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MGEPSARATTPGTPMRRIAAACLVGSAIEFYDFLIYGTAAALVFPAVFFPRLGPTVATIASMATFATAFL SRPLGAAVFGYFGDRLGRKKTLVATLLIMGASTVSVGLVPSTASIGIAAPLLLTVLRLLQGFAVGAEWAG SVLLSAEYAPTDRRGWYGMFTLLGGGTAGILASLTFLAVNLTMGEHSPAFMHWGWRVPFLISSGLIGIAL YVRLNIDETPIFVEEKARHLVPKAPLTELLRLQRREIILVAGSFVGGMGFIYLGNTFLVMYAHNHLGYSR SFIWGIGALGGLTSMACVACSAWISDRVGRRRVMLWGLVACLPWAFVVIPLIDTGRPVCYVVAVLGMFGT AAVANGPTAAFVPELFATRYRYSGAAVAMNLAGIVGAAVPPLLAGTLLATYGSWAIGLMMASLVLASFVS VYLLPETRGAALDAAAAAEKVAAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1344 | - | - | 100% (444) | major facilitator family protein transporter |
| M. avium 104 | MAV_4059 | - | 1e-78 | 38.69% (442) | monoxygenase |
| M. avium 104 | MAV_4627 | - | 4e-68 | 36.34% (410) | major facilitator superfamily protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1232 | - | 1e-157 | 64.45% (422) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_2383 | - | 1e-86 | 44.88% (410) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1200 | - | 1e-157 | 64.45% (422) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3416 | - | 1e-111 | 48.24% (425) | membrane transporter |
| M. marinum M | MMAR_4238 | - | 1e-149 | 62.76% (427) | integral membrane transport protein |
| M. smegmatis MC2 155 | MSMEG_4886 | - | 6e-86 | 43.54% (418) | major facilitator family protein transporter |
| M. thermoresistible (build 8) | TH_3714 | - | 5e-89 | 42.38% (446) | PUTATIVE major facilitator superfamily MFS_1 |
| M. ulcerans Agy99 | MUL_0949 | - | 1e-148 | 62.53% (427) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_2899 | - | 6e-78 | 37.68% (422) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4238|M.marinum_M -----------------MSRVALACVVGSTVEYYDFCIYGTAAALVFPAV
MUL_0949|M.ulcerans_Agy99 -----------------MSRVALACVVGSTVEYYDFCIYGTAAALVFPAV
Mb1232|M.bovis_AF2122/97 -----------------MKRVALACLVGSAIEFYDFLIYGTAAALVFPTV
Rv1200|M.tuberculosis_H37Rv -----------------MKRVALACLVGSAIEFYDFLIYGTAAALVFPTV
MAV_1344|M.avium_104 ---MGEPSARATTPGTPMRRIAAACLVGSAIEFYDFLIYGTAAALVFPAV
MAB_3416|M.abscessus_ATCC_1997 MTSSPAEPRQMADGQVSPRRVFMASAVGSAIEFYDFYIYGTAAALVFPAV
Mflv_2383|M.gilvum_PYR-GCK -------MGPGGRTRVSPRRVAIASFVGTTVEFYDFLIYGTAAALVFPKL
MSMEG_4886|M.smegmatis_MC2_155 -------MATSTGVRVSPLRVAVASFIGTTVEFYDFLIYGTAAALVFPKL
TH_3714|M.thermoresistible__bu ----MSAEAATPTSRVTPRRVAVASFIGTTVEFYDFLIYGTAAALVFPKL
Mvan_2899|M.vanbaalenii_PYR-1 ------MNEASVADSALLRRVALSSLLGTAIEYYDFLVYGTMSALVFGLV
*: :. :*:::*:*** :*** :**** :
MMAR_4238|M.marinum_M FYPGLSPALATIASMGTFATAFLSRPLGAAVFGHFGDRLGRKKTLVATLL
MUL_0949|M.ulcerans_Agy99 FYPGLSPALATIASMGTFATAFLSRPLGAAVFGHFGDRLGRKKTLVATLL
Mb1232|M.bovis_AF2122/97 FFPHLDPTVAAVASMGTFAVAFLSRPFGAAVFGYFGDRLGRKKTLVATLL
Rv1200|M.tuberculosis_H37Rv FFPHLDPTVAAVASMGTFAVAFLSRPFGAAVFGYFGDRLGRKKTLVATLL
MAV_1344|M.avium_104 FFPRLGPTVATIASMATFATAFLSRPLGAAVFGYFGDRLGRKKTLVATLL
MAB_3416|M.abscessus_ATCC_1997 FFPNLSHSLALFASIATFSTAFLARPIGAALFGHYGDRFSRKGTLVVTLI
Mflv_2383|M.gilvum_PYR-GCK FFPNASPAAGILLSFATFGVGFIARPLGGIVFGHFGDRVGRRRMLVYSLV
MSMEG_4886|M.smegmatis_MC2_155 FFPQASPAAGILLSFATFGVGFIARPLGGIVFGHFGDRIGRKRMLVYSLV
TH_3714|M.thermoresistible__bu FFPTASPASGVLLSFATFGVGFFARPLGGIVFGHFGDRLGRKRMLVYSLV
Mvan_2899|M.vanbaalenii_PYR-1 FFPDSDPAVATIAAFGTLAAGYVARPVGGIVFGHFGDRIGRKSMLVLTMT
*:* . : . . ::.*:...:.:**.*. :**::***..*: ** ::
MMAR_4238|M.marinum_M IMALSTVTVGVVPSTATIGVSAPLILVALRLLQGFAVGGEWAGSALLSIE
MUL_0949|M.ulcerans_Agy99 IMALSTVTVGVVPSTATIGVSAPLILVALRLLQGFAVGGEWAGSALLSIE
Mb1232|M.bovis_AF2122/97 IMGLATVTVGLVPTTVAIGAAAPLILTTMRLLQGFAVGGEWAGSALLSAE
Rv1200|M.tuberculosis_H37Rv IMGLATVTVGLVPTTVAIGAAAPLILTTMRLLQGFAVGGEWAGSALLSAE
MAV_1344|M.avium_104 IMGASTVSVGLVPSTASIGIAAPLLLTVLRLLQGFAVGAEWAGSVLLSAE
MAB_3416|M.abscessus_ATCC_1997 TMGLATMAVGLVPGAATIGAAAPTAIVILRLVQGLAVGGEWSGAALLSAE
Mflv_2383|M.gilvum_PYR-GCK GMGVSTVLIGVLPTYAQIGLAAPILLTVLRLAQGFAVGGEWGGATLMAVE
MSMEG_4886|M.smegmatis_MC2_155 GMGVSTVLIGLLPSYAQIGLAAPVLLTVLRLCQGFAVGGEWGGATLMAVE
TH_3714|M.thermoresistible__bu GMGVATVLIGLLPTYAQIGMAAPALLTLLRLAQGFAMGGEWGGATLMAVE
Mvan_2899|M.vanbaalenii_PYR-1 LMGTASFLIGLLPSFAAVGVAAPILLVALRVIQGVAIGGEWGGATLMVTE
*. ::. :*::* . :* :** :. :*: **.*:*.**.*:.*: *
MMAR_4238|M.marinum_M SAPAHKRGYYGMFTVLGGGVALVVSGLTFLGVNYTIGESSSAFLQWGWRV
MUL_0949|M.ulcerans_Agy99 SAPAHKRGYYGMFTVLGGGVALVVSGLTFLGVNYTIGESSSALLQWGWRV
Mb1232|M.bovis_AF2122/97 YAPASKRGWYGMFTVVGGGIALVLTSLTFLGVNYTIGESSPTFMQWGWRI
Rv1200|M.tuberculosis_H37Rv YAPASKRGWYGMFTVVGGGIALVLTSLTFLGVNYTIGESSPTFMQWGWRI
MAV_1344|M.avium_104 YAPTDRRGWYGMFTLLGGGTAGILASLTFLAVNLTMGEHSPAFMHWGWRV
MAB_3416|M.abscessus_ATCC_1997 YSPSQNRGRAATAVPIGTSTGLLLSSLVFLIVSLTIGEDSPAFLSWGWRV
Mflv_2383|M.gilvum_PYR-GCK HATADRRGFYGAFPQMGAPAQTAAATLAFYLAARLPDDQ---FLAWGWRI
MSMEG_4886|M.smegmatis_MC2_155 HASADRRGFYGAFPQMGAPAGTASATLAFFLASQLPDAQ---FLAWGWRL
TH_3714|M.thermoresistible__bu HASADRKGFYGAFPQMGAPAGTATATLAFFAVSRLPDGQ---FLSWGWRL
Mvan_2899|M.vanbaalenii_PYR-1 HAEAHRRGFWNGVMQMGSPIGSLLSVAVVTVITLLPDES---FLSWGWRI
: : .:* :* : .. . :: ****:
MMAR_4238|M.marinum_M PFLLSALLIAFALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVLC
MUL_0949|M.ulcerans_Agy99 PFLLSALLIAFALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVLC
Mb1232|M.bovis_AF2122/97 PFLVSAALIAVALYVRFNIDETPVFAR--ERADEKTRLGPAETPIAQVLR
Rv1200|M.tuberculosis_H37Rv PFLVSAALIAVALYVRFNIDETPVFAR--ERADEKTRLGPAETPIAQVLR
MAV_1344|M.avium_104 PFLISSGLIGIALYVRLNIDETPIFVE------EKARHLVPKAPLTELLR
MAB_3416|M.abscessus_ATCC_1997 PFIASGLLVAVGLYIRLQIAETPQFVE------AKAHHQLVKSPLRHVIT
Mflv_2383|M.gilvum_PYR-GCK PFLVSAILIVIGLVVRLTVTESPHFAE----LQRRSE--VTRTPIVAAFR
MSMEG_4886|M.smegmatis_MC2_155 PFLFSAALIVIGLVIRLKLTESPEFAA----VVQNSA--VRRMPIVEAFR
TH_3714|M.thermoresistible__bu PFLLSAVLIGIGLAVRLTLTESPDFAA----VQARSA--VHRMPIAEAFR
Mvan_2899|M.vanbaalenii_PYR-1 PFLVSLLLLAVGIYVRLSVTESPVFEA----ARKEAAGNAPRVPFVEILR
**: * *: ..: :*: : *:* * . . *: :
MMAR_4238|M.marinum_M RQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGYSRNLVLLIGVLGG
MUL_0949|M.ulcerans_Agy99 RQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLGYSRNLVLLIGVLGG
Mb1232|M.bovis_AF2122/97 RQRREIVLAAGSAVCCFGFVYLASTYLASYAQTRLGYSRGSILFDSVLGG
Rv1200|M.tuberculosis_H37Rv RQRREIVLAAGSAVCCFGFVYLASTYLASYAQTRLGYSRGSILFDSVLGG
MAV_1344|M.avium_104 LQRREIILVAGSFVGGMGFIYLGNTFLVMYAHNHLGYSRSFIWGIGALGG
MAB_3416|M.abscessus_ATCC_1997 ESPRTLVLTSGTMLIIFTLSFMTNTYFPGFARSELHFSRAAILAAGALGA
Mflv_2383|M.gilvum_PYR-GCK RHWRQILLVAGAYLSQGIFAYICVAYLVSYATTVAEIPRDWALLGVFLGA
MSMEG_4886|M.smegmatis_MC2_155 RHWRQIVLVAGAYLSQGVFAYICVAYLVSYATTAAGIDRTAALFGVFVAA
TH_3714|M.thermoresistible__bu RHRRQILLVAGAYLSQGVFAYICVAYLVSYGTSVAGIDRTATLFGVSVAA
Mvan_2899|M.vanbaalenii_PYR-1 RP-RTLVLACAVGIGPFALTALISTYMISYATAIG-YHRTDVMTALIFTS
* ::*... : : ::: :. * . .
MMAR_4238|M.marinum_M LVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLVMPLIGSGDTVGFT
MUL_0949|M.ulcerans_Agy99 LVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLVMPLIGSGDTVGFT
Mb1232|M.bovis_AF2122/97 LLCIVFTALSSALCDQLGRRRVLLAGWAVALPWSLLVMPLIDSGSPSLFA
Rv1200|M.tuberculosis_H37Rv LLCIVFTALSSALCDQLGRRRVLLAGWAVALPWSLLVMPLIDSGSPSLFA
MAV_1344|M.avium_104 LTSMACVACSAWISDRVGRRRVMLWGLVACLPWAFVVIPLIDTGRPVCYV
MAB_3416|M.abscessus_ATCC_1997 VVLMVSATAGGILSDRLGRRTVILSSMTLTLPWTLLVTPLLTSGPFWAYL
Mflv_2383|M.gilvum_PYR-GCK VVAVATYPLFGALSDRVGRKPLYLAGVIAMALAVVPTFALINTGRPVMFV
MSMEG_4886|M.smegmatis_MC2_155 LVAVAAYPAFGAWSDVVGRKRLFLVGVALMAASVFPVFALIDTGSALLFG
TH_3714|M.thermoresistible__bu VLAVVMYPLFGSLSDTFGRKPLFLAGVIAMGVSIGPAFALIDTGRPALFL
Mvan_2899|M.vanbaalenii_PYR-1 LTGLIAIPFFSALSDHVGRRLVMVAGAIGIIGYAWPFYALVDMRSQAYLT
: : . . .* .**: : : . .*:
MMAR_4238|M.marinum_M VALLGLYAVAAS-GFGPAASLIPELFATRYRYTGTALALNVAGIVGGAAP
MUL_0949|M.ulcerans_Agy99 VALLGLYAVAAS-GFGPAASLIPELFATRYRYTGTALALNVAGIVGGAAP
Mb1232|M.bovis_AF2122/97 VAVVGMYAIGGF-GFGPTASFIPELFATSYRYTGSALAANLAGVAGGALP
Rv1200|M.tuberculosis_H37Rv VAVVGMYAIGGF-GFGPTASFIPELFATSYRYTGSALAANLAGVAGGALP
MAV_1344|M.avium_104 VAVLGMFGTAAV-ANGPTAAFVPELFATRYRYSGAAVAMNLAGIVGAAVP
MAB_3416|M.abscessus_ATCC_1997 AAMALTYVLFGL-AFGPMASFLPESYPVGTRYSGTGVAFNVAGVFGGAIP
Mflv_2383|M.gilvum_PYR-GCK LALVLIFGLAMAPAAGVTGALFSMAFDADVRYSGVSVGYTLSQVLGSAFA
MSMEG_4886|M.smegmatis_MC2_155 VALVLVFGLAMAPAAGVTGALFSLAFDADVRYSGVSIGYTLSQVLGSAFA
TH_3714|M.thermoresistible__bu VALVLVFGLAMAPAAGVTGALFAMTFDADVRYSGVSIGYTLSQVLGSAFA
Mvan_2899|M.vanbaalenii_PYR-1 AAMVIAQ-LIQSMMYAPLGALFSEMFGTTVRYTGASMGYQLAALLGAGFT
*: . .::.. : . **:* .:. :: : *.. .
MMAR_4238|M.marinum_M PLIAGTLLASYGS-SAVGLMMTALVAASLLCTYLLPETAGAPLTAA----
MUL_0949|M.ulcerans_Agy99 PLIAGTLLASYGS-SAVGLMMTALVAASLLCTYLLPETAGAPLTAA----
Mb1232|M.bovis_AF2122/97 PVIAGALVATYGS-WAIGVMLAILALISLVCTYRLPETAGSALVSR----
Rv1200|M.tuberculosis_H37Rv PVIAGALVATYGS-WAIGVMLAILALISLVCTYRLPETAGSALVSR----
MAV_1344|M.avium_104 PLLAGTLLATYGS-WAIGLMMASLVLASFVSVYLLPETRGAALDAAAAAE
MAB_3416|M.abscessus_ATCC_1997 PLIAGPLQNTLGS-WAVGLMLLVICAISVASISGMRETWAGSAR------
Mflv_2383|M.gilvum_PYR-GCK PTIATALYAATGSSNSIAAYLIAASAVSAVAVCFMPGGWRAAPAEARPEH
MSMEG_4886|M.smegmatis_MC2_155 PTIAAALYAAAQSSDSIAWYLVAVSAISVVAGTLLPS-DRSAPEAAVVKG
TH_3714|M.thermoresistible__bu PTIAAALYAATESSGSIVAYLIGVSVISAVSVCLLPGGWGRTGDQPATEV
Mvan_2899|M.vanbaalenii_PYR-1 PLIASALHAQEVSRTPLVALAAGCGLVTVVAVWRISETRGTDLTTV----
* :* .* * .: : . :
MMAR_4238|M.marinum_M ------------
MUL_0949|M.ulcerans_Agy99 ------------
Mb1232|M.bovis_AF2122/97 ------------
Rv1200|M.tuberculosis_H37Rv ------------
MAV_1344|M.avium_104 KVAAR-------
MAB_3416|M.abscessus_ATCC_1997 ------------
Mflv_2383|M.gilvum_PYR-GCK TPTAPTG-----
MSMEG_4886|M.smegmatis_MC2_155 ------------
TH_3714|M.thermoresistible__bu PASVRPMVSGPD
Mvan_2899|M.vanbaalenii_PYR-1 ------------