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SGPIQTILRRVRRGSRDVVENAVSQLFDAAVQPHGVADSGEYRIDDLARLAGTTTRNIRVYRDRGLLHPP LRVGRIALFNDTHLTRLRLITSLLDRGYNIAHVKEMLSAWEQGKDIGDMLGLESAIAGSWATEKPQRMPL TAARRLIDDDAGFDRLVSLGIIRLEDDEHATIVRPTLVEAFAEIRQYGVALDKLIDLHERVTPLLDQISA ILVQAGLEEVVDKINPGAAVPDDVEVAQLITTLVRFRTQAVTAVGATLAFSIESQVESTVAQLLGEMIEK TAEAAGE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1518 | - | - | 100% (288) | MerR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4126 | - | 1e-24 | 42.97% (128) | MerR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4902 | - | 1e-137 | 85.42% (288) | MerR family transcriptional regulator |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4452 | - | 2e-09 | 21.37% (234) | MerR family transcriptional regulator |
| M. marinum M | MMAR_3703 | - | 1e-102 | 66.43% (280) | putative transcriptional regulator |
| M. avium 104 | MAV_1794 | - | 1e-100 | 66.07% (280) | transcriptional regulator, MerR family protein |
| M. smegmatis MC2 155 | MSMEG_4765 | - | 3e-23 | 38.60% (171) | transcriptional regulator, MerR family protein |
| M. thermoresistible (build 8) | TH_3036 | - | 2e-23 | 35.35% (198) | PUTATIVE putative transcriptional regulator, MerR family |
| M. ulcerans Agy99 | MUL_3645 | - | 1e-82 | 65.33% (225) | putative transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1518|M.vanbaalenii_PYR-1 ----------------------MSGPIQTILRRVRRGSR---DVVENAVS
Mflv_4902|M.gilvum_PYR-GCK ----------------------MSGPIQTILRRLRRGSR---DVIENAVS
MMAR_3703|M.marinum_M MIPNGDMTNDRSARPDPGTIASVLHNVRRAPKRVRRQSRELGEFIEAAVT
MUL_3645|M.ulcerans_Agy99 --------------------------------------------------
MAV_1794|M.avium_104 ----------------------MLHNVRRAPKRVRRQSREYRQLIEGAVS
MSMEG_4765|M.smegmatis_MC2_155 --------------------------------------------------
TH_3036|M.thermoresistible__bu --------------------------------------------------
MAB_4452|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_1518|M.vanbaalenii_PYR-1 QLFDAAV-QPHGVADSGEYRIDDLARLAGTTTRNIRVYRDRGLLHPPLRV
Mflv_4902|M.gilvum_PYR-GCK QLFDAAV-QPHDNAESGEYRIEELARLAGTTTRNIRVYRDRGLLHPPLRV
MMAR_3703|M.marinum_M QLFDAAVRHPNGGAASGEYRIDELARLAGTTTRNIRVYRDRGLLPPPLRV
MUL_3645|M.ulcerans_Agy99 ------------------------------------MYRDRGLLPPPLRV
MAV_1794|M.avium_104 QLFDAAVRHPHGDPNSGEYRIEDLARLAGTTTRNIRVYRDRGLLPPPLRV
MSMEG_4765|M.smegmatis_MC2_155 MAAWVSVQGDAGDVGLAEYRLDELAQLSGVNARNIRAYRERGLLDPPRRV
TH_3036|M.thermoresistible__bu ---------------LTEYRLEELAEISGVSPRNIRAYRERGLLGAPRRQ
MAB_4452|M.abscessus_ATCC_1997 ----------------MDLTIDQLAQRVAMTARNIREWQTLGLVPPPEKR
:: **: .* :
Mvan_1518|M.vanbaalenii_PYR-1 GRIALFNDTHLTRLRLITSLLDRGYNIAHVKEMLSAWEQGKDIGDMLGLE
Mflv_4902|M.gilvum_PYR-GCK GRVALFNDTHVTRLRLITSMLDRGYNLAHVDEMLSAWEQGKDLGDMLGLE
MMAR_3703|M.marinum_M GRIALFNDTHLTRLRLITSMLDRGYNIAHVREMLSAWEEGRNLGDVLGLE
MUL_3645|M.ulcerans_Agy99 GRIALFNDTHLTRLRLITSMLDRGYNIAHVREMLSAWEEGRNLGDVLGLE
MAV_1794|M.avium_104 GRIALFNDTHLTRLRLITSMLDRGYTIAHVREMLSAWEQGKNLGDVLGLE
MSMEG_4765|M.smegmatis_MC2_155 GRSAYYDDAHVAQLRLIASLLNKGFSSAHIAEFFSSVRHGQDLAEALGIE
TH_3036|M.thermoresistible__bu GRSAFYNDAHLAQLRMIDRLLRRGFNSVHIAEFFAAVREGKDLADVLELD
MAB_4452|M.abscessus_ATCC_1997 GRVGIYSDEHIAIINHVKNLKSQGFPLDVIRRVIDSGSGSEDS--VRKMV
** . :.* *:: :. : : :*: : ..: : ..: :
Mvan_1518|M.vanbaalenii_PYR-1 SAIAGSWATEKPQRMPLTAARRLIDDDAGFDRLVSLGIIRLEDDE-HATI
Mflv_4902|M.gilvum_PYR-GCK SAIAGSWAVEKPQRMLTAQARRLIDDPAGFERLVGLGIIRLEDD--HATI
MMAR_3703|M.marinum_M TAIVGSWTTEKPQTMPLAQAQRRVDDPLAFERLVALRLIRIDGT--QAII
MUL_3645|M.ulcerans_Agy99 TAIVGSWTTEKPQAMPLAQAQRRVDDPLAFERLVALRLIRIDGT--QAII
MAV_1794|M.avium_104 TAIVGTWTTEKPETMSLAEAQRLVGDPRAFERLVALQVIRVDGT--RATL
MSMEG_4765|M.smegmatis_MC2_155 RAELTAHRSP--------ITADVSESDARTLVEAGLA-ELADG---VFVL
TH_3036|M.thermoresistible__bu RSVLESPRLASQDAAAAILDLDPMGAEAHRLVEYGLARRVQDGRREGIVL
MAB_4452|M.abscessus_ATCC_1997 TEALSPFANGEPVVMPRAELIKRIGAGADSALADTDLVSEVDAA--TVSI
. : :
Mvan_1518|M.vanbaalenii_PYR-1 VRPTLVEAFAEIRQYGVALDKLIDLHERVTPLLDQISAILVQAGLEEVVD
Mflv_4902|M.gilvum_PYR-GCK VRPTLVEAFTEIRRHGVALDKLIDVHEQVAPLLDQIGAILVQAGLDEVLD
MMAR_3703|M.marinum_M TRPKLIDAFNEVRGYGISMDKLIDLHEQILPKVDEISDLLVRAGAEHVVD
MUL_3645|M.ulcerans_Agy99 ARPKLIDAFNEVRGYGISMDKLIDLHEQILPKVDEISDLLVRAGAEHVVD
MAV_1794|M.avium_104 TRPKLIEAFNEIRGYGVEFDKLIDLHEQIVPEIDKISDMLVRAGAEHVLD
MSMEG_4765|M.smegmatis_MC2_155 TDPALSAAVAAS----DDQPALIGTAARVARLTADAVDDLAEQAAAVSTS
TH_3036|M.thermoresistible__bu TDPVLADVVRHSP---VSHLGYVHVLLRVFEAVREGVDRLAAAAGAAPAA
MAB_4452|M.abscessus_ATCC_1997 RDSETLDAIELLVSSGMTLSRIAETLREVDRLQHQIAQLLLGAYVADVWQ
. .. .: . *
Mvan_1518|M.vanbaalenii_PYR-1 -KINPGAAVPDDVEVAQLITTLVRFRTQAVTAVGATLAFSIESQVESTVA
Mflv_4902|M.gilvum_PYR-GCK -KINPGAAMPDDVEVAELITTLVRFRTHAVSAVGATLAFSIEAQVESVVA
MMAR_3703|M.marinum_M -RIKPGEPLPGDAEIAELITMLIRFRTQAVASITATLASSIESTIESLVS
MUL_3645|M.ulcerans_Agy99 -RIKPGEPLPGDAEIAELITMLIRFRTQAVASITATLASSIESTIESLVS
MAV_1794|M.avium_104 -RIKPGEPLPADAEIAELITMLVRFRTQAVATVTATLASSIEANIESLVS
MSMEG_4765|M.smegmatis_MC2_155 -DPESGQ----AVDITP-------------TVVARAFNHSFHRAFRRALH
TH_3036|M.thermoresistible__bu -TVDAGRNG--GATVAPGASRVERVLADYRRLVGRVVSRYLDEVSARLPV
MAB_4452|M.abscessus_ATCC_1997 PFVESGYTSEDWEKIAENASQAKQLT---VTLASRLLARALDDTVDPILL
..* :: . :.
Mvan_1518|M.vanbaalenii_PYR-1 QLLGEMIEKTAEAAGE-------
Mflv_4902|M.gilvum_PYR-GCK ELLGDLISKSAEAAGE-------
MMAR_3703|M.marinum_M RLLSDYIEQSSEAQPALRRQQAP
MUL_3645|M.ulcerans_Agy99 PLLSDYIEQSSEAQPALRRQQAP
MAV_1794|M.avium_104 RILADYLESSSSA----------
MSMEG_4765|M.smegmatis_MC2_155 LRAS-------------------
TH_3036|M.thermoresistible__bu SRPRP------------------
MAB_4452|M.abscessus_ATCC_1997 QQANEAEAVLERDRPASSA----