL_3645|M.ulcerans_Agy99 --------------------------------------------------
MAV_1794|M.avium_104 ----------------------MLHNVRRAPKRVRRQSREYRQLIEGAVS
Mflv_4902|M.gilvum_PYR-GCK ----------------------MSGPIQTILRRLRRGSRD---VIENAVS
Mvan_1518|M.vanbaalenii_PYR-1 ----------------------MSGPIQTILRRVRRGSRD---VVENAVS
MSMEG_4765|M.smegmatis_MC2_155 --------------------------------------------------
TH_3036|M.thermoresistible__bu --------------------------------------------------
MAB_4452|M.abscessus_ATCC_1997 --------------------------------------------------
Mb3367|M.bovis_AF2122/97 ------------------MKISEVAALTNTSTKTLRFYENSGLLPPPART
Rv3334|M.tuberculosis_H37Rv ------------------MKISEVAALTNTSTKTLRFYENSGLLPPPART
MMAR_3703|M.marinum_M QLFDAAVRHPNGGAASGEYRIDELARLAGTTTRNIRVYRDRGLLPPPLRV
MUL_3645|M.ulcerans_Agy99 ------------------------------------MYRDRGLLPPPLRV
MAV_1794|M.avium_104 QLFDAAVRHPHGDPNSGEYRIEDLARLAGTTTRNIRVYRDRGLLPPPLRV
Mflv_4902|M.gilvum_PYR-GCK QLFDAAV-QPHDNAESGEYRIEELARLAGTTTRNIRVYRDRGLLHPPLRV
Mvan_1518|M.vanbaalenii_PYR-1 QLFDAAV-QPHGVADSGEYRIDDLARLAGTTTRNIRVYRDRGLLHPPLRV
MSMEG_4765|M.smegmatis_MC2_155 MAAWVSVQGDAGDVGLAEYRLDELAQLSGVNARNIRAYRERGLLDPPRRV
TH_3036|M.thermoresistible__bu ---------------LTEYRLEELAEISGVSPRNIRAYRERGLLGAPRRQ
MAB_4452|M.abscessus_ATCC_1997 ----------------MDLTIDQLAQRVAMTARNIREWQTLGLVPPPEKR
:. **: .* :
Mb3367|M.bovis_AF2122/97 ASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIHDRGEAP------
Rv3334|M.tuberculosis_H37Rv ASGYRNYGPEIVDRLRFIHRGQAAGLALQEVRQILAIHDRGEAP------
MMAR_3703|M.marinum_M GR-IALFNDTHLTRLRLITSMLDRGYNIAHVREMLSAWEEGRNLGDVLGL
MUL_3645|M.ulcerans_Agy99 GR-IALFNDTHLTRLRLITSMLDRGYNIAHVREMLSAWEEGRNLGDVLGL
MAV_1794|M.avium_104 GR-IALFNDTHLTRLRLITSMLDRGYTIAHVREMLSAWEQGKNLGDVLGL
Mflv_4902|M.gilvum_PYR-GCK GR-VALFNDTHVTRLRLITSMLDRGYNLAHVDEMLSAWEQGKDLGDMLGL
Mvan_1518|M.vanbaalenii_PYR-1 GR-IALFNDTHLTRLRLITSLLDRGYNIAHVKEMLSAWEQGKDIGDMLGL
MSMEG_4765|M.smegmatis_MC2_155 GR-SAYYDDAHVAQLRLIASLLNKGFSSAHIAEFFSSVRHGQDLAEALGI
TH_3036|M.thermoresistible__bu GR-SAFYNDAHLAQLRMIDRLLRRGFNSVHIAEFFAAVREGKDLADVLEL
MAB_4452|M.abscessus_ATCC_1997 GR-VGIYSDEHIAIINHVKNLKSQGFPLDVIRRVIDSGSGSEDS--VRKM
. :. : :. : * : ..: ..
Mb3367|M.bovis_AF2122/97 ------------------------------------------------CA
Rv3334|M.tuberculosis_H37Rv ------------------------------------------------CA
MMAR_3703|M.marinum_M ETAIVGSWTTEKPQTMPLAQAQRRVDDPLAFERLVALRLIRIDGT--QAI
MUL_3645|M.ulcerans_Agy99 ETAIVGSWTTEKPQAMPLAQAQRRVDDPLAFERLVALRLIRIDGT--QAI
MAV_1794|M.avium_104 ETAIVGTWTTEKPETMSLAEAQRLVGDPRAFERLVALQVIRVDGT--RAT
Mflv_4902|M.gilvum_PYR-GCK ESAIAGSWAVEKPQRMLTAQARRLIDDPAGFERLVGLGIIRLEDD--HAT
Mvan_1518|M.vanbaalenii_PYR-1 ESAIAGSWATEKPQRMPLTAARRLIDDDAGFDRLVSLGIIRLEDDE-HAT
MSMEG_4765|M.smegmatis_MC2_155 ERAELTAHRSP--------ITADVSESDARTLVEAGLA-ELADG---VFV
TH_3036|M.thermoresistible__bu DRSVLESPRLASQDAAAAILDLDPMGAEAHRLVEYGLARRVQDGRREGIV
MAB_4452|M.abscessus_ATCC_1997 VTEALSPFANGEPVVMPRAELIKRIGAGADSALADTDLVSEVDAAT--VS
Mb3367|M.bovis_AF2122/97 HVRQLLSTRIDEVR---AQIAELIALEGHLQTLLDHAS-----YGPPTEH
Rv3334|M.tuberculosis_H37Rv HVRQLLSTRIDEVR---AQIAELIALEGHLQTLLDHAS-----YGPPTEH
MMAR_3703|M.marinum_M ITRPKLIDAFNEVRGYGISMDKLIDLHEQILPKVDEISDLLVRAGAEHVV
MUL_3645|M.ulcerans_Agy99 IARPKLIDAFNEVRGYGISMDKLIDLHEQILPKVDEISDLLVRAGAEHVV
MAV_1794|M.avium_104 LTRPKLIEAFNEIRGYGVEFDKLIDLHEQIVPEIDKISDMLVRAGAEHVL
Mflv_4902|M.gilvum_PYR-GCK IVRPTLVEAFTEIRRHGVALDKLIDVHEQVAPLLDQIGAILVQAGLDEVL
Mvan_1518|M.vanbaalenii_PYR-1 IVRPTLVEAFAEIRQYGVALDKLIDLHERVTPLLDQISAILVQAGLEEVV
MSMEG_4765|M.smegmatis_MC2_155 LTDPALSAAVAAS----DDQPALIGTAARVARLTADAVDDLAEQAAAVST
TH_3036|M.thermoresistible__bu LTDPVLADVVRHSP---VSHLGYVHVLLRVFEAVREGVDRLAAAAGAAPA
MAB_4452|M.abscessus_ATCC_1997 IRDSETLDAIELLVSSGMTLSRIAETLREVDRLQHQIAQLLLGAYVADVW
. .: .
Mb3367|M.bovis_AF2122/97 DH----------------------------STVCWILESDLDEPTAIEVS
Rv3334|M.tuberculosis_H37Rv DH----------------------------STVCWILESDLDEPTAIEVS
MMAR_3703|M.marinum_M DRIKPGEPLPGDAEIAELITMLIRFRTQAVASITATLASSIESTIESLVS
MUL_3645|M.ulcerans_Agy99 DRIKPGEPLPGDAEIAELITMLIRFRTQAVASITATLASSIESTIESLVS
MAV_1794|M.avium_104 DRIKPGEPLPADAEIAELITMLVRFRTQAVATVTATLASSIEANIESLVS
Mflv_4902|M.gilvum_PYR-GCK DKINPGAAMPDDVEVAELITTLVRFRTHAVSAVGATLAFSIEAQVESVVA
Mvan_1518|M.vanbaalenii_PYR-1 DKINPGAAVPDDVEVAQLITTLVRFRTQAVTAVGATLAFSIESQVESTVA
MSMEG_4765|M.smegmatis_MC2_155 SDPESGQ----AVDITP-------------TVVARAFNHSFHRAFRRALH
TH_3036|M.thermoresistible__bu ATVDAGRNG--GATVAPGASRVERVLADYRRLVGRVVSRYLDEVSARLPV
MAB_4452|M.abscessus_ATCC_1997 QPFVESG--YTSEDWEKIAENASQAKQLTVTLASRLLARALDDTVDPILL
. :.
Mb3367|M.bovis_AF2122/97 DIHA-------------------
Rv3334|M.tuberculosis_H37Rv DIHA-------------------
MMAR_3703|M.marinum_M RLLSDYIEQSSEAQPALRRQQAP
MUL_3645|M.ulcerans_Agy99 PLLSDYIEQSSEAQPALRRQQAP
MAV_1794|M.avium_104 RILADYLESSSSA----------
Mflv_4902|M.gilvum_PYR-GCK ELLGDLISKSAEAAGE-------
Mvan_1518|M.vanbaalenii_PYR-1 QLLGEMIEKTAEAAGE-------
MSMEG_4765|M.smegmatis_MC2_155 LRAS-------------------
TH_3036|M.thermoresistible__bu SRPRP------------------
MAB_4452|M.abscessus_ATCC_1997 QQANEAEAVLERDRPASSA----