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QGFAGKVAVVTGAGSGIGQALAVELGRAGAKLAISDVDTAGLAQTAEQLAAIGAPVKADRLDVTEREAFL AYADAVNEHYGRVNQIYNNAGITFIGSIEDSRFKDIERVVDVDFWGVVNGTKAFLPHLIASGDGHVINIS SALGLFSAPGQAAYVSAKFAVRGFTEALHQEMLRAGHPVRVTTVHPGGIKTAFARNATGVEGLDHAELAS LFEEQQAKTTPQRAAQLILDGVRRNKARVLVGPDVKAMDLLVRAAGPNYERLLAGPVMGRVKEFVTRLLP KR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1382 | - | - | 100% (283) | short chain alcohol dehydrogenase |
| M. avium 104 | MAV_1384 | - | e-119 | 79.41% (272) | short chain alcohol dehydrogenase |
| M. avium 104 | MAV_1599 | - | 7e-58 | 46.24% (266) | oxidoreductase, short chain dehydrogenase/reductase family |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1277c | - | 1e-114 | 77.95% (263) | short-chain type dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_2216 | - | 1e-107 | 72.80% (261) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1245c | - | 1e-114 | 77.95% (263) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01094 | - | 1e-105 | 71.80% (266) | short chain alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_1388c | - | 1e-101 | 65.28% (265) | short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4195 | - | 1e-111 | 73.16% (272) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_5053 | - | 1e-116 | 78.49% (265) | short chain alcohol dehydrogenase |
| M. thermoresistible (build 8) | TH_1828 | - | 1e-112 | 71.99% (282) | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE |
| M. ulcerans Agy99 | MUL_4501 | - | 1e-110 | 72.43% (272) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_4479 | - | 1e-109 | 73.38% (263) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4195|M.marinum_M MEGFAGKVAVVTGAGSGIGRALAIELARSGAKLAISDVDTEGLAQTEKLV
MUL_4501|M.ulcerans_Agy99 MEGFAGKVAVVTGAGSGIGRALAIELARSGAKLAISDVDTEGLAQTEKLV
MAB_1388c|M.abscessus_ATCC_199 MEGFSGKVAVVTGAGSGIGRALAVELARSGAKIAISDIDNEGLAETERQV
MLBr_01094|M.leprae_Br4923 MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEGLAQTEGQL
Mb1277c|M.bovis_AF2122/97 MEGFAGKVAVVTGAGSGIGQALAIELARSGAKVAISDVDTDGLADTEHRL
Rv1245c|M.tuberculosis_H37Rv MEGFAGKVAVVTGAGSGIGQALAIELARSGAKVAISDVDTDGLADTEHRL
Mflv_2216|M.gilvum_PYR-GCK MQGFAGKVAVVTGAGSGIGQALAIELGRSGALVAISDVDTEGLAVTEERL
Mvan_4479|M.vanbaalenii_PYR-1 MEGFAGKVAVVTGAGSGIGQALAIELGRSGARVAISDVDTEGLAVTEERL
TH_1828|M.thermoresistible__bu MQGFAGKVAVITGAGSGIGQALALELGRSGAKVAISDVNTEGLTETEDRL
MSMEG_5053|M.smegmatis_MC2_155 MEGFAGKVAVVTGAGSGIGQALAIELGRSGAKLAICDVDTEGLAATEERL
MAV_1382|M.avium_104 MQGFAGKVAVVTGAGSGIGQALAVELGRAGAKLAISDVDTAGLAQTAEQL
*:**:*****:********:***:**.*:** :**.*:: **: * :
MMAR_4195|M.marinum_M TALGAEVKTDRLDVTEREAFLAYADAVNEHFGKVNQIYNNAGIGHTGDVE
MUL_4501|M.ulcerans_Agy99 TALGAEVKTDRLDVTERETFLAYADAVNEHFGKVNQIYNNAGIGHTGDVE
MAB_1388c|M.abscessus_ATCC_199 KALGAEVRADRLNVAEREAFLLYADAIKDHFGKVNQIYNNAGIAYQGEVE
MLBr_01094|M.leprae_Br4923 KAIGASARTDRLDVTEREAFLTYADVVHENFGKVNQIYNNAGIAFTGDVE
Mb1277c|M.bovis_AF2122/97 KAISTPVKTDRLDVTEREAFLAYADAVNEHFGTVNQIYNNAGIAFTGDIE
Rv1245c|M.tuberculosis_H37Rv KAISTPVKTDRLDVTEREAFLAYADAVNEHFGTVNQIYNNAGIAFTGDIE
Mflv_2216|M.gilvum_PYR-GCK KAIGTHVKSDRLNVTERERFLQYADDVAEHFGKVHQIYNNAGIAFTGDIE
Mvan_4479|M.vanbaalenii_PYR-1 KAIGAQVKSDRLDVTERETFLLYADDVAEHFGSVNQIYNNAGIAFTGDIE
TH_1828|M.thermoresistible__bu KAIGAPVKADRLDVTERAAFEAYADAVVEHFGVVNQIYNNAGIAYTGDIE
MSMEG_5053|M.smegmatis_MC2_155 KAIGAPVKADRLDVTEREAFLLYADAVKEHYGTVNQIYNNAGIAFTGDVE
MAV_1382|M.avium_104 AAIGAPVKADRLDVTEREAFLAYADAVNEHYGRVNQIYNNAGITFIGSIE
*:.: .::***:*:** * *** : :::* *:******** . *.:*
MMAR_4195|M.marinum_M VCAFKDIDRVMDVDFGGVLNGTKAFLPYLIASGDGHVINVSSVFGLFSVS
MUL_4501|M.ulcerans_Agy99 VCAFKDIDRVMDVDFGGVLNGTKTFLPYLIASGDGHVINVSSVFGLFSVS
MAB_1388c|M.abscessus_ATCC_199 ESQFKDIERIIDVDFWGVVNGTKAFLPHLIASGDGHVVNVSSLFGVLSMP
MLBr_01094|M.leprae_Br4923 VSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGDGHVINISSVFGLFSVP
Mb1277c|M.bovis_AF2122/97 VSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVINISSVFGLFSAP
Rv1245c|M.tuberculosis_H37Rv VSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVINISSVFGLFSAP
Mflv_2216|M.gilvum_PYR-GCK VSQFKDIERVMDVDFWGVVNGTKAFLPHLIASGDGHVVNVSSVFGLFSVP
Mvan_4479|M.vanbaalenii_PYR-1 ITQFKDIERVMDVDYWGVVNGTKAFLPHLIASGDGHVVNVSSVFGLFSVP
TH_1828|M.thermoresistible__bu VSHFKDIERVMDVDFWGVVNGTKVFLPHLIASGDGHVINISSVFGLFSVP
MSMEG_5053|M.smegmatis_MC2_155 ISEFKDIERVMDVDYWGVVNGTKAFLPHLIASGDGHVINVSSVFGLFSVP
MAV_1382|M.avium_104 DSRFKDIERVVDVDFWGVVNGTKAFLPHLIASGDGHVINISSALGLFSAP
****:*::***: **:****.***:**:******:*:** :*::* .
MMAR_4195|M.marinum_M GQAAYNAAKFAVRGFTEALRQEMILAGHPVGVTTVHPGGIKTAIARNATA
MUL_4501|M.ulcerans_Agy99 GQAAYNAAKFAVRGFTEALRQEMILAGHPVGVTTVHPGGIKTAIARNATA
MAB_1388c|M.abscessus_ATCC_199 GQSAYNSAKFAVRGFTESLRQEMIIGKKPVAVTCVHPGGIKTAIARNSTT
MLBr_01094|M.leprae_Br4923 GQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYPGGIKTAIARNATA
Mb1277c|M.bovis_AF2122/97 GQAAYNSAKFAVRGFTEALRQEMALAGHPVKVTTVHPGGVKTAIARNATA
Rv1245c|M.tuberculosis_H37Rv GQAAYNSAKFAVRGFTEALRQEMALAGHPVKVTTVHPGGVKTAIARNATA
Mflv_2216|M.gilvum_PYR-GCK GQGAYNAAKFAVRGFTEALRQEMALAGHPVKVSCVHPGGIKTAIARNAGA
Mvan_4479|M.vanbaalenii_PYR-1 GQAAYNSAKFAVRGFTEALRQEMALAGHPVKVSCVHPGGIKTAIARNASA
TH_1828|M.thermoresistible__bu GQAAYNAAKFAVRGFTEALRQEMILAGHPVKVTTVHPGGIKTGIARNMTA
MSMEG_5053|M.smegmatis_MC2_155 GQAAYNSAKFAVRGFTEALRQEMAIAKHPVKVTTVHPGGIKTAIARNATA
MAV_1382|M.avium_104 GQAAYVSAKFAVRGFTEALHQEMLRAGHPVRVTTVHPGGIKTAFARNATG
**.** :**********:*::** . :** *: *:***:**.:***
MMAR_4195|M.marinum_M AEGLDSDELAKMFDKRVARTSPERAAKIILGAVRKNKARVLVGPDAKALD
MUL_4501|M.ulcerans_Agy99 AEGLDSDELAKMFDKRVARTSPERAAKIILGAVRKNKARVLVGPDAKALD
MAB_1388c|M.abscessus_ATCC_199 AEGYDQQAMAAMFDKYLANTSPEAAARIILTAVRKKKPRVLVGPDAKILD
MLBr_01094|M.leprae_Br4923 AEGLDVSKIASRFDTWVAHTSPQHAARIILKAVRKKKARVLVGPDAKVAN
Mb1277c|M.bovis_AF2122/97 AEGLDQAELAETFDKRVAHLSPQRAAQIILTGVAKNKARVLVGVDAKVLD
Rv1245c|M.tuberculosis_H37Rv AEGLDQAELAETFDKRVAHLSPQRAAQIILTGVAKNKARVLVGVDAKVLD
Mflv_2216|M.gilvum_PYR-GCK AEGLDAEELAKTFDKKLASTTPEKAAQVILDGVRKNKARILIGNDAKMFE
Mvan_4479|M.vanbaalenii_PYR-1 AEGLDAEELAKAFDKKLASTTPEKAAKIILDGVRKNRARILVGNDAKVFD
TH_1828|M.thermoresistible__bu AEGLDAQELARAFDTKLARTSPEKAAQIILDGVRKNKARVLVGTDAKILD
MSMEG_5053|M.smegmatis_MC2_155 AEGLDAKELAEAFDKKLANTTPQRAAVIILDGVRKNKARVLVGPDAKILD
MAV_1382|M.avium_104 VEGLDHAELASLFEEQQAKTTPQRAAQLILDGVRRNKARVLVGPDVKAMD
.** * :* *: * :*: ** :** .* :::.*:*:* *.* :
MMAR_4195|M.marinum_M IVVRLTG-SGYQRLFM--------PVLGRLVPASHR-
MUL_4501|M.ulcerans_Agy99 IVVRLTG-SGYQRLFM--------PVLGRLVPASHR-
MAB_1388c|M.abscessus_ATCC_199 VIVRLTG-ARYQDIFS--------VVTRFILPRPGKK
MLBr_01094|M.leprae_Br4923 VVVRFSGGAGYQRLFA--------QVASRLILNQR--
Mb1277c|M.bovis_AF2122/97 LVVRLTG-SGYQRIFP--------IITGRLIPRPR--
Rv1245c|M.tuberculosis_H37Rv LVVRLTG-SGYQRIFP--------IITGRLIPRPR--
Mflv_2216|M.gilvum_PYR-GCK IAIRALG-AGYQSVFP--------KVVARLTPPAK--
Mvan_4479|M.vanbaalenii_PYR-1 VVVRVLG-AGYQSLFP--------KAVARLTPPAK--
TH_1828|M.thermoresistible__bu AIVRLTG-SGYQRLFP--------KFVARTMPR----
MSMEG_5053|M.smegmatis_MC2_155 VIVRITG-SGYQRLFS--------AVAAKAMPR----
MAV_1382|M.avium_104 LLVRAAG-PNYERLLAGPVMGRVKEFVTRLLPKR---
:* * . *: ::