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MSSFEGKVAVITGAGSGIGRALALNLSEKRAKLALSDVDTDGLAKTVRLAQALGAQVKSDRLDVAEREAV LAHADAVVAHFGTVHQVYNNAGIAYNGNVDKSEFKDIERIIDVDFWGVVNGTKAFLPHVIASGDGHIVNI SSLFGLIAVPGQSAYNAAKFAVRGFTEALRQEMLVARHPVKVTCVHPGGIKTAVARNATVADGEDQQTFA EFFDRRLALHSPEMAAKTIVNGVAKGQARVVVGLEAKAVDVLARIMGSSYQRLVAAGVAKFFPWAK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3112 | - | - | 100% (276) | short-chain type dehydrogenase/reductase |
| M. bovis AF2122 / 97 | Mb1277c | - | e-103 | 65.20% (273) | short-chain type dehydrogenase/reductase |
| M. bovis AF2122 / 97 | Mb3083c | - | 2e-37 | 36.26% (273) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2216 | - | 9e-99 | 62.32% (276) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv3085 | - | 1e-153 | 100.00% (276) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01094 | - | 7e-90 | 61.28% (266) | short chain alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1388c | - | 1e-101 | 66.67% (261) | short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4195 | - | 1e-100 | 64.84% (273) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1384 | - | 1e-102 | 65.57% (273) | short chain alcohol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5053 | - | 1e-103 | 66.67% (273) | short chain alcohol dehydrogenase |
| M. thermoresistible (build 8) | TH_1828 | - | 1e-101 | 65.93% (273) | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE |
| M. ulcerans Agy99 | MUL_4501 | - | 4e-99 | 64.10% (273) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_4479 | - | 1e-102 | 63.77% (276) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4195|M.marinum_M MEGFAGKVAVVTGAGSGIGRALAIELARSGAKLAISDVDTEGLAQTEKLV
MUL_4501|M.ulcerans_Agy99 MEGFAGKVAVVTGAGSGIGRALAIELARSGAKLAISDVDTEGLAQTEKLV
MLBr_01094|M.leprae_Br4923 MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEGLAQTEGQL
MAV_1384|M.avium_104 MQGFAGKVAVVTGAGSGIGQALAVELARSGAKVAISDVDLEGLAHTEEQL
Mflv_2216|M.gilvum_PYR-GCK MQGFAGKVAVVTGAGSGIGQALAIELGRSGALVAISDVDTEGLAVTEERL
Mvan_4479|M.vanbaalenii_PYR-1 MEGFAGKVAVVTGAGSGIGQALAIELGRSGARVAISDVDTEGLAVTEERL
TH_1828|M.thermoresistible__bu MQGFAGKVAVITGAGSGIGQALALELGRSGAKVAISDVNTEGLTETEDRL
MSMEG_5053|M.smegmatis_MC2_155 MEGFAGKVAVVTGAGSGIGQALAIELGRSGAKLAICDVDTEGLAATEERL
MAB_1388c|M.abscessus_ATCC_199 MEGFSGKVAVVTGAGSGIGRALAVELARSGAKIAISDIDNEGLAETERQV
Mb3112|M.bovis_AF2122/97 MSSFEGKVAVITGAGSGIGRALALNLSEKRAKLALSDVDTDGLAKTVRLA
Rv3085|M.tuberculosis_H37Rv MSSFEGKVAVITGAGSGIGRALALNLSEKRAKLALSDVDTDGLAKTVRLA
*..* *****:********:***::*... * :*:.*:: :**: *
MMAR_4195|M.marinum_M TALGAEVKTDRLDVTEREAFLAYADAVNEHFGKVNQIYNNAGIGHTGDVE
MUL_4501|M.ulcerans_Agy99 TALGAEVKTDRLDVTERETFLAYADAVNEHFGKVNQIYNNAGIGHTGDVE
MLBr_01094|M.leprae_Br4923 KAIGASARTDRLDVTEREAFLTYADVVHENFGKVNQIYNNAGIAFTGDVE
MAV_1384|M.avium_104 KAIGAQYKADRLDVTEREAFLAYADAVKEHFGKVNQIYNNAGIAFTGDVE
Mflv_2216|M.gilvum_PYR-GCK KAIGTHVKSDRLNVTERERFLQYADDVAEHFGKVHQIYNNAGIAFTGDIE
Mvan_4479|M.vanbaalenii_PYR-1 KAIGAQVKSDRLDVTERETFLLYADDVAEHFGSVNQIYNNAGIAFTGDIE
TH_1828|M.thermoresistible__bu KAIGAPVKADRLDVTERAAFEAYADAVVEHFGVVNQIYNNAGIAYTGDIE
MSMEG_5053|M.smegmatis_MC2_155 KAIGAPVKADRLDVTEREAFLLYADAVKEHYGTVNQIYNNAGIAFTGDVE
MAB_1388c|M.abscessus_ATCC_199 KALGAEVRADRLNVAEREAFLLYADAIKDHFGKVNQIYNNAGIAYQGEVE
Mb3112|M.bovis_AF2122/97 QALGAQVKSDRLDVAEREAVLAHADAVVAHFGTVHQVYNNAGIAYNGNVD
Rv3085|M.tuberculosis_H37Rv QALGAQVKSDRLDVAEREAVLAHADAVVAHFGTVHQVYNNAGIAYNGNVD
*:*: ::***:*:** . :** : ::* *:*:******.. *:::
MMAR_4195|M.marinum_M VCAFKDIDRVMDVDFGGVLNGTKAFLPYLIASGDGHVINVSSVFGLFSVS
MUL_4501|M.ulcerans_Agy99 VCAFKDIDRVMDVDFGGVLNGTKTFLPYLIASGDGHVINVSSVFGLFSVS
MLBr_01094|M.leprae_Br4923 VSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGDGHVINISSVFGLFSVP
MAV_1384|M.avium_104 VSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVVNVSSVFGLFSVP
Mflv_2216|M.gilvum_PYR-GCK VSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVVNVSSVFGLFSVP
Mvan_4479|M.vanbaalenii_PYR-1 ITQFKDIERVMDVDYWGVVNGTKAFLPHLIASGDGHVVNVSSVFGLFSVP
TH_1828|M.thermoresistible__bu VSHFKDIERVMDVDFWGVVNGTKVFLPHLIASGDGHVINISSVFGLFSVP
MSMEG_5053|M.smegmatis_MC2_155 ISEFKDIERVMDVDYWGVVNGTKAFLPHLIASGDGHVINVSSVFGLFSVP
MAB_1388c|M.abscessus_ATCC_199 ESQFKDIERIIDVDFWGVVNGTKAFLPHLIASGDGHVVNVSSLFGVLSMP
Mb3112|M.bovis_AF2122/97 KSEFKDIERIIDVDFWGVVNGTKAFLPHVIASGDGHIVNISSLFGLIAVP
Rv3085|M.tuberculosis_H37Rv KSEFKDIERIIDVDFWGVVNGTKAFLPHVIASGDGHIVNISSLFGLIAVP
****:*::***: **:****.***::*:*****::*:**:**::::.
MMAR_4195|M.marinum_M GQAAYNAAKFAVRGFTEALRQEMILAGHPVGVTTVHPGGIKTAIARNATA
MUL_4501|M.ulcerans_Agy99 GQAAYNAAKFAVRGFTEALRQEMILAGHPVGVTTVHPGGIKTAIARNATA
MLBr_01094|M.leprae_Br4923 GQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYPGGIKTAIARNATA
MAV_1384|M.avium_104 GQAAYNSAKFAVRGFTEALRQEMAAAGHPVAVTTVHPGGIKTAIARNATA
Mflv_2216|M.gilvum_PYR-GCK GQGAYNAAKFAVRGFTEALRQEMALAGHPVKVSCVHPGGIKTAIARNAGA
Mvan_4479|M.vanbaalenii_PYR-1 GQAAYNSAKFAVRGFTEALRQEMALAGHPVKVSCVHPGGIKTAIARNASA
TH_1828|M.thermoresistible__bu GQAAYNAAKFAVRGFTEALRQEMILAGHPVKVTTVHPGGIKTGIARNMTA
MSMEG_5053|M.smegmatis_MC2_155 GQAAYNSAKFAVRGFTEALRQEMAIAKHPVKVTTVHPGGIKTAIARNATA
MAB_1388c|M.abscessus_ATCC_199 GQSAYNSAKFAVRGFTESLRQEMIIGKKPVAVTCVHPGGIKTAIARNSTT
Mb3112|M.bovis_AF2122/97 GQSAYNAAKFAVRGFTEALRQEMLVARHPVKVTCVHPGGIKTAVARNATV
Rv3085|M.tuberculosis_H37Rv GQSAYNAAKFAVRGFTEALRQEMLVARHPVKVTCVHPGGIKTAVARNATV
**.***:**********:**:** . :** *: *:******.:*** .
MMAR_4195|M.marinum_M AEGLDSDELAKMFDKRVARTSPERAAKIILGAVRKNKARVLVGPDAKALD
MUL_4501|M.ulcerans_Agy99 AEGLDSDELAKMFDKRVARTSPERAAKIILGAVRKNKARVLVGPDAKALD
MLBr_01094|M.leprae_Br4923 AEGLDVSKIASRFDTWVAHTSPQHAARIILKAVRKKKARVLVGPDAKVAN
MAV_1384|M.avium_104 AEGLDQAELAKLFDKRLAKTTPQRAAQIILDAVRKKKARVLVGSDAKALD
Mflv_2216|M.gilvum_PYR-GCK AEGLDAEELAKTFDKKLASTTPEKAAQVILDGVRKNKARILIGNDAKMFE
Mvan_4479|M.vanbaalenii_PYR-1 AEGLDAEELAKAFDKKLASTTPEKAAKIILDGVRKNRARILVGNDAKVFD
TH_1828|M.thermoresistible__bu AEGLDAQELARAFDTKLARTSPEKAAQIILDGVRKNKARVLVGTDAKILD
MSMEG_5053|M.smegmatis_MC2_155 AEGLDAKELAEAFDKKLANTTPQRAAVIILDGVRKNKARVLVGPDAKILD
MAB_1388c|M.abscessus_ATCC_199 AEGYDQQAMAAMFDKYLANTSPEAAARIILTAVRKKKPRVLVGPDAKILD
Mb3112|M.bovis_AF2122/97 ADGEDQQTFAEFFDRRLALHSPEMAAKTIVNGVAKGQARVVVGLEAKAVD
Rv3085|M.tuberculosis_H37Rv ADGEDQQTFAEFFDRRLALHSPEMAAKTIVNGVAKGQARVVVGLEAKAVD
*:* * :* ** :* :*: ** *: .* * :.*:::* :** :
MMAR_4195|M.marinum_M IVVRLTG-SGYQRLFMPVLGRLVPASHR-
MUL_4501|M.ulcerans_Agy99 IVVRLTG-SGYQRLFMPVLGRLVPASHR-
MLBr_01094|M.leprae_Br4923 VVVRFSGGAGYQRLFAQVASRLILNQR--
MAV_1384|M.avium_104 ILVRLTG-SGYQRLFGPVMSRLLPN----
Mflv_2216|M.gilvum_PYR-GCK IAIRALG-AGYQSVFPKVVARLTPPAK--
Mvan_4479|M.vanbaalenii_PYR-1 VVVRVLG-AGYQSLFPKAVARLTPPAK--
TH_1828|M.thermoresistible__bu AIVRLTG-SGYQRLFPKFVARTMPR----
MSMEG_5053|M.smegmatis_MC2_155 VIVRITG-SGYQRLFSAVAAKAMPR----
MAB_1388c|M.abscessus_ATCC_199 VIVRLTG-ARYQDIFSVVTRFILPRPGKK
Mb3112|M.bovis_AF2122/97 VLARIMG-SSYQRLVAAGVAKFFPWAK--
Rv3085|M.tuberculosis_H37Rv VLARIMG-SSYQRLVAAGVAKFFPWAK--
* * : ** :.