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KYQGRVVVVTGAGSGIGRALTQALTAGGAHVAASDIDDNGLAETQASCGPGQVTPYRIDVADRDAVLGFA DEVRRKHGPASMVFNNAGVDLFASVADMSWEDFDWLMGINVGGVVNGTKAFLPQLIEAGSDRRPSRLVNL SSAFGLIAVPYQGAYSTSKFAVRGFTEALRQEMIIERHPVTVHCVHPGVVRTNFGANMRTSDTEDPDLAA QLFDRAALTTPARAARLILRGAEKNRARILIGADGRAMAALPRLLGVAYAGLLARAARLTDSRAAHSGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1599 | - | - | 100% (280) | oxidoreductase, short chain dehydrogenase/reductase family protein |
| M. avium 104 | MAV_1384 | - | 2e-58 | 46.97% (264) | short chain alcohol dehydrogenase |
| M. avium 104 | MAV_1382 | - | 7e-58 | 46.24% (266) | short chain alcohol dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3112 | - | 3e-61 | 46.99% (266) | short-chain type dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_2216 | - | 1e-57 | 45.42% (273) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv3085 | - | 3e-61 | 46.99% (266) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01094 | - | 3e-53 | 42.80% (271) | short chain alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3919c | - | 5e-70 | 51.13% (266) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_4195 | - | 1e-59 | 46.21% (264) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_5053 | - | 5e-57 | 44.24% (269) | short chain alcohol dehydrogenase |
| M. thermoresistible (build 8) | TH_1828 | - | 3e-56 | 42.91% (275) | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE |
| M. ulcerans Agy99 | MUL_4501 | - | 6e-59 | 45.45% (264) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_4479 | - | 7e-61 | 46.52% (273) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5053|M.smegmatis_MC2_155 MEGFAGKVAVVTGAGSGIGQALAIELGRSGAKLAICDVDTEGLAATEERL
TH_1828|M.thermoresistible__bu MQGFAGKVAVITGAGSGIGQALALELGRSGAKVAISDVNTEGLTETEDRL
Mflv_2216|M.gilvum_PYR-GCK MQGFAGKVAVVTGAGSGIGQALAIELGRSGALVAISDVDTEGLAVTEERL
Mvan_4479|M.vanbaalenii_PYR-1 MEGFAGKVAVVTGAGSGIGQALAIELGRSGARVAISDVDTEGLAVTEERL
MMAR_4195|M.marinum_M MEGFAGKVAVVTGAGSGIGRALAIELARSGAKLAISDVDTEGLAQTEKLV
MUL_4501|M.ulcerans_Agy99 MEGFAGKVAVVTGAGSGIGRALAIELARSGAKLAISDVDTEGLAQTEKLV
MLBr_01094|M.leprae_Br4923 MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEGLAQTEGQL
Mb3112|M.bovis_AF2122/97 MSSFEGKVAVITGAGSGIGRALALNLSEKRAKLALSDVDTDGLAKTVRLA
Rv3085|M.tuberculosis_H37Rv MSSFEGKVAVITGAGSGIGRALALNLSEKRAKLALSDVDTDGLAKTVRLA
MAB_3919c|M.abscessus_ATCC_199 MKNFDNKVAVITGAGSGIGRSLALALAQRGARLALSDIDTAGVADTAGRC
MAV_1599|M.avium_104 MK-YQGRVVVVTGAGSGIGRALTQALTAGGAHVAASDIDDNGLAETQASC
*. : .:*.*:********::*: * * :* .*:: *:: *
MSMEG_5053|M.smegmatis_MC2_155 KAIGAPVKADRLDVTEREAFLLYADAVKEHYGTVNQIYNNAGIAFTGDVE
TH_1828|M.thermoresistible__bu KAIGAPVKADRLDVTERAAFEAYADAVVEHFGVVNQIYNNAGIAYTGDIE
Mflv_2216|M.gilvum_PYR-GCK KAIGTHVKSDRLNVTERERFLQYADDVAEHFGKVHQIYNNAGIAFTGDIE
Mvan_4479|M.vanbaalenii_PYR-1 KAIGAQVKSDRLDVTERETFLLYADDVAEHFGSVNQIYNNAGIAFTGDIE
MMAR_4195|M.marinum_M TALGAEVKTDRLDVTEREAFLAYADAVNEHFGKVNQIYNNAGIGHTGDVE
MUL_4501|M.ulcerans_Agy99 TALGAEVKTDRLDVTERETFLAYADAVNEHFGKVNQIYNNAGIGHTGDVE
MLBr_01094|M.leprae_Br4923 KAIGASARTDRLDVTEREAFLTYADVVHENFGKVNQIYNNAGIAFTGDVE
Mb3112|M.bovis_AF2122/97 QALGAQVKSDRLDVAEREAVLAHADAVVAHFGTVHQVYNNAGIAYNGNVD
Rv3085|M.tuberculosis_H37Rv QALGAQVKSDRLDVAEREAVLAHADAVVAHFGTVHQVYNNAGIAYNGNVD
MAB_3919c|M.abscessus_ATCC_199 EKAGATAIPFELDVADRAAVYAHAADVKNEFGQVNLVFNNAGVALSADVK
MAV_1599|M.avium_104 GPG--QVTPYRIDVADRDAVLGFADEVRRKHGPASMVFNNAGVDLFASVA
. . .::*::* . .* * ..* . ::****: ..:
MSMEG_5053|M.smegmatis_MC2_155 ISEFKDIERVMDVDYWGVVNGTKAFLPHLIASGD----GHVINVSSVFGL
TH_1828|M.thermoresistible__bu VSHFKDIERVMDVDFWGVVNGTKVFLPHLIASGD----GHVINISSVFGL
Mflv_2216|M.gilvum_PYR-GCK VSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGD----GHVVNVSSVFGL
Mvan_4479|M.vanbaalenii_PYR-1 ITQFKDIERVMDVDYWGVVNGTKAFLPHLIASGD----GHVVNVSSVFGL
MMAR_4195|M.marinum_M VCAFKDIDRVMDVDFGGVLNGTKAFLPYLIASGD----GHVINVSSVFGL
MUL_4501|M.ulcerans_Agy99 VCAFKDIDRVMDVDFGGVLNGTKTFLPYLIASGD----GHVINVSSVFGL
MLBr_01094|M.leprae_Br4923 VSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGD----GHVINISSVFGL
Mb3112|M.bovis_AF2122/97 KSEFKDIERIIDVDFWGVVNGTKAFLPHVIASGD----GHIVNISSLFGL
Rv3085|M.tuberculosis_H37Rv KSEFKDIERIIDVDFWGVVNGTKAFLPHVIASGD----GHIVNISSLFGL
MAB_3919c|M.abscessus_ATCC_199 DMEWDDFDWLMNINFWGVAHGTKAFLPHLIESGD----GHIVNVSSVFGL
MAV_1599|M.avium_104 DMSWEDFDWLMGINVGGVVNGTKAFLPQLIEAGSDRRPSRLVNLSSAFGL
:.*:: ::.:: ** :***.*** :* :*. .:::*:** ***
MSMEG_5053|M.smegmatis_MC2_155 FSVPGQAAYNSAKFAVRGFTEALRQEMAIAKHPVKVTTVHPGGIKTAIAR
TH_1828|M.thermoresistible__bu FSVPGQAAYNAAKFAVRGFTEALRQEMILAGHPVKVTTVHPGGIKTGIAR
Mflv_2216|M.gilvum_PYR-GCK FSVPGQGAYNAAKFAVRGFTEALRQEMALAGHPVKVSCVHPGGIKTAIAR
Mvan_4479|M.vanbaalenii_PYR-1 FSVPGQAAYNSAKFAVRGFTEALRQEMALAGHPVKVSCVHPGGIKTAIAR
MMAR_4195|M.marinum_M FSVSGQAAYNAAKFAVRGFTEALRQEMILAGHPVGVTTVHPGGIKTAIAR
MUL_4501|M.ulcerans_Agy99 FSVSGQAAYNAAKFAVRGFTEALRQEMILAGHPVGVTTVHPGGIKTAIAR
MLBr_01094|M.leprae_Br4923 FSVPGQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYPGGIKTAIAR
Mb3112|M.bovis_AF2122/97 IAVPGQSAYNAAKFAVRGFTEALRQEMLVARHPVKVTCVHPGGIKTAVAR
Rv3085|M.tuberculosis_H37Rv IAVPGQSAYNAAKFAVRGFTEALRQEMLVARHPVKVTCVHPGGIKTAVAR
MAB_3919c|M.abscessus_ATCC_199 MGIPSQSAYNAAKFAVRGFTESLRQEIRAAKFPVGVTCVHPGGIKTNIAS
MAV_1599|M.avium_104 IAVPYQGAYSTSKFAVRGFTEALRQEMIIERHPVTVHCVHPGVVRTNFGA
:.:. *.**.::*********:**:*: ** * *:** ::* ..
MSMEG_5053|M.smegmatis_MC2_155 NAT-AAEGLDAKELAEAFDKKLANTTPQRAAVIILDGVRKNKARVLVGPD
TH_1828|M.thermoresistible__bu NMT-AAEGLDAQELARAFDTKLARTSPEKAAQIILDGVRKNKARVLVGTD
Mflv_2216|M.gilvum_PYR-GCK NAG-AAEGLDAEELAKTFDKKLASTTPEKAAQVILDGVRKNKARILIGND
Mvan_4479|M.vanbaalenii_PYR-1 NAS-AAEGLDAEELAKAFDKKLASTTPEKAAKIILDGVRKNRARILVGND
MMAR_4195|M.marinum_M NAT-AAEGLDSDELAKMFDKRVARTSPERAAKIILGAVRKNKARVLVGPD
MUL_4501|M.ulcerans_Agy99 NAT-AAEGLDSDELAKMFDKRVARTSPERAAKIILGAVRKNKARVLVGPD
MLBr_01094|M.leprae_Br4923 NAT-AAEGLDVSKIASRFDTWVAHTSPQHAARIILKAVRKKKARVLVGPD
Mb3112|M.bovis_AF2122/97 NAT-VADGEDQQTFAEFFDRRLALHSPEMAAKTIVNGVAKGQARVVVGLE
Rv3085|M.tuberculosis_H37Rv NAT-VADGEDQQTFAEFFDRRLALHSPEMAAKTIVNGVAKGQARVVVGLE
MAB_3919c|M.abscessus_ATCC_199 SARGIPDGVDRETVRKGFQ-LMAITRPDSAARIILRGVEKNRPRVLIGPD
MAV_1599|M.avium_104 NMR-TSDTEDPDLAAQLFD-RAALTTPARAARLILRGAEKNRARILIGAD
. .: * . *: * * ** *: .. * :.*:::* :
MSMEG_5053|M.smegmatis_MC2_155 AKILDVIVRITG-SGYQRLFSAV--AAKAMPR-----------
TH_1828|M.thermoresistible__bu AKILDAIVRLTG-SGYQRLFPKF--VARTMPR-----------
Mflv_2216|M.gilvum_PYR-GCK AKMFEIAIRALG-AGYQSVFPKV--VARLTPPAK---------
Mvan_4479|M.vanbaalenii_PYR-1 AKVFDVVVRVLG-AGYQSLFPKA--VARLTPPAK---------
MMAR_4195|M.marinum_M AKALDIVVRLTG-SGYQRLFMPV--LGRLVPASHR--------
MUL_4501|M.ulcerans_Agy99 AKALDIVVRLTG-SGYQRLFMPV--LGRLVPASHR--------
MLBr_01094|M.leprae_Br4923 AKVANVVVRFSGGAGYQRLFAQV--ASRLILNQR---------
Mb3112|M.bovis_AF2122/97 AKAVDVLARIMG-SSYQRLVAAG--VAKFFPWAK---------
Rv3085|M.tuberculosis_H37Rv AKAVDVLARIMG-SSYQRLVAAG--VAKFFPWAK---------
MAB_3919c|M.abscessus_ATCC_199 ARVFDAIPRIIG-PRYEDLMAPFYGMGRYGIGKKIAGRFGIEL
MAV_1599|M.avium_104 GRAMAALPRLLG-VAYAGLLARA---ARLTDSRAAHSGR----
.: * * * :. .: