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LTGDATARSARGVYGISVAAELSATPPQTLRLYERRGLLTPSRTDGGTRRYSDDDLERLKRISELVGQGI NLAGIARILHLETENNQLKSDYTRLQLSNAKLRDRSKPSPSRATSRRTGEKQTP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1993 | - | - | 100% (124) | HspR protein |
| M. avium 104 | MAV_2720 | - | 2e-41 | 67.50% (120) | transcriptional regulator, MerR family protein |
| M. avium 104 | MAV_4105 | - | 1e-28 | 58.88% (107) | transcriptional regulator, MerR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0361 | hspR | 6e-15 | 47.19% (89) | HEAT shock protein transcriptional regulator HspR |
| M. gilvum PYR-GCK | Mflv_0257 | - | 4e-15 | 45.36% (97) | MerR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0353 | hspR | 7e-15 | 47.19% (89) | HEAT shock protein transcriptional repressor HspR |
| M. leprae Br4923 | MLBr_02493 | hspR | 7e-15 | 48.78% (82) | heat shock regulator |
| M. abscessus ATCC 19977 | MAB_3468 | - | 4e-24 | 63.75% (80) | MerR family transcriptional regulator |
| M. marinum M | MMAR_2990 | hspR_2 | 2e-26 | 55.05% (109) | heat shock protein transcriptional repressor HspR_2 |
| M. smegmatis MC2 155 | MSMEG_0713 | - | 1e-15 | 46.32% (95) | transcriptional regulator, MerR family protein |
| M. thermoresistible (build 8) | TH_2359 | hspR | 1e-14 | 41.38% (116) | PROBABLE HEAT SHOCK PROTEIN TRANSCRIPTIONAL REPRESSOR HSPR |
| M. ulcerans Agy99 | MUL_0596 | hspR | 3e-15 | 50.00% (82) | heat shock protein transcriptional repressor HspR |
| M. vanbaalenii PYR-1 | Mvan_0637 | - | 5e-15 | 45.36% (97) | MerR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0257|M.gilvum_PYR-GCK -MSG----------------------RKEEARTFLISVAAELAGMHAQTL
Mvan_0637|M.vanbaalenii_PYR-1 -MSAGRPS------------------RKEDARTFLISVAAELAGMHAQTL
MSMEG_0713|M.smegmatis_MC2_155 -MSG---K------------------RNEEARTFLISVAAELAGMHAQTL
TH_2359|M.thermoresistible__bu -VSRSK-R------------------SNDDTRTFMISVAAELAGMHAQTL
Mb0361|M.bovis_AF2122/97 -MAKNPKD--------------------GESRTFLISVAAELAGMHAQTL
Rv0353|M.tuberculosis_H37Rv -MAKNPKD--------------------GESRTFLISVAAELAGMHAQTL
MUL_0596|M.ulcerans_Agy99 -MAKNSRE--------------------GEARTFLISVAAELAGMHAQTL
MLBr_02493|M.leprae_Br4923 MMTRNSRDP-----------------RQQESRTFLISAAAELAGMHAQTL
MAB_3468|M.abscessus_ATCC_1997 -MVPEDVLYPSGSPVPRLEGPRPPELPAPEKGVYGISVAAELSGAATQSL
MMAR_2990|M.marinum_M -MADR----------PGHAGG-----PAPDVGVYGISVTAELSGIAVQSL
MAV_1993|M.avium_104 -MTGD-----------ATARS--------ARGVYGISVAAELSATPPQTL
: .: **.:***:. *:*
Mflv_0257|M.gilvum_PYR-GCK RTYDRLGLVSPQRSSGGGRRYSQRDVDLLREVQRLSQDEGVNLAGIKRII
Mvan_0637|M.vanbaalenii_PYR-1 RTYDRLGLVSPQRSSGGGRRYSQRDVDLLREVQRLSQDEGVNLAGIKRII
MSMEG_0713|M.smegmatis_MC2_155 RTYDRLGLVTPQRTSGGGRRYSERDVDLLREVQRLSQDEGVNLAGIKRII
TH_2359|M.thermoresistible__bu RTYDRLGLVRPKRSPGGGRRYSWRDVELLREVQRLSQDEGVNLAGIKRII
Mb0361|M.bovis_AF2122/97 RTYDRLGLVSPRRTSGGGRRYSLHDVELLRQVQHLSQDEGVNLAGIKRII
Rv0353|M.tuberculosis_H37Rv RTYDRLGLVSPRRTSGGGRRYSLHDVELLRQVQHLSQDEGVNLAGIKRII
MUL_0596|M.ulcerans_Agy99 RTYDRLGLVSPRRTSGGGRRYSEHDVNLLRQVQQLSQEEGVNLAGIKRII
MLBr_02493|M.leprae_Br4923 RTYDRLGLVSPSRASGGGRRYSQHDVELLRQVQRLSQNEGVNLAGIKRII
MAB_3468|M.abscessus_ATCC_1997 RLWERHGLLAPSRTEGGTRRYSPEDLIRIRRITTLVA-AGVNIAGIAFIL
MMAR_2990|M.marinum_M RLYERHGLVTPARSEGGTRRYSADDLVRLQRVSVLIE-AGINLAGISRIL
MAV_1993|M.avium_104 RLYERRGLLTPSRTDGGTRRYSDDDLERLKRISELVG-QGINLAGIARIL
* ::* **: * *: ** **** *: ::.: * *:*:*** *:
Mflv_0257|M.gilvum_PYR-GCK ELTNQVEALQSRVRELTNEVEHLRSQPR------PKSTALVVWQ------
Mvan_0637|M.vanbaalenii_PYR-1 ELTNQVEALQARVRELSDEVERLRAQPR------PKSTALVVWQ------
MSMEG_0713|M.smegmatis_MC2_155 ELTNQVDALQRRVAELTAEVERLR---K------P-STALVLWQ------
TH_2359|M.thermoresistible__bu ELTNQVEQLQARVKELTQELEQMRSVPRRELAVVPKSTAVVLWK------
Mb0361|M.bovis_AF2122/97 ELTSQVEALQSRLQEMAEELAVLRANQRREVAVVPKSTALVVWK------
Rv0353|M.tuberculosis_H37Rv ELTSQVEALQSRLQEMAEELAVLRANQRREVAVVPKSTALVVWK------
MUL_0596|M.ulcerans_Agy99 ELTNQVEALQSRLQEMADELETMRAKQRREVALVPRSTALVVWQRAGPAE
MLBr_02493|M.leprae_Br4923 ELTNQVEALQLKLQELTDELVMLRANQRRDLAVVPKSTALVLWQ------
MAB_3468|M.abscessus_ATCC_1997 ELEDDNTALRAAVYD---QQRRHSDTDR----------------------
MMAR_2990|M.marinum_M NLEDDNAALAAANCDLLASNRSLRDAARAAVRLMNHGRSAENGE------
MAV_1993|M.avium_104 HLETENNQLKSDYTRLQLSNAKLRDRSKPSPSRATSRRTGEKQT------
.* : * . :
Mflv_0257|M.gilvum_PYR-GCK ------------------PRHQR--------
Mvan_0637|M.vanbaalenii_PYR-1 ------------------PRNQR--------
MSMEG_0713|M.smegmatis_MC2_155 ------------------PRNNRKR------
TH_2359|M.thermoresistible__bu ------------------PRRSGEKT-----
Mb0361|M.bovis_AF2122/97 ------------------PRR----------
Rv0353|M.tuberculosis_H37Rv ------------------PRR----------
MUL_0596|M.ulcerans_Agy99 PAFRHTPPGYGPVPVLKNPERLDPVLKKPEM
MLBr_02493|M.leprae_Br4923 ------------------PRKPR--------
MAB_3468|M.abscessus_ATCC_1997 -------------------------------
MMAR_2990|M.marinum_M ------------------GGDTS--------
MAV_1993|M.avium_104 ------------------P------------