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AAWVSVQGDAGDVGLAEYRLDELAQLSGVNARNIRAYRERGLLDPPRRVGRSAYYDDAHVAQLRLIASLL NKGFSSAHIAEFFSSVRHGQDLAEALGIERAELTAHRSPITADVSESDARTLVEAGLAELADGVFVLTDP ALSAAVAASDDQPALIGTAARVARLTADAVDDLAEQAAAVSTSDPESGQAVDITPTVVARAFNHSFHRAF RRALHLRAS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4765 | - | - | 100% (220) | transcriptional regulator, MerR family protein |
| M. smegmatis MC2 155 | MSMEG_3180 | - | 1e-06 | 31.86% (113) | transcriptional regulator, MerR family protein |
| M. smegmatis MC2 155 | MSMEG_1969 | - | 2e-06 | 29.90% (97) | MerR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_2531 | - | 2e-38 | 45.21% (188) | MerR family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4452 | - | 3e-09 | 28.66% (164) | MerR family transcriptional regulator |
| M. marinum M | MMAR_3703 | - | 5e-23 | 48.45% (97) | putative transcriptional regulator |
| M. avium 104 | MAV_1794 | - | 2e-23 | 42.02% (119) | transcriptional regulator, MerR family protein |
| M. thermoresistible (build 8) | TH_3036 | - | 2e-35 | 46.28% (188) | PUTATIVE putative transcriptional regulator, MerR family |
| M. ulcerans Agy99 | MUL_3645 | - | 1e-14 | 49.23% (65) | putative transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4126 | - | 2e-42 | 52.38% (168) | MerR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2531|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_4126|M.vanbaalenii_PYR-1 -------------------------------------------------M
TH_3036|M.thermoresistible__bu --------------------------------------------------
MSMEG_4765|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_3703|M.marinum_M MIPNGDMTNDRSARPDPGTIASVLHNVRRAPKRVRRQSRELGEFIEAAVT
MUL_3645|M.ulcerans_Agy99 --------------------------------------------------
MAV_1794|M.avium_104 ----------------------MLHNVRRAPKRVRRQSREYRQLIEGAVS
MAB_4452|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_2531|M.gilvum_PYR-GCK ---------------MAEYRLEDLARASGVSARNIRAYRERGLLDAPRRV
Mvan_4126|M.vanbaalenii_PYR-1 SAMDWPATCYVWGPGVAEYRLEDLARESGISARNIRAYRERGLLDPPRRV
TH_3036|M.thermoresistible__bu ---------------LTEYRLEELAEISGVSPRNIRAYRERGLLGAPRRQ
MSMEG_4765|M.smegmatis_MC2_155 MAAWVSVQGDAGDVGLAEYRLDELAQLSGVNARNIRAYRERGLLDPPRRV
MMAR_3703|M.marinum_M QLFDAAVRHPNGGAASGEYRIDELARLAGTTTRNIRVYRDRGLLPPPLRV
MUL_3645|M.ulcerans_Agy99 ------------------------------------MYRDRGLLPPPLRV
MAV_1794|M.avium_104 QLFDAAVRHPHGDPNSGEYRIEDLARLAGTTTRNIRVYRDRGLLPPPLRV
MAB_4452|M.abscessus_ATCC_1997 ----------------MDLTIDQLAQRVAMTARNIREWQTLGLVPPPEKR
:: **: .* :
Mflv_2531|M.gilvum_PYR-GCK GRAALYDDYHLSQLNTISELLRKGYNSAHIAEFFESIRQGADLADILGLQ
Mvan_4126|M.vanbaalenii_PYR-1 GRSALYDDYHLSQLNTISQLLRKGYNSAHIAEFFASMRQGTDLADILGLQ
TH_3036|M.thermoresistible__bu GRSAFYNDAHLAQLRMIDRLLRRGFNSVHIAEFFAAVREGKDLADVLELD
MSMEG_4765|M.smegmatis_MC2_155 GRSAYYDDAHVAQLRLIASLLNKGFSSAHIAEFFSSVRHGQDLAEALGIE
MMAR_3703|M.marinum_M GRIALFNDTHLTRLRLITSMLDRGYNIAHVREMLSAWEEGRNLGDVLGLE
MUL_3645|M.ulcerans_Agy99 GRIALFNDTHLTRLRLITSMLDRGYNIAHVREMLSAWEEGRNLGDVLGLE
MAV_1794|M.avium_104 GRIALFNDTHLTRLRLITSMLDRGYTIAHVREMLSAWEQGKNLGDVLGLE
MAB_4452|M.abscessus_ATCC_1997 GRVGIYSDEHIAIINHVKNLKSQGFPLDVIRRVIDSGSGSEDS--VRKMV
** . :.* *:: :. : : :*: : ..: : . : :
Mflv_2531|M.gilvum_PYR-GCK RAVLG-RDAEESERHGGPVHIDPHGEEGRELVRYGMA-EVVDGR---LMM
Mvan_4126|M.vanbaalenii_PYR-1 RAVLG-QTPEPRNRN-TAVKIDAKSEEARKLVAFGMA-EVVDGE---VLM
TH_3036|M.thermoresistible__bu RSVLESPRLASQDAAAAILDLDPMGAEAHRLVEYGLARRVQDGRREGIVL
MSMEG_4765|M.smegmatis_MC2_155 RAELT--------AHRSPITADVSESDARTLVEAGLA-ELADGV---FVL
MMAR_3703|M.marinum_M TAIVG--SWTTEKPQTMPLAQAQRRVDDPLAFERLVALRLIRIDGTQAII
MUL_3645|M.ulcerans_Agy99 TAIVG--SWTTEKPQAMPLAQAQRRVDDPLAFERLVALRLIRIDGTQAII
MAV_1794|M.avium_104 TAIVG--TWTTEKPETMSLAEAQRLVGDPRAFERLVALQVIRVDGTRATL
MAB_4452|M.abscessus_ATCC_1997 TEALS--PFANGEPVVMPRAELIKRIGAGADSALADTDLVSEVDAATVSI
: : : :
Mflv_2531|M.gilvum_PYR-GCK VDDTAAEILDRAPDPAL-YIRALVRFVEGAQESVDALAEAFVTNLTEVYH
Mvan_4126|M.vanbaalenii_PYR-1 IDCAAADILARSPDQLL-YVRALLRFVEAAEDSVDDLAEAFVTSLGELYH
TH_3036|M.thermoresistible__bu TDPVLADVVRHSPVSHLGYVHVLLRVFEAVREGVDRLAAAAGAAPAATVD
MSMEG_4765|M.smegmatis_MC2_155 TDPALSAAVAASDDQPA-LIGTAARVARLTADAVDDLAEQAAAVSTSDPE
MMAR_3703|M.marinum_M TRPKLIDAFNEVRGYGI-SMDKLIDLHEQILPKVDEISDLLVRAGAEHVV
MUL_3645|M.ulcerans_Agy99 ARPKLIDAFNEVRGYGI-SMDKLIDLHEQILPKVDEISDLLVRAGAEHVV
MAV_1794|M.avium_104 TRPKLIEAFNEIRGYGV-EFDKLIDLHEQIVPEIDKISDMLVRAGAEHVL
MAB_4452|M.abscessus_ATCC_1997 RDSETLDAIELLVSSGM-TLSRIAETLREVDRLQHQIAQLLLGAYVADVW
. . . . ::
Mflv_2531|M.gilvum_PYR-GCK ARVG-VDRLPRPED--SDVLRQVIEDYRALGDRVMAVQFAKATRRHMVAS
Mvan_4126|M.vanbaalenii_PYR-1 ARVG-ADYLPRPDE--VDEIRQVVQDYRALGEKVMVARFDQATRRRMVAS
TH_3036|M.thermoresistible__bu AGRN-GGATVAPG---ASRVERVLADYRRLVGRVVSRYLDEVSARLPVS-
MSMEG_4765|M.smegmatis_MC2_155 SG-------------------QAVDITPTVVARAFNHSFHRAFRRALHLR
MMAR_3703|M.marinum_M DRIKPGEPLPGDAE--IAELITMLIRFRTQAVASITATLASSIESTIESL
MUL_3645|M.ulcerans_Agy99 DRIKPGEPLPGDAE--IAELITMLIRFRTQAVASITATLASSIESTIESL
MAV_1794|M.avium_104 DRIKPGEPLPADAE--IAELITMLVRFRTQAVATVTATLASSIEANIESL
MAB_4452|M.abscessus_ATCC_1997 QPFVESGYTSEDWEKIAENASQAKQLTVTLASRLLARALDDTVDPILLQQ
. :
Mflv_2531|M.gilvum_PYR-GCK ASGYTAGILLDGAWQPRRGA-----
Mvan_4126|M.vanbaalenii_PYR-1 ASGYTAGILLSGAWEPKRGA-----
TH_3036|M.thermoresistible__bu --------------RPRP-------
MSMEG_4765|M.smegmatis_MC2_155 AS-----------------------
MMAR_3703|M.marinum_M VSRLLSDYIEQSSEAQPALRRQQAP
MUL_3645|M.ulcerans_Agy99 VSPLLSDYIEQSSEAQPALRRQQAP
MAV_1794|M.avium_104 VSRILADYLESSSSA----------
MAB_4452|M.abscessus_ATCC_1997 ANEAEAVLERDRPASSA--------