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ARDDWLVGRDRRSAAAERIYAAAADLIARRGYDGFTIEALAARVHCSPATIYRHAGGKATIRDAVVGIQA ARIVDTTREAIKDLRGPERVVTATIMALERLRSDPLAQLMRSIHAAPVSDWVINSPTVTALAAEMLGPGH DNPLAAQWLIRVFLALWGWPLKDPAAERALVHRFLGASYRPGGERDSICGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0009 | - | - | 100% (192) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1403 | - | 3e-16 | 31.28% (179) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1159 | - | 4e-08 | 26.67% (180) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1805c | - | 2e-42 | 49.16% (179) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3474 | - | 6e-63 | 63.69% (179) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1776c | - | 2e-42 | 49.16% (179) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1938c | - | 3e-26 | 35.26% (173) | TetR family transcriptional regulator |
| M. marinum M | MMAR_2651 | - | 2e-41 | 48.00% (175) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_0676 | - | 5e-46 | 53.98% (176) | putative transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_0937 | - | 4e-43 | 48.33% (180) | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_3128 | - | 8e-42 | 48.57% (175) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3780 | - | 3e-49 | 56.32% (174) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0009|M.avium_104 ----------MARDDWLVGRDRRSAAAERIYAAAADLIARRGYDGFTIEA
Mflv_3474|M.gilvum_PYR-GCK MSSPRAGDRPKATPDWLIGRDRRSEGAERIYVAAADLMARRGYDGFGIDA
Mvan_3780|M.vanbaalenii_PYR-1 -----------MRDDWLVG-DRRAEAADRIFSAATDLIVRDGLDGFDMAA
MSMEG_0676|M.smegmatis_MC2_155 ------------MADWLLGGDRRTAAAERIYAAATELVLRDGLDAFDIDT
TH_0937|M.thermoresistible__bu ----------VARTDWLVG-DRHDAAAERIYAAATELVLRRGLDALDVDT
Mb1805c|M.bovis_AF2122/97 ----------MPGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDK
Rv1776c|M.tuberculosis_H37Rv ----------MPGNDWIVGGNRRTIAAERIYAAATDLITRYGLNALDIDK
MMAR_2651|M.marinum_M ----------MPNDDWLVGGDRRRAAADRIYDAATDLIAHEGINQLDIDR
MUL_3128|M.ulcerans_Agy99 ----------MPNDDWLVGGDRRRAAADRIYDAATDLIAHEGINQLDIDR
MAB_1938c|M.abscessus_ATCC_199 ---------MSPYADWLHGSDRHTIAADRIVSVAAKQIARHGLDRLNLDA
**: * :*: .*:** .*:. : : * : : :
MAV_0009|M.avium_104 LAARVHCSPATIYRHAGGKATIRDAVVGIQAARIVDTTREAIKDLRGPER
Mflv_3474|M.gilvum_PYR-GCK LAAAVHCSPATIYRHVGGKSAIRDVVLERQAEHVLDSVRQAIAGLEGSER
Mvan_3780|M.vanbaalenii_PYR-1 LQAAVHCSRATIYRHVGGKAQIREAVLLRQAERIIATVRSAVVGLSGAER
MSMEG_0676|M.smegmatis_MC2_155 LAARVHCSRATVYRYAGGKAQIRDAVLLRLAASIVDSVRQAVGHLSGRER
TH_0937|M.thermoresistible__bu LAARVHCSRATVYRYTGGKAKIRDVVLTRLAAGIVETVRRAVDGLHGQDR
Mb1805c|M.bovis_AF2122/97 LAREVHCSRATIYRRAGGKAQIRDVVLTRAAARIADGVRSDVETLRGRER
Rv1776c|M.tuberculosis_H37Rv LAREVHCSRATIYRRAGGKAQIRDVVLTRAAARIADGVRSDVETLRGRER
MMAR_2651|M.marinum_M LATLVHCSRATVYRYVGGKNDIRNVVVKRAAARIADSVRSAVENLSGRER
MUL_3128|M.ulcerans_Agy99 LATLVHCSRATVYRYVGGKNDIRNVVVKRAAARIADSVRSAVENLSGRER
MAB_1938c|M.abscessus_ATCC_199 VAREAGCSRATVYRHVGGKTAIVDAVLARNIAKVTADIQRAVQSADARRR
: . ** **:** .*** * :.*: : : : . *
MAV_0009|M.avium_104 VVTATIMALERLRSDPLAQLMRS--IHAAPVSDWVINSPTVTALAAEMLG
Mflv_3474|M.gilvum_PYR-GCK IVTATLVALQRMRAAPLAEVMRS--MPGPPGTGWLIDSPVVARLAAEMVG
Mvan_3780|M.vanbaalenii_PYR-1 TVTAVVVALERIRADPIGQTLLS--AMRKDELTWIGRSAVPPALAAELTG
MSMEG_0676|M.smegmatis_MC2_155 VVRAVTVALEHIRSDPIRQMMVG--LGAGRDLSELPASPVLADLAAELTG
TH_0937|M.thermoresistible__bu IVTAITVALEQIRSAPLRRVMLT--ADNSPDVGELHESPALSRLAAELTG
Mb1805c|M.bovis_AF2122/97 VVAAILLSLQRIRSDPLGKLMFGSIHGGAGELAWLTESPLLADFATELTG
Rv1776c|M.tuberculosis_H37Rv VVAAILLSLQRIRSDPLGKLMFGSIHGGAGELAWLTESPLLADFATELTG
MMAR_2651|M.marinum_M VVAAIILSVQRIRADPLGQLMISSIHGGTQEVAWLADSPLLAGVASDLTG
MUL_3128|M.ulcerans_Agy99 VVAAIILSVQRIRADPLGQLMISSIHGGTQEVAWLADSPLLAGVASDLTG
MAB_1938c|M.abscessus_ATCC_199 AVVAITASLTAIRHDPVISTMIAT-MSPTSLGSYLNASSEIPRSASAFTG
* * :: :* *: : : *. . *: : *
MAV_0009|M.avium_104 PGHDNPLAAQWLIRVFLALWGWPLKDPAAERALVHRFLGASYRPGGERDS
Mflv_3474|M.gilvum_PYR-GCK TADADPLAAQWLIRVFLALWYWPMHDEEAEKAAVLRFLGPPY-AGAPDDP
Mvan_3780|M.vanbaalenii_PYR-1 IDDDDPQAAQWIVRVVLALLFWPVEDPAAEREMLQRFLIQRP--------
MSMEG_0676|M.smegmatis_MC2_155 VTD-DPQAAQWIVRVVMSLAVWPIGDAAAEAGLVERFVAPAFE-------
TH_0937|M.thermoresistible__bu ITD-DPEAARWIVRVVISMAYWPMADPRLEEQTIRRFVAPAFG-------
Mb1805c|M.bovis_AF2122/97 IAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAFAEQS----
Rv1776c|M.tuberculosis_H37Rv IAGGDPQGAKWVVRVVLSLMYWPAENDEAERRLVEKYVAPAFAEQS----
MMAR_2651|M.marinum_M LAGGDPHAAKWVVRIVLSLMYWPAESEDVERLMVEKFVAPVFAE------
MUL_3128|M.ulcerans_Agy99 LAGGDPHAARWVVRVVLSLMYWPAESEDVERLMVEKFVAPVFAE------
MAB_1938c|M.abscessus_ATCC_199 LAD--ETAAQWISRVVMALLFWPTSDPAQESEMIERFVYPVLKDATASRV
.*:*: *:.::: ** . * : :::
MAV_0009|M.avium_104 ICGA----------------------
Mflv_3474|M.gilvum_PYR-GCK --------------------------
Mvan_3780|M.vanbaalenii_PYR-1 --------------------------
MSMEG_0676|M.smegmatis_MC2_155 --------------------------
TH_0937|M.thermoresistible__bu --------------------------
Mb1805c|M.bovis_AF2122/97 --------------------------
Rv1776c|M.tuberculosis_H37Rv --------------------------
MMAR_2651|M.marinum_M --------------------------
MUL_3128|M.ulcerans_Agy99 --------------------------
MAB_1938c|M.abscessus_ATCC_199 SASATSESTISPARTATFDSSEDDSP