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PSNHISLVHGWLPVAIQAVAGITLSLAAGWRSWRWRLLWLPSAAVLGVTTAVGAHRCIITRAPQALFVWI ALAGMAIAILLLGWRGARWWRRGLSILAVPLCLLCSLLVLNQWVGYFQTVQSAWSQFTSGPLPDQTDRAT VTTLAARGAKPPHGSLVPVQIPEDASHFKHREELVYLPPAWFASYPPPQLPTVLMIGGMVNTPADWVRAG NAVDTVDAFAAAHGGNSPVLVFADPGGALDNDTECVNGSRGNAADHLTKDVVPYMISTFGVSKDPSRWGI VGWSMGGTCSVDLTVMHPALFSAFVDIDGDLTPNTGTREQTIADLFDGSADAWATFDPATVIARHGRYTG VSGWFAISSTGSPSPRRDVDSTAMAVAGRAAADPGDQAAAAASLCALGRANGIDCAVVAQGGHHDWPTAG TAFATALPWLAGQLGTPGASRISLPGNASRQAL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0936 | - | - | 100% (454) | putative esterase family protein |
| M. avium 104 | MAV_3129 | - | e-180 | 67.41% (448) | putative esterase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1666c | - | 0.0 | 65.95% (464) | hypothetical protein Mb1666c |
| M. gilvum PYR-GCK | Mflv_3545 | - | 1e-151 | 57.21% (451) | putative esterase |
| M. tuberculosis H37Rv | Rv1639c | - | 0.0 | 65.95% (464) | hypothetical protein Rv1639c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2318c | - | 1e-139 | 53.52% (454) | hypothetical protein MAB_2318c |
| M. marinum M | MMAR_2446 | - | 1e-177 | 65.28% (458) | hypothetical protein MMAR_2446 |
| M. smegmatis MC2 155 | MSMEG_3797 | - | 1e-158 | 57.84% (453) | putative esterase family protein |
| M. thermoresistible (build 8) | TH_2468 | - | 8e-05 | 27.03% (111) | PUTATIVE putative esterase |
| M. ulcerans Agy99 | MUL_1625 | - | 1e-174 | 65.07% (458) | hypothetical protein MUL_1625 |
| M. vanbaalenii PYR-1 | Mvan_3331 | - | 1e-159 | 59.11% (450) | putative esterase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1666c|M.bovis_AF2122/97 MAQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLVLAAGWR
Rv1639c|M.tuberculosis_H37Rv MAQNELVTASTPPAATQPLAVGHTSLMHGWVPLAVQVVTAVVLVLAAGWR
MMAR_2446|M.marinum_M ------MTTS-PPALARVLASTHTSLMHGWVPVTVQVVTAIVLLLAIGWR
MUL_1625|M.ulcerans_Agy99 MFDNETVTTS-PPALARVLASTHTSLMHGWVPDTVQVVTAIVLLLAIGWR
MAV_0936|M.avium_104 ------------------MPSNHISLVHGWLPVAIQAVAGITLSLAAGWR
Mflv_3545|M.gilvum_PYR-GCK -------------MTLPYLARHDLSLMHGWVPVSVQILAAAAMIAAVGWR
Mvan_3331|M.vanbaalenii_PYR-1 --------------------------MHGWLPVAVQILAVVAVVTAIGRR
MSMEG_3797|M.smegmatis_MC2_155 -------------MTFT----HHLSLMHGWVPTTVQVVTAVILIAAVGRR
MAB_2318c|M.abscessus_ATCC_199 ---------------MSAVSGHDISLLHGNFPVSMQVITGFALVIAIGLR
TH_2468|M.thermoresistible__bu --------------------------------------------------
Mb1666c|M.bovis_AF2122/97 SRHWQRRWLPTAAAIGATLAWGTRWYVTGNGLAN--ERPPSTLWIWVALT
Rv1639c|M.tuberculosis_H37Rv SRHWQRRWLPTAAAIGATLAWGTRWYVTGNGLAN--ERPPSTLWIWVALT
MMAR_2446|M.marinum_M S----RRRLPAAVIFGAIAAWATRWYLG--TLAN--EPVPAALWVWVGLT
MUL_1625|M.ulcerans_Agy99 S----RRRLPAAVIFGAIAAWVTRWYLG--TLAN--EPVPAALWVWVGLT
MAV_0936|M.avium_104 SWRWRLLWLPSAAVLGVTTAVGAHRCII--------TRAPQALFVWIALA
Mflv_3545|M.gilvum_PYR-GCK TRRWRRVWVPWAASIGGGLAFTTYCYIRSAGVADESNPAPPTLWVWIALS
Mvan_3331|M.vanbaalenii_PYR-1 TRRWRLVWVPWSALIGVVLAVAAYCYIASAGVADDSNPAPHTLWVWIALS
MSMEG_3797|M.smegmatis_MC2_155 TWRWHLIWLPAAAAVGAVLALGTFWYIQSEGLAG--NPAPRSLWVWIAIS
MAB_2318c|M.abscessus_ATCC_199 TRRWFRRWVPVAVGIGVALAGWAYWYIQSEGWADRGNPAPLMLWVWIALT
TH_2468|M.thermoresistible__bu --------------------------------------------------
Mb1666c|M.bovis_AF2122/97 GAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGYFPTVQTA
Rv1639c|M.tuberculosis_H37Rv GAAATVLILGWRSARWWRRGASLLAVPLCLLSATLTLNLWVGYFPTVQTA
MMAR_2446|M.marinum_M AVAAAMLVVGWRGARWRRRTASLVAVPFCALCAALGLNIWVGYFPTVQAA
MUL_1625|M.ulcerans_Agy99 AVAAAMLVVGWRGARWRRRTASLVAVPLCALCAALGLNIWVGYFPTVQAA
MAV_0936|M.avium_104 GMAIAILLLGWRGARWWRRGLSILAVPLCLLCSLLVLNQWVGYFQTVQSA
Mflv_3545|M.gilvum_PYR-GCK GTAFGVLVAGWRGARRWRRTASALAVPLCALAAALVLNLWVGYFPTVDTA
Mvan_3331|M.vanbaalenii_PYR-1 GFAFGVLVSGWRGARWWRRTAATLAVPLCVLSAALVVNLWVGYFPTVQTA
MSMEG_3797|M.smegmatis_MC2_155 GATVVVLVAGWPRSRWWRRGASALAIPMSVLCAALALNLWVGYFPWVQTA
MAB_2318c|M.abscessus_ATCC_199 GVAATVLVVGWRTARWWRRAVALTAVPLTILSGSLMLNQWVGYVRSIQSG
TH_2468|M.thermoresistible__bu --------------------MNLLSVFFRMMCAAVLAAVGVTVSTATATA
:: : :.. : * :.
Mb1666c|M.bovis_AF2122/97 WNQLTSGPLPDQADQAAVAALA--HSGVRPSHGTLLPVVIPSDASHFKHR
Rv1639c|M.tuberculosis_H37Rv WNQLTSGPLPDQADQAAVAALA--HSGVRPSHGTLLPVVIPSDASHFKHR
MMAR_2446|M.marinum_M WNQLSSGPLPDQADPAAVVAMA--GKGVRPAHGSMVPVAIPSNASHFKHR
MUL_1625|M.ulcerans_Agy99 WNQLSSGPLPDQADPAAVVAMA--GKGVRPAHGSMVPVAIPSNASHFKHR
MAV_0936|M.avium_104 WSQFTSGPLPDQTDRATVTTLA--ARGAKPPHGSLVPVQIPEDASHFKHR
Mflv_3545|M.gilvum_PYR-GCK WNQLTAGPVPDQTDQVVVAALQ--KQHAVPIKGSVVPVQIPSTASGFTHR
Mvan_3331|M.vanbaalenii_PYR-1 WNQLTAGPLPDQTDAVTVAAMQ--KQHAMPVKGSLVAVDIPDTASGFRHR
MSMEG_3797|M.smegmatis_MC2_155 WNQLTAGPLPDQTDQVTVAAMQ--RDGAVPAKGTVVPVQIPNTASGFRHR
MAB_2318c|M.abscessus_ATCC_199 WAQLTAGPLPNQADMATVTAAREERRGPTMTKGKLVPVDIPADASGFRHR
TH_2468|M.thermoresistible__bu QPAVEQLMVP------------------SAAMGRDIPVSFMAGG------
. :* * :.* : .
Mb1666c|M.bovis_AF2122/97 GELVYLPPAWFDREHRSENPPPPQLPTVMMIGGQFNTPADWARAGNAVKT
Rv1639c|M.tuberculosis_H37Rv GELVYLPPAWFDREHRSENPPPPQLPTVMMIGGQFNTPADWARAGNAVKT
MMAR_2446|M.marinum_M GELVYLPPAWFA------SYPPPRLPAVMMIGGQFNTPADWARAGNAVRT
MUL_1625|M.ulcerans_Agy99 GELVYLPPAWFA------SYPPPRLPAVMMIGGQFNTPADWARAGNAVRT
MAV_0936|M.avium_104 EELVYLPPAWFA------SYPPPQLPTVLMIGGMVNTPADWVRAGNAVDT
Mflv_3545|M.gilvum_PYR-GCK QEFVYVPPAWFA------SDPPPALPVVMMIGGEFNTPADWLRAGEAVKI
Mvan_3331|M.vanbaalenii_PYR-1 QEWVYLPPAWYA------SDPPPALPTVMMIGGEFNTPADWLRAGGAART
MSMEG_3797|M.smegmatis_MC2_155 QEYVYLPPAWFA------ANPPPKLPTVMMIGGEFNTPADWMRAGNVIST
MAB_2318c|M.abscessus_ATCC_199 KEIVYLPPAWFD-------STRTELPTIMMIGGEFNTPSDWIRSGNAVEV
TH_2468|M.thermoresistible__bu ----------------------PHAVVLLDAFNAAPDVSNWVTVGNAMNT
. .:: . ::* * .
Mb1666c|M.bovis_AF2122/97 LDDFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYM
Rv1639c|M.tuberculosis_H37Rv LDDFAAAHSGNAPVVVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYM
MMAR_2446|M.marinum_M IDDFALAHNGNAPVLVFVDSGGAFNNDTECVNGRRGNAADHLTKDVVPYM
MUL_1625|M.ulcerans_Agy99 IDDFALAHNGNAPVLVFVDSGGAFNNDTERVNGRRGNAADHLTKDVVPYM
MAV_0936|M.avium_104 VDAFAAAHGGNSPVLVFADPGGALDNDTECVNGSRGNAADHLTKDVVPYM
Mflv_3545|M.gilvum_PYR-GCK LDEFARAHRGYAPVAVFVDPGGTFDNDTECVNGPRGNAADHLVKDVVPYL
Mvan_3331|M.vanbaalenii_PYR-1 LDAFAAAHGGYAPVVVFVDPGGTFNNDTECVNGTRGNSADHLVKDVVPYM
MSMEG_3797|M.smegmatis_MC2_155 VDAFAASHHGFAPVLVFVDPGGAFNNDTECVNGSRGNAADHLTKDVVPYL
MAB_2318c|M.abscessus_ATCC_199 ADAFASQHGGNAPVMVFVDAGGSFNNDTECVNGPRGNSADHLTNDVVPFM
TH_2468|M.thermoresistible__bu LAGKG--------ISVVAPAGGAWSLYTNWENDGSKQWETFLANELPDWL
. : *.. .**: . *: *. : .*.::: ::
Mb1666c|M.bovis_AF2122/97 VSKFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDFYPNA
Rv1639c|M.tuberculosis_H37Rv VSKFGVSPEQTSWGIVGWSMGGTCAVDLTVMHPTLFSAFVDIAGDFYPNA
MMAR_2446|M.marinum_M ISAFGVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDFYPNA
MUL_1625|M.ulcerans_Agy99 ISAFDVSPEPSNWGIVGWSMGGTCAVDLTVMHPSLFSAFVDVAGDFYPNA
MAV_0936|M.avium_104 ISTFGVSKDPSRWGIVGWSMGGTCSVDLTVMHPALFSAFVDIDGDLTPNT
Mflv_3545|M.gilvum_PYR-GCK KSQYGVSPAAAGWGVVGWSMGGTCAVDLTVMHPDIFSTFVDIAGDAAPNA
Mvan_3331|M.vanbaalenii_PYR-1 KSHFGVSSAAANWGVVGWSMGGTCAVDLTVMHPEVFSAFVDIAGDAAPNA
MSMEG_3797|M.smegmatis_MC2_155 EAHYGVSAAAAHWGIVGWSMGGTCAVDLAVMHPDMFSAFVDIAGDLTPNS
MAB_2318c|M.abscessus_ATCC_199 ISRFGVSPRPQNWGVVGWSMGGTCAVTLAAKHPELFSAFEDIAGDMSPNT
TH_2468|M.thermoresistible__bu AANKGLAPG--GHGIVGASQGGTAALTLAAFYPNRYRYAGSMSGFLTPSA
: .:: *:** * ***.:: *:. :* : .: * *.:
Mb1666c|M.bovis_AF2122/97 GNKTQTIVRLFG--GNEDAWSAFDPTTVITRHGSYTGLSGWFAISSP-GP
Rv1639c|M.tuberculosis_H37Rv GNKTQTIVRLFG--GNEDAWSAFDPTTVITRHGSYTGLSGWFAISSP-GP
MMAR_2446|M.marinum_M GNKAETITRLFG--GNADAWAAFDPTTVINRHGQYTGISGWFSISVPAGP
MUL_1625|M.ulcerans_Agy99 GNKAETITRLFG--GNADAWAAFDPTTVINRHGQYTGISGWFSISVPAGP
MAV_0936|M.avium_104 GTREQTIADLFD--GSADAWATFDPATVIARHGRYTGVSGWFAISST-GS
Mflv_3545|M.gilvum_PYR-GCK GTRNETVQRLFG--GDSAAYAAFDPTAVMERHGPYRGVEGWFAVN-----
Mvan_3331|M.vanbaalenii_PYR-1 GTQAETVDRLFG--GDTAAYTSFDPTAVMTRHGPYRGVAGWFDVNGA---
MSMEG_3797|M.smegmatis_MC2_155 GTKAQTIDRLFG--GNAAAWDAFDPTTVINRHGHYQDVAGWFDVN-----
MAB_2318c|M.abscessus_ATCC_199 GNKAQTIARLFG--GDAGAWEQFDPATVMTRHGRYANTAGWFDVNGLHRA
TH_2468|M.thermoresistible__bu TALNGAITAGLQRFGGVETTNMWGLPQAGRWKWRDPDVHAQLLVNNN---
:: : *. : :. . . : . . : :.
Mb1666c|M.bovis_AF2122/97 PSP-DNAVADTTTMRLAGRDAAANPGNQAAAANALCALGRANGIYCAVVP
Rv1639c|M.tuberculosis_H37Rv PSP-DNAVADTTTMRLAGRDAAANPGNQAAAANALCALGRANGIYCAVVP
MMAR_2446|M.marinum_M GAPRDVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDCAVVP
MUL_1625|M.ulcerans_Agy99 GAPRDVAITDPAVMRLAGREAAANPSNQTAAANSLCALGRANGIDCAVVP
MAV_0936|M.avium_104 PSP--RRDVDSTAMAVAGR-AAADPGDQAAAAASLCALGRANGIDCAVVA
Mflv_3545|M.gilvum_PYR-GCK -----------------AVPGAATPNEQAVSAASLCGVGSRSGIACAVVS
Mvan_3331|M.vanbaalenii_PYR-1 ----------------VAVSATAQPNDQAVAASSLCATGGRSGIDCAVVS
MSMEG_3797|M.smegmatis_MC2_155 -----------------TGGPGTAPNDQAKAANSLCTLCSSHGIACAVQA
MAB_2318c|M.abscessus_ATCC_199 GSG-----AITSTGASPGTAANVPLSDQDRAAHKLCEVATAQGIACTVQH
TH_2468|M.thermoresistible__bu --------TRLWVFSPQTLTAADPAAMIGYADQAQGSNRTFYAHYRQIGG
: . :
Mb1666c|M.bovis_AF2122/97 QPGKHDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTT---QQIAGTGR
Rv1639c|M.tuberculosis_H37Rv QPGKHDWPFADRVFAAALPWLAGQLATPGVPKIPLPGTT---QQIAGTGR
MMAR_2446|M.marinum_M QPGRHDWPFADQVFARALPWLAGQVGTPGVPRIPLPGTASPATQVVPAGR
MUL_1625|M.ulcerans_Agy99 QPGRHDWPFADQVFARALPWLAGQLGTPGVPRIPLPGTASPATQEVPAGR
MAV_0936|M.avium_104 QGGHHDWPTAGTAFATALPWLAGQLGTPGASRISLPGNAS--RQAL----
Mflv_3545|M.gilvum_PYR-GCK RPGNHDWPFASTAFATALPWLAARIGTPGVPQTGFPGTVHG---------
Mvan_3331|M.vanbaalenii_PYR-1 QPGNHDWPFASTAFTSALPWLAGRIGTPGVPQIDLPRTVSG---------
MSMEG_3797|M.smegmatis_MC2_155 QPGTHDWPFATQAFKASLPWLAGAIGTPDVPVVGLPASAPSAPAFIETGK
MAB_2318c|M.abscessus_ATCC_199 KPGEHKWPFAQTAFTSALPWMAGRIGTPTVPDMPLPR-------------
TH_2468|M.thermoresistible__bu RNGHFDFPTSGDHGWSSWGPELGKMSGDLVAAIR----------------
: * ..:* : : . :. ..
Mb1666c|M.bovis_AF2122/97 -----
Rv1639c|M.tuberculosis_H37Rv -----
MMAR_2446|M.marinum_M -----
MUL_1625|M.ulcerans_Agy99 -----
MAV_0936|M.avium_104 -----
Mflv_3545|M.gilvum_PYR-GCK -----
Mvan_3331|M.vanbaalenii_PYR-1 -----
MSMEG_3797|M.smegmatis_MC2_155 TAGPK
MAB_2318c|M.abscessus_ATCC_199 -----
TH_2468|M.thermoresistible__bu -----