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MTQTNLARPQGLTRIDPVLRDTAAQLGVVEFRAETLAAEREHANRLAAQRAASADTRGVAIDSVSIAGPD GQPLELRLYRGHTESAAPLLVYAHGGAFVTGNLATDHAHCVELARDGGCLVVSVDYRLAPENPCPAALDD VEAAFRYVVDNSAALNADANRIAVMGRDAGAALVAGLTQRMFDQEGPTILMQILHQPMLDSDATPSRREF QRTPGLNGPAVSRAWNHYLGHASASGQHVPAHRANLEGLPPTFISCSEIDPCRDEAIDYANRLLHAYVHT ELHVIAATFNGFDSMVPDWIVAQENRALHAQALRRVFAM
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1617 | - | - | 100% (319) | alpha/beta hydrolase domain-containing protein |
| M. avium 104 | MAV_5118 | - | 1e-67 | 47.19% (303) | alpha/beta hydrolase domain-containing protein |
| M. avium 104 | MAV_3377 | - | 9e-36 | 35.86% (304) | alpha/beta hydrolase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1435c | lipI | 4e-34 | 34.72% (288) | lipase LipH |
| M. gilvum PYR-GCK | Mflv_4102 | - | 5e-73 | 46.71% (304) | alpha/beta hydrolase domain-containing protein |
| M. tuberculosis H37Rv | Rv1400c | lipI | 4e-34 | 34.72% (288) | lipase LipH |
| M. leprae Br4923 | MLBr_00314 | - | 8e-08 | 27.07% (229) | putative esterase |
| M. abscessus ATCC 19977 | MAB_3270c | - | 1e-32 | 35.62% (292) | lipase/esterase LipN |
| M. marinum M | MMAR_0404 | lipW | 2e-72 | 45.05% (313) | esterase LipW |
| M. smegmatis MC2 155 | MSMEG_2568 | - | 4e-70 | 47.27% (311) | LipW protein |
| M. thermoresistible (build 8) | TH_2562 | - | 5e-73 | 47.25% (309) | PUTATIVE Alpha/beta hydrolase fold-3 domain protein |
| M. ulcerans Agy99 | MUL_1054 | lipW | 9e-66 | 47.23% (271) | esterase LipW |
| M. vanbaalenii PYR-1 | Mvan_2244 | - | 1e-71 | 47.04% (304) | alpha/beta hydrolase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1435c|M.bovis_AF2122/97 --------------------MPSLDNTADEKPAIDPILLKVLDAVPFR--
Rv1400c|M.tuberculosis_H37Rv --------------------MPSLDNTADEKPAIDPILLKVLDAVPFR--
MAB_3270c|M.abscessus_ATCC_199 MSPFRDFALRASTAATPHIPTPVRRAMAGRQVIIDGNILDPTTQLLLRGM
Mflv_4102|M.gilvum_PYR-GCK -----------------------MT--RDIAERLDPQLRHLAAAR--TDL
Mvan_2244|M.vanbaalenii_PYR-1 -----------------------MTD-RDITERLDPALRHLAGAR--TDL
MSMEG_2568|M.smegmatis_MC2_155 -----------------------MAHRSGWTERLDPALREFAGAR--TDL
TH_2562|M.thermoresistible__bu ------------------------VNPPEAGQRLAPELRHLWGTR--TDL
MMAR_0404|M.marinum_M ------------------------MTQPEAVDRLDPLLRAVATAR--IDF
MUL_1054|M.ulcerans_Agy99 --------------------------------------------------
MAV_1617|M.avium_104 -------------------MTQTNLARPQGLTRIDPVLRDTAAQLGVVEF
MLBr_00314|M.leprae_Br4923 ----------------MAISAGAPVEIVESGPSIAARLASLTSRLTIRPI
Mb1435c|M.bovis_AF2122/97 -------LSIDDGIEAVRQRLRDLP--RQPVHPELRVVDLAIDGPAGPIG
Rv1400c|M.tuberculosis_H37Rv -------LSIDDGIEAVRQRLRDLP--RQPVHPELRVVDLAIDGPAGPIG
MAB_3270c|M.abscessus_ATCC_199 ELMGEGEISRGEDVAENRANMRRQAGLLQFSTPVGQVRNFSIPGPAGPIG
Mflv_4102|M.gilvum_PYR-GCK SP-----PVLGAVRDSLNQRRAETARTADLIG-VEVEQREVPVPAGHTVT
Mvan_2244|M.vanbaalenii_PYR-1 SP-----PVLGAVRDSLNQRRAETARSVDTVG-VEIEQREVPVPAGHRVT
MSMEG_2568|M.smegmatis_MC2_155 SP-----ETLAVVRASIDRRRRESAQTLDTFG-VAIAGGRAALGR-RSVP
TH_2562|M.thermoresistible__bu TA-----DLLPTVRAVLDDRRRATAAAVDTGG-VHIDDREIHCGT-GPIE
MMAR_0404|M.marinum_M TA-----ESILTIRESMNQRRREAAATETAAAGVAVADDVVTGEAGRPVP
MUL_1054|M.ulcerans_Agy99 ----------------MNQRRREAAATETAAAGVAVADDVATGEAGRPVP
MAV_1617|M.avium_104 RA-----ETLAAEREHANRLAAQRAASADTRG-VAIDSVSIAGPDGQPLE
MLBr_00314|M.leprae_Br4923 LAVG----SYVPQLPWPFGLIDHAARVLLPVTNAARAEVNLSNTSAQLVR
. :
Mb1435c|M.bovis_AF2122/97 TRIYWPPTCPD-QAEAPVVLYFHGGGFVMGDLDTHDGTCRQHAVGADAIV
Rv1400c|M.tuberculosis_H37Rv TRIYWPPTCPD-QAEAPVVLYFHGGGFVMGDLDTHDGTCRQHAVGADAIV
MAB_3270c|M.abscessus_ATCC_199 VRHYKP--VHD-HTGA-LLVFFHGGGWVIGDLETHDQPCRQTCRDAGVSV
Mflv_4102|M.gilvum_PYR-GCK VRIYRGG-----PPQSPAVIYCHSGAFVLGNLDTDHRQCIEMARRGRCTV
Mvan_2244|M.vanbaalenii_PYR-1 VRIYRGG-----PPGSGVVLYCHSGAFVLGTLDTDHRQCIEMARRGRCTV
MSMEG_2568|M.smegmatis_MC2_155 VRIYRGG-----PSPAPVVVYCHSGAFVLGNLDVDQRQCVELARRGQCTV
TH_2562|M.thermoresistible__bu IRIYRGR-----RGVAPAVLYCHAGAFVLGNLDTDHRQCVELARRAECTV
MMAR_0404|M.marinum_M VRIYRAA-----PTPAPVVVYCHAGGFALGNLDTDHRQCLELARRARCAV
MUL_1054|M.ulcerans_Agy99 VRIYRAA-----PTPAPVVVYCHAGGFALGNLDTDHRQCLERARRARCAV
MAV_1617|M.avium_104 LRLYRGH----TESAAPLLVYAHGGAFVTGNLATDHAHCVELARDGGCLV
MLBr_00314|M.leprae_Br4923 AAGVRPA-----DGSGRIVLYLHGGAFLGCGANSHRRLVETLSKLADSPI
. ::: *.*.: . . . :
Mb1435c|M.bovis_AF2122/97 VSVDYRLAPEHPYPAAIEDAWAATRWVAEHGRQVGADLGRIAVAGDSAGG
Rv1400c|M.tuberculosis_H37Rv VSVDYRLAPEHPYPAAIEDAWAATRWVAEHGRQVGADLGRIAVAGDSAGG
MAB_3270c|M.abscessus_ATCC_199 LSVDYRLAPEHKAPAAAQDCLAAYLWAVEHAGDLGVAPDRIAVGGDSAGG
Mflv_4102|M.gilvum_PYR-GCK LSVDYRLAPEHPYPAAQDDVSAILDWAVRCSAELGIDATAVAVAGSSAGA
Mvan_2244|M.vanbaalenii_PYR-1 LSVDYRLAPEHPYPAALDDAAAILDWGVGNAAELGIDAAAVALAGSSAGA
MSMEG_2568|M.smegmatis_MC2_155 VAMDYRLAPEHPYPAALDDAAMVLAWVAAQAGELDVDPDRIAVAGSSAGG
TH_2562|M.thermoresistible__bu VSVDYRLAPEHPWPAAVDDATAVLSWLAGNATALDVDPARLAVAGSSAGG
MMAR_0404|M.marinum_M VSVDYRLAPEHPYPAALHDAIEVLTWVVGNATRLGFDARRLAVAGSSAGA
MUL_1054|M.ulcerans_Agy99 VSVDYRLAPEHPYPAALRDAIEVLTWVVGNATRLGFDARRLAVAGSSAGA
MAV_1617|M.avium_104 VSVDYRLAPENPCPAALDDVEAAFRYVVDNSAALNADANRIAVMGRDAGA
MLBr_00314|M.leprae_Br4923 LVVNYRLLPKHSIGMALDDCHDGYQWLRR----LGYDPEQIVLAGDSAGG
: ::*** *:: * * : :. :.: * .**.
Mb1435c|M.bovis_AF2122/97 TIAAVIAQRARDMGGPPIVFQLLWYPSTLWDQSLPSLAENADAPILDVKA
Rv1400c|M.tuberculosis_H37Rv TIAAVIAQRARDMGGPPIVFQLLWYPSTLWDQSLPSLAENADAPILDVKA
MAB_3270c|M.abscessus_ATCC_199 NLAAVVAQQARDTGAQLPLLQFLIYPAVDFTVRRPSRDLFAEGFFLTKAA
Mflv_4102|M.gilvum_PYR-GCK ALAAGLARRSAAGDGPPVVFQMLHQPVLDDRPS-PSKDEFTTTPGFDAEA
Mvan_2244|M.vanbaalenii_PYR-1 SLVAGLAQRSAAGGAPPVVFQLLHQPVLDDRPS-PSKEEFTNTPGFDSQA
MSMEG_2568|M.smegmatis_MC2_155 ALAALLAQRSATGAAPPIVFQLLHQPVLDDRPT-RSKREFVDTPGFDGPA
TH_2562|M.thermoresistible__bu ALAAGLAQRSGRNGLPQLVFQLLHQPALDDRVT-PSKAEFCTTPGFDGPA
MMAR_0404|M.marinum_M TLAAGLAHGAADGSLPPVIFQLLHQPVLDDRPT-ASRSEFRATPAFDGEA
MUL_1054|M.ulcerans_Agy99 TLAAGLAHGAADGSLPPVIFQLLHQPVLDDRPT-ASRSEFRATPAFDGEA
MAV_1617|M.avium_104 ALVAGLTQRMFDQEGPTILMQILHQPMLDSDAT-PSRREFQRTPGLNGPA
MLBr_00314|M.leprae_Br4923 YLALALAQRLQDVGEEPAALVAISPLLQLAKKGKQAHPNAKTDAMFPPKA
:. ::: : : : : *
Mb1435c|M.bovis_AF2122/97 IAAFSRWYAGEIDL---HNPPAPMAPGRAENLADLPPAYIAVAGYDPLRD
Rv1400c|M.tuberculosis_H37Rv IAAFSRWYAGEIDL---HNPPAPMAPGRAENLADLPPAYIAVAGYDPLRD
MAB_3270c|M.abscessus_ATCC_199 MDGFESHYLDGSDV---DKADPQVSPILAADLAGLPPALITTAGFDPLRD
Mflv_4102|M.gilvum_PYR-GCK VAWMWRHYGGD------ASLPDEAVPARIEEMSSLPAALITCSELDPLRD
Mvan_2244|M.vanbaalenii_PYR-1 VQWMWRHYGGG------DPLPEDAVPARADELSELPATLITCSELDPLRD
MSMEG_2568|M.smegmatis_MC2_155 TVAMWRHWLAG------RAAPDGAVPARATEISDMPAAFISCSELDPLRD
TH_2562|M.thermoresistible__bu CDQMWRHYLAG------AAPTAAAAPGRADDLTGAPPAFISCSELDPLRD
MMAR_0404|M.marinum_M ASLMWRHYLAG------QTPSPESVPGRRGQLAGLPATLITCGEIDPFRD
MUL_1054|M.ulcerans_Agy99 ASLMWRHYLAG------QTPSPESVPGRRGQLAGLPATLITCGEIDPFRD
MAV_1617|M.avium_104 VSRAWNHYLGH------ASASGQHVPAHRANLEGLPPTFISCSEIDPCRD
MLBr_00314|M.leprae_Br4923 FDALGRLVASSAAKNKVDDKPEELYEPLDHIAPGLPRTLIHVSGSEVLLH
* : * . : .
Mb1435c|M.bovis_AF2122/97 DGIRYGELLAAAGVPVEVHNAQTLVHGYVGYAGVVPAATEATNRGLVALR
Rv1400c|M.tuberculosis_H37Rv DGIRYGELLAAAGVPVEVHNAQTLVHGYVGYAGVVPAATEATNRGLVALR
MAB_3270c|M.abscessus_ATCC_199 EGNEYAAKLRAAGVPVDLRVQGPLIHGFYNMAGLGGAPSEAMNQLTSALR
Mflv_4102|M.gilvum_PYR-GCK EALDYALRLLWAGVAAELHVFSGTCHGFDSLVPEWEISRQLFDIQGTALR
Mvan_2244|M.vanbaalenii_PYR-1 EAIDYALRLMWSGVNTELHVFSGTCHGFDSLVPDWEVSSQLFDIQGAALR
MSMEG_2568|M.smegmatis_MC2_155 EALDHARRLIDGGVSTELHVFAGTCHGFDSLLPEWEVSQELFTLQGAALR
TH_2562|M.thermoresistible__bu EALDYAARLLRCGVPTELHLFPGTCHGFDSLLPEWELSRQLFALQAAAVR
MMAR_0404|M.marinum_M EVLDYAQRLLGAGVSTELHIFPRACHGFDSLLPEWTTSQRLFAMQGHALA
MUL_1054|M.ulcerans_Agy99 EVLDYAQRLLGAGVSTELHIFPRACHGFDSLLPEWTTSQRLFAMQGHALA
MAV_1617|M.avium_104 EAIDYANRLLHAYVHTELHVIAATFNGFDSMVPDWIVAQENRALHAQALR
MLBr_00314|M.leprae_Br4923 DAQLAATKLAAVGVPAEIRVWPGQVHVFQAAAPMVPEATLSLRQISQYIR
: . * * .::: : : . :
Mb1435c|M.bovis_AF2122/97 VVLHG---------
Rv1400c|M.tuberculosis_H37Rv VVLHG---------
MAB_3270c|M.abscessus_ATCC_199 AHLSR---------
Mflv_4102|M.gilvum_PYR-GCK RAFLR---------
Mvan_2244|M.vanbaalenii_PYR-1 RAFLG---------
MSMEG_2568|M.smegmatis_MC2_155 RALR----------
TH_2562|M.thermoresistible__bu RAFTTAEYPAGQVN
MMAR_0404|M.marinum_M DAFYPD--------
MUL_1054|M.ulcerans_Agy99 DAFYPD--------
MAV_1617|M.avium_104 RVFAM---------
MLBr_00314|M.leprae_Br4923 EATASKASRDRQSL